This is a Validated Antibody Database (VAD) review about rat Fhit, based on 2 published articles (read how Labome selects the articles), using Fhit antibody in all methods. It is aimed to help Labome visitors find the most suited Fhit antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Fhit synonym: bis(5'-adenosyl)-triphosphatase; AP3A hydrolase; AP3Aase; diadenosine 5',5'''-P1,P3-triphosphate hydrolase; dinucleosidetriphosphatase; fragile histidine triad protein

Invitrogen
rabbit polyclonal
  • western blot; human; 1:250
In order to investigate the mechanism of fragile histidine triad-mediated regulation of epithelial-mesenchymal transition, Invitrogen Fhit antibody (Zymed, ZR44) was used in western blot on human samples at 1:250. Mol Cancer Res (2014) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:500; fig 2
In order to study the fragile histidine triad gene in microsatellite instable, microsatellite stable, and CpG island methylator phenotypes of colorectal cancer subtypes, Invitrogen Fhit antibody (Invitrogen, 71-9000) was used in immunohistochemistry on human samples at 1:500 (fig 2). J Histochem Cytochem (2013) ncbi
Articles Reviewed
  1. Joannes A, Grelet S, Duca L, Gilles C, Kileztky C, Dalstein V, et al. Fhit regulates EMT targets through an EGFR/Src/ERK/Slug signaling axis in human bronchial cells. Mol Cancer Res. 2014;12:775-83 pubmed publisher
  2. Al Temaimi R, Jacob S, Al Ali W, Thomas D, Al Mulla F. Reduced FHIT expression is associated with mismatch repair deficient and high CpG island methylator phenotype colorectal cancer. J Histochem Cytochem. 2013;61:627-38 pubmed publisher