This is a Validated Antibody Database (VAD) review about rat Grb2, based on 28 published articles (read how Labome selects the articles), using Grb2 antibody in all methods. It is aimed to help Labome visitors find the most suited Grb2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Grb2 synonym: Ash-psi

Abcam
domestic rabbit monoclonal (Y301)
  • western blot; human; loading ...; fig 5f
Abcam Grb2 antibody (Abcam, ab32111) was used in western blot on human samples (fig 5f). Aging (Albany NY) (2021) ncbi
domestic rabbit monoclonal (Y301)
  • western blot; mouse; 1:2000
Abcam Grb2 antibody (Abcam, ab32111) was used in western blot on mouse samples at 1:2000. Acta Neuropathol (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-7)
  • western blot; human; loading ...; fig 5c
Santa Cruz Biotechnology Grb2 antibody (Santa Cruz Biotechnology, sc-8034) was used in western blot on human samples (fig 5c). Breast Cancer Res (2019) ncbi
mouse monoclonal (E-1)
  • western blot; rat; loading ...
Santa Cruz Biotechnology Grb2 antibody (Santa Cruz, sc-17813) was used in western blot on rat samples . Front Neurosci (2016) ncbi
mouse monoclonal (C-7)
  • western blot; human; 1:200; fig 2
In order to study CD133+ subpopulations in pancreatic cancer, Santa Cruz Biotechnology Grb2 antibody (Santa Cruz, sc-8034) was used in western blot on human samples at 1:200 (fig 2). Oncol Lett (2016) ncbi
mouse monoclonal (1-68)
  • immunoprecipitation; human; fig 2g
  • immunocytochemistry; human; 1:500; fig s3h
  • western blot; human; 1:1000; fig 5a
Santa Cruz Biotechnology Grb2 antibody (Santa Cruz Biotechnology, sc-503) was used in immunoprecipitation on human samples (fig 2g), in immunocytochemistry on human samples at 1:500 (fig s3h) and in western blot on human samples at 1:1000 (fig 5a). Nat Commun (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s6a
Cell Signaling Technology Grb2 antibody (Cell Signaling, 3972) was used in western blot on mouse samples (fig s6a). J Clin Invest (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4c
Cell Signaling Technology Grb2 antibody (Cell Signaling, 3972) was used in western blot on human samples (fig 4c). Cancer Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2a
In order to elucidate the role of SCIMP in Toll-like receptor signaling, Cell Signaling Technology Grb2 antibody (Cell Signaling, 3972) was used in western blot on mouse samples at 1:1000 (fig 2a). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 8
Cell Signaling Technology Grb2 antibody (Cell Signaling Technology, 3972S) was used in western blot on human samples (fig 8). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 5
Cell Signaling Technology Grb2 antibody (Cell Signaling, 3972) was used in western blot on mouse samples (fig 5). Front Cell Neurosci (2016) ncbi
BD Biosciences
mouse monoclonal (81/GRB2)
  • western blot; human; 1:2000; loading ...; fig s3-1f
BD Biosciences Grb2 antibody (BD Transduction Laboratories, 610112) was used in western blot on human samples at 1:2000 (fig s3-1f). elife (2021) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; 1:2000; loading ...; fig s3-1f
BD Biosciences Grb2 antibody (BD Transduction Laboratories, 610112) was used in western blot on human samples at 1:2000 (fig s3-1f). elife (2021) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; 1:1000; loading ...; fig 3b
BD Biosciences Grb2 antibody (BD, 610111s) was used in western blot on human samples at 1:1000 (fig 3b). elife (2021) ncbi
mouse monoclonal (81/GRB2)
  • western blot; mouse; 1:1000; fig 7g
  • western blot; human; 1:1000; fig 7g
BD Biosciences Grb2 antibody (BD, 610112) was used in western blot on mouse samples at 1:1000 (fig 7g) and in western blot on human samples at 1:1000 (fig 7g). J Immunother Cancer (2021) ncbi
mouse monoclonal (81/GRB2)
  • western blot; rat; loading ...; fig 2d
BD Biosciences Grb2 antibody (BD Bioscences, 610111) was used in western blot on rat samples (fig 2d). Cell (2019) ncbi
mouse monoclonal (81/GRB2)
  • immunocytochemistry; human; fig s12
In order to develop a new multiplex dSTORM imaging strategy to localize epitopes on activated T-cells, BD Biosciences Grb2 antibody (BD Biosciences, 610112) was used in immunocytochemistry on human samples (fig s12). Mol Biol Cell (2016) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; loading ...; fig 6b
In order to establish an integrated multilayered proteomics approach to study receptor signaling, BD Biosciences Grb2 antibody (BD Biosciences, 610111) was used in western blot on human samples (fig 6b). Nat Struct Mol Biol (2016) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human
BD Biosciences Grb2 antibody (Transduction Lab, 610111) was used in western blot on human samples . Sci Rep (2016) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; fig 4
In order to determine how sensitivity is restored in resistant ovarian cancer cells by targeting the Ras-MAPK pathway by miR-634, BD Biosciences Grb2 antibody (BD Pharmingen, 610111) was used in western blot on human samples (fig 4). Mol Cancer (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; fig 2
  • western blot; mouse; fig 1
BD Biosciences Grb2 antibody (BD Bioscience, 610111) was used in western blot on human samples (fig 2) and in western blot on mouse samples (fig 1). Nat Med (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; 1:1000; fig 2
BD Biosciences Grb2 antibody (BD Transduction Laboratories, 610112) was used in western blot on human samples at 1:1000 (fig 2). Oncotarget (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; fig 3
BD Biosciences Grb2 antibody (BD Biosciences, 610112) was used in western blot on human samples (fig 3). Nat Commun (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; mouse; fig 2
BD Biosciences Grb2 antibody (BD Bioscience, 610112) was used in western blot on mouse samples (fig 2). Cancer Res (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; fig 4
BD Biosciences Grb2 antibody (BD Transduction, 610112) was used in western blot on human samples (fig 4). J Cell Sci (2015) ncbi
mouse monoclonal (81/GRB2)
  • western blot; mouse; 1:1000; fig 5D
BD Biosciences Grb2 antibody (BD, 610112) was used in western blot on mouse samples at 1:1000 (fig 5D). DNA Repair (Amst) (2015) ncbi
mouse monoclonal (81/GRB2)
  • immunoprecipitation; mouse; fig 7
  • western blot; mouse; 1:2000; fig 7
BD Biosciences Grb2 antibody (BD Transduction Laboratories, 610112) was used in immunoprecipitation on mouse samples (fig 7) and in western blot on mouse samples at 1:2000 (fig 7). PLoS ONE (2014) ncbi
mouse monoclonal (81/GRB2)
  • western blot; human; 1:2000
BD Biosciences Grb2 antibody (BD Biosciences, 610111) was used in western blot on human samples at 1:2000. FEBS Lett (2013) ncbi
Articles Reviewed
  1. Zhang Y, Ding L, Ni Q, Tao R, Qin J. Transcription factor PAX4 facilitates gastric cancer progression through interacting with miR-27b-3p/Grb2 axis. Aging (Albany NY). 2021;13:16786-16803 pubmed publisher
  2. Vemulapalli V, Chylek L, Erickson A, Pfeiffer A, Gabriel K, LaRochelle J, et al. Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling. elife. 2021;10: pubmed publisher
  3. Willoughby P, Allen M, Yu J, Korytnikov R, Chen T, Liu Y, et al. The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium. elife. 2021;10: pubmed publisher
  4. Alghanem A, Abello J, Maurer J, Kumar A, Ta C, Gunasekar S, et al. The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function. elife. 2021;10: pubmed publisher
  5. Ghonim M, Ibba S, Tarhuni A, Errami Y, Luu H, Dean M, et al. Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer. J Immunother Cancer. 2021;9: pubmed publisher
  6. Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed publisher
  7. Kuriakose J, Redecke V, Guy C, Zhou J, Wu R, Ippagunta S, et al. Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis. J Clin Invest. 2019;129:2251-2265 pubmed publisher
  8. Kennedy S, Han J, Portman N, Nobis M, Hastings J, Murphy K, et al. Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer. Breast Cancer Res. 2019;21:43 pubmed publisher
  9. Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed publisher
  10. Luo L, Bokil N, Wall A, Kapetanovic R, Lansdaal N, Marceline F, et al. SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nat Commun. 2017;8:14133 pubmed publisher
  11. Pandini G, Satriano C, Pietropaolo A, Gianì F, Travaglia A, La Mendola D, et al. The Inorganic Side of NGF: Copper(II) and Zinc(II) Affect the NGF Mimicking Signaling of the N-Terminus Peptides Encompassing the Recognition Domain of TrkA Receptor. Front Neurosci. 2016;10:569 pubmed publisher
  12. Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
  13. Sousa A, Rei M, Freitas R, Ricardo S, Caffrey T, David L, et al. Effect of MUC1/?-catenin interaction on the tumorigenic capacity of pancreatic CD133+ cells. Oncol Lett. 2016;12:1811-1817 pubmed
  14. Liu L, Phua Y, Lee R, Ma X, Jenkins Y, Novy K, et al. Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases. J Biol Chem. 2016;291:21571-21583 pubmed
  15. Francavilla C, Papetti M, Rigbolt K, Pedersen A, Sigurdsson J, Cazzamali G, et al. Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking. Nat Struct Mol Biol. 2016;23:608-18 pubmed publisher
  16. Osinalde N, Sánchez Quiles V, Blagoev B, Kratchmarova I. Changes in Gab2 phosphorylation and interaction partners in response to interleukin (IL)-2 stimulation in T-lymphocytes. Sci Rep. 2016;6:23530 pubmed publisher
  17. Zhang X, Peng D, Xi Y, Yuan C, Sagum C, Klein B, et al. G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression. Nat Commun. 2016;7:10810 pubmed publisher
  18. Balakrishnan S, Niebert M, Richter D. Rescue of Cyclic AMP Mediated Long Term Potentiation Impairment in the Hippocampus of Mecp2 Knockout (Mecp2(-/y) ) Mice by Rolipram. Front Cell Neurosci. 2016;10:15 pubmed publisher
  19. van Jaarsveld M, van Kuijk P, Boersma A, Helleman J, Van Ijcken W, Mathijssen R, et al. miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway. Mol Cancer. 2015;14:196 pubmed publisher
  20. Wen Q, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider R, et al. Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition. Nat Med. 2015;21:1473-80 pubmed publisher
  21. Xing M, Wang X, Palmai Pallag T, Shen H, Helleday T, Hickson I, et al. Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget. 2015;6:37638-46 pubmed publisher
  22. Capuani F, Conte A, Argenzio E, Marchetti L, Priami C, Polo S, et al. Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells. Nat Commun. 2015;6:7999 pubmed publisher
  23. Kratochvill F, Gratz N, Qualls J, Van De Velde L, Chi H, Kovarik P, et al. Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner. Cancer Res. 2015;75:3054-64 pubmed publisher
  24. Parodi B, Rossi S, Morando S, Cordano C, Bragoni A, Motta C, et al. Fumarates modulate microglia activation through a novel HCAR2 signaling pathway and rescue synaptic dysregulation in inflamed CNS. Acta Neuropathol. 2015;130:279-95 pubmed publisher
  25. Diesenberg K, Beerbaum M, Fink U, Schmieder P, Krauss M. SEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR. J Cell Sci. 2015;128:397-407 pubmed publisher
  26. Uringa E, Baldeyron C, Odijk H, Wassenaar E, van Cappellen W, Maas A, et al. A mRad51-GFP antimorphic allele affects homologous recombination and DNA damage sensitivity. DNA Repair (Amst). 2015;25:27-40 pubmed publisher
  27. Tao W, Moore R, Smith E, Xu X. Hormonal induction and roles of Disabled-2 in lactation and involution. PLoS ONE. 2014;9:e110737 pubmed publisher
  28. Kodigepalli K, Dutta P, Bauckman K, Nanjundan M. SnoN/SkiL expression is modulated via arsenic trioxide-induced activation of the PI3K/AKT pathway in ovarian cancer cells. FEBS Lett. 2013;587:5-16 pubmed publisher