This is a Validated Antibody Database (VAD) review about rat Insr, based on 56 published articles (read how Labome selects the articles), using Insr antibody in all methods. It is aimed to help Labome visitors find the most suited Insr antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (4B8)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a, 2c
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2a, 2c). Nat Commun (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (4B8)
  • western blot knockout validation; mouse; loading ...; fig 1a
Cell Signaling Technology Insr antibody (Cell Signaling, 3025S) was used in western blot knockout validation on mouse samples (fig 1a). Mol Metab (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (4B8)
  • western blot knockout validation; mouse; fig 2
Cell Signaling Technology Insr antibody (Cell signaling, 3025) was used in western blot knockout validation on mouse samples (fig 2). Endocrinology (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (CT-3)
  • western blot; mouse; 1:500; loading ...; fig 5a, s9a
Santa Cruz Biotechnology Insr antibody (Santa Cruz, sc-57342) was used in western blot on mouse samples at 1:500 (fig 5a, s9a). Nat Commun (2022) ncbi
mouse monoclonal (11B6)
  • western blot; mouse; loading ...; fig 8b
In order to show that PTI-125 therapeutically alters filamin A and reverses proteopathy, Santa Cruz Biotechnology Insr antibody (SantaCruz, SC-81465) was used in western blot on mouse samples (fig 8b). Neurobiol Aging (2017) ncbi
mouse monoclonal (46)
  • western blot; Spodoptera litura; fig 3a
Santa Cruz Biotechnology Insr antibody (SantaCruz, sc-135949) was used in western blot on Spodoptera litura samples (fig 3a). Sci Rep (2016) ncbi
mouse monoclonal (29B4)
  • immunohistochemistry; rat; 1:100; fig 2
Santa Cruz Biotechnology Insr antibody (Santa Cruz, sc-09) was used in immunohistochemistry on rat samples at 1:100 (fig 2). Nat Commun (2015) ncbi
mouse monoclonal (CT-3)
  • immunohistochemistry; rat; 1:100; fig 2
Santa Cruz Biotechnology Insr antibody (Santa Cruz, sc-57342) was used in immunohistochemistry on rat samples at 1:100 (fig 2). Nat Commun (2015) ncbi
mouse monoclonal (11B6)
  • western blot; human; loading ...; fig 3b
In order to quantify proteins involved in mitochondrial oxidation and glucose and lipid metabolism in skeletal muscle of trained and untrained middle-aged men, Santa Cruz Biotechnology Insr antibody (Santa Cruz, sc-81465) was used in western blot on human samples (fig 3b). Physiol Res (2016) ncbi
mouse monoclonal (46)
  • western blot; human
Santa Cruz Biotechnology Insr antibody (Santa Cruz Biotechnology, SC-135949) was used in western blot on human samples . J Diabetes (2016) ncbi
mouse monoclonal (29B4)
  • western blot; human; 1:1000
Santa Cruz Biotechnology Insr antibody (Santa Cruz Biotechnology, sc-09) was used in western blot on human samples at 1:1000. Tumour Biol (2015) ncbi
mouse monoclonal (29B4)
  • western blot; African green monkey
Santa Cruz Biotechnology Insr antibody (Santa Cruz Biotechnology, 29B4) was used in western blot on African green monkey samples . J Biol Chem (2002) ncbi
Abcam
domestic rabbit monoclonal (EPR23566-103)
  • western blot; mouse; 1:1000; loading ...; fig s10e
Abcam Insr antibody (Abcam, ab278100) was used in western blot on mouse samples at 1:1000 (fig s10e). Nat Commun (2022) ncbi
mouse monoclonal (C18C4)
  • immunohistochemistry - free floating section; rat; 1:500; loading ...; fig 5a
  • western blot; rat; 1:1000; loading ...; fig 3a
Abcam Insr antibody (Abcam, ab69508) was used in immunohistochemistry - free floating section on rat samples at 1:500 (fig 5a) and in western blot on rat samples at 1:1000 (fig 3a). Aging Cell (2020) ncbi
mouse monoclonal (C18C4)
  • western blot; human; fig 3
In order to utilize a novel targe for type 2 diabetes and regulate the effects of GPR21, Abcam Insr antibody (Abcam, ab69508) was used in western blot on human samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (C18C4)
  • western blot; human; 1:200; loading ...; fig 1b
In order to demonstrate that receptor tyrosine kinase-like orphan receptor 1 is a scaffold for cavin-1 and caveolin-1, Abcam Insr antibody (Abcam, ab69508) was used in western blot on human samples at 1:200 (fig 1b). Nat Commun (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • flow cytometry; human; loading ...; fig s1a
In order to generate and characterize an antibody that is specific for the insulin receptor and evaluate its effect on diabetic pathogenesis, Invitrogen Insr antibody (Invitrogen, 44-809G) was used in flow cytometry on human samples (fig s1a). Diabetes (2017) ncbi
domestic rabbit polyclonal
  • other; human; fig 7
In order to research a novel method of differential ligand activation and phosphatase-mediated deactivation of insulin receptor tyrosine-specific phosphorylation, Invitrogen Insr antibody (Invitrogen, 44-809G) was used in other on human samples (fig 7). Cell Signal (2016) ncbi
domestic rabbit polyclonal
In order to develop an ELISA method to quantitatively measure activated hybrid receptors comprised of Insulin Receptor and the Insulin-like Growth Factor 1 Receptor, Invitrogen Insr antibody (BioSource, 44-809G) was used . Sci Rep (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (4B8)
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology Insr antibody (Cell Signaling, 3025S) was used in western blot on mouse samples at 1:1000 (fig 3a). Diabetologia (2022) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; loading ...; fig 5c
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on mouse samples (fig 5c). iScience (2021) ncbi
domestic rabbit monoclonal (4B8)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a, 2c
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2a, 2c). Nat Commun (2021) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; 1:1000; loading ...
Cell Signaling Technology Insr antibody (Cell Signalling Technology, 3025) was used in western blot on mouse samples at 1:1000. elife (2021) ncbi
mouse monoclonal (L55B10)
  • western blot; mouse; 1:1000; loading ...; fig 4j
Cell Signaling Technology Insr antibody (Cell Signaling, 3020) was used in western blot on mouse samples at 1:1000 (fig 4j). Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; loading ...; fig 2f
Cell Signaling Technology Insr antibody (Cell Signaling Technology, 3025) was used in western blot on mouse samples (fig 2f). Adv Sci (Weinh) (2021) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; loading ...; fig 7e
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on mouse samples (fig 7e). Sci Rep (2021) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; 1:1000; loading ...; fig 1c
Cell Signaling Technology Insr antibody (CST, 3025S) was used in western blot on mouse samples at 1:1000 (fig 1c). Nat Metab (2021) ncbi
domestic rabbit monoclonal (4B8)
  • immunocytochemistry; mouse; 1:1000; fig 4g
Cell Signaling Technology Insr antibody (Cell signaling, 3025) was used in immunocytochemistry on mouse samples at 1:1000 (fig 4g). J Clin Invest (2021) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; 1:1000; loading ...; fig 8b
Cell Signaling Technology Insr antibody (Cell Signalling Technology, CST3025) was used in western blot on mouse samples at 1:1000 (fig 8b). Bone Res (2021) ncbi
domestic rabbit monoclonal (4B8)
  • western blot knockout validation; mouse; loading ...; fig 1a
Cell Signaling Technology Insr antibody (Cell Signaling, 3025S) was used in western blot knockout validation on mouse samples (fig 1a). Mol Metab (2021) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology Insr antibody (Cell Signaling Technology, 3025) was used in western blot on mouse samples (fig 3d). Sci Rep (2020) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; loading ...; fig 1g
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on mouse samples (fig 1g). elife (2020) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; 1:1000; loading ...; fig 4d
Cell Signaling Technology Insr antibody (Cell Signaling, 3025S) was used in western blot on mouse samples at 1:1000 (fig 4d). elife (2020) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; 1:1000; loading ...; fig 5e, 5f, 5g
Cell Signaling Technology Insr antibody (Cell Signaling, 3025S) was used in western blot on mouse samples at 1:1000 (fig 5e, 5f, 5g). elife (2019) ncbi
domestic rabbit monoclonal (4B8)
  • immunoprecipitation; mouse; loading ...; fig s2b
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in immunoprecipitation on mouse samples (fig s2b). Cell (2019) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; human; loading ...; fig 2h
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on human samples (fig 2h). J Appl Physiol (1985) (2019) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; rat; 1:1000; loading ...; fig 4f, 5f
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on rat samples at 1:1000 (fig 4f, 5f). Br J Pharmacol (2019) ncbi
domestic rabbit monoclonal (4B8)
  • other; human; loading ...; fig 4c
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology Insr antibody (Cell Signaling, 3025S) was used in western blot on mouse samples (fig 3a). Biochem Biophys Res Commun (2017) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; pigs ; loading ...; fig 5b
Cell Signaling Technology Insr antibody (Cell Signal, 3025) was used in western blot on pigs samples (fig 5b). Oncotarget (2017) ncbi
mouse monoclonal (L55B10)
  • western blot; mouse; loading ...; fig s7a
In order to report that the Myomixer-Myomaker interaction regulates myofiber formation during muscle development, Cell Signaling Technology Insr antibody (Cell Signaling, 3020) was used in western blot on mouse samples (fig s7a). Science (2017) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; fig s3d
  • western blot; human; fig 1a
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on mouse samples (fig s3d) and in western blot on human samples (fig 1a). Nature (2017) ncbi
domestic rabbit monoclonal (4B8)
  • flow cytometry; mouse; loading ...; fig 5b
In order to determine a physiological role for IL-1beta and insulin in the regulation of both metabolism and immunity, Cell Signaling Technology Insr antibody (Cell Signaling, 3025S) was used in flow cytometry on mouse samples (fig 5b). Nat Immunol (2017) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; human; loading ...; fig 6a
In order to generate and characterize an antibody that is specific for the insulin receptor and evaluate its effect on diabetic pathogenesis, Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on human samples (fig 6a). Diabetes (2017) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; human; loading ...; fig 4a
In order to identify autophagy-inducing phytochemicals, Cell Signaling Technology Insr antibody (Cell Signaling Technology, 3025) was used in western blot on human samples (fig 4a). Autophagy (2017) ncbi
domestic rabbit monoclonal (4B8)
  • western blot knockout validation; mouse; fig 2
Cell Signaling Technology Insr antibody (Cell signaling, 3025) was used in western blot knockout validation on mouse samples (fig 2). Endocrinology (2016) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on mouse samples at 1:1000 (fig 6). Sci Rep (2016) ncbi
mouse monoclonal (L55B10)
  • immunoprecipitation; mouse; fig 3
  • immunocytochemistry; mouse; fig 1
  • western blot; mouse; fig 3
Cell Signaling Technology Insr antibody (Cell Signaling Technology, 3020S) was used in immunoprecipitation on mouse samples (fig 3), in immunocytochemistry on mouse samples (fig 1) and in western blot on mouse samples (fig 3). Mol Metab (2016) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology Insr antibody (Cell signaling, 3025) was used in western blot on mouse samples at 1:1000 (fig 6). Sci Rep (2016) ncbi
mouse monoclonal (L55B10)
  • western blot; human; fig 8
In order to study attenuation of AKT signaling to promote internal ribosome entry site-dependent translation and expression of c-MYC by the human papillomavirus 16 E7 oncoprotein, Cell Signaling Technology Insr antibody (Cell Signaling, 3020) was used in western blot on human samples (fig 8). J Virol (2016) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; rat; fig 6
Cell Signaling Technology Insr antibody (Cell signaling, 3025) was used in western blot on rat samples (fig 6). Mol Metab (2016) ncbi
mouse monoclonal (L55B10)
  • western blot; mouse; 1:1000; fig 3
Cell Signaling Technology Insr antibody (Cell signaling, 3020) was used in western blot on mouse samples at 1:1000 (fig 3). Free Radic Biol Med (2016) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; fig 3
Cell Signaling Technology Insr antibody (Cell Signaling Tech, 3025) was used in western blot on mouse samples (fig 3). Drug Des Devel Ther (2015) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; fig 3E
Cell Signaling Technology Insr antibody (Cell Signaling Technology, 3025) was used in western blot on mouse samples (fig 3E). Sci Rep (2015) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; human; 1:1000
In order to study the insulin/IGF1 signaling pathway in human astrocytes, Cell Signaling Technology Insr antibody (Cell Signalling Technology, 3025) was used in western blot on human samples at 1:1000. Mol Brain (2015) ncbi
mouse monoclonal (L55B10)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology Insr antibody (Cell signaling, L55B10) was used in western blot on human samples (fig 4a). Mar Drugs (2015) ncbi
domestic rabbit monoclonal (4B8)
  • immunohistochemistry; mouse
  • western blot; mouse
Cell Signaling Technology Insr antibody (Cell Signaling Technology, 3025) was used in immunohistochemistry on mouse samples and in western blot on mouse samples . Mol Neurodegener (2015) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; human; fig 5
In order to investigate how loss of RE-1 Silencing Transcription Factor affects breast cancer, Cell Signaling Technology Insr antibody (cell signaling, 3025) was used in western blot on human samples (fig 5). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; human; loading ...; fig 1c
In order to study mechanisms that confer resistance to therapeutic interventions in the insulin-like growth factor receptor pathway, Cell Signaling Technology Insr antibody (cst, 3025) was used in western blot on human samples (fig 1c). Mol Cancer (2015) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; mouse; fig 2
In order to examine the role of prolyl endopeptidase in glucose metabolism and pancreatic function, Cell Signaling Technology Insr antibody (Cell Signaling, 3025) was used in western blot on mouse samples (fig 2). Proc Natl Acad Sci U S A (2014) ncbi
domestic rabbit monoclonal (4B8)
  • western blot; human
Cell Signaling Technology Insr antibody (Cell signaling, 3025) was used in western blot on human samples . Biochem Biophys Res Commun (2014) ncbi
mouse monoclonal (L55B10)
  • western blot; mouse; 1:1000
Cell Signaling Technology Insr antibody (Cell Signaling, 3020S) was used in western blot on mouse samples at 1:1000. J Biol Chem (2014) ncbi
Articles Reviewed
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  37. Strickland S, Vande Pol S. The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC. J Virol. 2016;90:5611-5621 pubmed publisher
  38. de Castro Barbosa T, Ingerslev L, Alm P, Versteyhe S, Massart J, Rasmussen M, et al. High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring. Mol Metab. 2016;5:184-197 pubmed publisher
  39. Yamaguchi T, Lu C, Ida L, Yanagisawa K, Usukura J, Cheng J, et al. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. Nat Commun. 2016;7:10060 pubmed publisher
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  44. Vigelso A, Prats C, Ploug T, Dela F, Helge J. Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men. Physiol Res. 2016;65:293-302 pubmed
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  46. Luo J, Wu N, Jiang B, Wang L, Wang S, Li X, et al. Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzyl)benzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition. Mar Drugs. 2015;13:4452-69 pubmed publisher
  47. Tan X, Xue Y, Ma T, Wang X, Li J, Lan L, et al. Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment. Mol Neurodegener. 2015;10:24 pubmed publisher
  48. Meyer K, Albaugh B, Schoenike B, Roopra A. Type 1 Insulin-Like Growth Factor Receptor/Insulin Receptor Substrate 1 Signaling Confers Pathogenic Activity on Breast Tumor Cells Lacking REST. Mol Cell Biol. 2015;35:2991-3004 pubmed publisher
  49. Min H, Yun H, Lee J, Lee H, Cho J, Jang H, et al. Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer. Mol Cancer. 2015;14:113 pubmed publisher
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