This is a Validated Antibody Database (VAD) review about rat Insig1, based on 2 published articles (read how Labome selects the articles), using Insig1 antibody in all methods. It is aimed to help Labome visitors find the most suited Insig1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Insig1 synonym: insulin-induced gene 1 protein; INSIG-1; growth response protein (CL-6); immediate-early protein CL-6; insulin-induced growth response protein CL-6

Abcam
rabbit polyclonal
  • immunoprecipitation; human; 1:1000; fig 4
  • western blot; human; 1:1000; fig 4
In order to report that PAQR3 regulates cholesterol homeostasis by anchoring Scap/SREBP to the Golgi, Abcam Insig1 antibody (Abcam, ab70784) was used in immunoprecipitation on human samples at 1:1000 (fig 4) and in western blot on human samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
rabbit polyclonal
  • western blot; human
Abcam Insig1 antibody (Abcam, ab70784) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
Articles Reviewed
  1. Xu D, Wang Z, Zhang Y, Jiang W, Pan Y, Song B, et al. PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus. Nat Commun. 2015;6:8100 pubmed publisher
  2. Cai K, Lucki N, Sewer M. Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells. Biochim Biophys Acta. 2014;1841:552-62 pubmed publisher