This is a Validated Antibody Database (VAD) review about rat Itgb3, based on 33 published articles (read how Labome selects the articles), using Itgb3 antibody in all methods. It is aimed to help Labome visitors find the most suited Itgb3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Itgb3 synonym: GPIIIa

Santa Cruz Biotechnology
mouse monoclonal (D-11)
  • immunoprecipitation; human; 1:100; loading ...; fig 6e
  • immunocytochemistry; human; 1:200; loading ...; fig s7b
  • western blot; human; 1:2000; loading ...; fig 6a
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz, sc-365679) was used in immunoprecipitation on human samples at 1:100 (fig 6e), in immunocytochemistry on human samples at 1:200 (fig s7b) and in western blot on human samples at 1:2000 (fig 6a). iScience (2022) ncbi
mouse monoclonal (D-11)
  • western blot; human; 1:1000; fig 6e
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz Biotechnology, sc-365679) was used in western blot on human samples at 1:1000 (fig 6e). Cell Mol Life Sci (2022) ncbi
mouse monoclonal (23C6)
  • immunohistochemistry - paraffin section; rat; loading ...; fig 6f
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz, sc-7312) was used in immunohistochemistry - paraffin section on rat samples (fig 6f). PLoS ONE (2021) ncbi
mouse monoclonal (D-11)
  • western blot; mouse; loading ...; fig 1a
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz Technology, sc-365679) was used in western blot on mouse samples (fig 1a). Brain Res (2018) ncbi
mouse monoclonal (B-7)
  • western blot; human; 1:200; loading ...; fig 5a
Santa Cruz Biotechnology Itgb3 antibody (SantaCruz, sc-46655) was used in western blot on human samples at 1:200 (fig 5a). Oncotarget (2016) ncbi
mouse monoclonal (23C6)
  • immunocytochemistry; human; fig 3
In order to study inhibition of the FAK/PI3K/Akt/mTOR signaling pathway through av-beta-3 integrin interaction by the anti-tumor NC1 domain of collagen XIX, Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz, sc7312) was used in immunocytochemistry on human samples (fig 3). Oncotarget (2016) ncbi
mouse monoclonal (SAP)
  • western blot; human
In order to determine the role of growth factors in EMT, Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz, SAP) was used in western blot on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (B-7)
  • western blot; human
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz Biotechnology, sc-46655) was used in western blot on human samples . Colloids Surf B Biointerfaces (2015) ncbi
mouse monoclonal (23C6)
  • immunoprecipitation; human; 1:200
  • western blot; human; 1:200; fig 1
In order to test if integrin alphavbeta3 signaling promotes the release of intracellular calcium and contributes to viral entry and spread, Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz Biotechnology, sc7312) was used in immunoprecipitation on human samples at 1:200 and in western blot on human samples at 1:200 (fig 1). J Virol (2014) ncbi
mouse monoclonal (F-11)
  • immunohistochemistry; rat; 1:100
  • western blot; rat; 1:2000
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz Biotechnology, sc-7311) was used in immunohistochemistry on rat samples at 1:100 and in western blot on rat samples at 1:2000. Cell Tissue Res (2014) ncbi
mouse monoclonal (BV4)
  • flow cytometry; human
Santa Cruz Biotechnology Itgb3 antibody (Santa Cruz, sc-52685) was used in flow cytometry on human samples . Biomaterials (2014) ncbi
mouse monoclonal (23C6)
  • western blot; mouse
In order to study the role of the Rac1 GTPase the shaping of the ocular lens, Santa Cruz Biotechnology Itgb3 antibody (Santa, SC-7312) was used in western blot on mouse samples . Dev Biol (2011) ncbi
BioLegend
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; 1:200; loading ...; fig s4-1b
BioLegend Itgb3 antibody (BioLegend, 104307) was used in flow cytometry on mouse samples at 1:200 (fig s4-1b). elife (2022) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse
BioLegend Itgb3 antibody (Biolegend, 104302) was used in flow cytometry on mouse samples . Cancer Cell (2021) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; loading ...; fig 4a
BioLegend Itgb3 antibody (Biolegend, 2C9G2) was used in flow cytometry on mouse samples (fig 4a). J Exp Med (2018) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; fig 3
BioLegend Itgb3 antibody (Biolegend, 2C9.G2) was used in flow cytometry on mouse samples (fig 3). PLoS ONE (2016) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; 1:100; fig 2
BioLegend Itgb3 antibody (Biolegend, 104308) was used in flow cytometry on mouse samples at 1:100 (fig 2). J Hematol Oncol (2016) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • flow cytometry; mouse; 1:10
BioLegend Itgb3 antibody (Biolegend, 104308) was used in flow cytometry on mouse samples at 1:10. Nature (2016) ncbi
hamsters monoclonal (2C9.G2 (HMβ3-1))
  • blocking or activating experiments; mouse; 10 ug/ml; fig 5
In order to report that Thy-1 is a regulator of fibroblast rigidity sensing, BioLegend Itgb3 antibody (BioLegend, 2C9.G2) was used in blocking or activating experiments on mouse samples at 10 ug/ml (fig 5). J Cell Biol (2015) ncbi
Abcam
mouse monoclonal (BV3)
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 2c
Abcam Itgb3 antibody (Abcam, ab7166) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 2c). Invest Ophthalmol Vis Sci (2019) ncbi
domestic rabbit monoclonal (EPR2342)
  • western blot; human; 1:1000; loading ...; fig 1s1a
  • western blot; mouse; 1:1000; fig 1s1a
Abcam Itgb3 antibody (Abcam, ab119992) was used in western blot on human samples at 1:1000 (fig 1s1a) and in western blot on mouse samples at 1:1000 (fig 1s1a). elife (2019) ncbi
domestic rabbit monoclonal (EPR2342)
  • western blot; human; 1:1000; loading ...; fig 4d
In order to determine if the extracellular matrix components of human skin fibroblasts change under non-stretch, static stretch, or cyclic stretch conditions, Abcam Itgb3 antibody (Abcam, ab119992) was used in western blot on human samples at 1:1000 (fig 4d). Exp Ther Med (2016) ncbi
mouse monoclonal (BV3)
Abcam Itgb3 antibody (Abcam, ab7166) was used . Theranostics (2016) ncbi
mouse monoclonal (BV3)
  • immunohistochemistry - paraffin section; rat; 1:50; fig 5c
Abcam Itgb3 antibody (Abcam, ab7166) was used in immunohistochemistry - paraffin section on rat samples at 1:50 (fig 5c). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR2342)
  • western blot; human
Abcam Itgb3 antibody (Abcam, ab119992) was used in western blot on human samples . Int J Mol Sci (2014) ncbi
mouse monoclonal (BV3)
  • immunohistochemistry - paraffin section; pigs
Abcam Itgb3 antibody (Abcam, ab7166) was used in immunohistochemistry - paraffin section on pigs samples . Islets (2013) ncbi
Invitrogen
hamsters monoclonal (2C9.G3)
  • flow cytometry; human; 1:50; fig 2a
Invitrogen Itgb3 antibody (eBioscience/Thermo, 12-0611-82) was used in flow cytometry on human samples at 1:50 (fig 2a). Stem Cells (2019) ncbi
hamsters monoclonal (2C9.G3)
  • flow cytometry; mouse; loading ...; fig 1c
Invitrogen Itgb3 antibody (Thermofisher, 2C9.G2) was used in flow cytometry on mouse samples (fig 1c). J Leukoc Biol (2019) ncbi
mouse monoclonal (F11)
  • flow cytometry; mouse; 1:1000; loading ...; fig 1h
In order to test if senescent stromal cells contribute to tumorigenesis, Invitrogen Itgb3 antibody (eBioscience, F11) was used in flow cytometry on mouse samples at 1:1000 (fig 1h). Nat Commun (2016) ncbi
mouse monoclonal (23C6)
  • immunocytochemistry; human
In order to study voltage-dependent anion channels in human osteoclasts, Invitrogen Itgb3 antibody (Endogen, 23C6) was used in immunocytochemistry on human samples . Cell Biol Int (2013) ncbi
mouse monoclonal (23C6)
  • blocking or activating experiments; human
In order to investigate translocation of Mycobacterium tuberculosis across the lung, Invitrogen Itgb3 antibody (Biosource, 23C6) was used in blocking or activating experiments on human samples . Infect Immun (2002) ncbi
Novus Biologicals
domestic rabbit monoclonal (SJ19-09)
  • western blot; mouse; 1:1000; loading ...; fig 5d
Novus Biologicals Itgb3 antibody (Novus Biologicals, SJ19-09) was used in western blot on mouse samples at 1:1000 (fig 5d). Theranostics (2021) ncbi
mouse monoclonal (BV4)
  • western blot; human; 1:1000; fig 5s1b
Novus Biologicals Itgb3 antibody (Novus, NB600-1342) was used in western blot on human samples at 1:1000 (fig 5s1b). elife (2019) ncbi
Articles Reviewed
  1. Pan R, Yu Y, Zhu H, Zhang W, Qin Y, Ye L, et al. RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation. iScience. 2022;25:105184 pubmed publisher
  2. Wakao S, Oguma Y, Kushida Y, Kuroda Y, Tatsumi K, Dezawa M. Phagocytosing differentiated cell-fragments is a novel mechanism for controlling somatic stem cell differentiation within a short time frame. Cell Mol Life Sci. 2022;79:542 pubmed publisher
  3. Gawish R, Maier B, Obermayer G, Watzenboeck M, Gorki A, Quattrone F, et al. A neutrophil-B-cell axis impacts tissue damage control in a mouse model of intraabdominal bacterial infection via Cxcr4. elife. 2022;11: pubmed publisher
  4. Zheleznyak A, Mixdorf M, Marsala L, Prior J, Yang X, Cui G, et al. Orthogonal targeting of osteoclasts and myeloma cells for radionuclide stimulated dynamic therapy induces multidimensional cell death pathways. Theranostics. 2021;11:7735-7754 pubmed publisher
  5. Hutton C, Heider F, Blanco Gómez A, Banyard A, Kononov A, Zhang X, et al. Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity. Cancer Cell. 2021;: pubmed publisher
  6. Brito V, Patrocinio M, Sousa M, Barreto A, Frasnelli S, Lara V, et al. Mast cells contribute to alveolar bone loss in Spontaneously Hypertensive Rats with periodontal disease regulating cytokines production. PLoS ONE. 2021;16:e0247372 pubmed publisher
  7. Park M, Kim A, Manandhar S, Oh S, Jang G, Kang L, et al. CCN1 interlinks integrin and hippo pathway to autoregulate tip cell activity. elife. 2019;8: pubmed publisher
  8. Menon V, Thomas R, Elgueta C, Horl M, Osborn T, Hallett P, et al. Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. Stem Cells. 2019;37:1293-1306 pubmed publisher
  9. Faralli J, Filla M, Peters D. Effect of αvβ3 Integrin Expression and Activity on Intraocular Pressure. Invest Ophthalmol Vis Sci. 2019;60:1776-1788 pubmed publisher
  10. Li Y, Li K, Hu W, Ojcius D, Fang J, Li S, et al. Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer. elife. 2019;8: pubmed publisher
  11. Chu J, Mccormick B, Mazelyte G, Michael M, Vermeren S. HoxB8 neutrophils replicate Fcγ receptor and integrin-induced neutrophil signaling and functions. J Leukoc Biol. 2019;105:93-100 pubmed publisher
  12. Abe A, Hashimoto K, Akiyama A, Iida M, Ikeda N, Hamano A, et al. αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors. Brain Res. 2018;1691:94-104 pubmed publisher
  13. Harly C, Cam M, Kaye J, Bhandoola A. Development and differentiation of early innate lymphoid progenitors. J Exp Med. 2018;215:249-262 pubmed publisher
  14. Jiang M, Qiu J, Zhang L, Lu D, Long M, Chen L, et al. Changes in tension regulates proliferation and migration of fibroblasts by remodeling expression of ECM proteins. Exp Ther Med. 2016;12:1542-1550 pubmed
  15. Park S, Zheng J, Nguyen V, Jiang S, Kim D, Szardenings M, et al. RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy. Theranostics. 2016;6:1672-82 pubmed publisher
  16. Lee M, Park H, Lee B, Jung J, Yoo J, Kim S. Identification of Angiogenesis Rich-Viable Myocardium using RGD Dimer based SPECT after Myocardial Infarction. Sci Rep. 2016;6:27520 pubmed publisher
  17. Ruhland M, Loza A, Capietto A, Luo X, Knolhoff B, Flanagan K, et al. Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nat Commun. 2016;7:11762 pubmed publisher
  18. Liu S, Zhou F, Shen Y, Zhang Y, Yin H, Zeng Y, et al. Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget. 2016;7:32876-92 pubmed publisher
  19. Cordeiro O, Chypre M, Brouard N, Rauber S, Alloush F, Romera Hernandez M, et al. Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PLoS ONE. 2016;11:e0151848 pubmed publisher
  20. Liu H, Zhang A, Xu J, Chen Y, Zhu Y. H2S protects against fatal myelosuppression by promoting the generation of megakaryocytes/platelets. J Hematol Oncol. 2016;9:13 pubmed publisher
  21. Murakami K, Günesdogan U, Zylicz J, Tang W, Sengupta R, Kobayashi T, et al. NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers. Nature. 2016;529:403-407 pubmed publisher
  22. Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
  23. Fiore V, Strane P, Bryksin A, White E, Hagood J, Barker T. Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction. J Cell Biol. 2015;211:173-90 pubmed publisher
  24. Mori S, Kodaira M, Ito A, Okazaki M, Kawaguchi N, Hamada Y, et al. Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells. PLoS ONE. 2015;10:e0137486 pubmed publisher
  25. Shen Y, Gao M, Ma Y, Yu H, Cui F, Gregersen H, et al. Effect of surface chemistry on the integrin induced pathway in regulating vascular endothelial cells migration. Colloids Surf B Biointerfaces. 2015;126:188-97 pubmed publisher
  26. Inaba J, McConnell E, Davis K. Lunasin sensitivity in non-small cell lung cancer cells is linked to suppression of integrin signaling and changes in histone acetylation. Int J Mol Sci. 2014;15:23705-24 pubmed publisher
  27. Cheshenko N, Trepanier J, González P, Eugenin E, Jacobs W, Herold B. Herpes simplex virus type 2 glycoprotein H interacts with integrin ?v?3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells. J Virol. 2014;88:10026-38 pubmed publisher
  28. Uehara K, Uehara A. Integrin ?v?5 in endothelial cells of rat splenic sinus: an immunohistochemical and ultrastructural study. Cell Tissue Res. 2014;356:183-93 pubmed publisher
  29. Ahn E, Kim Y, Kshitiz -, An S, Afzal J, Lee S, et al. Spatial control of adult stem cell fate using nanotopographic cues. Biomaterials. 2014;35:2401-2410 pubmed publisher
  30. Kuehn C, Lakey J, Lamb M, Vermette P. Young porcine endocrine pancreatic islets cultured in fibrin show improved resistance toward hydrogen peroxide. Islets. 2013;5:207-15 pubmed publisher
  31. Kotake S, Yago T, Kawamoto M, Nanke Y. Voltage-dependent anion channels (VDACs, porin) expressed in the plasma membrane regulate the differentiation and function of human osteoclasts. Cell Biol Int. 2013;37:65-77 pubmed publisher
  32. Maddala R, Chauhan B, Walker C, Zheng Y, Robinson M, Lang R, et al. Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011;360:30-43 pubmed publisher
  33. Bermudez L, Sangari F, Kolonoski P, Petrofsky M, Goodman J. The efficiency of the translocation of Mycobacterium tuberculosis across a bilayer of epithelial and endothelial cells as a model of the alveolar wall is a consequence of transport within mononuclear phagocytes and invasion of alveolar epithelial cel. Infect Immun. 2002;70:140-6 pubmed