This is a Validated Antibody Database (VAD) review about rat Hmgb1, based on 39 published articles (read how Labome selects the articles), using Hmgb1 antibody in all methods. It is aimed to help Labome visitors find the most suited Hmgb1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Hmgb1 synonym: Ac2-008; Hmg1

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:4000; loading ...; fig 1a
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot knockout validation on mouse samples at 1:4000 (fig 1a). Med Oncol (2022) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s5f
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples (fig s5f). Nat Commun (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; fig 2d
  • western blot; mouse; 1:1000; fig 2b
Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry on mouse samples (fig 2d) and in western blot on mouse samples at 1:1000 (fig 2b). Exp Ther Med (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1 ug/ml; loading ...; fig 6a
Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry on mouse samples at 1 ug/ml (fig 6a). Int J Mol Sci (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6b
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples at 1:1000 (fig 6b). Front Pharmacol (2022) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:4000; loading ...; fig 1a
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot knockout validation on mouse samples at 1:4000 (fig 1a). Med Oncol (2022) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 4a
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on rat samples at 1:1000 (fig 4a). Pulm Circ (2021) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; fig 2b
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on rat samples at 1:1000 (fig 2b). Mol Med Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 2a
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on rat samples at 1:1000 (fig 2a). Sci Rep (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 6i
Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 6i). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3c
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples (fig 3c). PLoS ONE (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3c
Abcam Hmgb1 antibody (Abcam, AB18256) was used in western blot on mouse samples (fig 3c). elife (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:800; loading ...; fig 1a
Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry on mouse samples at 1:800 (fig 1a). Front Immunol (2020) ncbi
domestic rabbit polyclonal
  • western blot; domestic rabbit; 1:1000; loading ...; fig 3b
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on domestic rabbit samples at 1:1000 (fig 3b). Eur J Med Res (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4a
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples (fig 4a). Oral Dis (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3c
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on human samples at 1:1000 (fig 3c). Cancer Gene Ther (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 7b
Abcam Hmgb1 antibody (Abcam, 18256) was used in western blot on mouse samples (fig 7b). JCI Insight (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 3
Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 3). Asian J Androl (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 3c
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on human samples at 1:500 (fig 3c). J Transl Med (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5b
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on human samples (fig 5b). Nat Commun (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1a
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples (fig 1a). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1d
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples (fig 1d). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig 3
  • western blot; rat; 1:1000; loading ...; fig 4a
In order to investigate the role of RAGE signaling in chronic intermittent hypoxia-induced renal injury, Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry - paraffin section on rat samples at 1:1000 (fig 3) and in western blot on rat samples at 1:1000 (fig 4a). Oxid Med Cell Longev (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - free floating section; rat; 1:100; fig 7
  • western blot; rat; 1:500; fig 7
Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry - free floating section on rat samples at 1:100 (fig 7) and in western blot on rat samples at 1:500 (fig 7). J Neuroinflammation (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s12
In order to study the localization and transport of viral ribonucleoprotein, Abcam Hmgb1 antibody (abcam, ab18256) was used in western blot on human samples (fig s12). Nat Microbiol (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s9
In order to describe a role for HMGB1 in Alzheimer's disease pathogenesis, Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s9). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; human; 1:100; fig s1d
  • immunocytochemistry; human; 1:100; loading ...; fig s1d
Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry - frozen section on human samples at 1:100 (fig s1d) and in immunocytochemistry on human samples at 1:100 (fig s1d). Nature (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - free floating section; rat; 1:100; fig 2
In order to facilitate LIM kinase 2-mediated programmed necrotic neuronal death by mitochondrial translocation of high mobility group box 1, Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunohistochemistry - free floating section on rat samples at 1:100 (fig 2). Front Cell Neurosci (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1 ug/ml; fig 10
Abcam Hmgb1 antibody (Abcam, ab18256) was used in immunocytochemistry on human samples at 1 ug/ml (fig 10). Part Fibre Toxicol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig s1h
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples at 1:2000 (fig s1h). Autophagy (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 7
Abcam Hmgb1 antibody (abcam, ab18256) was used in western blot on human samples at 1:1000 (fig 7). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples (fig 6). Int J Mol Med (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 3
Abcam Hmgb1 antibody (Abcam, ab18256) was used in western blot on mouse samples (fig 3). PLoS ONE (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4
Invitrogen Hmgb1 antibody (Thermo Fisher Scientific, PA5-22722) was used in immunocytochemistry on human samples (fig 4). Molecules (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4
Invitrogen Hmgb1 antibody (Thermo Fisher Scientific, PA5-22722) was used in immunocytochemistry on human samples (fig 4). Front Cell Dev Biol (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5c
Invitrogen Hmgb1 antibody (Thermo Fisher, PA1-16926) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 5c). Nat Commun (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 4 ug/ml; fig 2a
In order to analyze immunogenic biomarkers and immune cells infiltrarion and prognosis in metastasis., Invitrogen Hmgb1 antibody (ThermoScientist, PA1-16926) was used in immunohistochemistry - paraffin section on human samples at 4 ug/ml (fig 2a). Oncoimmunology (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 1
In order to assess the correlation with the immune infiltration in breast cancer due to the presence of HMGB1and LC3B puncta expression in malignant cells, Invitrogen Hmgb1 antibody (Thermo Fisher Scientific/Pierce, PA1-16926) was used in immunohistochemistry - paraffin section on human samples (fig 1). Autophagy (2016) ncbi
domestic rabbit polyclonal
In order to predict residual risk of relapse after adjuvant chemotherapy in breast cancer by combined evaluation of HMGB1 and LC3B puncta, Invitrogen Hmgb1 antibody (ThermoFisher Scientific, PA1-16926) was used . Autophagy (2015) ncbi
domestic rabbit polyclonal
In order to examine the immune responses in patients with esophageal carcinomas treated by neo-adjuvant radiochemotherapy, Invitrogen Hmgb1 antibody (ThermoScientist Pierce, PA1-16926) was used . Oncotarget (2015) ncbi
Articles Reviewed
  1. Moore T, Cheng L, Wolf D, Ngo J, Segawa M, Zhu X, et al. Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes. Nat Commun. 2022;13:6661 pubmed publisher
  2. Bai C, Jiang Z, Jiang H, Yu S, Li M, Chu F, et al. Ac2‑26 alleviates hepatic ischemia‑reperfusion injury based on inhibiting the positive feedback loop of HMGB1/TLR4/NF‑κB/neutrophils. Exp Ther Med. 2022;24:673 pubmed publisher
  3. Stancic A, Velickovic K, Markelic M, Grigorov I, Saksida T, Savić N, et al. Involvement of Ferroptosis in Diabetes-Induced Liver Pathology. Int J Mol Sci. 2022;23: pubmed publisher
  4. Hong J, Zhang M, He Y, Jin Y, He Q, Zhang Y, et al. Qinghao-Biejia Herb Pair Alleviates Pristane-Induced Lupus-Like Disease and Associated Renal and Aortic Lesions in ApoE-/- Mice. Front Pharmacol. 2022;13:897669 pubmed publisher
  5. Yokomizo K, Waki K, Ozawa M, Yamamoto K, Ogasawara S, Yano H, et al. Knockout of high-mobility group box 1 in B16F10 melanoma cells induced host immunity-mediated suppression of in vivo tumor growth. Med Oncol. 2022;39:58 pubmed publisher
  6. Li Y, Li Y, Li L, Yin M, Wang J, Li X. PKR deficiency alleviates pulmonary hypertension via inducing inflammasome adaptor ASC inactivation. Pulm Circ. 2021;11:20458940211046156 pubmed publisher
  7. Zhao Y, Li W, Zhang D. Gycyrrhizic acid alleviates atherosclerotic lesions in rats with diabetes mellitus. Mol Med Rep. 2021;24: pubmed publisher
  8. Oh H, Choi A, Seo N, Lim J, You J, Chung Y. Protective effect of glycyrrhizin, a direct HMGB1 inhibitor, on post-contrast acute kidney injury. Sci Rep. 2021;11:15625 pubmed publisher
  9. Ecker V, Stumpf M, Brandmeier L, Neumayer T, Pfeuffer L, Engleitner T, et al. Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia. Nat Commun. 2021;12:3526 pubmed publisher
  10. Pham T, Liao R, Labaer J, Guo J. Multiplexed In Situ Protein Profiling with High-Performance Cleavable Fluorescent Tyramide. Molecules. 2021;26: pubmed publisher
  11. Liao R, Mondal M, Nazaroff C, Mastroeni D, Coleman P, Labaer J, et al. Highly Sensitive and Multiplexed Protein Imaging With Cleavable Fluorescent Tyramide Reveals Human Neuronal Heterogeneity. Front Cell Dev Biol. 2020;8:614624 pubmed publisher
  12. Jubair L, Lam A, Fallaha S, McMillan N. CRISPR/Cas9-loaded stealth liposomes effectively cleared established HPV16-driven tumours in syngeneic mice. PLoS ONE. 2021;16:e0223288 pubmed publisher
  13. Panic V, Pearson S, Banks J, Tippetts T, Velasco Silva J, Lee S, et al. Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis. elife. 2020;9: pubmed publisher
  14. Ferrara M, Chialli G, Ferreira L, Ruggieri E, Careccia G, Preti A, et al. Oxidation of HMGB1 Is a Dynamically Regulated Process in Physiological and Pathological Conditions. Front Immunol. 2020;11:1122 pubmed publisher
  15. Qian B, Huang H, Cheng M, Qin T, Chen T, Zhao J. Mechanism of HMGB1-RAGE in Kawasaki disease with coronary artery injury. Eur J Med Res. 2020;25:8 pubmed publisher
  16. Wang G, Xu J, Zhao J, Yin W, Liu D, Chen W, et al. Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice. Nat Commun. 2020;11:220 pubmed publisher
  17. Choi S, Shin S, Lee H, Sohn K, Yoon S, Kim J. 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates chemoradiation-induced oral mucositis. Oral Dis. 2020;26:111-121 pubmed publisher
  18. Chaurasiya S, Chen N, Lu J, Martin N, Shen Y, Kim S, et al. A chimeric poxvirus with J2R (thymidine kinase) deletion shows safety and anti-tumor activity in lung cancer models. Cancer Gene Ther. 2019;: pubmed publisher
  19. Kurundkar D, Kurundkar A, Bone N, Becker E, Liu W, Chacko B, et al. SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury. JCI Insight. 2019;4: pubmed publisher
  20. Fan Y, Yang L, Wei Q, Ding Y, Tang Z, Tan P, et al. Toll-like receptor 10 (TLR10) exhibits suppressive effects on inflammation of prostate epithelial cells. Asian J Androl. 2019;21:393-399 pubmed publisher
  21. O Leary M, Choi A, Kim S, Chaurasiya S, Lu J, Park A, et al. Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibits abscopal effect at a single low dose. J Transl Med. 2018;16:110 pubmed publisher
  22. Chu L, Indramohan M, Ratsimandresy R, Gangopadhyay A, Morris E, Monack D, et al. The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. Nat Commun. 2018;9:996 pubmed publisher
  23. Rong X, Wang B, Palladino E, de Aguiar Vallim T, Ford D, Tontonoz P. ER phospholipid composition modulates lipogenesis during feeding and in obesity. J Clin Invest. 2017;127:3640-3651 pubmed publisher
  24. Wang J, Rajbhandari P, Damianov A, Han A, Sallam T, Waki H, et al. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest. 2017;127:987-1004 pubmed publisher
  25. Wu X, Gu W, Lu H, Liu C, Yu B, Xu H, et al. Soluble Receptor for Advanced Glycation End Product Ameliorates Chronic Intermittent Hypoxia Induced Renal Injury, Inflammation, and Apoptosis via P38/JNK Signaling Pathways. Oxid Med Cell Longev. 2016;2016:1015390 pubmed
  26. Xiong X, Gu L, Wang Y, Luo Y, Zhang H, Lee J, et al. Glycyrrhizin protects against focal cerebral ischemia via inhibition of T cell activity and HMGB1-mediated mechanisms. J Neuroinflammation. 2016;13:241 pubmed publisher
  27. Ando T, Yamayoshi S, Tomita Y, Watanabe S, Watanabe T, Kawaoka Y. The host protein CLUH participates in the subnuclear transport of influenza virus ribonucleoprotein complexes. Nat Microbiol. 2016;1:16062 pubmed publisher
  28. Fujita K, Motoki K, Tagawa K, Chen X, Hama H, Nakajima K, et al. HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. Sci Rep. 2016;6:31895 pubmed publisher
  29. Ladoire S, Senovilla L, Enot D, Ghiringhelli F, Poirier Colame V, Chaba K, et al. Biomarkers of immunogenic stress in metastases from melanoma patients: Correlations with the immune infiltrate. Oncoimmunology. 2016;5:e1160193 pubmed publisher
  30. Kojima Y, Volkmer J, McKenna K, Civelek M, Lusis A, Miller C, et al. CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis. Nature. 2016;536:86-90 pubmed
  31. Hyun H, Ko A, Kang T. Mitochondrial Translocation of High Mobility Group Box 1 Facilitates LIM Kinase 2-Mediated Programmed Necrotic Neuronal Death. Front Cell Neurosci. 2016;10:99 pubmed publisher
  32. Hiraku Y, Guo F, Ma N, Yamada T, Wang S, Kawanishi S, et al. Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation. Part Fibre Toxicol. 2016;13:16 pubmed publisher
  33. Ladoire S, Enot D, Senovilla L, Ghiringhelli F, Poirier Colame V, Chaba K, et al. The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer. Autophagy. 2016;12:864-75 pubmed publisher
  34. Son S, Cha M, Choi H, Kang S, Choi H, Lee M, et al. Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease. Autophagy. 2016;12:784-800 pubmed publisher
  35. Gdynia G, Sauer S, Kopitz J, Fuchs D, Duglova K, Ruppert T, et al. The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Commun. 2016;7:10764 pubmed publisher
  36. Zhao H, Hao S, Xu H, Ma L, Zhang Z, Ni Y, et al. Protective role of nuclear factor erythroid 2-related factor 2 in the hemorrhagic shock-induced inflammatory response. Int J Mol Med. 2016;37:1014-22 pubmed publisher
  37. Lai C, Wang K, Lee F, Tsai H, Ma C, Cheng T, et al. Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm. PLoS ONE. 2016;11:e0146565 pubmed publisher
  38. Ladoire S, Penault Llorca F, Senovilla L, Dalban C, Enot D, Locher C, et al. Combined evaluation of LC3B puncta and HMGB1 expression predicts residual risk of relapse after adjuvant chemotherapy in breast cancer. Autophagy. 2015;11:1878-90 pubmed publisher
  39. Vacchelli E, Semeraro M, Enot D, Chaba K, Poirier Colame V, Dartigues P, et al. Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy. Oncotarget. 2015;6:20840-50 pubmed