This is a Validated Antibody Database (VAD) review about rat Ep300, based on 29 published articles (read how Labome selects the articles), using Ep300 antibody in all methods. It is aimed to help Labome visitors find the most suited Ep300 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
domestic rabbit monoclonal (EPR23495-268)
  • western blot; mouse; loading ...; fig 4d
Abcam Ep300 antibody (Abcam, ab275378) was used in western blot on mouse samples (fig 4d). Front Immunol (2022) ncbi
mouse monoclonal (3G230 / NM-11)
  • chromatin immunoprecipitation; human; loading ...; fig 7b
Abcam Ep300 antibody (Abcam, ab14984) was used in chromatin immunoprecipitation on human samples (fig 7b). Cell Death Dis (2021) ncbi
mouse monoclonal (3G230 / NM-11)
  • chromatin immunoprecipitation; mouse; loading ...; fig 6c
Abcam Ep300 antibody (Abcam, ab14984) was used in chromatin immunoprecipitation on mouse samples (fig 6c). Acta Neuropathol Commun (2021) ncbi
domestic rabbit monoclonal (EPR23495-268)
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
  • chromatin immunoprecipitation; human; loading ...; fig 4k
  • western blot; human; loading ...; fig 4h
Abcam Ep300 antibody (Abcam, ab275378) was used in immunohistochemistry - paraffin section on human samples (fig 6a), in chromatin immunoprecipitation on human samples (fig 4k) and in western blot on human samples (fig 4h). Clin Transl Med (2021) ncbi
mouse monoclonal (3G230 / NM-11)
  • western blot; human; loading ...; fig 3b
Abcam Ep300 antibody (Abcam, ab14984) was used in western blot on human samples (fig 3b). Signal Transduct Target Ther (2021) ncbi
mouse monoclonal (3G230 / NM-11)
  • other; human; 1:1000; loading ...; fig 4j
Abcam Ep300 antibody (Abcam, Ab14984) was used in other on human samples at 1:1000 (fig 4j). elife (2020) ncbi
mouse monoclonal (3G230 / NM-11)
  • ChIP-Seq; mouse; loading ...
Abcam Ep300 antibody (Abcam, ab14984) was used in ChIP-Seq on mouse samples . Science (2020) ncbi
mouse monoclonal (3G230 / NM-11)
  • chromatin immunoprecipitation; mouse; loading ...; fig e6b
Abcam Ep300 antibody (Abcam, ab14984) was used in chromatin immunoprecipitation on mouse samples (fig e6b). Nature (2019) ncbi
mouse monoclonal (3G230 / NM-11)
  • chromatin immunoprecipitation; human; loading ...; fig 6a
Abcam Ep300 antibody (abcam, ab14984) was used in chromatin immunoprecipitation on human samples (fig 6a). Sci Rep (2019) ncbi
mouse monoclonal (3G230 / NM-11)
  • ChIP-Seq; human; fig 4g
Abcam Ep300 antibody (Abcam, ab14984) was used in ChIP-Seq on human samples (fig 4g). Nat Commun (2017) ncbi
mouse monoclonal (3G230 / NM-11)
  • chromatin immunoprecipitation; human; loading ...; fig 5g
Abcam Ep300 antibody (Abcam, ab14984) was used in chromatin immunoprecipitation on human samples (fig 5g). PLoS Genet (2015) ncbi
mouse monoclonal (3G230 / NM-11)
  • chromatin immunoprecipitation; human
Abcam Ep300 antibody (Abcam, ab-14984) was used in chromatin immunoprecipitation on human samples . Nucleic Acids Res (2014) ncbi
mouse monoclonal (3G230 / NM-11)
  • chromatin immunoprecipitation; human
Abcam Ep300 antibody (Abcam, ab14984) was used in chromatin immunoprecipitation on human samples . BMC Cancer (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-4)
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig 6b
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-48343) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig 6b). Histochem Cell Biol (2021) ncbi
mouse monoclonal (NM11)
  • immunohistochemistry; mouse; loading ...; fig 4d
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, sc-32244) was used in immunohistochemistry on mouse samples (fig 4d). Cell Rep (2020) ncbi
mouse monoclonal (SPM307)
  • immunoprecipitation; mouse; loading ...; fig 5l
  • western blot; mouse; loading ...; fig 5l
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-56455) was used in immunoprecipitation on mouse samples (fig 5l) and in western blot on mouse samples (fig 5l). Sci Adv (2019) ncbi
mouse monoclonal (NM11)
  • western blot; human; 1:500; loading ...; fig s11a
Santa Cruz Biotechnology Ep300 antibody (Santa, sc-32244) was used in western blot on human samples at 1:500 (fig s11a). Nat Commun (2019) ncbi
mouse monoclonal (F-4)
  • immunoprecipitation; human; loading ...; fig 7b
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology Inc, sc-48343) was used in immunoprecipitation on human samples (fig 7b). Nucleic Acids Res (2018) ncbi
mouse monoclonal (NM11)
  • western blot; human; loading ...; fig 6d
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, SC-32244) was used in western blot on human samples (fig 6d). J Exp Med (2018) ncbi
mouse monoclonal (F-4)
  • chromatin immunoprecipitation; human; fig 2h
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-48343X) was used in chromatin immunoprecipitation on human samples (fig 2h). Cancer Res (2018) ncbi
mouse monoclonal (F-4)
  • proximity ligation assay; mouse; fig 3f
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-48343) was used in proximity ligation assay on mouse samples (fig 3f). Nat Commun (2015) ncbi
mouse monoclonal (F-4)
  • chromatin immunoprecipitation; rat; fig  6
  • western blot; rat; 1:1000; fig 8
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, sc-48343) was used in chromatin immunoprecipitation on rat samples (fig  6) and in western blot on rat samples at 1:1000 (fig 8). J Neurosci (2015) ncbi
mouse monoclonal (NM11)
  • chromatin immunoprecipitation; African green monkey
  • western blot; African green monkey
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, sc-32244) was used in chromatin immunoprecipitation on African green monkey samples and in western blot on African green monkey samples . J Biol Chem (2014) ncbi
mouse monoclonal (F-4)
  • western blot; human
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, sc-48343) was used in western blot on human samples . PLoS ONE (2012) ncbi
mouse monoclonal (NM11)
  • immunohistochemistry - paraffin section; rat; 1:300
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-32244) was used in immunohistochemistry - paraffin section on rat samples at 1:300. Cell Mol Neurobiol (2013) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6a
Invitrogen Ep300 antibody (ThermoFisher, PA5-64531) was used in western blot on human samples at 1:1000 (fig 6a). Nat Commun (2019) ncbi
mouse monoclonal (RW105)
  • chromatin immunoprecipitation; human; loading ...; fig 5e
In order to assess the effect of TNF-alpha inhibitors on monocyte chemoattractant protein-1, Invitrogen Ep300 antibody (Thermo Fisher, MA1-16622) was used in chromatin immunoprecipitation on human samples (fig 5e). Mol Immunol (2017) ncbi
mouse monoclonal (RW105)
  • western blot; human
In order to study mechanisms of microtubule hyperacetylation, Invitrogen Ep300 antibody (Pierce Biotechnology, MA1-16622) was used in western blot on human samples . J Biol Chem (2014) ncbi
Novus Biologicals
domestic rabbit polyclonal (1F11)
  • immunoprecipitation; human; fig 12
  • western blot; human; fig 12
In order to determine how prolonged hypoxia conditions are negative regulators of hypoxia-inducible factors by PRDX2 and PRDX4, Novus Biologicals Ep300 antibody (Novus Biologicals, NB500-161) was used in immunoprecipitation on human samples (fig 12) and in western blot on human samples (fig 12). Oncotarget (2016) ncbi
Articles Reviewed
  1. Leng S, Zhang X, Wang S, Qin J, Liu Q, Liu A, et al. Ion channel Piezo1 activation promotes aerobic glycolysis in macrophages. Front Immunol. 2022;13:976482 pubmed publisher
  2. Chen D, Zhao Z, Chen L, Li Q, Zou J, Liu S. PPM1G promotes the progression of hepatocellular carcinoma via phosphorylation regulation of alternative splicing protein SRSF3. Cell Death Dis. 2021;12:722 pubmed publisher
  3. Liu X, Wang Q, Yang Y, Stewart T, Shi M, Soltys D, et al. Reduced erythrocytic CHCHD2 mRNA is associated with brain pathology of Parkinson's disease. Acta Neuropathol Commun. 2021;9:37 pubmed publisher
  4. Zhang C, Lu X, Huang J, He H, Chen L, Liu Y, et al. Epigenome screening highlights that JMJD6 confers an epigenetic vulnerability and mediates sunitinib sensitivity in renal cell carcinoma. Clin Transl Med. 2021;11:e328 pubmed publisher
  5. Huang Y, Cai K, Xu P, Wang L, Huang C, Fang Y, et al. CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis. Signal Transduct Target Ther. 2021;6:10 pubmed publisher
  6. Du A, Li L, Jiao Z, Zhu G, Peng T, Li H. Protein expression pattern of calcium-responsive transactivator in early postnatal and adult testes. Histochem Cell Biol. 2021;155:491-502 pubmed publisher
  7. Pal A, Leung J, Ang G, Rao V, Pignata L, Lim H, et al. EHMT2 epigenetically suppresses Wnt signaling and is a potential target in embryonal rhabdomyosarcoma. elife. 2020;9: pubmed publisher
  8. Wilson M, Reske J, Holladay J, Neupane S, Ngo J, Cuthrell N, et al. ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. Cell Rep. 2020;33:108366 pubmed publisher
  9. Liu J, Dou X, Chen C, Chen C, Liu C, Xu M, et al. N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription. Science. 2020;367:580-586 pubmed publisher
  10. Hang S, Paik D, Yao L, Kim E, Jamma T, Lu J, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019;576:143-148 pubmed publisher
  11. Miyazaki T, Zhao Z, Ichihara Y, Yoshino D, Imamura T, Sawada K, et al. Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity. Sci Adv. 2019;5:eaau7802 pubmed publisher
  12. Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, et al. Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. Nat Commun. 2019;10:2229 pubmed publisher
  13. Lee J, Chang J, Dominguez A, Lee H, Nam S, Chang J, et al. YAP-independent mechanotransduction drives breast cancer progression. Nat Commun. 2019;10:1848 pubmed publisher
  14. Tsai C, Tsai C, Yi J, Kao H, Huang Y, Wang C, et al. Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells. Sci Rep. 2019;9:5197 pubmed publisher
  15. Bao J, Rousseaux S, Shen J, Lin K, Lu Y, Bedford M. The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis. Nucleic Acids Res. 2018;46:4327-4343 pubmed publisher
  16. Xiao X, Fan Y, Li J, Zhang X, Lou X, Dou Y, et al. Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation. J Exp Med. 2018;215:559-574 pubmed publisher
  17. Wu Y, Zhang Z, Cenciarini M, Proietti C, Amasino M, Hong T, et al. Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERα-GREB1 Transcriptional Axis. Cancer Res. 2018;78:671-684 pubmed publisher
  18. Monteagudo S, Cornelis F, Aznar López C, Yibmantasiri P, Guns L, Carmeliet P, et al. DOT1L safeguards cartilage homeostasis and protects against osteoarthritis. Nat Commun. 2017;8:15889 pubmed publisher
  19. Lin Y, Lin Y, Huang M, Kuo P, Wu C, Lee M, et al. Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification. Mol Immunol. 2017;83:82-91 pubmed publisher
  20. Luo W, Chen I, Chen Y, Alkam D, Wang Y, Semenza G. PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia. Oncotarget. 2016;7:6379-97 pubmed publisher
  21. Stein C, Bardet A, Roma G, Bergling S, Clay I, Ruchti A, et al. YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers. PLoS Genet. 2015;11:e1005465 pubmed publisher
  22. Yoon J, Sudo K, Kuroda M, Kato M, Lee I, Han J, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nat Commun. 2015;6:7600 pubmed publisher
  23. Formisano L, Guida N, Valsecchi V, Cantile M, Cuomo O, Vinciguerra A, et al. Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism. J Neurosci. 2015;35:7332-48 pubmed publisher
  24. Moquet Torcy G, Tolza C, Piechaczyk M, Jariel Encontre I. Transcriptional complexity and roles of Fra-1/AP-1 at the uPA/Plau locus in aggressive breast cancer. Nucleic Acids Res. 2014;42:11011-24 pubmed publisher
  25. Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed publisher
  26. Wehmeyer L, Du Toit A, Lang D, Hapgood J. Lipid raft- and protein kinase C-mediated synergism between glucocorticoid- and gonadotropin-releasing hormone signaling results in decreased cell proliferation. J Biol Chem. 2014;289:10235-51 pubmed publisher
  27. Wagner M, Koslowski M, Paret C, Schmidt M, Tureci O, Sahin U. NCOA3 is a selective co-activator of estrogen receptor ?-mediated transactivation of PLAC1 in MCF-7 breast cancer cells. BMC Cancer. 2013;13:570 pubmed publisher
  28. Ogiwara H, Kohno T. CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes. PLoS ONE. 2012;7:e52810 pubmed publisher
  29. Zhu X, Huang C, Li Q, Guo Q, Wang Y, He X, et al. Temporal distribution of p300/CBP immunoreactivity in the adult rat spinal dorsal horn following chronic constriction injury (CCI). Cell Mol Neurobiol. 2013;33:197-204 pubmed publisher