This is a Validated Antibody Database (VAD) review about rat Igf1r, based on 59 published articles (read how Labome selects the articles), using Igf1r antibody in all methods. It is aimed to help Labome visitors find the most suited Igf1r antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Igf1r synonym: IGF-1 receptor; IGFIRC; Igfr1; JTK13

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D23H3)
  • western blot knockout validation; human; 1:1000; loading ...; fig 4i, s5n
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot knockout validation on human samples at 1:1000 (fig 4i, s5n). Nat Commun (2021) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig 7f
Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, 3027) was used in western blot knockout validation on mouse samples (fig 7f). Adv Sci (Weinh) (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D23H3)
  • western blot knockout validation; mouse; loading ...; fig 1a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750S) was used in western blot knockout validation on mouse samples (fig 1a). Mol Metab (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D23H3)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1a). PLoS ONE (2019) ncbi
Abcam
domestic rabbit monoclonal (EPR19322)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3d
Abcam Igf1r antibody (Abcam, ab182408) was used in immunohistochemistry - paraffin section on mouse samples (fig 3d). Front Aging Neurosci (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 9a
Abcam Igf1r antibody (Abcam, ab39398) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 9a). Mol Med Rep (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; fig 2b
Abcam Igf1r antibody (Abcam, ab39398) was used in immunohistochemistry on human samples (fig 2b). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EPR19322)
  • immunohistochemistry; mouse; loading ...; fig 2
  • western blot; mouse; loading ...; fig 3
Abcam Igf1r antibody (abcam, ab182408) was used in immunohistochemistry on mouse samples (fig 2) and in western blot on mouse samples (fig 3). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 4a
In order to research the effects of environmental tobacco smoke on autophagy and longevity, Abcam Igf1r antibody (Abcam, ab39675) was used in western blot on mouse samples (fig 4a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 4a
In order to research the effects of environmental tobacco smoke on autophagy and longevity, Abcam Igf1r antibody (Abcam, ab-39398) was used in western blot on mouse samples (fig 4a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; fig s4
In order to determine stromal miR-143/145 microRNAs promote tumorigenesis, Abcam Igf1r antibody (Abcam, ab39398) was used in immunohistochemistry - frozen section on mouse samples (fig s4). Cancer Discov (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-1)
  • western blot; mouse; 1:200; loading ...; fig 1h
Santa Cruz Biotechnology Igf1r antibody (Santa Cruz, sc-390130) was used in western blot on mouse samples at 1:200 (fig 1h). EMBO Mol Med (2020) ncbi
mouse monoclonal (2C8)
  • western blot; mouse; loading ...; fig 3a
Santa Cruz Biotechnology Igf1r antibody (Santa Cruz, sc-463) was used in western blot on mouse samples (fig 3a). Int J Mol Sci (2017) ncbi
mouse monoclonal (3B7)
  • western blot; human; fig 4
Santa Cruz Biotechnology Igf1r antibody (Santa Cruz, sc-462) was used in western blot on human samples (fig 4). Oncol Lett (2015) ncbi
mouse monoclonal (3B7)
  • immunohistochemistry; mouse; 1:400; fig 4
In order to characterize attenuation of dystrophinopathy in humans and mice by translation from a DMD exon 5 IRES that results in a functional dystrophin isoform, Santa Cruz Biotechnology Igf1r antibody (SantaCruz, sc-462) was used in immunohistochemistry on mouse samples at 1:400 (fig 4). Nat Med (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D23H3)
  • western blot; human; 1:1000; fig 2f
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750S) was used in western blot on human samples at 1:1000 (fig 2f). Nature (2022) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; loading ...; fig 2d
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot on human samples (fig 2d). Cell Oncol (Dordr) (2022) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 5a, 5b
  • western blot; mouse; loading ...; fig 5a, 5b
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in immunoprecipitation on mouse samples (fig 5a, 5b) and in western blot on mouse samples (fig 5a, 5b). Acta Neuropathol Commun (2022) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; 1:500; loading ...; fig e8q, e9b
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750S) was used in western blot on human samples at 1:500 (fig e8q, e9b). Nature (2022) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot knockout validation; human; 1:1000; loading ...; fig 4i, s5n
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot knockout validation on human samples at 1:1000 (fig 4i, s5n). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig 7f
Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, 3027) was used in western blot knockout validation on mouse samples (fig 7f). Adv Sci (Weinh) (2021) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot on human samples at 1:1000 (fig 3c). J Immunother Cancer (2021) ncbi
domestic rabbit monoclonal (111A9)
  • western blot; human; 1:1000; loading ...; fig 1a
Cell Signaling Technology Igf1r antibody (cell signalling technology, 3018) was used in western blot on human samples at 1:1000 (fig 1a). Nat Commun (2021) ncbi
domestic rabbit monoclonal (111A9)
  • western blot; human; 1:2500; fig 3a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3018S) was used in western blot on human samples at 1:2500 (fig 3a). Cell Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in western blot on mouse samples at 1:1000 (fig 4a). Cancer Sci (2021) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot knockout validation; mouse; loading ...; fig 1a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750S) was used in western blot knockout validation on mouse samples (fig 1a). Mol Metab (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3i
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in western blot on mouse samples at 1:1000 (fig 3i). Commun Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3i
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3021) was used in western blot on mouse samples at 1:1000 (fig 3i). Commun Biol (2021) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology Igf1r antibody (CST, 9750) was used in western blot on mouse samples (fig 3d). Sci Rep (2020) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; loading ...; fig 5a, 5b
Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, 9750) was used in western blot on human samples (fig 5a, 5b). J Hematol Oncol (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s3h
  • western blot; rat; 1:1000; loading ...; fig 4a
Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, 3027) was used in western blot on mouse samples at 1:1000 (fig s3h) and in western blot on rat samples at 1:1000 (fig 4a). Sci Adv (2020) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, 9750) was used in western blot on human samples (fig 3b). Breast Cancer Res (2019) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1a). PLoS ONE (2019) ncbi
domestic rabbit polyclonal
  • chromatin immunoprecipitation; human; loading ...; fig 2g
  • immunoprecipitation; mouse; loading ...; fig 1c
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in chromatin immunoprecipitation on human samples (fig 2g) and in immunoprecipitation on mouse samples (fig 1c). Cell (2019) ncbi
domestic rabbit monoclonal (111A9)
  • western blot; human; 1:2000; loading ...; fig 7d
Cell Signaling Technology Igf1r antibody (CST, 3018) was used in western blot on human samples at 1:2000 (fig 7d). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s10f
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in western blot on human samples (fig s10f). Nat Med (2018) ncbi
domestic rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2f
Cell Signaling Technology Igf1r antibody (Cell signaling, 6113) was used in western blot on mouse samples (fig 2f). Cancer Res (2017) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; mouse; loading ...; fig 2f
Cell Signaling Technology Igf1r antibody (Cell signaling, 9750) was used in western blot on mouse samples (fig 2f). Cancer Res (2017) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; loading ...; fig 3i
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750S) was used in western blot on human samples (fig 3i). Cell (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 7a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in western blot on mouse samples (fig 7a). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; loading ...; fig 4a
  • western blot; mouse; fig 3a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot on human samples (fig 4a) and in western blot on mouse samples (fig 3a). Sci Signal (2017) ncbi
domestic rabbit monoclonal (111A9)
  • western blot; mouse; loading ...; fig 3a
Cell Signaling Technology Igf1r antibody (Cell signaling, 3018) was used in western blot on mouse samples (fig 3a). Mol Biol Cell (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 1a
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3021) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; hamsters; fig 1b
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot on hamsters samples (fig 1b). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
In order to demonstrate that entinostat targets SALL4-positive lung cancer, Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (C14A11)
  • immunocytochemistry; rat; 1:50; loading ...; fig 1b
In order to provide a mechanistic link between three early polarity events needed for neuronal polarity, Cell Signaling Technology Igf1r antibody (Cell Signaling, C14A11) was used in immunocytochemistry on rat samples at 1:50 (fig 1b). Mol Neurobiol (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...
  • western blot; human; 1:1000; loading ...; fig 5a
In order to delineate the mechanism for lung tumorigenesis by a tobacco-specific carcinogen, Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in immunohistochemistry - paraffin section on human samples and in western blot on human samples at 1:1000 (fig 5a). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in western blot on human samples at 1:1000 (fig 2). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; 1:1000; loading ...; fig 3f
In order to determine if the extracellular matrix components of human skin fibroblasts change under non-stretch, static stretch, or cyclic stretch conditions, Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot on human samples at 1:1000 (fig 3f). Exp Ther Med (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig st1
Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig st1). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4c
Cell Signaling Technology Igf1r antibody (cell signaling, 3027S) was used in western blot on human samples (fig 4c). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse
Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, 3027) was used in immunocytochemistry on mouse samples . Mol Metab (2016) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; 1:1000; fig 3
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, cst-9750) was used in western blot on human samples at 1:1000 (fig 3) and in western blot on mouse samples at 1:1000 (fig 1). Nat Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; fig 1
Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, 3027) was used in immunohistochemistry on mouse samples (fig 1). Neuron (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Igf1r antibody (Cell signaling, 3027) was used in western blot on human samples (fig 4). Mol Cancer (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
In order to study the role of MAML3 in proliferation and retinoic acid-mediated differentiation, Cell Signaling Technology Igf1r antibody (Cell Signaling, 3027) was used in western blot on human samples (fig 5). Mol Cancer Res (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:50; loading ...; fig 1b
In order to demonstrate that receptor tyrosine kinase-like orphan receptor 1 is a scaffold for cavin-1 and caveolin-1, Cell Signaling Technology Igf1r antibody (Cell Signalling, 3027) was used in western blot on human samples at 1:50 (fig 1b). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human
In order to examine the role of asporin in the early stages of eye development in Xenopus embryos, Cell Signaling Technology Igf1r antibody (Cell Signaling Technology, 9750) was used in western blot on human samples . Development (2015) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; mouse; 1:1000; fig 7
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot on mouse samples at 1:1000 (fig 7). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; fig 5
In order to investigate how loss of RE-1 Silencing Transcription Factor affects breast cancer, Cell Signaling Technology Igf1r antibody (cell signaling, 9750) was used in western blot on human samples (fig 5). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (111A9)
  • western blot; human; fig 3
Cell Signaling Technology Igf1r antibody (Cell signaling, 3018) was used in western blot on human samples (fig 3). MAbs (2015) ncbi
domestic rabbit monoclonal (111A9)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Igf1r antibody (Cell Signaling Tech, 3018) was used in western blot on human samples at 1:1000 (fig 2). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D23H3)
  • immunohistochemistry - paraffin section; mouse; 2 ug/ml; fig 4
  • western blot; mouse; 0.2 ug/ml; fig 4
In order to determine the contribution of ESR2 to medulloblastoma growth in vitro and in vivo, Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in immunohistochemistry - paraffin section on mouse samples at 2 ug/ml (fig 4) and in western blot on mouse samples at 0.2 ug/ml (fig 4). Endocrinology (2015) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human; 1:1000
Cell Signaling Technology Igf1r antibody (Cell Signaling, D23H3) was used in western blot on human samples at 1:1000. Front Endocrinol (Lausanne) (2014) ncbi
domestic rabbit monoclonal (D23H3)
  • western blot; human
  • western blot; mouse
Cell Signaling Technology Igf1r antibody (Cell Signaling, 9750) was used in western blot on human samples and in western blot on mouse samples . Invest Ophthalmol Vis Sci (2013) ncbi
Articles Reviewed
  1. Marei H, Tsai W, Kee Y, Ruiz K, He J, Cox C, et al. Antibody targeting of E3 ubiquitin ligases for receptor degradation. Nature. 2022;610:182-189 pubmed publisher
  2. Cyra M, Schulte M, Berthold R, Heinst L, Jansen E, Gr xfc newald I, et al. SS18-SSX drives CREB activation in synovial sarcoma. Cell Oncol (Dordr). 2022;45:399-413 pubmed publisher
  3. Rauskolb S, Andreska T, Fries S, von Collenberg C, Blum R, Monoranu C, et al. Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment. Acta Neuropathol Commun. 2022;10:68 pubmed publisher
  4. Miller L, Tarantini S, Nyúl Tóth Á, Johnston M, Martin T, Bullen E, et al. Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging. Front Aging Neurosci. 2022;14:788296 pubmed publisher
  5. Weiss J, Hunter M, CRUZ N, Baggiolini A, Tagore M, Ma Y, et al. Anatomic position determines oncogenic specificity in melanoma. Nature. 2022;604:354-361 pubmed publisher
  6. Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed publisher
  7. Vichas A, Riley A, Nkinsi N, Kamlapurkar S, Parrish P, Lo A, et al. Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer. Nat Commun. 2021;12:4789 pubmed publisher
  8. Prekovic S, Schuurman K, Mayayo Peralta I, Manjón A, Buijs M, Yavuz S, et al. Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer. Nat Commun. 2021;12:4360 pubmed publisher
  9. Wang W, Lu G, Liu H, Xiong Z, Leung H, Cao R, et al. Pten Regulates Cardiomyocyte Differentiation by Modulating Non-CG Methylation via Dnmt3. Adv Sci (Weinh). 2021;:e2100849 pubmed publisher
  10. Wu Q, Tian A, Li B, Leduc M, Forveille S, Hamley P, et al. IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms. J Immunother Cancer. 2021;9: pubmed publisher
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  12. Musicant A, Parag Sharma K, Gong W, Sengupta M, Chatterjee A, Henry E, et al. CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition. Cell Rep. 2021;34:108768 pubmed publisher
  13. Isomura H, Taguchi A, Kajino T, Asai N, Nakatochi M, Kato S, et al. Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator. Cancer Sci. 2021;: pubmed publisher
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  16. Grundmann S, Schutkowski A, Berger C, Baur A, König B, Stangl G. High-phosphorus diets reduce aortic lesions and cardiomyocyte size and modify lipid metabolism in Ldl receptor knockout mice. Sci Rep. 2020;10:20748 pubmed publisher
  17. Jin Y, Cheng X, Huang X, Ding F, Lee S, Wang F, et al. The role of Hrd1 in ultraviolet (UV) radiation induced photoaging. Aging (Albany NY). 2020;12:21273-21289 pubmed publisher
  18. Zhou X, Chen N, Xu H, Zhou X, Wang J, Fang X, et al. Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma. J Hematol Oncol. 2020;13:77 pubmed publisher
  19. Bi H, Zhang X, Zhang Y, Xie X, Xia Y, Du J, et al. The deubiquitinase UCHL1 regulates cardiac hypertrophy by stabilizing epidermal growth factor receptor. Sci Adv. 2020;6:eaax4826 pubmed publisher
  20. Bella P, Farini A, Banfi S, Parolini D, Tonna N, Meregalli M, et al. Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy. EMBO Mol Med. 2020;12:e11019 pubmed publisher
  21. Hori A, Shimoda M, Naoi Y, Kagara N, Tanei T, Miyake T, et al. Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer. Breast Cancer Res. 2019;21:88 pubmed publisher
  22. Jin J, Ravindran P, Di Meo D, Püschel A. Igf1R/InsR function is required for axon extension and corpus callosum formation. PLoS ONE. 2019;14:e0219362 pubmed publisher
  23. Hancock M, Meyer R, Mistry M, Khetani R, Wagschal A, Shin T, et al. Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression. Cell. 2019;177:722-736.e22 pubmed publisher
  24. Xu H, Xu S, Xie S, Zhang Y, Yang J, Zhang W, et al. MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway. elife. 2019;8: pubmed publisher
  25. Ruess D, Heynen G, Ciecielski K, Ai J, Berninger A, Kabacaoglu D, et al. Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Nat Med. 2018;24:954-960 pubmed publisher
  26. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  27. Akiel M, Guo C, Li X, Rajasekaran D, Mendoza R, Robertson C, et al. IGFBP7 Deletion Promotes Hepatocellular Carcinoma. Cancer Res. 2017;77:4014-4025 pubmed publisher
  28. Tawo R, Pokrzywa W, Kevei E, Akyuz M, Balaji V, Adrian S, et al. The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. Cell. 2017;169:470-482.e13 pubmed publisher
  29. Cai W, Sakaguchi M, Kleinridders A, Gonzalez Del Pino G, Dreyfuss J, O Neill B, et al. Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. Nat Commun. 2017;8:14892 pubmed publisher
  30. Ting W, Huang C, Jiang C, Lin Y, Chung L, Shen C, et al. Treatment with 17?-Estradiol Reduced Body Weight and the Risk of Cardiovascular Disease in a High-Fat Diet-Induced Animal Model of Obesity. Int J Mol Sci. 2017;18: pubmed publisher
  31. CAROMILE L, Dortche K, Rahman M, Grant C, Stoddard C, Ferrer F, et al. PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer. Sci Signal. 2017;10: pubmed publisher
  32. Chaudhari A, Gupta R, Patel S, Velingkaar N, Kondratov R. Cryptochromes regulate IGF-1 production and signaling through control of JAK2-dependent STAT5B phosphorylation. Mol Biol Cell. 2017;28:834-842 pubmed publisher
  33. Björner S, Rosendahl A, Simonsson M, Markkula A, Jirström K, Borgquist S, et al. Combined and individual tumor-specific expression of insulin-like growth factor-I receptor, insulin receptor and phospho-insulin-like growth factor-I receptor/insulin receptor in primary breast cancer: Implications for prognosis in different treatmen. Oncotarget. 2017;8:9093-9107 pubmed publisher
  34. Han C, Juncadella I, Kinchen J, Buckley M, Klibanov A, Dryden K, et al. Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation. Nature. 2016;539:570-574 pubmed publisher
  35. Yong K, Li A, Ou W, Hong C, Zhao W, Wang F, et al. Targeting SALL4 by entinostat in lung cancer. Oncotarget. 2016;7:75425-75440 pubmed publisher
  36. Oksdath M, Guil A, Grassi D, Sosa L, Quiroga S. The Motor KIF5C Links the Requirements of Stable Microtubules and IGF-1 Receptor Membrane Insertion for Neuronal Polarization. Mol Neurobiol. 2017;54:6085-6096 pubmed publisher
  37. Boo H, Min H, Jang H, Yun H, Smith J, Jin Q, et al. The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells. Nat Commun. 2016;7:12961 pubmed publisher
  38. Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed publisher
  39. Jiang M, Qiu J, Zhang L, Lu D, Long M, Chen L, et al. Changes in tension regulates proliferation and migration of fibroblasts by remodeling expression of ECM proteins. Exp Ther Med. 2016;12:1542-1550 pubmed
  40. Huber M, Falkenberg N, Hauck S, Priller M, Braselmann H, Feuchtinger A, et al. Cyr61 and YB-1 are novel interacting partners of uPAR and elevate the malignancy of triple-negative breast cancer. Oncotarget. 2016;7:44062-44075 pubmed publisher
  41. Svalina M, Kikuchi K, Abraham J, Lal S, Davare M, Settelmeyer T, et al. IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma. Sci Rep. 2016;6:27012 pubmed publisher
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