This is a Validated Antibody Database (VAD) review about rat Hdac4, based on 22 published articles (read how Labome selects the articles), using Hdac4 antibody in all methods. It is aimed to help Labome visitors find the most suited Hdac4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D15C3)
  • western blot knockout validation; mouse; 1:2000; loading ...; fig 2a
Cell Signaling Technology Hdac4 antibody (Cell Signaling, 7628) was used in western blot knockout validation on mouse samples at 1:2000 (fig 2a). Front Physiol (2022) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 2b
Abcam Hdac4 antibody (Abcam, ab12172) was used in western blot on human samples at 1:500 (fig 2b). Nat Commun (2022) ncbi
mouse monoclonal (HDAC-144)
  • western blot; rat; 1:1000; loading ...
Abcam Hdac4 antibody (Abcam, ab12171) was used in western blot on rat samples at 1:1000. Signal Transduct Target Ther (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2d
Abcam Hdac4 antibody (Abcam, ab12172) was used in western blot on human samples at 1:1000 (fig 2d). Nat Commun (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3e
Abcam Hdac4 antibody (Abcam, ab12172) was used in western blot on human samples at 1:1000 (fig 3e). Aging (Albany NY) (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-4)
  • immunocytochemistry; human; loading ...; fig s7d
Santa Cruz Biotechnology Hdac4 antibody (Santa Cruz, sc-46672) was used in immunocytochemistry on human samples (fig s7d). Sci Adv (2019) ncbi
mouse monoclonal (A-4)
  • western blot; mouse; 0.2 ug/ml; fig 2
Santa Cruz Biotechnology Hdac4 antibody (santa Cruz, sc-46672) was used in western blot on mouse samples at 0.2 ug/ml (fig 2). PLoS ONE (2016) ncbi
mouse monoclonal (A-4)
  • immunohistochemistry - paraffin section; human; 1:200; fig 1
Santa Cruz Biotechnology Hdac4 antibody (santa Cruz, sc-46672) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1). BMC Gastroenterol (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D15C3)
  • western blot knockout validation; mouse; 1:2000; loading ...; fig 2a
Cell Signaling Technology Hdac4 antibody (Cell Signaling, 7628) was used in western blot knockout validation on mouse samples at 1:2000 (fig 2a). Front Physiol (2022) ncbi
mouse monoclonal (4A3)
  • western blot; mouse; 1:1000; loading ...; fig 6a
Cell Signaling Technology Hdac4 antibody (Cell Signaling Technolog, 5392) was used in western blot on mouse samples at 1:1000 (fig 6a). Front Cell Dev Biol (2021) ncbi
domestic rabbit monoclonal (D15C3)
  • western blot; mouse; 1:1500; loading ...; fig 4a
Cell Signaling Technology Hdac4 antibody (Cell Signaling Technology, 7628) was used in western blot on mouse samples at 1:1500 (fig 4a). elife (2021) ncbi
mouse monoclonal (4A3)
  • western blot; mouse; 1:1000; loading ...; fig 5g
Cell Signaling Technology Hdac4 antibody (CST, 5392) was used in western blot on mouse samples at 1:1000 (fig 5g). Circulation (2021) ncbi
domestic rabbit monoclonal (D15C3)
  • western blot; human; loading ...; fig 7e
Cell Signaling Technology Hdac4 antibody (Cell Signaling Technology, 7628) was used in western blot on human samples (fig 7e). PLoS ONE (2019) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 7e
Cell Signaling Technology Hdac4 antibody (Cell Signaling, 3424) was used in western blot on rat samples at 1:1000 (fig 7e). J Biol Chem (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 6a
  • chromatin immunoprecipitation; mouse; loading ...; fig 6b
  • western blot; mouse; loading ...; fig s8c
Cell Signaling Technology Hdac4 antibody (Cell signaling, 2072) was used in immunohistochemistry - paraffin section on mouse samples (fig 6a), in chromatin immunoprecipitation on mouse samples (fig 6b) and in western blot on mouse samples (fig s8c). PLoS Genet (2016) ncbi
domestic rabbit monoclonal (D15C3)
  • western blot; human; fig 7
Cell Signaling Technology Hdac4 antibody (Cell signaling, 7628) was used in western blot on human samples (fig 7). Oncogenesis (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 8b
Cell Signaling Technology Hdac4 antibody (Cell Signaling, 2072) was used in western blot on rat samples (fig 8b). Mol Neurobiol (2016) ncbi
mouse monoclonal (4A3)
  • western blot; mouse; 1:1000; fig 3a
In order to determine role of CaMKIIdelta in cardiac progenitor cells, Cell Signaling Technology Hdac4 antibody (Cell Signaling, 5392) was used in western blot on mouse samples at 1:1000 (fig 3a). J Biol Chem (2015) ncbi
mouse monoclonal (4A3)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5a
  • western blot; mouse
Cell Signaling Technology Hdac4 antibody (cell signaling, 5392) was used in immunohistochemistry - frozen section on mouse samples (fig 5a) and in western blot on mouse samples . PLoS ONE (2015) ncbi
mouse monoclonal (4A3)
  • western blot; mouse; 1:1000; fig 7
Cell Signaling Technology Hdac4 antibody (Cell Signaling, 5392) was used in western blot on mouse samples at 1:1000 (fig 7). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (D15C3)
  • western blot; mouse; 1:2000
Cell Signaling Technology Hdac4 antibody (Cell Signaling, 7628) was used in western blot on mouse samples at 1:2000. Cell Death Dis (2013) ncbi
mouse monoclonal (4A3)
  • western blot; mouse; 1:1000
Cell Signaling Technology Hdac4 antibody (Cell Signaling, 5392) was used in western blot on mouse samples at 1:1000. Am J Physiol Heart Circ Physiol (2013) ncbi
mouse monoclonal (4A3)
  • western blot; human; 1:3000
Cell Signaling Technology Hdac4 antibody (Cell Signaling, 5392) was used in western blot on human samples at 1:3000. Exp Hematol (2012) ncbi
Articles Reviewed
  1. Wedge M, Jennings V, Crupi M, Poutou J, Jamieson T, Pelin A, et al. Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy. Nat Commun. 2022;13:1898 pubmed publisher
  2. Ha N, Sun J, Bian Q, Wu D, Wang X. Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development. Front Physiol. 2022;13:819619 pubmed publisher
  3. Zhong G, Zhao D, Li J, Liu Z, Pan J, Yuan X, et al. WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity. Front Cell Dev Biol. 2021;9:739944 pubmed publisher
  4. Guo Y, Yu Z, Wu J, Gong H, Kesteven S, Iismaa S, et al. The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy. elife. 2021;10: pubmed publisher
  5. Zhao D, Zhong G, Li J, Pan J, Zhao Y, Song H, et al. Targeting E3 Ubiquitin-Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination. Circulation. 2021;: pubmed publisher
  6. Xu S, Tao H, Cao W, Cao L, Lin Y, Zhao S, et al. Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. Signal Transduct Target Ther. 2021;6:54 pubmed publisher
  7. Sato T, Verma S, Andrade C, Omeara M, Campbell N, Wang J, et al. A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction. Nat Commun. 2020;11:3282 pubmed publisher
  8. Sonntag T, Moresco J, Yates J, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. PLoS ONE. 2019;14:e0225727 pubmed publisher
  9. Kuznetsov J, Agüero T, Owens D, Kurtenbach S, Field M, Durante M, et al. BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Sci Adv. 2019;5:eaax1738 pubmed publisher
  10. Chang J, Ni Y, Han L, Sinnett Smith J, Jacamo R, Rey O, et al. Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization. J Biol Chem. 2017;292:9523-9539 pubmed publisher
  11. Wang W, Song B, Anbarchian T, Shirazyan A, Sadik J, Lyons K. Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet. 2016;12:e1006352 pubmed publisher
  12. Zeng L, Yang X, Wen Y, Mail S, Wang M, Zhang M, et al. Overexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinoma. Aging (Albany NY). 2016;8:1236-49 pubmed publisher
  13. Chen C, Wei X, Lv Z, Sun X, Wang S, Zhang Y, et al. Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling. PLoS ONE. 2016;11:e0154951 pubmed publisher
  14. Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher
  15. Giaginis C, Damaskos C, Koutsounas I, Zizi Serbetzoglou A, Tsoukalas N, Patsouris E, et al. Histone deacetylase (HDAC)-1, -2, -4 and -6 expression in human pancreatic adenocarcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients' survival. BMC Gastroenterol. 2015;15:148 pubmed publisher
  16. Smith C, D Mello S. Cell and Context-Dependent Effects of the Heat Shock Protein DNAJB6 on Neuronal Survival. Mol Neurobiol. 2016;53:5628-39 pubmed publisher
  17. Quijada P, Hariharan N, Cubillo J, Bala K, Emathinger J, Wang B, et al. Nuclear Calcium/Calmodulin-dependent Protein Kinase II Signaling Enhances Cardiac Progenitor Cell Survival and Cardiac Lineage Commitment. J Biol Chem. 2015;290:25411-26 pubmed publisher
  18. Huang Y, Tiao M, Huang L, Chuang J, Kuo K, Yang Y, et al. Activation of Mir-29a in Activated Hepatic Stellate Cells Modulates Its Profibrogenic Phenotype through Inhibition of Histone Deacetylases 4. PLoS ONE. 2015;10:e0136453 pubmed publisher
  19. Tontonoz P, Cortez Toledo O, Wroblewski K, Hong C, Lim L, Carranza R, et al. The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice. Mol Cell Biol. 2015;35:1125-38 pubmed publisher
  20. Huang S, Scruggs A, Donaghy J, Horowitz J, Zaslona Z, Przybranowski S, et al. Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts. Cell Death Dis. 2013;4:e621 pubmed publisher
  21. Medford H, Porter K, Marsh S. Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2013;305:H114-23 pubmed publisher
  22. Valdez B, Nieto Y, Murray D, Li Y, Wang G, Champlin R, et al. Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. Exp Hematol. 2012;40:800-10 pubmed publisher