This is a Validated Antibody Database (VAD) review about rat Gabra5, based on 6 published articles (read how Labome selects the articles), using Gabra5 antibody in all methods. It is aimed to help Labome visitors find the most suited Gabra5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Gabra5 synonym: gamma-aminobutyric acid receptor subunit alpha-5; GABA(A) receptor subunit alpha-5; GABA-A receptor alpha-5 subunit; gamma-aminobutyric acid A receptor, alpha 5; gamma-aminobutyric acid (GABA) A receptor, alpha 5; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5

Knockout validation
Synaptic Systems
rabbit polyclonal (/)
  • immunohistochemistry knockout validation; mouse; 1:500; loading ...; fig 1b
In order to ask if alpha-5GABA receptors create tonic conductance in the spinal cord dorsal horn to constrain nociception, Synaptic Systems Gabra5 antibody (Synaptic Systems, 224 503) was used in immunohistochemistry knockout validation on mouse samples at 1:500 (fig 1b). J Neurosci Res (2017) ncbi
Abcam
rabbit monoclonal (EPR12262)
  • western blot; mouse; fig 2h
Abcam Gabra5 antibody (Abcam, ab175195) was used in western blot on mouse samples (fig 2h). elife (2017) ncbi
rabbit polyclonal
  • western blot; rat; 1:3000; fig 4a
In order to investigate the mechanism by which oxytocin attenuates oxygen-glucose deprivation-reperfusion injury, Abcam Gabra5 antibody (Abcam, ab10098) was used in western blot on rat samples at 1:3000 (fig 4a). Sci Rep (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; fig 6
In order to investigate the contribution of GABA inhibition in the dentate gyrus in Alzheimer's disease, Abcam Gabra5 antibody (Abcam, ab10098) was used in immunocytochemistry on mouse samples at 1:200 (fig 6). Nat Commun (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:500
Abcam Gabra5 antibody (Abcam, AB10098) was used in western blot on human samples at 1:500. Transl Psychiatry (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (E-8)
  • western blot; rat; 1:500; loading ...; fig 8a
In order to study the impact of diet and stress on adult rat behavior and hippocampal plasticity, Santa Cruz Biotechnology Gabra5 antibody (Santa Cruz Biotechnology, sc-376282) was used in western blot on rat samples at 1:500 (fig 8a). Mol Neurobiol (2018) ncbi
Synaptic Systems
rabbit polyclonal (/)
  • immunohistochemistry knockout validation; mouse; 1:500; loading ...; fig 1b
In order to ask if alpha-5GABA receptors create tonic conductance in the spinal cord dorsal horn to constrain nociception, Synaptic Systems Gabra5 antibody (Synaptic Systems, 224 503) was used in immunohistochemistry knockout validation on mouse samples at 1:500 (fig 1b). J Neurosci Res (2017) ncbi
Articles Reviewed
  1. Arcego D, Toniazzo A, Krolow R, Lampert C, Berlitz C, Dos Santos Garcia E, et al. Impact of High-Fat Diet and Early Stress on Depressive-Like Behavior and Hippocampal Plasticity in Adult Male Rats. Mol Neurobiol. 2018;55:2740-2753 pubmed publisher
  2. Chen M, Wang J, Jiang J, Zheng X, Justice N, Wang K, et al. APP modulates KCC2 expression and function in hippocampal GABAergic inhibition. elife. 2017;6: pubmed publisher
  3. Perez Sanchez J, Lorenzo L, Lecker I, Zurek A, Labrakakis C, Bridgwater E, et al. ?5GABAA Receptors Mediate Tonic Inhibition in the Spinal Cord Dorsal Horn and Contribute to the Resolution Of Hyperalgesia. J Neurosci Res. 2017;95:1307-1318 pubmed publisher
  4. Kaneko Y, Pappas C, Tajiri N, Borlongan C. Oxytocin modulates GABAAR subunits to confer neuroprotection in stroke in vitro. Sci Rep. 2016;6:35659 pubmed publisher
  5. Wu Z, Guo Z, Gearing M, Chen G. Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer's [corrected] disease model. Nat Commun. 2014;5:4159 pubmed publisher
  6. Fatemi S, Folsom T, Rooney R, Thuras P. Expression of GABAA ?2-, ?1- and ?-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder. Transl Psychiatry. 2013;3:e303 pubmed publisher