This is a Validated Antibody Database (VAD) review about rat Irf7, based on 5 published articles (read how Labome selects the articles), using Irf7 antibody in all methods. It is aimed to help Labome visitors find the most suited Irf7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Irf7 synonym: interferon regulatory factor 7

Abcam
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 6c
  • immunocytochemistry; human; 1:50; loading ...; fig 1d
In order to elucidate how interferon regulatory factors 3 and 7 contribute to immunity to bacterial infections, Abcam Irf7 antibody (Abcam, ab62505) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 6c) and in immunocytochemistry on human samples at 1:50 (fig 1d). Sci Transl Med (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 3a
  • western blot; human; 1:1000; fig 1a
Abcam Irf7 antibody (Abcam, ab62505) was used in western blot on mouse samples (fig 3a) and in western blot on human samples at 1:1000 (fig 1a). Cell Rep (2016) ncbi
rabbit polyclonal
  • chromatin immunoprecipitation; mouse; fig 9
Abcam Irf7 antibody (Abcam, ab62505) was used in chromatin immunoprecipitation on mouse samples (fig 9). PLoS Pathog (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-1)
  • EMSA; mouse; loading ...; fig 4a
In order to elucidate how interferon regulatory factors 3 and 7 contribute to immunity to bacterial infections, Santa Cruz Biotechnology Irf7 antibody (Santa Cruz, sc-74471) was used in EMSA on mouse samples (fig 4a). Sci Transl Med (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig s4h
Cell Signaling Technology Irf7 antibody (Cell Signaling Technology, 5184) was used in western blot on human samples (fig s4h). Nat Med (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology Irf7 antibody (CST, 5184) was used in western blot on human samples (fig 2a). J Transl Med (2014) ncbi
Articles Reviewed
  1. Mathew N, Baumgartner F, Braun L, O Sullivan D, Thomas S, Waterhouse M, et al. Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nat Med. 2018;24:282-291 pubmed publisher
  2. Puthia M, Ambite I, Cafaro C, Butler D, Huang Y, Lutay N, et al. IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections. Sci Transl Med. 2016;8:336ra59 pubmed publisher
  3. Katlinskaya Y, Katlinski K, Yu Q, Ortiz A, Beiting D, Brice A, et al. Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. Cell Rep. 2016;15:171-180 pubmed publisher
  4. Kropp K, Hsieh W, Isern E, Forster T, Krause E, Brune W, et al. A temporal gate for viral enhancers to co-opt Toll-like-receptor transcriptional activation pathways upon acute infection. PLoS Pathog. 2015;11:e1004737 pubmed publisher
  5. Su Y, Cheng T, Chen C, Chang W, Tsai N, Kung C, et al. Investigation of the caspase-dependent mitochondrial apoptotic pathway in mononuclear cells of patients with systemic Lupus erythematosus. J Transl Med. 2014;12:303 pubmed publisher