This is a Validated Antibody Database (VAD) review about rat Epac, based on 5 published articles (read how Labome selects the articles), using Epac antibody in all methods. It is aimed to help Labome visitors find the most suited Epac antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Epac synonym: Epac; rap guanine nucleotide exchange factor 3; Rap guanine nucleotide exchange factor (GEF) 3; cAMP-GEFI; cAMP-regulated guanine nucleotide exchange factor I (cAMP-GEFI); epac 1; exchange factor directly activated by cAMP 1; exchange protein directly activated by cAMP 1

Abcam
rabbit monoclonal (EPR1672)
  • western blot; human; fig 1a
Abcam Epac antibody (Abcam, ab109415) was used in western blot on human samples (fig 1a). Mol Vis (2017) ncbi
rabbit polyclonal
  • western blot; rat
Abcam Epac antibody (Abcam, ab21236) was used in western blot on rat samples . Toxicol Pathol (2014) ncbi
rabbit monoclonal (EPR1672)
  • western blot; mouse; fig 1
Abcam Epac antibody (Abcam, ab109415) was used in western blot on mouse samples (fig 1). Diabetes (2013) ncbi
Cell Signaling Technology
mouse monoclonal (5D3)
  • western blot; human; loading ...; fig 4c
In order to study the expression of transmembrane AC isoforms in pancreatic cancer cells, Cell Signaling Technology Epac antibody (Cell Signaling, 4155) was used in western blot on human samples (fig 4c). Mol Carcinog (2017) ncbi
mouse monoclonal (5D3)
  • western blot; human; 1:2000; fig 6a
Cell Signaling Technology Epac antibody (Cell Signaling Technology, 5D3) was used in western blot on human samples at 1:2000 (fig 6a). Endocrinology (2014) ncbi
Articles Reviewed
  1. Liu L, Jiang Y, Chahine A, Curtiss E, Steinle J. Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice. Mol Vis. 2017;23:1-7 pubmed
  2. Quinn S, Graves S, Dains McGahee C, Friedman E, Hassan H, Witkowski P, et al. Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells. Mol Carcinog. 2017;56:1344-1360 pubmed publisher
  3. Tobin G, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, et al. The role of eNOS phosphorylation in causing drug-induced vascular injury. Toxicol Pathol. 2014;42:709-24 pubmed publisher
  4. Kusama K, Yoshie M, Tamura K, Nakayama T, Nishi H, Isaka K, et al. The role of exchange protein directly activated by cyclic AMP 2-mediated calreticulin expression in the decidualization of human endometrial stromal cells. Endocrinology. 2014;155:240-8 pubmed publisher
  5. Song W, Mondal P, Li Y, Lee S, Hussain M. Pancreatic ?-cell response to increased metabolic demand and to pharmacologic secretagogues requires EPAC2A. Diabetes. 2013;62:2796-807 pubmed publisher