This is a Validated Antibody Database (VAD) review about rat Erbb2, based on 97 published articles (read how Labome selects the articles), using Erbb2 antibody in all methods. It is aimed to help Labome visitors find the most suited Erbb2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (29D8)
  • western blot knockout validation; human; 1:200; fig 1a
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2165) was used in western blot knockout validation on human samples at 1:200 (fig 1a). Cancers (Basel) (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (3B5)
  • immunohistochemistry; mouse; 1:50; loading ...; fig 4b
Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, 3B5) was used in immunohistochemistry on mouse samples at 1:50 (fig 4b). BMC Dev Biol (2021) ncbi
mouse monoclonal
  • immunohistochemistry; mouse; 1:50; loading ...; fig 4b
Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, 3B5) was used in immunohistochemistry on mouse samples at 1:50 (fig 4b). BMC Dev Biol (2021) ncbi
mouse monoclonal (3B5)
  • western blot; human; loading ...; fig 4g
Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, sc-33684) was used in western blot on human samples (fig 4g). Theranostics (2021) ncbi
mouse monoclonal (3B5)
  • flow cytometry; human; loading ...; fig s4b
Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, sc-33684) was used in flow cytometry on human samples (fig s4b). MBio (2017) ncbi
mouse monoclonal
  • ChIP-Seq; mouse; fig s3a
  • chromatin immunoprecipitation; mouse; fig s3b
  • ChIP-Seq; human; loading ...; fig s3c
  • chromatin immunoprecipitation; human; fig s3e
Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz Biotechnology, 3B5) was used in ChIP-Seq on mouse samples (fig s3a), in chromatin immunoprecipitation on mouse samples (fig s3b), in ChIP-Seq on human samples (fig s3c) and in chromatin immunoprecipitation on human samples (fig s3e). PLoS Genet (2017) ncbi
mouse monoclonal (3B5)
  • ChIP-Seq; human; loading ...; fig s3c
  • chromatin immunoprecipitation; human; fig s3e
  • ChIP-Seq; mouse; fig s3a
  • chromatin immunoprecipitation; mouse; fig s3b
Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz Biotechnology, 3B5) was used in ChIP-Seq on human samples (fig s3c), in chromatin immunoprecipitation on human samples (fig s3e), in ChIP-Seq on mouse samples (fig s3a) and in chromatin immunoprecipitation on mouse samples (fig s3b). PLoS Genet (2017) ncbi
mouse monoclonal (3B5)
  • western blot; human; 1:1000; fig 2
In order to assess the role of Nrg1 signaling to Alzheimer's disease pathogenesis, Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, sc-33684) was used in western blot on human samples at 1:1000 (fig 2). Mol Med Rep (2016) ncbi
mouse monoclonal (19G5)
  • western blot; human; loading ...; fig 5c
In order to determine the effect of a mixture of two monoclonal antibodies against non-overlapping epitopes of HER2 on HER2 stability and localization, Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, 19G5) was used in western blot on human samples (fig 5c). J Cell Mol Med (2016) ncbi
mouse monoclonal (3B5)
  • western blot; mouse; 1:500; fig 2
In order to study the alterations of brain Neuregulin-1 signaling during neuroinflammation, Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, sc-33684) was used in western blot on mouse samples at 1:500 (fig 2). Mol Med Rep (2016) ncbi
mouse monoclonal (F-11)
  • immunoprecipitation; human; fig 1
Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, sc-7301) was used in immunoprecipitation on human samples (fig 1). Oncogenesis (2016) ncbi
mouse monoclonal (3B5)
  • immunohistochemistry - paraffin section; human; tbl 3
Santa Cruz Biotechnology Erbb2 antibody (SantaCruz, sc-33684) was used in immunohistochemistry - paraffin section on human samples (tbl 3). Genes Cancer (2015) ncbi
mouse monoclonal (F-11)
  • western blot; human; fig 3A
In order to elucidate the dimerization of ErbB2, Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz, sc-7301) was used in western blot on human samples (fig 3A). Oncotarget (2015) ncbi
mouse monoclonal (3B5)
  • western blot; human
Santa Cruz Biotechnology Erbb2 antibody (Santa Cruz Biotechnology, sc-33684) was used in western blot on human samples . Int J Oncol (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR19547-12)
  • immunohistochemistry - paraffin section; human; 1:200; fig s1c
Abcam Erbb2 antibody (Abcam, ab214275) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s1c). Sci Adv (2022) ncbi
domestic rabbit monoclonal (EPR19547-12)
  • immunohistochemistry; human; 1:1000; loading ...; fig s4
Abcam Erbb2 antibody (Abcam, ab214275) was used in immunohistochemistry on human samples at 1:1000 (fig s4). NPJ Breast Cancer (2021) ncbi
mouse monoclonal (3B5)
  • immunohistochemistry; mouse; loading ...; fig 2g
Abcam Erbb2 antibody (Abcam, AB16901) was used in immunohistochemistry on mouse samples (fig 2g). Nature (2017) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 3d
In order to develop a microfluidic immunostaining system for the standardization of immunohistochemical assays, Invitrogen Erbb2 antibody (Thermo Fisher, PA5-16305) was used in immunohistochemistry - paraffin section on human samples (fig 3d). Sci Rep (2017) ncbi
mouse monoclonal (PN2A)
  • western blot; human; 1:500; loading ...; fig 2d
In order to identify a role for S100P in the development of trastuzumab-resistance, Invitrogen Erbb2 antibody (Fisher, MS-1072-P0) was used in western blot on human samples at 1:500 (fig 2d). Oncotarget (2016) ncbi
mouse monoclonal (PN2A)
  • western blot; human; 1:200; fig 1
In order to study anti-tumor activity of breast cancer models resistant to anti-HER2 drugs due to a dual fatty acid synthase and HER2 signaling blockade, Invitrogen Erbb2 antibody (Thermo Scientific, MS-1072-P1) was used in western blot on human samples at 1:200 (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (PN2A)
  • immunohistochemistry - paraffin section; human
In order to establish a tissue quality index as an intrinsic control for measurement of different effects of preanalytical variables on FFPE tissue, Invitrogen Erbb2 antibody (Thermo, PN2A) was used in immunohistochemistry - paraffin section on human samples . Lab Invest (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D8F12)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s5a
  • western blot; human; 1:1000; fig 1f
Cell Signaling Technology Erbb2 antibody (CST, 8609) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig s5a) and in western blot on human samples at 1:1000 (fig 1f). Allergy Asthma Immunol Res (2022) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; 1:1000; fig 4a
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290S) was used in western blot on human samples at 1:1000 (fig 4a). Nature (2022) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; loading ...; fig 6a, 6b, 6c, 6d
Cell Signaling Technology Erbb2 antibody (CST, 4290) was used in western blot on human samples (fig 6a, 6b, 6c, 6d). Cell Oncol (Dordr) (2022) ncbi
domestic rabbit monoclonal (D8F12)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in immunohistochemistry - paraffin section on mouse samples (fig 2a). Cancers (Basel) (2022) ncbi
domestic rabbit monoclonal (29D8)
  • immunohistochemistry; mouse; 1:500
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in immunohistochemistry on mouse samples at 1:500. Nat Commun (2022) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290S) was used in western blot on human samples (fig 3a). Thorac Cancer (2022) ncbi
domestic rabbit monoclonal (29D8)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 4b
Cell Signaling Technology Erbb2 antibody (CST, 2165) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 4b). Nat Cancer (2022) ncbi
domestic rabbit monoclonal (29D8)
  • immunoprecipitation; mouse; 1:100; loading ...; fig 11
  • western blot; mouse; 1:1000; loading ...; fig 9e
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in immunoprecipitation on mouse samples at 1:100 (fig 11) and in western blot on mouse samples at 1:1000 (fig 9e). J Clin Invest (2022) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; mouse; 1:1000; loading ...; fig 3a
  • western blot; human; 1:1000; loading ...; fig 3b, s4c
Cell Signaling Technology Erbb2 antibody (Cell signaling, 29D8) was used in western blot on mouse samples at 1:1000 (fig 3a) and in western blot on human samples at 1:1000 (fig 3b, s4c). Proc Natl Acad Sci U S A (2021) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; 1:1000; loading ...; fig s1a
Cell Signaling Technology Erbb2 antibody (CST, 4290) was used in western blot on human samples at 1:1000 (fig s1a). NPJ Breast Cancer (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology Erbb2 antibody (CST, 3250s) was used in western blot on mouse samples (fig 4b). J Cell Mol Med (2021) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig 6a). J Exp Clin Cancer Res (2021) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; fig 1c
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig 1c). Am J Cancer Res (2021) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; mouse; 1:1000; fig 3c, 3e, 3f
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 4290) was used in western blot on mouse samples at 1:1000 (fig 3c, 3e, 3f). Arterioscler Thromb Vasc Biol (2021) ncbi
domestic rabbit monoclonal (29D8)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1g
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in immunohistochemistry on mouse samples at 1:500 (fig 1g). Oncogene (2021) ncbi
domestic rabbit monoclonal (29D8)
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2165) was used in immunocytochemistry on human samples (fig 2b) and in western blot on human samples (fig 2c). Theranostics (2021) ncbi
domestic rabbit monoclonal (29D8)
  • western blot knockout validation; human; 1:200; fig 1a
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2165) was used in western blot knockout validation on human samples at 1:200 (fig 1a). Cancers (Basel) (2021) ncbi
domestic rabbit monoclonal (29D8)
  • immunohistochemistry; mouse; loading ...; fig s2a
  • western blot; mouse; loading ...; fig s2b
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in immunohistochemistry on mouse samples (fig s2a) and in western blot on mouse samples (fig s2b). Cell Rep (2021) ncbi
domestic rabbit monoclonal (29D8)
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 1c
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 1c). Nat Commun (2021) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig s2f
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig s2f). Mol Oncol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2241) was used in western blot on mouse samples at 1:1000 (fig 4a). Cancer Sci (2021) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on mouse samples at 1:1000 (fig 4a). Cancer Sci (2021) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; mouse; 1:1000; loading ...; fig 8b
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 29D8) was used in western blot on mouse samples at 1:1000 (fig 8b). J Clin Invest (2021) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 3a). Cancer Res (2021) ncbi
domestic rabbit monoclonal (D8F12)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2). BMC Cancer (2020) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig 1b, 2b
Cell Signaling Technology Erbb2 antibody (CST, 29D8) was used in western blot on human samples (fig 1b, 2b). EBioMedicine (2020) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology Erbb2 antibody (CST, 2165) was used in western blot on human samples (fig 1a). Cell Commun Signal (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3d
Cell Signaling Technology Erbb2 antibody (Cell Signalling Technology, 2241) was used in western blot on mouse samples at 1:1000 (fig 3d). Breast Cancer Res (2019) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; mouse; loading ...; fig 4c
Cell Signaling Technology Erbb2 antibody (Cell Signalling, D8F12) was used in western blot on mouse samples (fig 4c). Nutrients (2019) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; loading ...; fig s2
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig s2). Breast Cancer Res (2019) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig s3b
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig s3b). Oncogene (2019) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; loading ...; fig 5e
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig 5e). Cell Res (2018) ncbi
domestic rabbit monoclonal (D8F12)
  • immunohistochemistry - paraffin section; human; 1:100; fig 6c
Cell Signaling Technology Erbb2 antibody (CST, 4290) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 6c). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in western blot on human samples at 1:1000 (fig 1e). Science (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2247) was used in western blot on human samples (fig 2b). Oncotarget (2017) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; mouse; 1:1000; loading ...; fig 1g
In order to observe a novel role for ErbB4 in macrophage apoptosis, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on mouse samples at 1:1000 (fig 1g). Cell Death Dis (2017) ncbi
domestic rabbit monoclonal (D8F12)
  • immunohistochemistry; human; 1:500; fig 7b
  • western blot; human; loading ...; fig 3c
In order to report that lactate dehydrogenase A phosphorylation results in pro-invasive, anti-anoikis, and pro-metastatic advantages to cancer cells, Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 4290) was used in immunohistochemistry on human samples at 1:500 (fig 7b) and in western blot on human samples (fig 3c). Oncogene (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3c
In order to report that lactate dehydrogenase A phosphorylation results in pro-invasive, anti-anoikis, and pro-metastatic advantages to cancer cells, Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2247) was used in western blot on human samples (fig 3c). Oncogene (2017) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; loading ...; fig 5a
In order to discover regions of rare genetic variation that contribute to emphysema with severe airflow obstruction, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in western blot on human samples (fig 5a). Am J Respir Crit Care Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s6
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2241) was used in western blot on human samples (fig s6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D8F12)
  • immunocytochemistry; human; 1:100; loading ...; fig 2b
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in immunocytochemistry on human samples at 1:100 (fig 2b) and in western blot on human samples (fig 2a). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3
In order to assess the contribution of amphiregulin, epidermal growth factor, heparin-binding epidermal growth factor, and transforming growth factor alpha in the responsiveness of gastric cancer cell lines to cetuximab and trastuzumab, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2247) was used in western blot on human samples at 1:1000 (fig 3). J Cancer Res Clin Oncol (2017) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; 1:1000; loading ...; fig 3
In order to assess the contribution of amphiregulin, epidermal growth factor, heparin-binding epidermal growth factor, and transforming growth factor alpha in the responsiveness of gastric cancer cell lines to cetuximab and trastuzumab, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples at 1:1000 (fig 3). J Cancer Res Clin Oncol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3a
In order to show that 2-hydroxyoleic acid treatment alters cell signaling and intracellular transport, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2241) was used in western blot on human samples (fig 3a). Oncotarget (2016) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; 1:1000; loading ...; fig 4g
In order to demonstrate the bipartite role of Hsp90 in chaperoning CRAF kinase, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165S) was used in western blot on human samples at 1:1000 (fig 4g). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:200; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2241) was used in western blot on human samples at 1:200 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (29D8)
  • flow cytometry; human; loading ...; fig 1a
  • immunocytochemistry; human
  • immunohistochemistry; human
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 29D8) was used in flow cytometry on human samples (fig 1a), in immunocytochemistry on human samples and in immunohistochemistry on human samples . Nature (2016) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig 2a
In order to study how CUB domain-containing protein1 contributes to metastasis and drug resistance, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 2a). Breast Cancer Res (2016) ncbi
domestic rabbit monoclonal (D8F12)
  • immunohistochemistry - paraffin section; human; loading ...; tbl 1
Cell Signaling Technology Erbb2 antibody (Cell signaling, D8F12) was used in immunohistochemistry - paraffin section on human samples (tbl 1). Oncotarget (2016) ncbi
domestic rabbit monoclonal (29D8)
  • immunoprecipitation; human; loading ...; fig s8
In order to determine the effect of a mixture of two monoclonal antibodies against non-overlapping epitopes of HER2 on HER2 stability and localization, Cell Signaling Technology Erbb2 antibody (Cell signaling, 29D8) was used in immunoprecipitation on human samples (fig s8). J Cell Mol Med (2016) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig 1a
In order to assess the importance of the IGF1R tyrosine kinase in triple-negative gastric cancer with and without oncogenic KRAS, BRAF or PI3K3CA mutations, Cell Signaling Technology Erbb2 antibody (Cell signaling, 2165) was used in western blot on human samples (fig 1a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3a
In order to investigate the interaction between MUC13 and HER2, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2247) was used in western blot on human samples (fig 3a). Oncogene (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5f
In order to identify genetic features regulating cell survival after exposure to radiation., Cell Signaling Technology Erbb2 antibody (Cell Signalling, 2247) was used in western blot on human samples at 1:1000 (fig 5f). Nat Commun (2016) ncbi
domestic rabbit monoclonal (29D8)
Cell Signaling Technology Erbb2 antibody (CST, 2165S) was used . Oncogenesis (2016) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; 1:500; fig 2
Cell Signaling Technology Erbb2 antibody (Cell signaling, 2165) was used in western blot on human samples at 1:500 (fig 2). elife (2016) ncbi
domestic rabbit monoclonal (D8F12)
  • immunohistochemistry - paraffin section; mouse; fig 6
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290) was used in immunohistochemistry - paraffin section on mouse samples (fig 6). Oncotarget (2016) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; fig 1b
In order to determine how hepatitis C virus activates a neuregulin-driven circuit to modify surface expression of growth factor receptors of the ErbB family, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 1b). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; fig 1
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2165) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
domestic rabbit monoclonal (29D8)
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 2
Cell Signaling Technology Erbb2 antibody (Cell Signalling, 2165S) was used in immunocytochemistry on human samples (fig 2) and in western blot on human samples (fig 2). Oxid Med Cell Longev (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse
  • western blot; human; fig 4
Cell Signaling Technology Erbb2 antibody (Cell Signalling, 2241S) was used in immunocytochemistry on mouse samples and in western blot on human samples (fig 4). Oxid Med Cell Longev (2016) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; 1:200; loading ...; fig 2b
In order to demonstrate that receptor tyrosine kinase-like orphan receptor 1 is a scaffold for cavin-1 and caveolin-1, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples at 1:200 (fig 2b). Nat Commun (2016) ncbi
mouse monoclonal (44E7)
  • western blot; human; 1:1000
In order to determine the mechanisms of resistance to the pan-HER family inhibitor AZD8931, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2248) was used in western blot on human samples at 1:1000. Dis Model Mech (2016) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; dogs; 1:1000; fig 5
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 4290S) was used in western blot on dogs samples at 1:1000 (fig 5). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; 1:1000; fig 7e
In order to test if ado-trastuzumab emtansine overcomes trastuzumab resistance in murine models of brain metastases, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples at 1:1000 (fig 7e). J Natl Cancer Inst (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5C; S6B
Cell Signaling Technology Erbb2 antibody (Cell Sgnaling, 2247) was used in western blot on human samples at 1:1000 (fig 5C; S6B). Mol Oncol (2016) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; 1:1000; loading ...; fig 5C; S6B
Cell Signaling Technology Erbb2 antibody (Cell Sgnaling, 29D8) was used in western blot on human samples at 1:1000 (fig 5C; S6B). Mol Oncol (2016) ncbi
domestic rabbit monoclonal (29D8)
  • immunocytochemistry; human; fig 4
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in immunocytochemistry on human samples (fig 4). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology Erbb2 antibody (Cell signaling, 4290) was used in western blot on human samples (fig 4a). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (29D8)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1f
In order to develop a non-cross-reactive multiplex to measure 8 common breast cancer biomarkers, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 29D8) was used in immunohistochemistry - paraffin section on human samples (fig 1f). Appl Immunohistochem Mol Morphol (2016) ncbi
mouse monoclonal (44E7)
  • western blot; human; fig 5b
  • western blot; mouse; fig 5b
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2248) was used in western blot on human samples (fig 5b) and in western blot on mouse samples (fig 5b). Mol Ther (2015) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; fig 4
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 4). EBioMedicine (2015) ncbi
domestic rabbit monoclonal (29D8)
  • immunohistochemistry - paraffin section; human; 1:25
In order to develop and characterize patient-derived primary xenografts to a model of muscle invasive bladder cancer, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in immunohistochemistry - paraffin section on human samples at 1:25. Oncotarget (2015) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; 1:100
In order to study the role of Tn expression and post-translationally modifications in pancreatic ductal adenocarcinoma, Cell Signaling Technology Erbb2 antibody (Cell Signaling, #2165) was used in western blot on human samples at 1:100. Mol Cancer (2015) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; mouse; 1:1000; loading ...; fig 5b
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on mouse samples at 1:1000 (fig 5b). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig 4f, 4g, 4h
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2165) was used in western blot on human samples (fig 4f, 4g, 4h). Oncotarget (2015) ncbi
domestic rabbit monoclonal (29D8)
In order to characterize capabilities and potentials of extracellular vesicle (EV) array, Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2165) was used . J Extracell Vesicles (2015) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2165) was used in western blot on human samples . J Diabetes (2016) ncbi
domestic rabbit monoclonal (29D8)
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 1
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 1). Breast Cancer Res (2015) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; fig s1
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig s1). Oncogene (2015) ncbi
mouse monoclonal (44E7)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 2248) was used in western blot on human samples at 1:1000 (fig 2). elife (2014) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human
In order to identify mechanisms by which metastatic gastroesophageal adenocarcinomas develop resistance to ERBB2 inhibition, Cell Signaling Technology Erbb2 antibody (Cell Signaling Technologies, 2165) was used in western blot on human samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D8F12)
  • western blot; human
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 4290) was used in western blot on human samples . Cancer Res (2014) ncbi
mouse monoclonal (44E7)
  • western blot; human; 1:1000
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2248) was used in western blot on human samples at 1:1000. Front Endocrinol (Lausanne) (2014) ncbi
domestic rabbit monoclonal (29D8)
  • immunocytochemistry; human
  • western blot; human
In order to study the role of flotillin in the oncogenic effect of ErbB, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 29D8) was used in immunocytochemistry on human samples and in western blot on human samples . Biochim Biophys Acta (2014) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology Erbb2 antibody (Cell signaling, 2165) was used in western blot on human samples (fig 1a). Int J Oncol (2014) ncbi
domestic rabbit monoclonal (29D8)
  • western blot; human; fig 2
In order to study targeting sEcad for treatment of breast cancer, Cell Signaling Technology Erbb2 antibody (Cell Signaling, 2165) was used in western blot on human samples (fig 2). Mol Carcinog (2014) ncbi
domestic rabbit monoclonal (29D8)
  • immunocytochemistry; mouse; 1:200
  • western blot; mouse; 1:1000
Cell Signaling Technology Erbb2 antibody (Cell Signaling, 29D8) was used in immunocytochemistry on mouse samples at 1:200 and in western blot on mouse samples at 1:1000. Dev Biol (2013) ncbi
domestic rabbit monoclonal (29D8)
  • immunocytochemistry; human; 1:150
Cell Signaling Technology Erbb2 antibody (Cell Signaling Technology, 29D8) was used in immunocytochemistry on human samples at 1:150. Breast Cancer Res (2011) ncbi
Articles Reviewed
  1. Feng K, Meng P, Zhang M, Zou X, Li S, Huang C, et al. IL-24 Contributes to Neutrophilic Asthma in an IL-17A-Dependent Manner and Is Suppressed by IL-37. Allergy Asthma Immunol Res. 2022;14:505-527 pubmed publisher
  2. Marei H, Tsai W, Kee Y, Ruiz K, He J, Cox C, et al. Antibody targeting of E3 ubiquitin ligases for receptor degradation. Nature. 2022;610:182-189 pubmed publisher
  3. Shu W, Zhu X, Wang K, Cherepanoff S, Conway R, Madigan M, et al. The multi-kinase inhibitor afatinib serves as a novel candidate for the treatment of human uveal melanoma. Cell Oncol (Dordr). 2022;45:601-619 pubmed publisher
  4. Malanga D, Laudanna C, Mirante T, Colelli F, Migliozzi S, Zoppoli P, et al. The AKT1E17K Allele Promotes Breast Cancer in Mice. Cancers (Basel). 2022;14: pubmed publisher
  5. Wang Q, Bergholz J, Ding L, Lin Z, Kabraji S, Hughes M, et al. STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer. Nat Commun. 2022;13:3022 pubmed publisher
  6. Qin L, Wang L, Zhang J, Zhou H, Yang Z, Wang Y, et al. Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer. Sci Adv. 2022;8:eabn3774 pubmed publisher
  7. Chen Y, Xu J, Pan W, Xu X, Ma X, Chu Y, et al. Galectin-3 enhances trastuzumab resistance by regulating cancer malignancy and stemness in HER2-positive breast cancer cells. Thorac Cancer. 2022;13:1961-1973 pubmed publisher
  8. Dai J, Cimino P, Gouin K, Grzelak C, Barrett A, Lim A, et al. Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain. Nat Cancer. 2022;3:25-42 pubmed publisher
  9. Humeres C, Shinde A, Hanna A, Alex L, Hern xe1 ndez S, Li R, et al. Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure. J Clin Invest. 2022;132: pubmed publisher
  10. Khasawneh R, Kist R, Queen R, Hussain R, Coxhead J, Schneider J, et al. Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype. BMC Dev Biol. 2021;21:14 pubmed publisher
  11. Goyette M, Elkholi I, Apcher C, Kuasne H, Rothlin C, Muller W, et al. Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  12. Joh D, Heggestad J, Zhang S, Anderson G, Bhattacharyya J, Wardell S, et al. Cellphone enabled point-of-care assessment of breast tumor cytology and molecular HER2 expression from fine-needle aspirates. NPJ Breast Cancer. 2021;7:85 pubmed publisher
  13. Xie C, Ye F, Zhang N, Huang Y, Pan Y, Xie X. CCL7 contributes to angiotensin II-induced abdominal aortic aneurysm by promoting macrophage infiltration and pro-inflammatory phenotype. J Cell Mol Med. 2021;25:7280-7293 pubmed publisher
  14. Zhu J, Cai T, Zhou J, Du W, Zeng Y, Liu T, et al. CD151 drives cancer progression depending on integrin α3β1 through EGFR signaling in non-small cell lung cancer. J Exp Clin Cancer Res. 2021;40:192 pubmed publisher
  15. Wang J, Zhang Y, Xiao Y, Yuan X, Li P, Wang X, et al. Boosting immune surveillance by low-dose PI3K inhibitor facilitates early intervention of breast cancer. Am J Cancer Res. 2021;11:2005-2024 pubmed
  16. Kundumani Sridharan V, Subramani J, Owens C, Das K. Nrg1β Released in Remote Ischemic Preconditioning Improves Myocardial Perfusion and Decreases Ischemia/Reperfusion Injury via ErbB2-Mediated Rescue of Endothelial Nitric Oxide Synthase and Abrogation of Trx2 Autophagy. Arterioscler Thromb Vasc Biol. 2021;41:2293-2314 pubmed publisher
  17. Prokakis E, Dyas A, Grün R, Fritzsche S, Bedi U, Kazerouni Z, et al. USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response. Oncogene. 2021;40:4004-4018 pubmed publisher
  18. Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, et al. DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells. Theranostics. 2021;11:6355-6369 pubmed publisher
  19. Chen Y, Wang R, Huang S, Henson E, Bi J, Gibson S. Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher
  20. Yang Y, Leonard M, Luo Z, Yeo S, Bick G, Hao M, et al. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell Rep. 2021;34:108822 pubmed publisher
  21. Li W, Gu X, Liu C, Shi Y, Wang P, Zhang N, et al. A synergetic effect of BARD1 mutations on tumorigenesis. Nat Commun. 2021;12:1243 pubmed publisher
  22. Fu C, Zhang Q, Wang A, Yang S, Jiang Y, Bai L, et al. EWI-2 controls nucleocytoplasmic shuttling of EGFR signaling molecules and miRNA sorting in exosomes to inhibit prostate cancer cell metastasis. Mol Oncol. 2021;15:1543-1565 pubmed publisher
  23. Isomura H, Taguchi A, Kajino T, Asai N, Nakatochi M, Kato S, et al. Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator. Cancer Sci. 2021;: pubmed publisher
  24. Le T, Galmiche L, Levy J, Suwannarat P, Hellebrekers D, Morarach K, et al. Dysregulation of the NRG1/ERBB pathway causes a developmental disorder with gastrointestinal dysmotility in humans. J Clin Invest. 2021;131: pubmed publisher
  25. Miller K, Pniewski K, Perry C, Papp S, Shaffer J, Velasco Silva J, et al. Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth. Cancer Res. 2021;81:1252-1264 pubmed publisher
  26. Padthaisong S, Thanee M, Namwat N, Phetcharaburanin J, Klanrit P, Khuntikeo N, et al. A panel of protein kinase high expression is associated with postoperative recurrence in cholangiocarcinoma. BMC Cancer. 2020;20:154 pubmed publisher
  27. Liu Q, Borcherding N, Shao P, Maina P, Zhang W, Qi H. Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance. EBioMedicine. 2020;51:102612 pubmed publisher
  28. Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher
  29. Nagpal A, Redvers R, Ling X, Ayton S, Fuentes M, Tavancheh E, et al. Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ve breast cancer metastasis. Breast Cancer Res. 2019;21:94 pubmed publisher
  30. Kaya P, Lee S, Lee Y, Kwon S, Yang H, Lee H, et al. Curcumae Radix Extract Decreases Mammary Tumor-Derived Lung Metastasis via Suppression of C-C Chemokine Receptor Type 7 Expression. Nutrients. 2019;11: pubmed publisher
  31. Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed publisher
  32. Zhao H, Martin E, Matalkah F, Shah N, Ivanov A, Ruppert J, et al. Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis. Oncogene. 2019;38:2275-2290 pubmed publisher
  33. Xue Z, Vis D, Bruna A, Sustic T, van Wageningen S, Batra A, et al. MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models. Cell Res. 2018;28:719-729 pubmed publisher
  34. Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, et al. MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state. Nat Commun. 2018;9:1024 pubmed publisher
  35. Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández Mateos J, Khan K, et al. Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. Science. 2018;359:920-926 pubmed publisher
  36. Thaler S, Schmidt M, Roβwag S, Thiede G, Schad A, Sleeman J. Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells. Oncotarget. 2017;8:72281-72301 pubmed publisher
  37. Goel S, Decristo M, Watt A, BrinJones H, Sceneay J, Li B, et al. CDK4/6 inhibition triggers anti-tumour immunity. Nature. 2017;548:471-475 pubmed publisher
  38. Kwon S, Cho C, Kwon Y, Lee E, Park J. A Microfluidic Immunostaining System Enables Quality Assured and Standardized Immunohistochemical Biomarker Analysis. Sci Rep. 2017;7:45968 pubmed publisher
  39. Solis N, Swidergall M, Bruno V, Gaffen S, Filler S. The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis. MBio. 2017;8: pubmed publisher
  40. Seberg H, Van Otterloo E, Loftus S, Liu H, Bonde G, Sompallae R, et al. TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF. PLoS Genet. 2017;13:e1006636 pubmed publisher
  41. Schumacher M, Hedl M, Abraham C, Bernard J, Lozano P, Hsieh J, et al. ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation. Cell Death Dis. 2017;8:e2622 pubmed publisher
  42. Jin L, Chun J, Pan C, Alesi G, Li D, Magliocca K, et al. Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis. Oncogene. 2017;36:3797-3806 pubmed publisher
  43. Radder J, Zhang Y, Gregory A, Yu S, Kelly N, Leader J, et al. Extreme Trait Whole-Genome Sequencing Identifies PTPRO as a Novel Candidate Gene in Emphysema with Severe Airflow Obstruction. Am J Respir Crit Care Med. 2017;196:159-171 pubmed publisher
  44. Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, et al. Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway. Sci Rep. 2016;6:39557 pubmed publisher
  45. Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, et al. Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines. J Cancer Res Clin Oncol. 2017;143:573-600 pubmed publisher
  46. Torgersen M, Klokk T, Kavaliauskiene S, Klose C, Simons K, Skotland T, et al. The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget. 2016;7:86871-86888 pubmed publisher
  47. Mitra S, Ghosh B, Gayen N, Roy J, Mandal A. Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation. J Biol Chem. 2016;291:24579-24593 pubmed
  48. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  49. Jordan N, Bardia A, Wittner B, Benes C, Ligorio M, Zheng Y, et al. HER2 expression identifies dynamic functional states within circulating breast cancer cells. Nature. 2016;537:102-106 pubmed publisher
  50. LAW M, Ferreira R, Davis B, Higgins P, Kim J, Castellano R, et al. CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment. Breast Cancer Res. 2016;18:80 pubmed publisher
  51. Di Franco S, Turdo A, Benfante A, Colorito M, Gaggianesi M, Apuzzo T, et al. ?Np63 drives metastasis in breast cancer cells via PI3K/CD44v6 axis. Oncotarget. 2016;7:54157-54173 pubmed publisher
  52. Jiang Q, Chen S, Hu C, Huang P, Shen H, Zhao W. Neuregulin-1 (Nrg1) signaling has a preventive role and is altered in the frontal cortex under the pathological conditions of Alzheimer's disease. Mol Med Rep. 2016;14:2614-24 pubmed publisher
  53. Szymanska M, Fosdahl A, Nikolaysen F, Pedersen M, Grandal M, Stang E, et al. A combination of two antibodies recognizing non-overlapping epitopes of HER2 induces kinase activity-dependent internalization of HER2. J Cell Mol Med. 2016;20:1999-2011 pubmed publisher
  54. Merry C, McMahon S, Forrest M, Bartels C, Saiakhova A, Bartel C, et al. Transcriptome-wide identification of mRNAs and lincRNAs associated with trastuzumab-resistance in HER2-positive breast cancer. Oncotarget. 2016;7:53230-53244 pubmed publisher
  55. Saisana M, Griffin S, May F. Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation. Oncotarget. 2016;7:54445-54462 pubmed publisher
  56. Khan S, Sikander M, Ebeling M, Ganju A, Kumari S, Yallapu M, et al. MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression. Oncogene. 2017;36:491-500 pubmed publisher
  57. Yang Z, Jiang Q, Chen S, Hu C, Shen H, Huang P, et al. Differential changes in Neuregulin-1 signaling in major brain regions in a lipopolysaccharide-induced neuroinflammation mouse model. Mol Med Rep. 2016;14:790-6 pubmed publisher
  58. Yard B, Adams D, Chie E, Tamayo P, Battaglia J, Gopal P, et al. A genetic basis for the variation in the vulnerability of cancer to DNA damage. Nat Commun. 2016;7:11428 pubmed publisher
  59. Papadakis E, Barker C, Syed H, Reeves T, Schwaiger S, Stuppner H, et al. The Bag-1 inhibitor, Thio-2, reverses an atypical 3D morphology driven by Bag-1L overexpression in a MCF-10A model of ductal carcinoma in situ. Oncogenesis. 2016;5:e215 pubmed publisher
  60. Gschweitl M, Ulbricht A, Barnes C, Enchev R, Stoffel Studer I, Meyer Schaller N, et al. A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes. elife. 2016;5:e13841 pubmed publisher
  61. Mancini M, Lien E, Toker A. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis. Oncotarget. 2016;7:17301-13 pubmed publisher
  62. Meng Y, Zheng L, Yang Y, Wang H, Dong J, Wang C, et al. A monoclonal antibody targeting ErbB2 domain III inhibits ErbB2 signaling and suppresses the growth of ErbB2-overexpressing breast tumors. Oncogenesis. 2016;5:e211 pubmed publisher
  63. Stindt S, Cebula P, Albrecht U, Keitel V, Schulte Am Esch J, Knoefel W, et al. Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family. PLoS ONE. 2016;11:e0148711 pubmed publisher
  64. Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed publisher
  65. Khalil H, Langdon S, Kankia I, Bown J, Deeni Y. NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies. Oxid Med Cell Longev. 2016;2016:4148791 pubmed publisher
  66. Yamaguchi T, Lu C, Ida L, Yanagisawa K, Usukura J, Cheng J, et al. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. Nat Commun. 2016;7:10060 pubmed publisher
  67. Creedon H, Balderstone L, Muir M, Balla J, Gómez Cuadrado L, Tracey N, et al. Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer. Dis Model Mech. 2016;9:131-40 pubmed publisher
  68. Clemente Vicario F, Alvarez C, ROWELL J, Roy S, London C, Kisseberth W, et al. Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines. PLoS ONE. 2015;10:e0142007 pubmed publisher
  69. Askoxylakis V, Ferraro G, Kodack D, Badeaux M, Shankaraiah R, Seano G, et al. Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. J Natl Cancer Inst. 2016;108: pubmed publisher
  70. Pai P, Rachagani S, Lakshmanan I, Macha M, Sheinin Y, Smith L, et al. The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Mol Oncol. 2016;10:224-39 pubmed publisher
  71. Rodríguez C, Reidel S, Bal de Kier Joffé E, Jasnis M, Fiszman G. Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids. PLoS ONE. 2015;10:e0137920 pubmed publisher
  72. Capparelli C, Rosenbaum S, Berger A, Aplin A. Fibroblast-derived neuregulin 1 promotes compensatory ErbB3 receptor signaling in mutant BRAF melanoma. J Biol Chem. 2015;290:24267-77 pubmed publisher
  73. Wang D, Pang Z, Clarke G, Nofech Mozes S, Liu K, Cheung A, et al. Ki-67 Membranous Staining: Biologically Relevant or an Artifact of Multiplexed Immunofluorescent Staining. Appl Immunohistochem Mol Morphol. 2016;24:447-52 pubmed publisher
  74. Leung K, Batey S, Rowlands R, Isaac S, Jones P, Drewett V, et al. A HER2-specific Modified Fc Fragment (Fcab) Induces Antitumor Effects Through Degradation of HER2 and Apoptosis. Mol Ther. 2015;23:1722-1733 pubmed publisher
  75. Hagrass H, Sharaf S, Pasha H, Tantawy E, Mohamed R, Kassem R. Circulating microRNAs - a new horizon in molecular diagnosis of breast cancer. Genes Cancer. 2015;6:281-7 pubmed
  76. Blancafort A, Giró Perafita A, Oliveras G, Palomeras S, Turrado C, Campuzano Ã, et al. Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs. PLoS ONE. 2015;10:e0131241 pubmed publisher
  77. Yang L, Li Y, Bhattacharya A, Zhang Y. Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant. EBioMedicine. 2015;2:396-405 pubmed
  78. Jäger W, Xue H, Hayashi T, Janssen C, Awrey S, Wyatt A, et al. Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies. Oncotarget. 2015;6:21522-32 pubmed
  79. Hofmann B, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, et al. COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer. Mol Cancer. 2015;14:109 pubmed publisher
  80. Deleyrolle L, Sabourin J, Rothhut B, Fujita H, Guichet P, Teigell M, et al. OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor. PLoS ONE. 2015;10:e0122337 pubmed publisher
  81. Ferreira R, Law M, Jahn S, Davis B, Heldermon C, Reinhard M, et al. Novel agents that downregulate EGFR, HER2, and HER3 in parallel. Oncotarget. 2015;6:10445-59 pubmed
  82. Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed publisher
  83. Hu S, Sun Y, Meng Y, Wang X, Yang W, Fu W, et al. Molecular architecture of the ErbB2 extracellular domain homodimer. Oncotarget. 2015;6:1695-706 pubmed
  84. Yoo J, Kim T, Kong S, Lee J, Choi W, Kim K, et al. Role of Mig-6 in hepatic glucose metabolism. J Diabetes. 2016;8:86-97 pubmed publisher
  85. Blanchard Z, Paul B, Craft B, ElShamy W. BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers. Breast Cancer Res. 2015;17:5 pubmed publisher
  86. Kumar S, Das S, Rachagani S, Kaur S, Joshi S, Johansson S, et al. NCOA3-mediated upregulation of mucin expression via transcriptional and post-translational changes during the development of pancreatic cancer. Oncogene. 2015;34:4879-89 pubmed publisher
  87. Katz Y, Li F, Lambert N, Sokol E, Tam W, Cheng A, et al. Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state. elife. 2014;3:e03915 pubmed publisher
  88. Hong Y, Kim J, Pectasides E, Fox C, Hong S, Ma Q, et al. Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models. PLoS ONE. 2014;9:e109440 pubmed publisher
  89. Kugel C, Hartsough E, Davies M, Setiady Y, Aplin A. Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor. Cancer Res. 2014;74:4122-32 pubmed publisher
  90. Zeng L, Holly J, Perks C. Effects of physiological levels of the green tea extract epigallocatechin-3-gallate on breast cancer cells. Front Endocrinol (Lausanne). 2014;5:61 pubmed publisher
  91. Jung S, Ohk J, Jeong D, Li C, Lee S, Duan J, et al. Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells. Int J Oncol. 2014;45:189-96 pubmed publisher
  92. Asp N, Pust S, Sandvig K. Flotillin depletion affects ErbB protein levels in different human breast cancer cells. Biochim Biophys Acta. 2014;1843:1987-96 pubmed publisher
  93. Neumeister V, Parisi F, England A, Siddiqui S, Anagnostou V, Zarrella E, et al. A tissue quality index: an intrinsic control for measurement of effects of preanalytical variables on FFPE tissue. Lab Invest. 2014;94:467-74 pubmed publisher
  94. Xia Q, Cai Y, Peng R, Wu G, Shi Y, Jiang W. The CDK1 inhibitor RO3306 improves the response of BRCA-pro?cient breast cancer cells to PARP inhibition. Int J Oncol. 2014;44:735-44 pubmed publisher
  95. Brouxhon S, Kyrkanides S, Teng X, O Banion M, Clarke R, Byers S, et al. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers. Mol Carcinog. 2014;53:893-906 pubmed publisher
  96. Harmelink C, Peng Y, Debenedittis P, Chen H, Shou W, Jiao K. Myocardial Mycn is essential for mouse ventricular wall morphogenesis. Dev Biol. 2013;373:53-63 pubmed publisher
  97. Lindberg K, Helguero L, Omoto Y, Gustafsson J, Haldosén L. Estrogen receptor ? represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity. Breast Cancer Res. 2011;13:R43 pubmed publisher