This is a Validated Antibody Database (VAD) review about rat Gga3, based on 35 published articles (read how Labome selects the articles), using Gga3 antibody in all methods. It is aimed to help Labome visitors find the most suited Gga3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cell Signaling Technology
domestic rabbit monoclonal (D66F1)
  • western blot; mouse; fig 6e
In order to study the effect of bisecting N-acetylglucosamine on beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) activity, Cell Signaling Technology Gga3 antibody (Cell Signaling Technology, 8027) was used in western blot on mouse samples (fig 6e). EMBO Mol Med (2015) ncbi
BD Biosciences
mouse monoclonal (88/Adaptin)
  • western blot; mouse; 1:1000; loading ...; fig 4g, 9a
BD Biosciences Gga3 antibody (BD Transduction, 610385) was used in western blot on mouse samples at 1:1000 (fig 4g, 9a). Nat Commun (2022) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; mouse; loading ...; fig 1b, s1g
BD Biosciences Gga3 antibody (BD Biosciences, 610502) was used in western blot on mouse samples (fig 1b, s1g). Sci Adv (2022) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; mouse; 1:2000; loading ...; fig 2n, s3k
BD Biosciences Gga3 antibody (BD Biosciences, 610385) was used in western blot on mouse samples at 1:2000 (fig 2n, s3k). Int J Mol Sci (2021) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; rat; loading ...
BD Biosciences Gga3 antibody (BD Biosciences, 610385) was used in immunocytochemistry on rat samples . Sci Adv (2021) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; human; 1:1000; fig ev5a
BD Biosciences Gga3 antibody (BD Transduction, 610385) was used in western blot on human samples at 1:1000 (fig ev5a). EMBO Rep (2020) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; mouse; 1:1000; loading ...; fig ev4g
BD Biosciences Gga3 antibody (BD Transduction, 610501) was used in western blot on mouse samples at 1:1000 (fig ev4g). EMBO Rep (2020) ncbi
mouse monoclonal (8/Adaptin)
  • immunocytochemistry; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 3e
BD Biosciences Gga3 antibody (BD Biosciences, 610502) was used in immunocytochemistry on human samples (fig 3d) and in western blot on human samples (fig 3e). Dev Cell (2019) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; mouse; 1:1000; loading ...; fig 4a
BD Biosciences Gga3 antibody (BD Biosciences, 610502) was used in western blot on mouse samples at 1:1000 (fig 4a). Cell Rep (2019) ncbi
mouse monoclonal (8/Adaptin)
BD Biosciences Gga3 antibody (BD Biosciences, 610502) was used . elife (2019) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; human; 1:200; loading ...; fig s2d
BD Biosciences Gga3 antibody (BD Bioscience, 610386) was used in immunocytochemistry on human samples at 1:200 (fig s2d). J Cell Sci (2019) ncbi
mouse monoclonal (8/Adaptin)
  • immunoprecipitation; mouse; 1:1000; loading ...; fig 2a
  • immunocytochemistry; mouse; 1:500; loading ...; fig 6c
  • western blot; mouse; 1:500; loading ...; fig 2a
  • western blot; human; 1:500; loading ...; fig s3c
BD Biosciences Gga3 antibody (BD Biosciences, 610502) was used in immunoprecipitation on mouse samples at 1:1000 (fig 2a), in immunocytochemistry on mouse samples at 1:500 (fig 6c), in western blot on mouse samples at 1:500 (fig 2a) and in western blot on human samples at 1:500 (fig s3c). Nat Commun (2017) ncbi
mouse monoclonal (88/Adaptin)
  • immunoprecipitation; mouse; 1:1000; loading ...; fig s3b
  • western blot; mouse; 1:1000; loading ...; fig s3b
BD Biosciences Gga3 antibody (BD Biosciences, 610386) was used in immunoprecipitation on mouse samples at 1:1000 (fig s3b) and in western blot on mouse samples at 1:1000 (fig s3b). Nat Commun (2017) ncbi
mouse monoclonal (74/Adaptin)
  • western blot; human; 1:1000; loading ...; fig s14b
In order to examine haploinsufficiency network analyses to identify which somatic copy-number alteration patterns are most disruptive in ovarian cancer, BD Biosciences Gga3 antibody (BD, 610382) was used in western blot on human samples at 1:1000 (fig s14b). Nat Commun (2017) ncbi
mouse monoclonal (88/Adaptin)
  • immunohistochemistry - frozen section; mouse; fig 7e
  • immunohistochemistry; mouse; fig s4d
BD Biosciences Gga3 antibody (BD Transduction Laboratories, 610386) was used in immunohistochemistry - frozen section on mouse samples (fig 7e) and in immunohistochemistry on mouse samples (fig s4d). Cell Death Dis (2017) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; mouse; fig 4
BD Biosciences Gga3 antibody (BD, 610386) was used in western blot on mouse samples (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4b
In order to propose that ikarugamycin is a useful reagent to study routes of endocytic trafficking, BD Biosciences Gga3 antibody (BD Pharmingen, 610385) was used in immunocytochemistry on human samples (fig 4a) and in western blot on human samples (fig 4b). Traffic (2016) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; human; fig s1
BD Biosciences Gga3 antibody (BD Bioscience, 610386) was used in western blot on human samples (fig s1). BMC Biol (2016) ncbi
mouse monoclonal (74/Adaptin)
  • immunocytochemistry; human; fig 3
  • western blot; human; 1:1000; fig 3
BD Biosciences Gga3 antibody (BD Biosciences, 610382) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples at 1:1000 (fig 3). Drug Des Devel Ther (2016) ncbi
mouse monoclonal (74/Adaptin)
  • immunocytochemistry; African green monkey; 1:1000; fig s1
In order to learn the requirement of palmitoylation at the Golgi by activation of STING, BD Biosciences Gga3 antibody (BD Biosciences, 610382) was used in immunocytochemistry on African green monkey samples at 1:1000 (fig s1). Nat Commun (2016) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human; 1:1000; fig 6
BD Biosciences Gga3 antibody (BD Biosciences, 610502) was used in western blot on human samples at 1:1000 (fig 6). PLoS ONE (2016) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human; 1:1000; fig 2
BD Biosciences Gga3 antibody (BD Transduction Laboratories, 610502) was used in western blot on human samples at 1:1000 (fig 2). elife (2016) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; mouse
BD Biosciences Gga3 antibody (BD-Bioscience, 610502) was used in western blot on mouse samples . J Lipid Res (2016) ncbi
mouse monoclonal (74/Adaptin)
  • immunocytochemistry; mouse; fig s4
  • western blot; mouse; fig s4
BD Biosciences Gga3 antibody (BD, 610381) was used in immunocytochemistry on mouse samples (fig s4) and in western blot on mouse samples (fig s4). Sci Rep (2016) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; mouse; 1:100; fig 5a
  • western blot; mouse; fig 1
In order to determine the affects of dendritic cell migration in vitro by loss of gadkin, BD Biosciences Gga3 antibody (BD Biosciences, 610386) was used in immunocytochemistry on mouse samples at 1:100 (fig 5a) and in western blot on mouse samples (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; rat; fig 1
In order to characterize inhibition of clathrin-mediated and bulk endocytosis by synaptotagmin-11, BD Biosciences Gga3 antibody (BD Transduction Laboratories, 610501) was used in western blot on rat samples (fig 1). EMBO Rep (2016) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; rat; 1:5000
In order to localize ADAM10 and BACE1 in synaptic vesicles, BD Biosciences Gga3 antibody (BD Biosciences, 610386) was used in western blot on rat samples at 1:5000. J Neurochem (2015) ncbi
mouse monoclonal (8/Adaptin)
  • immunohistochemistry - paraffin section; mouse; fig 4,5
In order to study the role of excitotoxicity in neuronal death, BD Biosciences Gga3 antibody (BD Biosciences, 610502) was used in immunohistochemistry - paraffin section on mouse samples (fig 4,5). J Neurosci (2015) ncbi
mouse monoclonal (8/Adaptin)
  • immunocytochemistry; mouse
BD Biosciences Gga3 antibody (BD Pharmingen, 610502) was used in immunocytochemistry on mouse samples . Med Microbiol Immunol (2015) ncbi
mouse monoclonal (8/Adaptin)
  • immunocytochemistry; African green monkey; fig s2d
  • western blot; human; fig s1f
In order to identify and characterize a new endocytic route that is called fast endophilin-mediated endocytosis, BD Biosciences Gga3 antibody (BD, 610501) was used in immunocytochemistry on African green monkey samples (fig s2d) and in western blot on human samples (fig s1f). Nature (2015) ncbi
mouse monoclonal (8/Adaptin)
  • immunohistochemistry - paraffin section; mouse; 1:800; fig 4
BD Biosciences Gga3 antibody (BD Transduction Lab, 610501) was used in immunohistochemistry - paraffin section on mouse samples at 1:800 (fig 4). PLoS ONE (2014) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human; 1:1000; loading ...; fig 5b
BD Biosciences Gga3 antibody (BD Transduction Laboratories, 610502) was used in western blot on human samples at 1:1000 (fig 5b). elife (2014) ncbi
mouse monoclonal (88/Adaptin)
  • immunocytochemistry; human
BD Biosciences Gga3 antibody (BD Bioscience, 610386) was used in immunocytochemistry on human samples . Mol Brain (2014) ncbi
mouse monoclonal (88/Adaptin)
  • western blot; human
BD Biosciences Gga3 antibody (BD Transduction, 610386) was used in western blot on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (8/Adaptin)
  • western blot; human
BD Biosciences Gga3 antibody (BD Biosciences, 610502) was used in western blot on human samples . Mol Biol Cell (2013) ncbi
mouse monoclonal (88/Adaptin)
  • flow cytometry; human
In order to show that BRAG2 acts at clathrin-coated pits to promote integrin internalization by activating Arf5, BD Biosciences Gga3 antibody (BD, 610385) was used in flow cytometry on human samples . J Biol Chem (2012) ncbi
mouse monoclonal (74/Adaptin)
  • flow cytometry; human
In order to show that BRAG2 acts at clathrin-coated pits to promote integrin internalization by activating Arf5, BD Biosciences Gga3 antibody (BD, 610381) was used in flow cytometry on human samples . J Biol Chem (2012) ncbi
mouse monoclonal (88/Adaptin)
  • other; human; loading ...; tbl 5.1
In order to describe organelle-co-localized cell arrays, BD Biosciences Gga3 antibody (BD Biosciences, 610385) was used in other on human samples (tbl 5.1). Methods Mol Biol (2011) ncbi
Articles Reviewed
  1. Hausrat T, Janiesch P, Breiden P, Lutz D, Hoffmeister Ullerich S, Hermans Borgmeyer I, et al. Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in mice. Nat Commun. 2022;13:4192 pubmed publisher
  2. Azarnia Tehran D, Kochlamazashvili G, Pampaloni N, Sposini S, Shergill J, Lehmann M, et al. Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity. Sci Adv. 2022;8:eabl5032 pubmed publisher
  3. López Gambero A, Rosell Valle C, Medina Vera D, Navarro J, Vargas A, Rivera P, et al. A Negative Energy Balance Is Associated with Metabolic Dysfunctions in the Hypothalamus of a Humanized Preclinical Model of Alzheimer's Disease, the 5XFAD Mouse. Int J Mol Sci. 2021;22: pubmed publisher
  4. Ivanova D, Dobson K, Gajbhiye A, Davenport E, Hacker D, Ultanir S, et al. Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes. Sci Adv. 2021;7: pubmed publisher
  5. Bera S, Camblor Perujo S, Calleja Barca E, Negrete Hurtado A, Racho J, de Bruyckere E, et al. AP-2 reduces amyloidogenesis by promoting BACE1 trafficking and degradation in neurons. EMBO Rep. 2020;21:e47954 pubmed publisher
  6. Gulbranson D, Crisman L, Lee M, Ouyang Y, Menasche B, Demmitt B, et al. AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated Endocytosis. Dev Cell. 2019;50:436-446.e5 pubmed publisher
  7. Wagner W, Lippmann K, Heisler F, Gromova K, Lombino F, Roesler M, et al. Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. Cell Rep. 2019;28:11-20.e9 pubmed publisher
  8. Zavodszky E, Hegde R. Misfolded GPI-anchored proteins are escorted through the secretory pathway by ER-derived factors. elife. 2019;8: pubmed publisher
  9. Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, et al. A SEPT1-based scaffold is required for Golgi integrity and function. J Cell Sci. 2019;132: pubmed publisher
  10. Bagh M, Peng S, Chandra G, Zhang Z, Singh S, Pattabiraman N, et al. Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model. Nat Commun. 2017;8:14612 pubmed publisher
  11. Delaney J, Patel C, Willis K, Haghighiabyaneh M, Axelrod J, Tancioni I, et al. Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. 2017;8:14423 pubmed publisher
  12. Han F, Liu C, Zhang L, Zhou Y, Qin Y, Wang Y, et al. Globozoospermia and lack of acrosome formation in GM130-deficient mice. Cell Death Dis. 2017;8:e2532 pubmed publisher
  13. Candiello E, Kratzke M, Wenzel D, Cassel D, Schu P. AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway. Sci Rep. 2016;6:29950 pubmed publisher
  14. Elkin S, Oswald N, Reed D, Mettlen M, Macmillan J, Schmid S. Ikarugamycin: A Natural Product Inhibitor of Clathrin-Mediated Endocytosis. Traffic. 2016;17:1139-49 pubmed publisher
  15. Nkwe D, Pelchen Matthews A, Burden J, Collinson L, Marsh M. The intracellular plasma membrane-connected compartment in the assembly of HIV-1 in human macrophages. BMC Biol. 2016;14:50 pubmed publisher
  16. Davis M, Delaney J, Patel C, Storgard R, Stupack D. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016;10:1837-46 pubmed publisher
  17. Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
  18. O Santos A, Parrini M, Camonis J. RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases. PLoS ONE. 2016;11:e0154840 pubmed publisher
  19. Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel Studer I, Meyer Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed publisher
  20. Tao W, Moore R, Meng Y, Smith E, Xu X. Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol. J Lipid Res. 2016;57:809-17 pubmed publisher
  21. Bhattacharyya S, Rainey M, Arya P, Mohapatra B, Mushtaq I, Dutta S, et al. Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016;6:20727 pubmed publisher
  22. Schachtner H, Weimershaus M, Stache V, Plewa N, Legler D, Höpken U, et al. Loss of Gadkin Affects Dendritic Cell Migration In Vitro. PLoS ONE. 2015;10:e0143883 pubmed publisher
  23. Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, et al. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep. 2016;17:47-63 pubmed publisher
  24. Lundgren J, Ahmed S, Schedin Weiss S, Gouras G, Winblad B, Tjernberg L, et al. ADAM10 and BACE1 are localized to synaptic vesicles. J Neurochem. 2015;135:606-15 pubmed publisher
  25. Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed publisher
  26. Fink A, Blaum F, Babic Cac M, Ebert S, Lemmermann N, Reddehase M. An endocytic YXXΦ (YRRF) cargo sorting motif in the cytoplasmic tail of murine cytomegalovirus AP2 'adapter adapter' protein m04/gp34 antagonizes virus evasion of natural killer cells. Med Microbiol Immunol. 2015;204:383-94 pubmed publisher
  27. Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed publisher
  28. Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed publisher
  29. Tao W, Moore R, Smith E, Xu X. Hormonal induction and roles of Disabled-2 in lactation and involution. PLoS ONE. 2014;9:e110737 pubmed publisher
  30. Umasankar P, Ma L, Thieman J, Jha A, Doray B, Watkins S, et al. A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing. elife. 2014;3: pubmed publisher
  31. Tam J, Seah C, Pasternak S. The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid. Mol Brain. 2014;7:54 pubmed publisher
  32. Stahlschmidt W, Robertson M, Robinson P, McCluskey A, Haucke V. Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors. J Biol Chem. 2014;289:4906-18 pubmed publisher
  33. Hirst J, Borner G, Edgar J, Hein M, Mann M, Buchholz F, et al. Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15. Mol Biol Cell. 2013;24:2558-69 pubmed publisher
  34. Moravec R, Conger K, D Souza R, Allison A, Casanova J. BRAG2/GEP100/IQSec1 interacts with clathrin and regulates ?5?1 integrin endocytosis through activation of ADP ribosylation factor 5 (Arf5). J Biol Chem. 2012;287:31138-47 pubmed publisher
  35. Hu Y, Janitz M. High-throughput subcellular protein localization using transfected-cell arrays. Subcellular protein localization using cell arrays. Methods Mol Biol. 2011;706:53-72 pubmed publisher