This is a Validated Antibody Database (VAD) review about rat Itgav, based on 35 published articles (read how Labome selects the articles), using Itgav antibody in all methods. It is aimed to help Labome visitors find the most suited Itgav antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Itgav synonym: Cd51

Santa Cruz Biotechnology
mouse monoclonal (H-2)
  • western blot; human; loading ...; fig 2c
Santa Cruz Biotechnology Itgav antibody (Santa Cruz, sc-376,156) was used in western blot on human samples (fig 2c). J Exp Clin Cancer Res (2021) ncbi
mouse monoclonal (23C6)
  • immunohistochemistry - paraffin section; rat; loading ...; fig 6f
Santa Cruz Biotechnology Itgav antibody (Santa Cruz, sc-7312) was used in immunohistochemistry - paraffin section on rat samples (fig 6f). PLoS ONE (2021) ncbi
mouse monoclonal (H-2)
  • western blot; human; 1:100; loading ...; fig 5a
Santa Cruz Biotechnology Itgav antibody (SantaCruz, sc-376156) was used in western blot on human samples at 1:100 (fig 5a). Oncotarget (2016) ncbi
mouse monoclonal (23C6)
  • immunocytochemistry; human; fig 3
In order to study inhibition of the FAK/PI3K/Akt/mTOR signaling pathway through av-beta-3 integrin interaction by the anti-tumor NC1 domain of collagen XIX, Santa Cruz Biotechnology Itgav antibody (Santa Cruz, sc7312) was used in immunocytochemistry on human samples (fig 3). Oncotarget (2016) ncbi
mouse monoclonal (H-2)
  • western blot; human; fig 1
Santa Cruz Biotechnology Itgav antibody (santa cruz, sc-376156) was used in western blot on human samples (fig 1). Mol Cell Proteomics (2015) ncbi
mouse monoclonal (H-2)
  • western blot; human
Santa Cruz Biotechnology Itgav antibody (Santa Cruz Biotechnology, sc-376156) was used in western blot on human samples . Colloids Surf B Biointerfaces (2015) ncbi
mouse monoclonal (P1F76)
  • blocking or activating experiments; forest day mosquito
Santa Cruz Biotechnology Itgav antibody (Santa Cruz Biotechnology, SC-13588) was used in blocking or activating experiments on forest day mosquito samples . ScientificWorldJournal (2014) ncbi
mouse monoclonal (23C6)
  • immunoprecipitation; human; 1:200
  • western blot; human; 1:200; fig 1
In order to test if integrin alphavbeta3 signaling promotes the release of intracellular calcium and contributes to viral entry and spread, Santa Cruz Biotechnology Itgav antibody (Santa Cruz Biotechnology, sc7312) was used in immunoprecipitation on human samples at 1:200 and in western blot on human samples at 1:200 (fig 1). J Virol (2014) ncbi
mouse monoclonal (P1F76)
  • western blot; mouse
In order to study the role of the Rac1 GTPase the shaping of the ocular lens, Santa Cruz Biotechnology Itgav antibody (Santa, SC-13588) was used in western blot on mouse samples . Dev Biol (2011) ncbi
mouse monoclonal (23C6)
  • western blot; mouse
In order to study the role of the Rac1 GTPase the shaping of the ocular lens, Santa Cruz Biotechnology Itgav antibody (Santa, SC-7312) was used in western blot on mouse samples . Dev Biol (2011) ncbi
Abcam
mouse monoclonal (10D5)
  • blocking or activating experiments; mouse; loading ...; fig 5f
Abcam Itgav antibody (Abcam, ab77906) was used in blocking or activating experiments on mouse samples (fig 5f). Adv Sci (Weinh) (2022) ncbi
domestic rabbit monoclonal (EPR16800)
  • western blot; human; 1:1000; loading ...; fig 1f
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2b
  • immunocytochemistry; mouse; loading ...; fig 1c
  • western blot; mouse; 1:1000; loading ...; fig 1d
Abcam Itgav antibody (Abcam, ab179475) was used in western blot on human samples at 1:1000 (fig 1f), in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2b), in immunocytochemistry on mouse samples (fig 1c) and in western blot on mouse samples at 1:1000 (fig 1d). Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (EPR16800)
  • immunohistochemistry - paraffin section; pigs ; 1:5000; loading ...; fig 5k
Abcam Itgav antibody (Abcam, ab179475) was used in immunohistochemistry - paraffin section on pigs samples at 1:5000 (fig 5k). Sci Adv (2019) ncbi
domestic rabbit monoclonal (EPR16800)
  • western blot; mouse; loading ...; fig 6a
Abcam Itgav antibody (Abcam, ab179475) was used in western blot on mouse samples (fig 6a). Bone Rep (2019) ncbi
domestic rabbit monoclonal (EPR16800)
  • western blot; human; loading ...; fig s2a
Abcam Itgav antibody (Abcam, EPR16800) was used in western blot on human samples (fig s2a). PLoS Pathog (2018) ncbi
mouse monoclonal (10D5)
  • blocking or activating experiments; human; loading ...; fig 3a,b
Abcam Itgav antibody (Abcam, ab77906) was used in blocking or activating experiments on human samples (fig 3a,b). BMC Cancer (2017) ncbi
domestic rabbit monoclonal (EPR16800)
  • immunohistochemistry; human; fig 6
  • western blot; human; fig 3
In order to investigate how integrins regulate adipose tissue stem cell proliferation and differentiation, Abcam Itgav antibody (Abcam, ab179475) was used in immunohistochemistry on human samples (fig 6) and in western blot on human samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR5583)
  • western blot; human; 1:2000; loading ...; fig s1
In order to study the role of cellular apoptosis susceptibility and integrin beta 1 in tumor cell migration and invasion of hepatocellular carcinoma, Abcam Itgav antibody (Abcam, ab124968) was used in western blot on human samples at 1:2000 (fig s1). Oncotarget (2016) ncbi
domestic rabbit monoclonal (EPR16800)
  • western blot; human; loading ...; fig 3b
Abcam Itgav antibody (Abcam, ab179475) was used in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
BioLegend
mouse monoclonal (P1F6)
  • flow cytometry; human; loading ...; fig 5a
BioLegend Itgav antibody (BioLegend, 920010) was used in flow cytometry on human samples (fig 5a). Cell Rep (2020) ncbi
mouse monoclonal (P1F6)
  • ELISA; human; loading ...; fig 1d
BioLegend Itgav antibody (Southern Biotech, 9200-05) was used in ELISA on human samples (fig 1d). Cell (2019) ncbi
Invitrogen
mouse monoclonal (23C6)
  • immunocytochemistry; human
In order to study voltage-dependent anion channels in human osteoclasts, Invitrogen Itgav antibody (Endogen, 23C6) was used in immunocytochemistry on human samples . Cell Biol Int (2013) ncbi
mouse monoclonal (23C6)
  • blocking or activating experiments; human
In order to investigate translocation of Mycobacterium tuberculosis across the lung, Invitrogen Itgav antibody (Biosource, 23C6) was used in blocking or activating experiments on human samples . Infect Immun (2002) ncbi
Novus Biologicals
domestic rabbit monoclonal (SC56-07)
  • western blot; mouse; 1:1000; loading ...; fig 6
Novus Biologicals Itgav antibody (Novus, NBP2-67557) was used in western blot on mouse samples at 1:1000 (fig 6). J Cell Mol Med (2019) ncbi
R&D Systems
domestic goat polyclonal
  • immunohistochemistry; mouse; loading ...
R&D Systems Itgav antibody (R&D, AF1219) was used in immunohistochemistry on mouse samples . Nat Commun (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3g
Cell Signaling Technology Itgav antibody (Cell Signaling Technology, 4711) was used in western blot on mouse samples at 1:1000 (fig 3g). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4c
Cell Signaling Technology Itgav antibody (Cell Signaling Technology, 4711) was used in western blot on human samples at 1:1000 (fig 4c). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig s5b
In order to research the promotional effect of endoglin on small muscle cell migration and vascular maturation, Cell Signaling Technology Itgav antibody (Cell Signaling, 4711) was used in western blot on human samples at 1:1000 (fig s5b). Arterioscler Thromb Vasc Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig s1
Cell Signaling Technology Itgav antibody (Cell Signaling, 4711s) was used in western blot on mouse samples at 1:1000 (fig s1). Nat Commun (2016) ncbi
BD Biosciences
mouse monoclonal (21/CD51)
  • western blot; human; 1:1000; loading ...; fig 2f
BD Biosciences Itgav antibody (BD Transduction Laboratories, 611012) was used in western blot on human samples at 1:1000 (fig 2f). Commun Biol (2021) ncbi
mouse monoclonal (21/CD51)
  • western blot; human; loading ...; fig 1a
BD Biosciences Itgav antibody (BD Biosciences, 611012) was used in western blot on human samples (fig 1a). J Biol Chem (2019) ncbi
mouse monoclonal (21/CD51)
  • western blot; mouse; 1:500
BD Biosciences Itgav antibody (BD, 611012) was used in western blot on mouse samples at 1:500. Nat Commun (2016) ncbi
mouse monoclonal (21/CD51)
  • western blot; human; 1:5000; loading ...; fig 2b
In order to discuss the relationship between TGF-beta and MYC in basal subtype breast cancers, BD Biosciences Itgav antibody (BD Biosciences, 611012) was used in western blot on human samples at 1:5000 (fig 2b). Cancer Res (2016) ncbi
mouse monoclonal (21/CD51)
  • western blot; human; loading ...; fig 5c
BD Biosciences Itgav antibody (BD Biosciences, 611013) was used in western blot on human samples (fig 5c). elife (2015) ncbi
mouse monoclonal (21/CD51)
  • western blot; mouse; fig 4
BD Biosciences Itgav antibody (BD, 611012) was used in western blot on mouse samples (fig 4). Eur J Neurosci (2012) ncbi
Developmental Studies Hybridoma Bank
mouse monoclonal (P1F6)
  • flow cytometry; human; loading ...; fig 1a
  • immunoprecipitation; human; loading ...; fig 1b
In order to elucidate how syndecan-1 contributes to multiple myeloma, Developmental Studies Hybridoma Bank Itgav antibody (Millipore, P1F6) was used in flow cytometry on human samples (fig 1a) and in immunoprecipitation on human samples (fig 1b). Cancer Res (2016) ncbi
Articles Reviewed
  1. Wang X, Liu S, Yu T, An S, Deng R, Tan X, et al. Inhibition of Integrin αvβ6 Activation of TGF-β Attenuates Tendinopathy. Adv Sci (Weinh). 2022;9:e2104469 pubmed publisher
  2. Ho T, Yeh S, Chen S, Tsao Y. Integrin αv and Vitronectin Prime Macrophage-Related Inflammation and Contribute the Development of Dry Eye Disease. Int J Mol Sci. 2021;22: pubmed publisher
  3. Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, et al. Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression. J Exp Clin Cancer Res. 2021;40:214 pubmed publisher
  4. Tsutsui K, Machida H, Nakagawa A, Ahn K, Morita R, Sekiguchi K, et al. Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions. Nat Commun. 2021;12:2577 pubmed publisher
  5. Kariya Y, Oyama M, Suzuki T, Kariya Y. αvβ3 Integrin induces partial EMT independent of TGF-β signaling. Commun Biol. 2021;4:490 pubmed publisher
  6. Zhen G, Guo Q, Li Y, Wu C, Zhu S, Wang R, et al. Mechanical stress determines the configuration of TGFβ activation in articular cartilage. Nat Commun. 2021;12:1706 pubmed publisher
  7. Brito V, Patrocinio M, Sousa M, Barreto A, Frasnelli S, Lara V, et al. Mast cells contribute to alveolar bone loss in Spontaneously Hypertensive Rats with periodontal disease regulating cytokines production. PLoS ONE. 2021;16:e0247372 pubmed publisher
  8. Wang S, Zhang Q, Tiwari S, Lichinchi G, Yau E, Hui H, et al. Integrin αvβ5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy. Cell Rep. 2020;30:969-983.e4 pubmed publisher
  9. Chen F, Madajewski B, Ma K, Karassawa Zanoni D, Stambuk H, Turker M, et al. Molecular phenotyping and image-guided surgical treatment of melanoma using spectrally distinct ultrasmall core-shell silica nanoparticles. Sci Adv. 2019;5:eaax5208 pubmed publisher
  10. Cammalleri M, Dal Monte M, Locri F, Pecci V, De Rosa M, Pavone V, et al. The urokinase-type plasminogen activator system as drug target in retinitis pigmentosa: New pre-clinical evidence in the rd10 mouse model. J Cell Mol Med. 2019;23:5176-5192 pubmed publisher
  11. Davis C, Jackson K, McElroy A, Halfmann P, Huang J, Chennareddy C, et al. Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection. Cell. 2019;: pubmed publisher
  12. Bergsma A, Ganguly S, Wiegand M, Dick D, Williams B, Miranti C. Regulation of cytoskeleton and adhesion signaling in osteoclasts by tetraspanin CD82. Bone Rep. 2019;10:100196 pubmed publisher
  13. Liu Z, Li C, Kang N, Malhi H, Shah V, Maiers J. Transforming growth factor β (TGFβ) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation. J Biol Chem. 2019;294:3137-3151 pubmed publisher
  14. Zhao Q, Busch B, Jiménez Soto L, Ishikawa Ankerhold H, Massberg S, Terradot L, et al. Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation. PLoS Pathog. 2018;14:e1007359 pubmed publisher
  15. Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed publisher
  16. Tian H, Ketova T, Hardy D, Xu X, Gao X, Zijlstra A, et al. Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading. Arterioscler Thromb Vasc Biol. 2017;37:1115-1126 pubmed publisher
  17. de la Mare J, Jurgens T, Edkins A. Extracellular Hsp90 and TGFβ regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model. BMC Cancer. 2017;17:202 pubmed publisher
  18. Martin K, Pritchett J, Llewellyn J, Mullan A, Athwal V, Dobie R, et al. PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis. Nat Commun. 2016;7:12502 pubmed publisher
  19. Beauvais D, Jung O, Yang Y, Sanderson R, Rapraeger A. Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth. Cancer Res. 2016;76:4981-93 pubmed publisher
  20. Morandi E, Verstappen R, Zwierzina M, Geley S, Pierer G, Ploner C. ITGAV and ITGA5 diversely regulate proliferation and adipogenic differentiation of human adipose derived stem cells. Sci Rep. 2016;6:28889 pubmed publisher
  21. Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed publisher
  22. Cichon M, Moruzzi M, Shqau T, Miller E, Mehner C, Ethier S, et al. MYC Is a Crucial Mediator of TGF?-Induced Invasion in Basal Breast Cancer. Cancer Res. 2016;76:3520-30 pubmed publisher
  23. Liu S, Zhou F, Shen Y, Zhang Y, Yin H, Zeng Y, et al. Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget. 2016;7:32876-92 pubmed publisher
  24. Winkler J, Roessler S, Sticht C, DiGuilio A, Drucker E, Hölzer K, et al. Cellular apoptosis susceptibility (CAS) is linked to integrin ?1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC). Oncotarget. 2016;7:22883-92 pubmed publisher
  25. Al Thawadi H, Abu Kaoud N, Al Farsi H, Hoarau Véchot J, Rafii S, Rafii A, et al. VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells. Oncotarget. 2016;7:5289-305 pubmed publisher
  26. Rys J, DuFort C, Monteiro D, Baird M, Oses Prieto J, Chand S, et al. Discrete spatial organization of TGFβ receptors couples receptor multimerization and signaling to cellular tension. elife. 2015;4:e09300 pubmed publisher
  27. Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
  28. Gago Fuentes R, Fernández Puente P, Megias D, Carpintero Fernández P, Mateos J, Acea B, et al. Proteomic Analysis of Connexin 43 Reveals Novel Interactors Related to Osteoarthritis. Mol Cell Proteomics. 2015;14:1831-45 pubmed publisher
  29. Shen Y, Gao M, Ma Y, Yu H, Cui F, Gregersen H, et al. Effect of surface chemistry on the integrin induced pathway in regulating vascular endothelial cells migration. Colloids Surf B Biointerfaces. 2015;126:188-97 pubmed publisher
  30. Fongsaran C, Phaonakrop N, Roytrakul S, Thepparit C, Kuadkitkan A, Smith D. Voltage dependent anion channel is redistributed during Japanese encephalitis virus infection of insect cells. ScientificWorldJournal. 2014;2014:976015 pubmed publisher
  31. Cheshenko N, Trepanier J, González P, Eugenin E, Jacobs W, Herold B. Herpes simplex virus type 2 glycoprotein H interacts with integrin ?v?3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells. J Virol. 2014;88:10026-38 pubmed publisher
  32. Kotake S, Yago T, Kawamoto M, Nanke Y. Voltage-dependent anion channels (VDACs, porin) expressed in the plasma membrane regulate the differentiation and function of human osteoclasts. Cell Biol Int. 2013;37:65-77 pubmed publisher
  33. McGeachie A, Skrzypiec A, Cingolani L, Letellier M, Pawlak R, Goda Y. ?3 integrin is dispensable for conditioned fear and hebbian forms of plasticity in the hippocampus. Eur J Neurosci. 2012;36:2461-9 pubmed publisher
  34. Maddala R, Chauhan B, Walker C, Zheng Y, Robinson M, Lang R, et al. Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011;360:30-43 pubmed publisher
  35. Bermudez L, Sangari F, Kolonoski P, Petrofsky M, Goodman J. The efficiency of the translocation of Mycobacterium tuberculosis across a bilayer of epithelial and endothelial cells as a model of the alveolar wall is a consequence of transport within mononuclear phagocytes and invasion of alveolar epithelial cel. Infect Immun. 2002;70:140-6 pubmed