This is a Validated Antibody Database (VAD) review about rat Ftl1, based on 14 published articles (read how Labome selects the articles), using Ftl1 antibody in all methods. It is aimed to help Labome visitors find the most suited Ftl1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ftl1 synonym: Ftl

Knockout validation
Abcam
domestic rabbit monoclonal (EPR5260)
  • immunohistochemistry knockout validation; mouse; fig 3
  • western blot knockout validation; mouse; fig 4
  • immunohistochemistry - paraffin section; mouse; fig 3
In order to use Fth and Ftl knock out mice to study iron metabolism in the brain, Abcam Ftl1 antibody (Abcam, ab109373) was used in immunohistochemistry knockout validation on mouse samples (fig 3), in western blot knockout validation on mouse samples (fig 4) and in immunohistochemistry - paraffin section on mouse samples (fig 3). PLoS ONE (2015) ncbi
Abcam
domestic rabbit monoclonal (EPR5260)
  • western blot; human; 1:10,000; loading ...; fig 3a
Abcam Ftl1 antibody (Abcam, ab109373) was used in western blot on human samples at 1:10,000 (fig 3a). Oxid Med Cell Longev (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...
Abcam Ftl1 antibody (Abcam, ab69090) was used in western blot on human samples . Theranostics (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig s7
  • western blot; human; 1:1000; fig s5c
Abcam Ftl1 antibody (Abcam, ab69090) was used in immunocytochemistry on human samples (fig s7) and in western blot on human samples at 1:1000 (fig s5c). Nat Commun (2021) ncbi
domestic rabbit monoclonal (EPR5260)
  • western blot; mouse; loading ...; fig 4c, 4d
Abcam Ftl1 antibody (Abcam, ab109373) was used in western blot on mouse samples (fig 4c, 4d). Cell Death Discov (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1e
Abcam Ftl1 antibody (Abcam, ab69090) was used in immunohistochemistry on mouse samples at 1:500 (fig 1e). Front Cell Neurosci (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:800; loading ...; fig 3a, 3s5a
Abcam Ftl1 antibody (Abcam, ab69090) was used in western blot on human samples at 1:800 (fig 3a, 3s5a). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2e
  • western blot; rat; loading ...; fig 2e
Abcam Ftl1 antibody (Abcam, ab69090) was used in western blot on human samples (fig 2e) and in western blot on rat samples (fig 2e). Cancer Lett (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:5000; loading ...; fig 5
In order to report polyphenols with iron-chelating potential, Abcam Ftl1 antibody (Abcam, AB69090) was used in western blot on human samples at 1:5000 (fig 5). Mol Nutr Food Res (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; fig 2D
In order to report the transcriptomes of thousands of single pancreatic cells, Abcam Ftl1 antibody (Abcam, ab69090) was used in immunohistochemistry on human samples (fig 2D). Cell Syst (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 7a
In order to develop StemID, an algorithm for identifying stem cells among all detectable cell types within a population, Abcam Ftl1 antibody (Abcam, ab69090) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 7a). Cell Stem Cell (2016) ncbi
domestic rabbit monoclonal (EPR5260)
  • immunohistochemistry knockout validation; mouse; fig 3
  • western blot knockout validation; mouse; fig 4
  • immunohistochemistry - paraffin section; mouse; fig 3
In order to use Fth and Ftl knock out mice to study iron metabolism in the brain, Abcam Ftl1 antibody (Abcam, ab109373) was used in immunohistochemistry knockout validation on mouse samples (fig 3), in western blot knockout validation on mouse samples (fig 4) and in immunohistochemistry - paraffin section on mouse samples (fig 3). PLoS ONE (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-1)
  • western blot; mouse; loading ...; fig 1d
Santa Cruz Biotechnology Ftl1 antibody (Santa Cruz, sc-390558) was used in western blot on mouse samples (fig 1d). Cell Death Dis (2020) ncbi
mouse monoclonal (D-1)
  • western blot; human; 1:1000; loading ...; fig 4b
In order to study the role of mitochondrial ferritin protein in iron-dependent cell death (ferroptosis)., Santa Cruz Biotechnology Ftl1 antibody (Santa Cruz, sc-390558) was used in western blot on human samples at 1:1000 (fig 4b). Front Aging Neurosci (2016) ncbi
mouse monoclonal (D-1)
  • western blot; human; 1:1000; fig 4
In order to characterize inhibition of neuronal tumor cell proliferation by mitochondrial ferritin, Santa Cruz Biotechnology Ftl1 antibody (Santa Cruz Biotechnology, sc-390558) was used in western blot on human samples at 1:1000 (fig 4). Cell Mol Life Sci (2015) ncbi
Articles Reviewed
  1. Zuo Y, Xie J, Li X, Li Y, Thirupathi A, Zhang J, et al. Ferritinophagy-Mediated Ferroptosis Involved in Paraquat-Induced Neurotoxicity of Dopaminergic Neurons: Implication for Neurotoxicity in PD. Oxid Med Cell Longev. 2021;2021:9961628 pubmed publisher
  2. Zhang X, Yu K, Ma L, Qian Z, Tian X, Miao Y, et al. Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma. Theranostics. 2021;11:5650-5674 pubmed publisher
  3. Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed publisher
  4. Zhang X, Gou Y, Zhang Y, Li J, Han K, Xu Y, et al. Hepcidin overexpression in astrocytes alters brain iron metabolism and protects against amyloid-β induced brain damage in mice. Cell Death Discov. 2020;6:113 pubmed publisher
  5. Lee D, Kam M, Lee S, Lee H, Lee D. Peroxiredoxin 5 deficiency exacerbates iron overload-induced neuronal death via ER-mediated mitochondrial fission in mouse hippocampus. Cell Death Dis. 2020;11:204 pubmed publisher
  6. Kjell J, Gotz M. Filling the Gaps - A Call for Comprehensive Analysis of Extracellular Matrix of the Glial Scar in Region- and Injury-Specific Contexts. Front Cell Neurosci. 2020;14:32 pubmed publisher
  7. Pulos Holmes M, Srole D, Juarez M, Lee A, McSwiggen D, Ingolia N, et al. Repression of ferritin light chain translation by human eIF3. elife. 2019;8: pubmed publisher
  8. Wang Z, Ding Y, Wang X, Lu S, Wang C, He C, et al. Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT. Cancer Lett. 2018;428:21-33 pubmed publisher
  9. Wang Y, Chang S, Wu Q, Gou Y, Jia L, Cui Y, et al. The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis. Front Aging Neurosci. 2016;8:308 pubmed publisher
  10. Horniblow R, Henesy D, Iqbal T, Tselepis C. Modulation of iron transport, metabolism and reactive oxygen status by quercetin-iron complexes in vitro. Mol Nutr Food Res. 2017;61: pubmed publisher
  11. Muraro M, Dharmadhikari G, Grün D, Groen N, Dielen T, Jansen E, et al. A Single-Cell Transcriptome Atlas of the Human Pancreas. Cell Syst. 2016;3:385-394.e3 pubmed publisher
  12. Grün D, Muraro M, Boisset J, Wiebrands K, Lyubimova A, Dharmadhikari G, et al. De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data. Cell Stem Cell. 2016;19:266-277 pubmed publisher
  13. Li W, Garringer H, GOODWIN C, Richine B, Acton A, Vanduyn N, et al. Systemic and cerebral iron homeostasis in ferritin knock-out mice. PLoS ONE. 2015;10:e0117435 pubmed publisher
  14. Shi Z, Shi F, Wang Y, Sheftel A, Nie G, Zhao Y, et al. Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation. Cell Mol Life Sci. 2015;72:983-97 pubmed publisher