This is a Validated Antibody Database (VAD) review about rat Ins1, based on 38 published articles (read how Labome selects the articles), using Ins1 antibody in all methods. It is aimed to help Labome visitors find the most suited Ins1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1f
Invitrogen Ins1 antibody (Thermo Fisher, AHB0052) was used in western blot on mouse samples at 1:1000 (fig 1f). EBioMedicine (2022) ncbi
domestic rabbit polyclonal
  • other; zebrafish
Invitrogen Ins1 antibody (Thermo Fisher Scientific, AHB0052) was used in other on zebrafish samples . Front Mol Neurosci (2021) ncbi
mouse monoclonal (ICBTACLS)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 3a
Invitrogen Ins1 antibody (ebioscience, 53-9769-82) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 3a). Theranostics (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1q
Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in immunohistochemistry on mouse samples at 1:500 (fig 1q). Acta Neuropathol Commun (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; fig 3d
Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in immunohistochemistry on mouse samples (fig 3d). Alzheimers Res Ther (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:500; loading ...; fig s5g
Invitrogen Ins1 antibody (ThermoFisher, AHB0052) was used in immunocytochemistry on human samples at 1:500 (fig s5g). Neuron (2019) ncbi
mouse monoclonal (ICBTACLS)
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 1a
Invitrogen Ins1 antibody (eBiosciences, ICBTACLS) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 1a). Diabetes (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s1b
In order to study the involvement of deacetylase HDAC6 in Tau pathology, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in western blot on human samples at 1:1000 (fig s1b). Cell Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5b
In order to explore the role of necrostatin-1 in Alzheimer's disease, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in western blot on mouse samples at 1:1000 (fig 5b). EMBO Mol Med (2017) ncbi
domestic rabbit polyclonal
  • dot blot; mouse; 1:1000; loading ...; fig 3b
In order to demonstrate the protective effects of an oligomer-specific single-chain variable fragment antibody in Parkinson's disease and Huntington's disease mouse models, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in dot blot on mouse samples at 1:1000 (fig 3b). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • dot blot; mouse; loading ...; fig 5c
In order to ask if nuclear depletion of TDP-43 contributes to Alzheimer's disease pathogenesis, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in dot blot on mouse samples (fig 5c). Acta Neuropathol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig s2
In order to study the reduction of lag-times for amyloid-beta (1-40) fiber formation but generates highly fragmented fibers due to methionine oxidation, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in western blot on human samples (fig s2). Biochim Biophys Acta (2016) ncbi
domestic rabbit polyclonal
  • other; human; fig 6
In order to study the regional vulnerability in middle age that increases in the elderly by using redox proteomic profiling of neuroketal-adducted proteins in the human brain, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in other on human samples (fig 6). Free Radic Biol Med (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; fig 2
In order to assess reduction of pyramidal cell excitability due to intracellular solube alpha-synuclein oligomers, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used in immunocytochemistry on mouse samples (fig 2). J Physiol (2016) ncbi
mouse monoclonal (INS05 (2D11-H5))
  • immunohistochemistry - paraffin section; rat; 1:100; loading ...; fig 1d
In order to study the role of all-trans retinoic acid in improving histological changes of the pancreas in diabetic rats, Invitrogen Ins1 antibody (Thermo Fisher Scientific, INS05) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 1d). Anat Rec (Hoboken) (2016) ncbi
domestic rabbit polyclonal
In order to study the retina of Octodon degus for Alzheimer's disease-related protein expression, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used . PLoS ONE (2015) ncbi
domestic rabbit polyclonal
In order to investigate the role of Fbxo2 in regulating NMDAR subunits in the brain, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used . J Neurosci (2015) ncbi
domestic rabbit polyclonal
In order to examine the aggregation and toxicity of melittin and pancreatic polypeptide, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used . PLoS ONE (2015) ncbi
domestic rabbit polyclonal
In order to study neuroinflammation-related gene regulation during normal aging and in sporadic Alzheimer disease in mice, Invitrogen Ins1 antibody (Invitrogen Thermo-Fisher, AHB0052) was used . J Neuropathol Exp Neurol (2015) ncbi
domestic rabbit polyclonal
In order to investigate the link between metabolic and epigenetic deficits on reduced mitochondrial function, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used . ACS Chem Neurosci (2015) ncbi
domestic rabbit polyclonal
In order to test if DT-diaphorase has a protective role in alpha synuclein neurotoxicity, Invitrogen Ins1 antibody (Invitrogen, AHB0052) was used . Toxicol Sci (2015) ncbi
domestic rabbit polyclonal
In order to investigate the relationship between beta-amyloid plaques and microglia, Invitrogen Ins1 antibody (Life Technologies, AHB0052) was used . Nat Commun (2015) ncbi
domestic rabbit polyclonal
In order to assess the effect of carnosic acid on apoptosis induced by Abeta42 or Abeta43 in human neuroblastoma cells, Invitrogen Ins1 antibody (Invitrogen, #AHB0052) was used . Neurosci Res (2015) ncbi
Abcam
mouse monoclonal (K36aC10)
  • immunohistochemistry; mouse; loading ...
  • western blot; mouse; loading ...
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry on mouse samples and in western blot on mouse samples . Nat Commun (2021) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry; mouse; 1:400; loading ...; fig 7h
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry on mouse samples at 1:400 (fig 7h). Front Endocrinol (Lausanne) (2021) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry; mouse; loading ...; fig 3d
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry on mouse samples (fig 3d). Front Endocrinol (Lausanne) (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3b
Abcam Ins1 antibody (Abcam, ab63820) was used in immunohistochemistry - paraffin section on mouse samples (fig 3b). Front Endocrinol (Lausanne) (2020) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig 4a
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig 4a). Cells (2020) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6a
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 6a). Redox Biol (2018) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 3c
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 3c). J Clin Invest (2017) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; African green monkey; 1:1000; loading ...; fig st9
In order to outline the protocols for antibodies used for immunohistochemical studies, Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry - paraffin section on African green monkey samples at 1:1000 (fig st9). J Toxicol Pathol (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 7d
Abcam Ins1 antibody (Abcam, ab63820) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 7d). Dev Biol (2017) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse; fig 4c
Abcam Ins1 antibody (abcam, ab6995) was used in immunohistochemistry - paraffin section on mouse samples (fig 4c). J Biol Chem (2016) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 5h
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry on mouse samples at 1:1000 (fig 5h). PLoS ONE (2016) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; rat; 1:100; fig 4
Abcam Ins1 antibody (ABCAM, ab6995) was used in immunohistochemistry - paraffin section on rat samples at 1:100 (fig 4). J Diabetes Res (2015) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse; 1:1000
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000. PLoS ONE (2014) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1a
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry - paraffin section on mouse samples (fig 1a). Toxicol Pathol (2015) ncbi
mouse monoclonal (K36aC10)
  • immunohistochemistry; human
Abcam Ins1 antibody (Abcam, ab6995) was used in immunohistochemistry on human samples . Diabetes (2014) ncbi
Articles Reviewed
  1. Han X, Wang C, Song L, Wang X, Tang S, Hou T, et al. KIBRA regulates amyloid β metabolism by controlling extracellular vesicles secretion. EBioMedicine. 2022;78:103980 pubmed publisher
  2. Pakdaman Y, Denker E, Austad E, Norton W, Rolfsnes H, Bindoff L, et al. Chip Protein U-Box Domain Truncation Affects Purkinje Neuron Morphology and Leads to Behavioral Changes in Zebrafish. Front Mol Neurosci. 2021;14:723912 pubmed publisher
  3. Zhao M, Lu J, Li S, Wang H, Cao X, Li Q, et al. Berberine is an insulin secretagogue targeting the KCNH6 potassium channel. Nat Commun. 2021;12:5616 pubmed publisher
  4. Tanday N, English A, Lafferty R, Flatt P, Irwin N. Benefits of Sustained Upregulated Unimolecular GLP-1 and CCK Receptor Signalling in Obesity-Diabetes. Front Endocrinol (Lausanne). 2021;12:674704 pubmed publisher
  5. Lafferty R, Tanday N, Moffett R, Reimann F, Gribble F, Flatt P, et al. Positive Effects of NPY1 Receptor Activation on Islet Structure Are Driven by Pancreatic Alpha- and Beta-Cell Transdifferentiation in Diabetic Mice. Front Endocrinol (Lausanne). 2021;12:633625 pubmed publisher
  6. Sheng J, Wang L, Tang P, Wang H, Li J, Xu B, et al. Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression. Theranostics. 2021;11:2845-2859 pubmed publisher
  7. Vandenabeele M, Veys L, Lemmens S, Hadoux X, Gelders G, Masin L, et al. The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research. Acta Neuropathol Commun. 2021;9:6 pubmed publisher
  8. Son G, Yoo S, Kang S, Rasheed A, Jung D, Park H, et al. Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice. Alzheimers Res Ther. 2021;13:4 pubmed publisher
  9. Petrovic I, Pejnovic N, Ljujic B, Pavlovic S, Miletic Kovacevic M, Jeftic I, et al. Overexpression of Galectin 3 in Pancreatic β Cells Amplifies β-Cell Apoptosis and Islet Inflammation in Type-2 Diabetes in Mice. Front Endocrinol (Lausanne). 2020;11:30 pubmed publisher
  10. Pittala S, Levy I, De S, Kumar Pandey S, Melnikov N, Hyman T, et al. The VDAC1-based R-Tf-D-LP4 Peptide as a Potential Treatment for Diabetes Mellitus. Cells. 2020;9: pubmed publisher
  11. Gasset Rosa F, Lu S, Yu H, Chen C, Melamed Z, Guo L, et al. Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death. Neuron. 2019;102:339-357.e7 pubmed publisher
  12. Anquetil F, Mondanelli G, Gonzalez N, Rodríguez Calvo T, Zapardiel Gonzalo J, Krogvold L, et al. Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes. Diabetes. 2018;67:1858-1866 pubmed publisher
  13. Chen M, Zheng J, Liu G, Xu E, Wang J, Fuqua B, et al. Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux. Redox Biol. 2018;17:432-439 pubmed publisher
  14. Tseng J, Xie L, Song S, Xie Y, Allen L, Ajit D, et al. The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. Cell Rep. 2017;20:2169-2183 pubmed publisher
  15. Kuroda M, Muramatsu R, Maedera N, Koyama Y, Hamaguchi M, Fujimura H, et al. Peripherally derived FGF21 promotes remyelination in the central nervous system. J Clin Invest. 2017;127:3496-3509 pubmed publisher
  16. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  17. Zhang Y, Zeng S, Hao Q, Lu H. Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner. Dev Biol. 2017;423:34-45 pubmed publisher
  18. Yang S, Lee D, Shin J, Lee S, Baek S, Kim J, et al. Nec-1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice. EMBO Mol Med. 2017;9:61-77 pubmed publisher
  19. Zha J, Liu X, Zhu J, Liu S, Lu S, Xu P, et al. A scFv antibody targeting common oligomeric epitope has potential for treating several amyloidoses. Sci Rep. 2016;6:36631 pubmed publisher
  20. Laclair K, Donde A, Ling J, Jeong Y, Chhabra R, Martin L, et al. Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model. Acta Neuropathol. 2016;132:859-873 pubmed
  21. Roth Flach R, Danai L, DiStefano M, Kelly M, Menendez L, Jurczyk A, et al. Protein Kinase Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) Promotes Obesity-induced Hyperinsulinemia. J Biol Chem. 2016;291:16221-30 pubmed publisher
  22. Gu M, Viles J. Methionine oxidation reduces lag-times for amyloid-?(1-40) fiber formation but generates highly fragmented fibers. Biochim Biophys Acta. 2016;1864:1260-1269 pubmed publisher
  23. Domínguez M, de Oliveira E, Odena M, Portero M, Pamplona R, Ferrer I. Redox proteomic profiling of neuroketal-adducted proteins in human brain: Regional vulnerability at middle age increases in the elderly. Free Radic Biol Med. 2016;95:1-15 pubmed publisher
  24. Kaufmann T, Harrison P, Richardson M, Pinheiro T, Wall M. Intracellular soluble α-synuclein oligomers reduce pyramidal cell excitability. J Physiol. 2016;594:2751-72 pubmed publisher
  25. Bronsart L, Stokes C, Contag C. Chemiluminescence Imaging of Superoxide Anion Detects Beta-Cell Function and Mass. PLoS ONE. 2016;11:e0146601 pubmed publisher
  26. Eltony S, Elmottaleb N, Gomaa A, Anwar M, el Metwally T. Effect of All-Trans Retinoic Acid on the Pancreas of Streptozotocin-Induced Diabetic Rat. Anat Rec (Hoboken). 2016;299:334-51 pubmed publisher
  27. Du L, Chang L, Ardiles A, Tapia Rojas C, Araya J, Inestrosa N, et al. Alzheimer's Disease-Related Protein Expression in the Retina of Octodon degus. PLoS ONE. 2015;10:e0135499 pubmed publisher
  28. Alán L, Olejár T, Cahová M, Zelenka J, Berkova Z, Smětáková M, et al. Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats. J Diabetes Res. 2015;2015:385395 pubmed publisher
  29. Atkin G, Moore S, Lu Y, Nelson R, Tipper N, Rajpal G, et al. Loss of F-box only protein 2 (Fbxo2) disrupts levels and localization of select NMDA receptor subunits, and promotes aberrant synaptic connectivity. J Neurosci. 2015;35:6165-78 pubmed publisher
  30. Singh P, Ghosh D, Tewari D, Mohite G, Carvalho E, Jha N, et al. Cytotoxic helix-rich oligomer formation by melittin and pancreatic polypeptide. PLoS ONE. 2015;10:e0120346 pubmed publisher
  31. López González I, Schlüter A, Aso E, Garcia Esparcia P, Ansoleaga B, Llorens F, et al. Neuroinflammatory signals in Alzheimer disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species. J Neuropathol Exp Neurol. 2015;74:319-44 pubmed publisher
  32. Mastroeni D, Khdour O, Arce P, Hecht S, Coleman P. Novel antioxidants protect mitochondria from the effects of oligomeric amyloid beta and contribute to the maintenance of epigenome function. ACS Chem Neurosci. 2015;6:588-98 pubmed publisher
  33. Muñoz P, Cardenas S, Huenchuguala S, Briceño A, Couve E, Paris I, et al. DT-Diaphorase Prevents Aminochrome-Induced Alpha-Synuclein Oligomer Formation and Neurotoxicity. Toxicol Sci. 2015;145:37-47 pubmed publisher
  34. Condello C, Yuan P, Schain A, Grutzendler J. Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques. Nat Commun. 2015;6:6176 pubmed publisher
  35. Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, et al. Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells. Neurosci Res. 2015;94:1-9 pubmed publisher
  36. Moffett R, Vasu S, Thorens B, Drucker D, Flatt P. Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy. PLoS ONE. 2014;9:e96863 pubmed publisher
  37. Guo T, Germolec D, Zheng J, Kooistra L, Auttachoat W, Smith M, et al. Genistein protects female nonobese diabetic mice from developing type 1 diabetes when fed a soy- and alfalfa-free diet. Toxicol Pathol. 2015;43:435-48 pubmed publisher
  38. Bogdani M, Johnson P, Potter Perigo S, Nagy N, Day A, Bollyky P, et al. Hyaluronan and hyaluronan-binding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis. Diabetes. 2014;63:2727-43 pubmed publisher