This is a Validated Antibody Database (VAD) review about rat Eif4g1, based on 29 published articles (read how Labome selects the articles), using Eif4g1 antibody in all methods. It is aimed to help Labome visitors find the most suited Eif4g1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Eif4g1 synonym: eukaryotic translation initiation factor 4 gamma 1; voltage-dependent P/Q-type calcium channel subunit alpha-1A-like

Santa Cruz Biotechnology
mouse monoclonal (A-10)
  • western blot; human; 1:1000; loading ...; fig 4d
Santa Cruz Biotechnology Eif4g1 antibody (Santa Cruz, sc-133155) was used in western blot on human samples at 1:1000 (fig 4d). Nat Commun (2017) ncbi
mouse monoclonal (A-10)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology Eif4g1 antibody (SantaCruz, sc-133155) was used in immunohistochemistry - paraffin section on human samples (fig 1) and in western blot on human samples (fig 2a). Exp Neurol (2018) ncbi
mouse monoclonal (H-2)
  • western blot; human; 1:500; fig 8
Santa Cruz Biotechnology Eif4g1 antibody (Santa Cruz, sc-373892) was used in western blot on human samples at 1:500 (fig 8). BMC Mol Biol (2016) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:500; fig 3
Abcam Eif4g1 antibody (Abcam, ab2609) was used in western blot on human samples at 1:500 (fig 3). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 2
Abcam Eif4g1 antibody (Abcam, ab2609) was used in western blot on mouse samples at 1:1000 (fig 2). elife (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Abcam Eif4g1 antibody (Abcam, ab2609) was used in western blot on human samples (fig 1). Cancer Discov (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100
Abcam Eif4g1 antibody (Abcam, ab2609) was used in immunohistochemistry - paraffin section on human samples at 1:100. Acta Neuropathol (2013) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human; loading ...; fig 9
Proteintech Group Eif4g1 antibody (Proteintech, 15704-1-AP) was used in western blot on human samples (fig 9). PLoS Genet (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000
Proteintech Group Eif4g1 antibody (Proteintech, 15704-1-AP) was used in western blot on human samples at 1:1000. Virol J (2014) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1b
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2498) was used in western blot on human samples at 1:1000 (fig 1b). Int J Biol Sci (2019) ncbi
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2498) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit monoclonal (C45A4)
  • immunohistochemistry; human; loading ...; fig 3c
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2469S) was used in immunohistochemistry on human samples (fig 3c) and in western blot on human samples (fig 2a). PLoS Pathog (2018) ncbi
rabbit monoclonal (D6A6)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1c
  • immunocytochemistry; mouse; 1:100; loading ...; fig 3b
  • western blot; mouse; 1:3000; loading ...; fig 1b
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 8701S) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 1c), in immunocytochemistry on mouse samples at 1:100 (fig 3b) and in western blot on mouse samples at 1:3000 (fig 1b). Biol Reprod (2018) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 3f
Cell Signaling Technology Eif4g1 antibody (Cell Signaling Technology, 2858) was used in western blot on mouse samples (fig 3f). Cancer Res (2017) ncbi
rabbit monoclonal (C45A4)
  • western blot; mouse; loading ...; fig 3b
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, C45A4) was used in western blot on mouse samples (fig 3b). Cell Death Differ (2017) ncbi
rabbit polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology Eif4g1 antibody (CST, 2498) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
rabbit monoclonal (C45A4)
  • western blot; mouse; loading ...; fig s1a
In order to study the role of Yin-yang 2 in mouse embryonic stem cells, Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2469) was used in western blot on mouse samples (fig s1a). Proc Natl Acad Sci U S A (2016) ncbi
rabbit monoclonal (C45A4)
  • western blot; mouse; loading ...; fig s3d
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2469) was used in western blot on mouse samples (fig s3d). Cell Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1b
In order to identify a cap-dependent translation mechanism that is independent of eIF4E, Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2858) was used in western blot on human samples (fig 1b). Nature (2016) ncbi
rabbit polyclonal
  • western blot; fruit fly; fig s1
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2498) was used in western blot on fruit fly samples (fig s1). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4d
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2498) was used in western blot on human samples (fig 4d). Mol Cell (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 7
Cell Signaling Technology Eif4g1 antibody (Cell Signaling Technology, 2498) was used in western blot on human samples (fig 7). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig s1
Cell Signaling Technology Eif4g1 antibody (Cell Signaling Technologies, 2858) was used in western blot on human samples at 1:1000 (fig s1). Nat Commun (2016) ncbi
rabbit monoclonal (C45A4)
  • western blot; human; fig 4
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2469S) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2441S) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
rabbit polyclonal
  • other; mouse; 1:1000; fig s1
In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2498) was used in other on mouse samples at 1:1000 (fig s1). Front Microbiol (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology Eif4g1 antibody (Cell Signaling Tech, 2858) was used in western blot on mouse samples at 1:1000 (fig 6). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 7
Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2498) was used in western blot on human samples at 1:1000 (fig 7). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Eif4g1 antibody (Cell Signaling Technology, 2498) was used in western blot on human samples . Mol Cell Biol (2014) ncbi
rabbit polyclonal
  • western blot; human; fig s4
In order to study the role of loss of spliceosome integrity in the development of amyotrophic lateral sclerosis and spinal muscular atrophy, Cell Signaling Technology Eif4g1 antibody (Cell Signaling, 2498) was used in western blot on human samples (fig s4). EMBO Mol Med (2013) ncbi
Articles Reviewed
  1. Wang H, Huang F, Zhang Z, Wang P, Luo Y, Li H, et al. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer. Int J Biol Sci. 2019;15:929-941 pubmed publisher
  2. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  3. Yang X, Hu Z, Fan S, Zhang Q, Zhong Y, Guo D, et al. Picornavirus 2A protease regulates stress granule formation to facilitate viral translation. PLoS Pathog. 2018;14:e1006901 pubmed publisher
  4. Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed publisher
  5. Hu J, Sun F, Handel M. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018;98:102-114 pubmed publisher
  6. Hsu J, Hubbell Engler B, Adelmant G, Huang J, Joyce C, Vazquez F, et al. PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer. Cancer Res. 2017;77:4613-4625 pubmed publisher
  7. Lingel H, Wissing J, Arra A, Schanze D, Lienenklaus S, Klawonn F, et al. CTLA-4-mediated posttranslational modifications direct cytotoxic T-lymphocyte differentiation. Cell Death Differ. 2017;24:1739-1749 pubmed publisher
  8. Oblinger J, Burns S, Huang J, Pan L, Ren Y, Shen R, et al. Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation. Exp Neurol. 2018;299:299-307 pubmed publisher
  9. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  10. Tahmasebi S, Jafarnejad S, Tam I, Gonatopoulos Pournatzis T, Matta Camacho E, Tsukumo Y, et al. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proc Natl Acad Sci U S A. 2016;113:12360-12367 pubmed
  11. Frydryskova K, Masek T, Borcin K, Mrvova S, Venturi V, Pospisek M. Distinct recruitment of human eIF4E isoforms to processing bodies and stress granules. BMC Mol Biol. 2016;17:21 pubmed publisher
  12. Tsai S, Rodriguez A, Dastidar S, Del Greco E, Carr K, Sitzmann J, et al. Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice. Cell Rep. 2016;16:1903-14 pubmed publisher
  13. Lee A, Kranzusch P, Doudna J, Cate J. eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature. 2016;536:96-9 pubmed
  14. Penney J, Tsurudome K, Liao E, Kauwe G, Gray L, Yanagiya A, et al. LRRK2 regulates retrograde synaptic compensation at the Drosophila neuromuscular junction. Nat Commun. 2016;7:12188 pubmed publisher
  15. Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed publisher
  16. Lin S, Choe J, Du P, Triboulet R, Gregory R. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016;62:335-345 pubmed publisher
  17. Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed publisher
  18. Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  19. Lyabin D, Ovchinnikov L. Selective regulation of YB-1 mRNA translation by the mTOR signaling pathway is not mediated by 4E-binding protein. Sci Rep. 2016;6:22502 pubmed publisher
  20. Khoutorsky A, Bonin R, Sorge R, Gkogkas C, Pawlowski S, Jafarnejad S, et al. Translational control of nociception via 4E-binding protein 1. elife. 2015;4: pubmed publisher
  21. Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  22. Hu S, Li J, Xu F, Mei S, Le Duff Y, Yin L, et al. SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation. PLoS Genet. 2015;11:e1005367 pubmed publisher
  23. Sato M, Matsubara T, Adachi J, Hashimoto Y, Fukamizu K, Kishida M, et al. Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model. PLoS ONE. 2015;10:e0126483 pubmed publisher
  24. Martínez A, Sesé M, Losa J, Robichaud N, Sonenberg N, Aasen T, et al. Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. PLoS ONE. 2015;10:e0123352 pubmed publisher
  25. Van Rechem C, Black J, Boukhali M, Aryee M, Gräslund S, Haas W, et al. Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis. Cancer Discov. 2015;5:255-63 pubmed publisher
  26. Wu S, Wang Y, Lin L, Si X, Wang T, Zhong X, et al. Protease 2A induces stress granule formation during coxsackievirus B3 and enterovirus 71 infections. Virol J. 2014;11:192 pubmed publisher
  27. Cen B, Xiong Y, Song J, Mahajan S, DuPont R, McEachern K, et al. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014;34:2517-32 pubmed publisher
  28. Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, et al. Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. EMBO Mol Med. 2013;5:221-34 pubmed publisher
  29. Fujioka S, Sundal C, Strongosky A, Castanedes M, Rademakers R, Ross O, et al. Sequence variants in eukaryotic translation initiation factor 4-gamma (eIF4G1) are associated with Lewy body dementia. Acta Neuropathol. 2013;125:425-38 pubmed publisher