This is a Validated Antibody Database (VAD) review about rat Ikbkg, based on 11 published articles (read how Labome selects the articles), using Ikbkg antibody in all methods. It is aimed to help Labome visitors find the most suited Ikbkg antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ikbkg synonym: Nemo

Knockout validation
Cell Signaling Technology
mouse monoclonal (DA10-12)
  • western blot knockout validation; mouse; 1 ug/ml; fig 1
In order to report that NEMO contributes to RIG-I activation in response to viruses, Cell Signaling Technology Ikbkg antibody (Cell Signaling, DA10-12) was used in western blot knockout validation on mouse samples at 1 ug/ml (fig 1). Nat Immunol (2007) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • flow cytometry; human; loading ...; fig 6b
Santa Cruz Biotechnology Ikbkg antibody (Santa Cruz Biotechnology, F-10) was used in flow cytometry on human samples (fig 6b). Cell Mol Gastroenterol Hepatol (2021) ncbi
mouse monoclonal (F-10)
  • flow cytometry; human; loading ...; fig 6b
Santa Cruz Biotechnology Ikbkg antibody (Santa Cruz Biotechnology, F-10) was used in flow cytometry on human samples (fig 6b). Cell Mol Gastroenterol Hepatol (2021) ncbi
mouse monoclonal (B-3)
  • western blot; human; fig 5
Santa Cruz Biotechnology Ikbkg antibody (Santa Cruz, sc-8032) was used in western blot on human samples (fig 5). Oncotarget (2015) ncbi
mouse monoclonal (B-3)
  • western blot; human
Santa Cruz Biotechnology Ikbkg antibody (Santa Cruz, sc-8032) was used in western blot on human samples . Mol Cell Biol (2013) ncbi
Abcam
domestic rabbit monoclonal (EPR16629)
  • western blot; mouse; 1:5000; fig 7
Abcam Ikbkg antibody (Abcam, ab178872) was used in western blot on mouse samples at 1:5000 (fig 7). Anal Biochem (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s7e
Cell Signaling Technology Ikbkg antibody (Cell Signaling, 2685) was used in western blot on mouse samples (fig s7e). Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3f
Cell Signaling Technology Ikbkg antibody (CST, 2685) was used in western blot on mouse samples (fig 3f). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (DA10-12)
  • western blot; human; loading ...; fig 3d
In order to discover that Tax recruits linear (Met1-linked) ubiquitin chain assembly complex to the IkB kinase complex, Cell Signaling Technology Ikbkg antibody (Cell Signaling, 2695) was used in western blot on human samples (fig 3d). PLoS Pathog (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5b
Cell Signaling Technology Ikbkg antibody (Cell Signaling, 2685) was used in western blot on mouse samples (fig 5b). J Immunol (2016) ncbi
mouse monoclonal (DA10-12)
  • western blot; mouse; 1:1000; fig 2
Cell Signaling Technology Ikbkg antibody (Cell Signaling, 2695) was used in western blot on mouse samples at 1:1000 (fig 2). PLoS ONE (2015) ncbi
mouse monoclonal (DA10-12)
  • western blot; human
Cell Signaling Technology Ikbkg antibody (CST, 2695S) was used in western blot on human samples . Oncotarget (2014) ncbi
mouse monoclonal (DA10-12)
  • western blot knockout validation; mouse; 1 ug/ml; fig 1
In order to report that NEMO contributes to RIG-I activation in response to viruses, Cell Signaling Technology Ikbkg antibody (Cell Signaling, DA10-12) was used in western blot knockout validation on mouse samples at 1 ug/ml (fig 1). Nat Immunol (2007) ncbi
Articles Reviewed
  1. Sun R, Hedl M, Abraham C. TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants. Cell Mol Gastroenterol Hepatol. 2021;11:249-272 pubmed publisher
  2. Yang S, Harding A, Sweeney C, Miao D, Swan G, Zhou C, et al. Control of antiviral innate immune response by protein geranylgeranylation. Sci Adv. 2019;5:eaav7999 pubmed publisher
  3. Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar A, et al. PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP. Proc Natl Acad Sci U S A. 2017;114:11944-11949 pubmed publisher
  4. Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, et al. HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains. PLoS Pathog. 2017;13:e1006162 pubmed publisher
  5. Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed publisher
  6. Maria Z, Campolo A, Lacombe V. Diabetes Alters the Expression and Translocation of the Insulin-Sensitive Glucose Transporters 4 and 8 in the Atria. PLoS ONE. 2015;10:e0146033 pubmed publisher
  7. Spencer N, Yan Z, Cong L, Zhang Y, Engelhardt J, Stanton R. Definitive localization of intracellular proteins: Novel approach using CRISPR-Cas9 genome editing, with glucose 6-phosphate dehydrogenase as a model. Anal Biochem. 2016;494:55-67 pubmed publisher
  8. Pulvino M, Chen L, Oleksyn D, Li J, Compitello G, Rossi R, et al. Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline. Oncotarget. 2015;6:14796-813 pubmed
  9. Zhuang C, Sheng C, Shin W, Wu Y, Li J, Yao J, et al. A novel drug discovery strategy: mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-κB pathways. Oncotarget. 2014;5:10830-9 pubmed
  10. Chan W, Schaffer T, Pomerantz J. A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival. Mol Cell Biol. 2013;33:429-43 pubmed publisher
  11. Zhao T, Yang L, Sun Q, Arguello M, Ballard D, Hiscott J, et al. The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways. Nat Immunol. 2007;8:592-600 pubmed