This is a Validated Antibody Database (VAD) review about rat Ikbke, based on 9 published articles (read how Labome selects the articles), using Ikbke antibody in all methods. It is aimed to help Labome visitors find the most suited Ikbke antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D61F9)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1b
  • immunoprecipitation; mouse; ; loading ...; fig 9
Cell Signaling Technology Ikbke antibody (CST, 3416) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2a), in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1b) and in immunoprecipitation on mouse samples at (fig 9). Oxid Med Cell Longev (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 2h
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4e
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 2d
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology Ikbke antibody (Cell Signaling, 2690) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 2h), in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4e), in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 2d) and in western blot on human samples at 1:1000 (fig 2b). Biomed Pharmacother (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D61F9)
  • western blot knockout validation; mouse; loading ...; fig 2C
Cell Signaling Technology Ikbke antibody (Cell Signaling, 3416) was used in western blot knockout validation on mouse samples (fig 2C). Biochem J (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D61F9)
  • immunohistochemistry; mouse; loading ...; fig 1b
  • western blot; mouse; 1:1000; loading ...; fig 1a
Cell Signaling Technology Ikbke antibody (CST, 3,416) was used in immunohistochemistry on mouse samples (fig 1b) and in western blot on mouse samples at 1:1000 (fig 1a). Front Physiol (2022) ncbi
domestic rabbit monoclonal (D61F9)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 2a
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1b
  • immunoprecipitation; mouse; ; loading ...; fig 9
Cell Signaling Technology Ikbke antibody (CST, 3416) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2a), in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1b) and in immunoprecipitation on mouse samples at (fig 9). Oxid Med Cell Longev (2021) ncbi
domestic rabbit monoclonal (D61F9)
  • western blot; mouse; loading ...; fig 1f
Cell Signaling Technology Ikbke antibody (Cell Signaling, 3416) was used in western blot on mouse samples (fig 1f). Cell (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 2h
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4e
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 2d
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology Ikbke antibody (Cell Signaling, 2690) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 2h), in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4e), in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 2d) and in western blot on human samples at 1:1000 (fig 2b). Biomed Pharmacother (2019) ncbi
domestic rabbit monoclonal (D1B7)
  • western blot; human; 1:1000; loading ...; fig 1a
  • western blot; mouse; 1:1000; loading ...; fig 1b
Cell Signaling Technology Ikbke antibody (Cell Signaling, 8766) was used in western blot on human samples at 1:1000 (fig 1a) and in western blot on mouse samples at 1:1000 (fig 1b). Front Cell Dev Biol (2018) ncbi
domestic rabbit monoclonal (D61F9)
  • western blot; human; loading ...; fig 2b
  • western blot; mouse; fig 3c
Cell Signaling Technology Ikbke antibody (Cell Signaling, 3416) was used in western blot on human samples (fig 2b) and in western blot on mouse samples (fig 3c). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (D61F9)
  • western blot knockout validation; mouse; loading ...; fig 2C
Cell Signaling Technology Ikbke antibody (Cell Signaling, 3416) was used in western blot knockout validation on mouse samples (fig 2C). Biochem J (2017) ncbi
domestic rabbit monoclonal (D1B7)
  • western blot; mouse; loading ...; fig 2A
Cell Signaling Technology Ikbke antibody (Cell Signaling, 8766) was used in western blot on mouse samples (fig 2A). Biochem J (2017) ncbi
domestic rabbit monoclonal (D1B7)
  • western blot; human; fig 4
Cell Signaling Technology Ikbke antibody (Cell signaling, 8766S) was used in western blot on human samples (fig 4). Nat Immunol (2016) ncbi
domestic rabbit monoclonal (D61F9)
  • western blot; mouse
Cell Signaling Technology Ikbke antibody (Cell Signaling Technology, 3416) was used in western blot on mouse samples . PLoS ONE (2013) ncbi
Articles Reviewed
  1. Liu Y, Xu Y, Yao Y, Cao Y, Chen G, Cai Y, et al. I-κB kinase-ε deficiency improves doxorubicin-induced dilated cardiomyopathy by inhibiting the NF-κB pathway. Front Physiol. 2022;13:934899 pubmed publisher
  2. Cao Y, Li L, Liu Y, Chen G, Tao Z, Wang R, et al. I-κB Kinase-ε Deficiency Attenuates the Development of Angiotensin II-Induced Myocardial Hypertrophy in Mice. Oxid Med Cell Longev. 2021;2021:6429197 pubmed publisher
  3. Tan Y, Kagan J. Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility. Cell. 2019;: pubmed publisher
  4. He S, Nian F, Chen W, Yin L, Auchoybur M, Tao Z, et al. I-κB kinase-ε knockout protects against angiotensin II induced aortic valve thickening in apolipoprotein E deficient mice. Biomed Pharmacother. 2019;109:1287-1295 pubmed publisher
  5. Lork M, Kreike M, Staal J, Beyaert R. Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKK?/TBK1 as a Case Study. Front Cell Dev Biol. 2018;6:40 pubmed publisher
  6. Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed publisher
  7. Bakshi S, Taylor J, Strickson S, McCartney T, Cohen P. Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon ?. Biochem J. 2017;474:1163-1174 pubmed publisher
  8. Starokadomskyy P, Gemelli T, Rios J, Xing C, Wang R, Li H, et al. DNA polymerase-? regulates the activation of type I interferons through cytosolic RNA:DNA synthesis. Nat Immunol. 2016;17:495-504 pubmed publisher
  9. Dai J, Shen D, Bian Z, Zhou H, Gan H, Zong J, et al. IKKi deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis. PLoS ONE. 2013;8:e53412 pubmed publisher