This is a Validated Antibody Database (VAD) review about rat Irf3, based on 68 published articles (read how Labome selects the articles), using Irf3 antibody in all methods. It is aimed to help Labome visitors find the most suited Irf3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (D-3)
  • western blot knockout validation; human; 1:1000; loading ...; fig 3a
Santa Cruz Biotechnology Irf3 antibody (Santa, sc-376455) was used in western blot knockout validation on human samples at 1:1000 (fig 3a). Viruses (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D83B9)
  • western blot knockout validation; human; fig 3a
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot knockout validation on human samples (fig 3a). MBio (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (SL-12)
  • western blot; human; loading ...; fig 4b
Santa Cruz Biotechnology Irf3 antibody (Santa Cruz, sc-33641) was used in western blot on human samples (fig 4b). Pathol Oncol Res (2022) ncbi
mouse monoclonal (D-3)
  • western blot knockout validation; human; 1:1000; loading ...; fig 3a
Santa Cruz Biotechnology Irf3 antibody (Santa, sc-376455) was used in western blot knockout validation on human samples at 1:1000 (fig 3a). Viruses (2019) ncbi
mouse monoclonal (SL-12)
  • western blot; human; 1:1000; fig s5
Santa Cruz Biotechnology Irf3 antibody (Santa Cruz, sc-33641) was used in western blot on human samples at 1:1000 (fig s5). Nat Commun (2016) ncbi
mouse monoclonal (D-3)
  • immunocytochemistry; mouse; fig 5
In order to study the relationship between aging and neomycin-induced deafness due to expression of NLRX1 in C57BL/6 mice cochlear hair cells, Santa Cruz Biotechnology Irf3 antibody (Santa Cruz, sc-3764552) was used in immunocytochemistry on mouse samples (fig 5). Neurosci Lett (2016) ncbi
mouse monoclonal (D-3)
  • western blot; mouse; fig 2
Santa Cruz Biotechnology Irf3 antibody (Santa Cruz Biotechnology, D-3) was used in western blot on mouse samples (fig 2). Nat Immunol (2016) ncbi
mouse monoclonal (SL-12)
  • western blot; human; 1:2000
Santa Cruz Biotechnology Irf3 antibody (Santa Cruz, Sc-33641) was used in western blot on human samples at 1:2000. J Virol (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:5000; loading ...; fig s8
Abcam Irf3 antibody (Abcam, ab138449) was used in western blot on human samples at 1:5000 (fig s8). Nat Microbiol (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:500; loading ...; fig 1
Abcam Irf3 antibody (Abcam, ab138449) was used in western blot on rat samples at 1:500 (fig 1). Int J Mol Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4c
Abcam Irf3 antibody (Abcam, ab138449) was used in western blot on human samples (fig 4c). J Virol (2017) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 4b, s12a
Invitrogen Irf3 antibody (ThermoFisher, PA5-36775) was used in western blot on mouse samples at 1:500 (fig 4b, s12a). Nat Commun (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D83B9)
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples at 1:1000. Nat Commun (2022) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 3b
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302S) was used in western blot on mouse samples (fig 3b). J Immunother Cancer (2022) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; 1:400; loading ...; fig 4i
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples at 1:400 (fig 4i). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; pigs ; loading ...; fig 1i
Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on pigs samples (fig 1i). PLoS Pathog (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 3c
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on mouse samples (fig 3c) and in western blot on human samples (fig 3a). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology Irf3 antibody (Cell Signalling, 4302) was used in western blot on human samples (fig 1d). Cancers (Basel) (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 5g
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on mouse samples (fig 5g). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 2g
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302S) was used in western blot on mouse samples (fig 2g). Cell Rep (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 5h
Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on mouse samples (fig 5h). J Nutr Biochem (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; 1:2000
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on human samples at 1:2000. Cell Syst (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on human samples at 1:1000. Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 3f
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 3f). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 3h
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302S) was used in western blot on mouse samples (fig 3h). Cancer Res (2021) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on mouse samples at 1:1000 (fig 4a). elife (2020) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 1d, 4b
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302S) was used in western blot on mouse samples (fig 1d, 4b) and in western blot on human samples (fig 1d). J Immunother Cancer (2020) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; 1:1000; fig 4d
Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on mouse samples at 1:1000 (fig 4d). MBio (2020) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; 1:1000; loading ...; fig 2h
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples at 1:1000 (fig 2h). elife (2020) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on human samples (fig 4c). Biomed Pharmacother (2020) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig s4f
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on mouse samples (fig s4f). Science (2019) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 4f
Cell Signaling Technology Irf3 antibody (Cell Signaling Technologies, 4302) was used in western blot on mouse samples (fig 4f). Cell (2019) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 7d
Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in western blot on mouse samples (fig 7d). J Exp Med (2019) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; 1:1000; loading ...; fig 1b
Cell Signaling Technology Irf3 antibody (Cell signaling, 4302) was used in western blot on human samples at 1:1000 (fig 1b). Nature (2019) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; loading ...; fig 5f
Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on human samples (fig 5f). Cell (2019) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 3d). Cell (2019) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot knockout validation; human; fig 3a
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot knockout validation on human samples (fig 3a). MBio (2019) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 2d
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on mouse samples (fig 2d). Nat Immunol (2019) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; 1:1000; loading ...; fig 7a
  • western blot; human; 1:1000; loading ...; fig 5a
Cell Signaling Technology Irf3 antibody (CST, D83B9) was used in western blot on mouse samples at 1:1000 (fig 7a) and in western blot on human samples at 1:1000 (fig 5a). Front Immunol (2018) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 1a
Cell Signaling Technology Irf3 antibody (Biosciences, 4302) was used in western blot on mouse samples (fig 1a). Cell Death Differ (2018) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; 1:1000; loading ...; fig 2d, 2l
  • western blot; mouse; 1:1000; loading ...; fig 1p, 5g, 6f
Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in western blot on human samples at 1:1000 (fig 2d, 2l) and in western blot on mouse samples at 1:1000 (fig 1p, 5g, 6f). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; fig 4d
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on mouse samples (fig 4d). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; loading ...; fig 5f
Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in western blot on human samples (fig 5f). J Immunol (2018) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 2c
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 2c). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 2a, 3a
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 2a, 3a) and in western blot on human samples (fig 2b). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D83B9)
  • immunohistochemistry; human; loading ...; fig 5e
In order to find interferon-gamma inducible factor 16 functions in the cyclic GMP-AMP synthase-stimulator of interferon genes pathway, Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in immunohistochemistry on human samples (fig 5e). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; fig 6
  • western blot; human; fig 6
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 6) and in western blot on human samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • immunocytochemistry; mouse; loading ...; fig 4b
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in immunocytochemistry on mouse samples (fig 4b) and in western blot on mouse samples (fig 4a). Immunology (2017) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; Chinese tree shrew; fig 5d
In order to investigate the evolution of RIG-I-like receptors, Cell Signaling Technology Irf3 antibody (Cell signaling, 4302) was used in western blot on Chinese tree shrew samples (fig 5d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; 1:5000; fig 5
  • immunocytochemistry; mouse; 1:500; fig 3
  • western blot; mouse; 1:5000; fig 5
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on human samples at 1:5000 (fig 5), in immunocytochemistry on mouse samples at 1:500 (fig 3) and in western blot on mouse samples at 1:5000 (fig 5). BMC Biol (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology Irf3 antibody (Cell Signaling, D83B9) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; fig 8
Cell Signaling Technology Irf3 antibody (Cell signaling, 4302S) was used in western blot on mouse samples (fig 8). PLoS Pathog (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig s2a
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig s2a). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; 1:1000; fig s5
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302S) was used in western blot on human samples at 1:1000 (fig s5). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; fig 2a
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples (fig 2a). J Virol (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology Irf3 antibody (Cell signaling, 4302) was used in western blot on mouse samples (fig 4a). elife (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; fig 5
In order to characterize promotion of an effective anti-tumor immune response by enhancing the production of type 1 interferons by 2'-5' oligoadenylate synthetase-like 1 (OASL1) deficiency in mice, Cell Signaling Technology Irf3 antibody (Cell signaling, 4302) was used in western blot on mouse samples (fig 5). Cancer Immunol Immunother (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; fig 3
  • western blot; mouse; fig 3
Cell Signaling Technology Irf3 antibody (Cell Signaling Tech, 4302) was used in western blot on human samples (fig 3) and in western blot on mouse samples (fig 3). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; fig 4
Cell Signaling Technology Irf3 antibody (Cell signaling, 4302S) was used in western blot on human samples (fig 4). Nat Immunol (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; fig s10b
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, D83B9) was used in western blot on human samples (fig s10b). BMC Biotechnol (2016) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; fig 3
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples (fig 3). Proc Natl Acad Sci U S A (2015) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse
In order to study mechanisms that regulate TLR-induced IL-12 expression and the Th1 response, Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on mouse samples . Virol Sin (2015) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; fig 5
  • western blot; mouse; fig 5
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples (fig 5) and in western blot on mouse samples (fig 5). PLoS Pathog (2015) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; fig 1
In order to analyze the antiviral innate immune response due to mitochondrial DNA stress, Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, D83B9) was used in western blot on mouse samples (fig 1). Nature (2015) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, D83B9) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; fig 2
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on human samples (fig 2). Basic Res Cardiol (2014) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; human; 1:1000
Cell Signaling Technology Irf3 antibody (Cell Signaling Technology, 4302) was used in western blot on human samples at 1:1000. PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse; 1:3000
Cell Signaling Technology Irf3 antibody (Cell Signaling, 4302) was used in western blot on mouse samples at 1:3000. J Virol (2014) ncbi
domestic rabbit monoclonal (D83B9)
  • western blot; mouse
Cell Signaling Technology Irf3 antibody (CST, 4302) was used in western blot on mouse samples . Immunity (2012) ncbi
Articles Reviewed
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  2. Ni H, Zhang H, Li L, Huang H, Guo H, Zhang L, et al. T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer. J Immunother Cancer. 2022;10: pubmed publisher
  3. Jiang L, Li D, Wang C, Liao J, Liu J, Wei Q, et al. Decreased Expression of Karyopherin-α 1 is Related to the Malignant Degree of Cervical Cancer and is Critical for the Proliferation of Hela Cells. Pathol Oncol Res. 2022;28:1610518 pubmed publisher
  4. Sun L, Li Y, Misumi I, Gonzalez Lopez O, Hensley L, Cullen J, et al. IRF3-mediated pathogenicity in a murine model of human hepatitis A. PLoS Pathog. 2021;17:e1009960 pubmed publisher
  5. Wang Z, Chen J, Wu X, Ma D, Zhang X, Li R, et al. PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection. PLoS Pathog. 2021;17:e1009940 pubmed publisher
  6. Zhao F, Zheng T, Gong W, Wu J, Xie H, Li W, et al. Extracellular vesicles package dsDNA to aggravate Crohn's disease by activating the STING pathway. Cell Death Dis. 2021;12:815 pubmed publisher
  7. Proctor M, Gonzalez Cruz J, Daignault Mill S, Veitch M, Zeng B, Ehmann A, et al. Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression. Cancers (Basel). 2021;13: pubmed publisher
  8. Liu Q, Wu J, Zhang X, Li X, Wu X, Zhao Y, et al. Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury. Cell Death Dis. 2021;12:673 pubmed publisher
  9. Shen Y, Tang K, Chen D, Hong M, Sun F, Wang S, et al. Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation. Cell Rep. 2021;35:109272 pubmed publisher
  10. Zhang G, Li R, Li W, Yang S, Sun Q, Yin H, et al. Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. J Nutr Biochem. 2021;95:108761 pubmed publisher
  11. Lopacinski A, Sweatt A, Smolko C, Gray Gaillard E, Borgman C, Shah M, et al. Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback. Cell Syst. 2021;12:304-323.e13 pubmed publisher
  12. Guo G, Gao M, Gao X, Zhu B, Huang J, Luo K, et al. SARS-CoV-2 non-structural protein 13 (nsp13) hijacks host deubiquitinase USP13 and counteracts host antiviral immune response. Signal Transduct Target Ther. 2021;6:119 pubmed publisher
  13. Yu Z, Li X, Yang M, Huang J, Fang Q, Jia J, et al. TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO. Signal Transduct Target Ther. 2021;6:90 pubmed publisher
  14. Wang Y, Luo M, Chen Y, Wang Y, Zhang B, Ren Z, et al. ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. Cancer Res. 2021;81:174-186 pubmed publisher
  15. Tao L, Lemoff A, Wang G, Zarek C, Lowe A, Yan N, et al. Reactive oxygen species oxidize STING and suppress interferon production. elife. 2020;9: pubmed publisher
  16. von Roemeling C, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, et al. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun. 2020;11:1508 pubmed publisher
  17. Wang Bishop L, Wehbe M, Shae D, James J, Hacker B, Garland K, et al. Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma. J Immunother Cancer. 2020;8: pubmed publisher
  18. Ma H, Qian W, Bambousková M, Collins P, Porter S, Byrum A, et al. Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response. MBio. 2020;11: pubmed publisher
  19. Weindel C, Bell S, Vail K, West K, Patrick K, Watson R. LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis. elife. 2020;9: pubmed publisher
  20. Lu M, Zhang Z, Xue M, Zhao B, Harder O, Li A, et al. N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I. Nat Microbiol. 2020;5:584-598 pubmed publisher
  21. Cai H, Yan L, Liu N, Xu M, Cai H. IFI16 promotes cervical cancer progression by upregulating PD-L1 in immunomicroenvironment through STING-TBK1-NF-kB pathway. Biomed Pharmacother. 2020;123:109790 pubmed publisher
  22. Liu Y, You Y, Lu Z, Yang J, Li P, Liu L, et al. N6-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science. 2019;365:1171-1176 pubmed publisher
  23. Ergun S, Fernandez D, Weiss T, Li L. STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition. Cell. 2019;: pubmed publisher
  24. von Gamm M, Schaub A, Jones A, Wolf C, Behrens G, Lichti J, et al. Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3. J Exp Med. 2019;: pubmed publisher
  25. Zhao B, Du F, Xu P, Shu C, Sankaran B, Bell S, et al. A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature. 2019;: pubmed publisher
  26. Liu C, Li X, Nan F, Jiang S, Gao X, Guo S, et al. Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity. Cell. 2019;177:865-880.e21 pubmed publisher
  27. Ashley C, Abendroth A, McSharry B, Slobedman B. Interferon-Independent Upregulation of Interferon-Stimulated Genes during Human Cytomegalovirus Infection is Dependent on IRF3 Expression. Viruses. 2019;11: pubmed publisher
  28. Tan Y, Kagan J. Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility. Cell. 2019;: pubmed publisher
  29. Botto S, Abraham J, Mizuno N, Pryke K, Gall B, Landais I, et al. Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AIM2 Inflammasome. MBio. 2019;10: pubmed publisher
  30. Srikanth S, Woo J, Wu B, El Sherbiny Y, Leung J, Chupradit K, et al. The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum. Nat Immunol. 2019;20:152-162 pubmed publisher
  31. Alam M, Yang D, Trivett A, Meyer T, Oppenheim J. HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways. Front Immunol. 2018;9:2982 pubmed publisher
  32. Liu D, Wu H, Wang C, Li Y, Tian H, Siraj S, et al. STING directly activates autophagy to tune the innate immune response. Cell Death Differ. 2018;: pubmed publisher
  33. Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed publisher
  34. Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed publisher
  35. Ahmad R, Al Roub A, Kochumon S, Akther N, Thomas R, Kumari M, et al. The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation. J Immunol. 2018;200:3599-3611 pubmed publisher
  36. Chen X, Tang L, Fu Y, Wang Y, Han Z, Meng J. Paralemmin-3 contributes to lipopolysaccharide-induced inflammatory response and is involved in lipopolysaccharide-Toll-like receptor-4 signaling in alveolar macrophages. Int J Mol Med. 2017;40:1921-1931 pubmed publisher
  37. Kazak L, Chouchani E, Stavrovskaya I, Lu G, Jedrychowski M, Egan D, et al. UCP1 deficiency causes brown fat respiratory chain depletion and sensitizes mitochondria to calcium overload-induced dysfunction. Proc Natl Acad Sci U S A. 2017;114:7981-7986 pubmed publisher
  38. Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed publisher
  39. Jønsson K, Laustsen A, Krapp C, Skipper K, Thavachelvam K, Hotter D, et al. IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP. Nat Commun. 2017;8:14391 pubmed publisher
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