This is a Validated Antibody Database (VAD) review about rat Igf2r, based on 32 published articles (read how Labome selects the articles), using Igf2r antibody in all methods. It is aimed to help Labome visitors find the most suited Igf2r antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Igf2r synonym: IGF-IIR; Igfr2; cation-independent mannose-6-phosphate receptor

Abcam
rabbit monoclonal (EPR6599)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 6c
Abcam Igf2r antibody (Abcam, ab124767) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 6c). Hum Mol Genet (2018) ncbi
mouse monoclonal (2G11)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 6c
Abcam Igf2r antibody (Abcam, ab2733) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 6c). Hum Mol Genet (2018) ncbi
mouse monoclonal (2G11)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 7d
Abcam Igf2r antibody (Abcam, ab2733) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 7d). Cancer Res (2018) ncbi
mouse monoclonal (2G11)
  • immunohistochemistry; human; 1:300; loading ...; fig 4a
Abcam Igf2r antibody (Abcam, 2G11) was used in immunohistochemistry on human samples at 1:300 (fig 4a). Nat Commun (2018) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; 1:400; loading ...; fig s5a
Abcam Igf2r antibody (Abcam, ab2733) was used in immunocytochemistry on human samples at 1:400 (fig s5a). Nat Commun (2017) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; loading ...; fig 3b
In order to explore the regulatory mechanisms and consequences of tubule fission failure, Abcam Igf2r antibody (Abcam, ab2733) was used in immunocytochemistry on human samples (fig 3b). J Cell Biol (2017) ncbi
rabbit monoclonal (EPR6599)
  • western blot; human; loading ...; fig 5a
Abcam Igf2r antibody (Abcam, ab124767) was used in western blot on human samples (fig 5a). elife (2017) ncbi
rabbit monoclonal (EPR6599)
  • immunocytochemistry; human; loading ...; fig 5d
  • western blot; human; loading ...; fig 5c
In order to demonstrate that sorting nexin 1 and 2 are cleaved by initiator caspases during apoptosis, Abcam Igf2r antibody (Abcam, ab124767) was used in immunocytochemistry on human samples (fig 5d) and in western blot on human samples (fig 5c). Cell Death Discov (2017) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; 1:100; loading ...; fig 4d
Abcam Igf2r antibody (Abcam, ab2733) was used in immunocytochemistry on human samples at 1:100 (fig 4d). BMC Biol (2017) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; fig 4d1
Abcam Igf2r antibody (Abcam, ab2733) was used in immunocytochemistry on human samples (fig 4d1). Toxins (Basel) (2017) ncbi
rabbit monoclonal (EPR6599)
  • western blot; human; fig 1c
Abcam Igf2r antibody (Abcam, ab124767) was used in western blot on human samples (fig 1c). Hum Mol Genet (2017) ncbi
rabbit monoclonal (EPR6599)
  • immunocytochemistry; rat; loading ...; fig 4e
Abcam Igf2r antibody (Abcam, ab124767) was used in immunocytochemistry on rat samples (fig 4e). Microbiologyopen (2017) ncbi
rabbit monoclonal (EPR6599)
  • immunocytochemistry; human; loading ...; fig s2c
Abcam Igf2r antibody (Abcam, ab124767) was used in immunocytochemistry on human samples (fig s2c). J Cell Biol (2016) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; fig 5
Abcam Igf2r antibody (abcam, ab2733) was used in immunocytochemistry on human samples (fig 5). PLoS ONE (2016) ncbi
mouse monoclonal (2G11)
  • western blot; mouse; fig 3a
In order to research the effects of environmental tobacco smoke on autophagy and longevity, Abcam Igf2r antibody (Abcam, ab2733) was used in western blot on mouse samples (fig 3a). Oncotarget (2016) ncbi
mouse monoclonal (2G11)
  • In-Cell Western; mouse; fig s4
In order to assess the genetic variation of SLC30A2 associated with breast cell dysfunction, Abcam Igf2r antibody (Abcam, ab2733) was used in In-Cell Western on mouse samples (fig s4). J Mammary Gland Biol Neoplasia (2015) ncbi
rabbit monoclonal (EPR6599)
  • western blot; human; fig 3e
Abcam Igf2r antibody (abcam, ab124767) was used in western blot on human samples (fig 3e). J Virol (2015) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; 1:100; fig s5
In order to characterize Kv2.1/Kv6.4/KCNE5 channel complexes, Abcam Igf2r antibody (Abcam, 2G11) was used in immunocytochemistry on human samples at 1:100 (fig s5). Sci Rep (2015) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; fig 8
Abcam Igf2r antibody (Abcam, ab2733) was used in immunocytochemistry on human samples (fig 8). Mol Biol Cell (2015) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; fig s4a
Abcam Igf2r antibody (Abcam, ab2733) was used in immunocytochemistry on human samples (fig s4a). EMBO J (2015) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; 1:200; fig s5
Abcam Igf2r antibody (Abcam, ab2733) was used in immunocytochemistry on human samples at 1:200 (fig s5). Nature (2015) ncbi
mouse monoclonal (2G11)
  • immunohistochemistry - frozen section; human
In order to study the induction of dopaminergic neurodegeneration by VPS35 mutations associated with Parkinson's disease, Abcam Igf2r antibody (Abcam, 2G11) was used in immunohistochemistry - frozen section on human samples . Hum Mol Genet (2014) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; 1:200
  • western blot; human; 1:200
Abcam Igf2r antibody (Abcam, ab2733-100) was used in immunocytochemistry on human samples at 1:200 and in western blot on human samples at 1:200. Traffic (2014) ncbi
mouse monoclonal (2G11)
  • western blot; human; 1:100
Abcam Igf2r antibody (Abcam, ab2733) was used in western blot on human samples at 1:100. Nature (2014) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human
Abcam Igf2r antibody (Abcam, ab2733) was used in immunocytochemistry on human samples . Mol Biol Cell (2013) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; 1:500; fig 4a
Abcam Igf2r antibody (Abcam, Ab2733) was used in immunocytochemistry on human samples at 1:500 (fig 4a). J Biol Chem (2013) ncbi
Invitrogen
mouse monoclonal (2G11)
  • immunocytochemistry; human; loading ...; fig 5d
  • western blot; human; loading ...; fig 5c
In order to demonstrate that sorting nexin 1 and 2 are cleaved by initiator caspases during apoptosis, Invitrogen Igf2r antibody (Thermo Fisher, MA1-066) was used in immunocytochemistry on human samples (fig 5d) and in western blot on human samples (fig 5c). Cell Death Discov (2017) ncbi
mouse monoclonal (2G11)
  • immunohistochemistry; cow; loading ...; fig 4e
In order to investigate the effect of Fasciola hepatica FhTLM on host immune functions, Invitrogen Igf2r antibody (Thermo Fischer Scientific, 2G11) was used in immunohistochemistry on cow samples (fig 4e). PLoS Pathog (2016) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; fig s2
In order to study disruption of ATG9A trafficking and autophagosome closure by excess sphinogomyelin, Invitrogen Igf2r antibody (Thermo Fisher Scientific Pierce, MA1-066) was used in immunocytochemistry on human samples (fig s2). Autophagy (2016) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; 1:100; fig 4
In order to study the nuclear translocation of Atox1, Invitrogen Igf2r antibody (hermo Fisher Scientific, MA1-066) was used in immunocytochemistry on human samples at 1:100 (fig 4). Protein Pept Lett (2015) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; fig 3
In order to assess adeno-associated virus transduction and its requirement for syntaxin 5-dependent retrograde transport to the trans-Golgi network, Invitrogen Igf2r antibody (Cell Signaling Technologies, MAI-066) was used in immunocytochemistry on human samples (fig 3). J Virol (2015) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; fig s1
In order to study the interaction between CCT and LOX-1, Invitrogen Igf2r antibody (Thermo Scientific, MA1-066) was used in immunocytochemistry on human samples (fig s1). FEBS Lett (2014) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; hamsters; fig 6
In order to investigate the fate of incoming matrix protein from VSV during virus uncoating, Invitrogen Igf2r antibody (Affinity BioReagents, MA1-066) was used in immunocytochemistry on hamsters samples (fig 6). PLoS Pathog (2010) ncbi
mouse monoclonal (2G11)
  • immunocytochemistry; human; fig 4
In order to study the molecular motor role of myosin Vc in secretory granule trafficking, Invitrogen Igf2r antibody (Affinity BioReagents, 2G11) was used in immunocytochemistry on human samples (fig 4). Mol Biol Cell (2009) ncbi
Articles Reviewed
  1. Pellegrini L, Hauser D, Li Y, Mamais A, Beilina A, Kumaran R, et al. Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice. Hum Mol Genet. 2018;27:3257-3271 pubmed publisher
  2. Quaranta V, Rainer C, Nielsen S, Raymant M, Ahmed M, Engle D, et al. Macrophage-Derived Granulin Drives Resistance to Immune Checkpoint Inhibition in Metastatic Pancreatic Cancer. Cancer Res. 2018;78:4253-4269 pubmed publisher
  3. Navarro Negredo P, Edgar J, Manna P, Antrobus R, Robinson M. The WDR11 complex facilitates the tethering of AP-1-derived vesicles. Nat Commun. 2018;9:596 pubmed publisher
  4. Bednash J, Weathington N, Londino J, Rojas M, Gulick D, Fort R, et al. Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity. Nat Commun. 2017;8:15203 pubmed publisher
  5. Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed publisher
  6. Elwell C, Czudnochowski N, Von Dollen J, Johnson J, Nakagawa R, Mirrashidi K, et al. Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction. elife. 2017;6: pubmed publisher
  7. Duclos C, Champagne A, Carrier J, Saucier C, Lavoie C, Denault J. Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling. Cell Death Discov. 2017;3:16100 pubmed publisher
  8. Wong M, Gillingham A, Munro S. The golgin coiled-coil proteins capture different types of transport carriers via distinct N-terminal motifs. BMC Biol. 2017;15:3 pubmed publisher
  9. Zimmermann Meisse G, Prevost G, Jover E. Above and beyond C5a Receptor Targeting by Staphylococcal Leucotoxins: Retrograde Transport of Panton-Valentine Leucocidin and ?-Hemolysin. Toxins (Basel). 2017;9: pubmed publisher
  10. Kim M, Deng H, Wong Y, Siddique T, Krainc D. The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking. Hum Mol Genet. 2017;26:729-741 pubmed publisher
  11. Sulaiman A, Zolnierczyk K, Japa O, Owen J, Maddison B, Emes R, et al. A Trematode Parasite Derived Growth Factor Binds and Exerts Influences on Host Immune Functions via Host Cytokine Receptor Complexes. PLoS Pathog. 2016;12:e1005991 pubmed publisher
  12. Rofe A, Davis L, Whittingham J, Latimer Bowman E, Wilkinson A, Pryor P. The Rhodococcus equi virulence protein VapA disrupts endolysosome function and stimulates lysosome biogenesis. Microbiologyopen. 2017;6: pubmed publisher
  13. McMillan K, Gallon M, Jellett A, Clairfeuille T, Tilley F, McGough I, et al. Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins. J Cell Biol. 2016;214:389-99 pubmed publisher
  14. Want A, Gillespie S, Wang Z, Gordon R, Iomini C, Ritch R, et al. Autophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients. PLoS ONE. 2016;11:e0157404 pubmed publisher
  15. Ting W, Yang J, Kuo C, Xiao Z, Lu X, Yeh Y, et al. Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts. Oncotarget. 2016;7:39017-39025 pubmed publisher
  16. Corcelle Termeau E, Vindeløv S, Hämälistö S, Mograbi B, Keldsbo A, Bräsen J, et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy. 2016;12:833-49 pubmed publisher
  17. Alam S, Hennigar S, Gallagher C, Soybel D, Kelleher S. Exome Sequencing of SLC30A2 Identifies Novel Loss- and Gain-of-Function Variants Associated with Breast Cell Dysfunction. J Mammary Gland Biol Neoplasia. 2015;20:159-72 pubmed publisher
  18. Ju X, Yan Y, Liu Q, Li N, Sheng M, Zhang L, et al. Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture. J Virol. 2015;89:10347-58 pubmed publisher
  19. David J, Stas J, Schmitt N, Bocksteins E. Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels. Sci Rep. 2015;5:12813 pubmed publisher
  20. Hirst J, Edgar J, Borner G, Li S, Sahlender D, Antrobus R, et al. Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking. Mol Biol Cell. 2015;26:3085-103 pubmed publisher
  21. Munson M, Allen G, Toth R, Campbell D, Lucocq J, Ganley I. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J. 2015;34:2272-90 pubmed publisher
  22. Kahra D, Mondol T, Niemiec M, Wittung Stafshede P. Human Copper Chaperone Atox1 Translocates to the Nucleus but does not Bind DNA In Vitro. Protein Pept Lett. 2015;22:532-8 pubmed
  23. Renard H, Simunovic M, Lemière J, Boucrot E, Garcia Castillo M, Arumugam S, et al. Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis. Nature. 2015;517:493-6 pubmed publisher
  24. Nonnenmacher M, Cintrat J, Gillet D, Weber T. Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction. J Virol. 2015;89:1673-87 pubmed publisher
  25. Bakthavatsalam D, Soung R, Tweardy D, Chiu W, Dixon R, Woodside D. Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor. FEBS Lett. 2014;588:2133-40 pubmed publisher
  26. Tsika E, Glauser L, Moser R, Fiser A, Daniel G, Sheerin U, et al. Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration. Hum Mol Genet. 2014;23:4621-38 pubmed publisher
  27. Rydell G, Renard H, Garcia Castillo M, Dingli F, Loew D, Lamaze C, et al. Rab12 localizes to Shiga toxin-induced plasma membrane invaginations and controls toxin transport. Traffic. 2014;15:772-87 pubmed publisher
  28. Mancias J, Wang X, Gygi S, Harper J, Kimmelman A. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature. 2014;509:105-9 pubmed publisher
  29. Hirst J, Borner G, Edgar J, Hein M, Mann M, Buchholz F, et al. Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15. Mol Biol Cell. 2013;24:2558-69 pubmed publisher
  30. Snyder J, Rochelle L, Lyerly H, Caron M, BARAK L. Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network. J Biol Chem. 2013;288:10286-97 pubmed publisher
  31. Mire C, White J, Whitt M. A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating. PLoS Pathog. 2010;6:e1000994 pubmed publisher
  32. Jacobs D, Weigert R, Grode K, Donaldson J, Cheney R. Myosin Vc is a molecular motor that functions in secretory granule trafficking. Mol Biol Cell. 2009;20:4471-88 pubmed publisher