This is a Validated Antibody Database (VAD) review about rat Eif2ak3, based on 83 published articles (read how Labome selects the articles), using Eif2ak3 antibody in all methods. It is aimed to help Labome visitors find the most suited Eif2ak3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Eif2ak3 synonym: PEK

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; 1:500; fig 6d
In order to examine the impact of the unfolded protein response in satellite cell homeostasis during regenerative myogenesis, Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3192) was used in western blot knockout validation on mouse samples at 1:500 (fig 6d). elife (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; loading ...; fig 2b
Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3192) was used in western blot knockout validation on mouse samples (fig 2b). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; fig 5
In order to test if suppressing eIF2alpha kinases alleviates synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot knockout validation on mouse samples (fig 5). Nat Neurosci (2013) ncbi
Invitrogen
domestic rabbit monoclonal (G.305.4)
  • western blot; human; fig 3f
In order to study the effect of mesencephalic astrocyte-derived neurotrophic factor on apoptosis and its mechanism, Invitrogen Eif2ak3 antibody (Thermo Fisher, MA5-15033) was used in western blot on human samples (fig 3f). Transl Neurodegener (2017) ncbi
domestic rabbit monoclonal (G.305.4)
  • western blot; human; fig 4
In order to determine the induction of transforming growth factor beta1 through activation of endoplasmic reticulum stress and the unfolded protein response due to HCV, Invitrogen Eif2ak3 antibody (Thermo Scientific, MA5-15033) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
domestic rabbit monoclonal (G.305.4)
  • western blot; mouse; 1:1000; fig 6e
In order to examine the role of the host unfolded protein response during L. pneumophila infection, Invitrogen Eif2ak3 antibody (Thermo, MA5-15033) was used in western blot on mouse samples at 1:1000 (fig 6e). Nat Commun (2015) ncbi
domestic rabbit monoclonal (G.305.4)
  • western blot; mouse; 1:1000; fig 6e
In order to study the function of PTPRR and PTPRZ1 proteins in oral cavity squamous cell carcinoma, Invitrogen Eif2ak3 antibody (Thermo, MA5-15033) was used in western blot on mouse samples at 1:1000 (fig 6e). Head Neck (2015) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig s4e
Abcam Eif2ak3 antibody (Abcam, ab217322) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig s4e). Cell (2019) ncbi
domestic rabbit polyclonal
Abcam Eif2ak3 antibody (Abcam, ab192591) was used . EMBO Mol Med (2019) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
MilliporeSigma Eif2ak3 antibody (Sigma, P0074) was used in western blot on mouse samples (fig 2a). Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 9e
MilliporeSigma Eif2ak3 antibody (Sigma-Aldrich, P0074) was used in western blot on mouse samples at 1:1000 (fig 9e). Nat Commun (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig s4c
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples at 1:1000 (fig s4c). Science (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 5f
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 5f). Cell (2019) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; loading ...; fig 5f
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples (fig 5f). Cell (2019) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; loading ...; fig 2a
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples (fig 2a). Cell (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology Eif2ak3 antibody (CST, 3192) was used in western blot on mouse samples (fig 5a). Cell (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 2b
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 2b). Nature (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 2c
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples at 1:1000 (fig 2c). Nat Commun (2019) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:1000; loading ...; fig 2c
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in western blot on mouse samples at 1:1000 (fig 2c). Nat Commun (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 5f
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:1000 (fig 5f). Nat Commun (2019) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:1000; loading ...; fig 5f
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples at 1:1000 (fig 5f). Nat Commun (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 6d
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 6d). Cell Discov (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 3h
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples (fig 3h). FASEB J (2019) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 3b
Cell Signaling Technology Eif2ak3 antibody (CST, 3192S) was used in western blot on human samples (fig 3b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; fig 1n
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples (fig 1n). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 2d
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 2d). J Clin Invest (2018) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:1000; fig 9e
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 16F8) was used in western blot on mouse samples at 1:1000 (fig 9e). Nat Commun (2017) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; 1:1000; loading ...; fig 6b
Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3179) was used in western blot on human samples at 1:1000 (fig 6b). Biochem Pharmacol (2017) ncbi
domestic rabbit monoclonal (16F8)
  • flow cytometry; mouse; fig 1b
In order to examine the impact of the unfolded protein response in satellite cell homeostasis during regenerative myogenesis, Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3179L) was used in flow cytometry on mouse samples (fig 1b). elife (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; 1:500; fig 6d
In order to examine the impact of the unfolded protein response in satellite cell homeostasis during regenerative myogenesis, Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3192) was used in western blot knockout validation on mouse samples at 1:500 (fig 6d). elife (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; loading ...; fig 3a
In order to determine the effect of ginsenoside Rg5 on adipose dysfunction and muscle insulin resistance, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:1000 (fig 3a). Front Pharmacol (2017) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; loading ...; fig 4e
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples (fig 4e). J Endocrinol (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:1000; loading ...; fig 3a
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192S) was used in western blot on human samples at 1:1000 (fig 3a). Nat Commun (2017) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; fig 2a
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on human samples (fig 2a). Mediators Inflamm (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2
  • western blot; mouse; 1:500; loading ...; fig 1b
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2) and in western blot on mouse samples at 1:500 (fig 1b). Mol Reprod Dev (2017) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; 1:1000; loading ...; fig 5d
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179S) was used in western blot on human samples at 1:1000 (fig 5d). PLoS ONE (2017) ncbi
domestic rabbit monoclonal (C33E10)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 7c
Cell Signaling Technology Eif2ak3 antibody (CST, 3192) was used in immunohistochemistry on mouse samples at 1:100 (fig 7c). J Am Heart Assoc (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; loading ...; fig 4c
In order to propose that casitas B-cell lymphoma family proteins protect mammary epithelial cells from proteotoxic stress-induced cell death by promoting turnover of active c-Src, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples (fig 4c). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; loading ...; fig 3b
  • western blot; rat; loading ...; fig 4a
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples (fig 3b) and in western blot on rat samples (fig 4a). J Neurosci (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179S) was used in western blot on human samples (fig 4b). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig 3a
In order to assess cyclic alterations of lipid metabolism over a 24-hour period after binge in small heterodimer partner nuclear receptor knockout mice, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 3a). Am J Pathol (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:1000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 5
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, C33E10) was used in western blot on mouse samples (fig 5). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • other; mouse; 1:500; fig 1
  • western blot; mouse; 1:500; fig 1
In order to assess the role of PERK to working memory, Cell Signaling Technology Eif2ak3 antibody (cell signaling, 3192) was used in other on mouse samples at 1:500 (fig 1) and in western blot on mouse samples at 1:500 (fig 1). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:500; fig 3
In order to assess the role of PERK to working memory, Cell Signaling Technology Eif2ak3 antibody (cell signaling, 3179) was used in western blot on mouse samples at 1:500 (fig 3). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; rat; fig 3a
In order to test if thrombospondin-4 is induced in association with ATF6alpha activation and endoplasmic reticulum expansion, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on rat samples (fig 3a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; rat; fig 3a
In order to test if thrombospondin-4 is induced in association with ATF6alpha activation and endoplasmic reticulum expansion, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in western blot on rat samples (fig 3a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; fig 2
Cell Signaling Technology Eif2ak3 antibody (CST, 3192) was used in western blot on mouse samples at 1:1000 (fig 2). Biomed Res Int (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:500; loading ...; fig 1a
  • western blot; human; 1:500; loading ...; fig 1a
In order to propose that ER stress-induced CHOP activation in the brain links palmitate-induced regulation of leptin and IGF1, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples at 1:500 (fig 1a) and in western blot on human samples at 1:500 (fig 1a). Cell Signal (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:500; loading ...; fig 1a
  • western blot; mouse; 1:500; loading ...; fig 1a
In order to propose that ER stress-induced CHOP activation in the brain links palmitate-induced regulation of leptin and IGF1, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on human samples at 1:500 (fig 1a) and in western blot on mouse samples at 1:500 (fig 1a). Cell Signal (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:500; fig 3
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, C33E10) was used in western blot on human samples at 1:500 (fig 3). elife (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:2000; fig 7
In order to study the control of homoeostasis and survival of myelinating oligodendrocytes by regulation of PERK-eIF2alpha signaling by tuberous sclerosis complex-1, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples at 1:2000 (fig 7). Nat Commun (2016) ncbi
domestic rabbit monoclonal (16F8)
  • immunohistochemistry; mouse; fig 3
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179S) was used in immunohistochemistry on mouse samples (fig 3). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 4
In order to analyze exacerbation of palmitate-induced steatosis and toxicity in hepatocytes by low density lipoprotein receptor-related protein-1 deficiency, Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3192) was used in western blot on mouse samples (fig 4). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; fig 4
In order to analyze exacerbation of palmitate-induced steatosis and toxicity in hepatocytes by low density lipoprotein receptor-related protein-1 deficiency, Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3179) was used in western blot on mouse samples (fig 4). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 1a
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on human samples (fig 1a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • immunohistochemistry; mouse; 1:1000; fig 2
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, C33E10) was used in immunohistochemistry on mouse samples at 1:1000 (fig 2). Ann Clin Transl Neurol (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 2
Cell Signaling Technology Eif2ak3 antibody (Cell signalling, C33E10) was used in western blot on human samples (fig 2). Oncogene (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; fig s3
In order to analyze induction of efficient anti-tumor immunity by vaccination with necroptotic cancer cells, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179S) was used in western blot on mouse samples (fig s3). Cell Rep (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig s3
In order to analyze induction of efficient anti-tumor immunity by vaccination with necroptotic cancer cells, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192S) was used in western blot on mouse samples (fig s3). Cell Rep (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179S) was used in western blot on mouse samples at 1:1000 (fig 2a). J Physiol Biochem (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; 1:500; fig 1d
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on human samples at 1:500 (fig 1d). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; loading ...; fig s5g
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig s5g). Cell (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; loading ...; fig s5g
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples (fig s5g). Cell (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; loading ...; fig 2b
Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3192) was used in western blot knockout validation on mouse samples (fig 2b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (16F8)
  • other; mouse; 1:130; fig 4
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 16F8) was used in other on mouse samples at 1:130 (fig 4). J Immunol (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 5
In order to study the miR-424(322)-503 cluster in the unfolded protein response, Cell Signaling Technology Eif2ak3 antibody (Cell signaling, C33E10) was used in western blot on human samples (fig 5). Sci Rep (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; fig 1
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples (fig 1). elife (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 1
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples (fig 1). elife (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:2000; fig 1
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:2000 (fig 1). Nat Cell Biol (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; fig 1F
In order to study the role of eIF2alpha in skeletal muscle stem cells, Cell Signaling Technology Eif2ak3 antibody (CST, 3179) was used in western blot on mouse samples (fig 1F). Cell Stem Cell (2016) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; fig 4
In order to examine the effect of palmitic acid exposure on HUVEC-CS cells, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on human samples (fig 4). Cell Signal (2016) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology Eif2ak3 antibody (Cell signaling, 3192) was used in western blot on human samples at 1:1000 (fig 3). Oncotarget (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • immunocytochemistry; human; 1:500; tbl 4
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in immunocytochemistry on human samples at 1:500 (tbl 4). Sci Rep (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; rat; fig 4
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on rat samples (fig 4). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 6
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on human samples (fig 6). Autophagy (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; fig 6
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on human samples (fig 6). Autophagy (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on human samples . PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; fig 4,8
  • western blot; human; fig 4,8
Cell Signaling Technology Eif2ak3 antibody (cell signaling, 3192) was used in western blot on mouse samples (fig 4,8) and in western blot on human samples (fig 4,8). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; fig 4,8
  • western blot; human; fig 4,8
Cell Signaling Technology Eif2ak3 antibody (cell signaling, 3179) was used in western blot on mouse samples (fig 4,8) and in western blot on human samples (fig 4,8). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • immunoprecipitation; human; fig 4
In order to elucidate the mechanism by which Ire1alpha cleaves mRNAs at the ER membrane, Cell Signaling Technology Eif2ak3 antibody (Cell Signalling, 3192) was used in immunoprecipitation on human samples (fig 4). elife (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; fig 2
In order to demonstrate that androgen receptor signaling modulates the unfolded protein response in prostate cancer cells, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179S) was used in western blot on human samples (fig 2). EMBO Mol Med (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; fig 2
In order to demonstrate that androgen receptor signaling modulates the unfolded protein response in prostate cancer cells, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192S) was used in western blot on human samples (fig 2). EMBO Mol Med (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; loading ...; fig 3d
  • western blot; rat; loading ...; fig 7b
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in western blot on mouse samples (fig 3d) and in western blot on rat samples (fig 7b). Free Radic Biol Med (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; rat; 1:500; fig 1
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on rat samples at 1:500 (fig 1). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000; fig 6a
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples at 1:1000 (fig 6a). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:1000; fig 6a
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in western blot on mouse samples at 1:1000 (fig 6a). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse
  • western blot; rat
In order to study autophagy in the cardiac tissue of mice with a focus on obesity, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples and in western blot on rat samples . J Lipid Res (2015) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; fig 5
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 16F8) was used in western blot on human samples (fig 5). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human
Cell Signaling Technology Eif2ak3 antibody (CST, 3192) was used in western blot on human samples . Biochem Biophys Res Commun (2015) ncbi
domestic rabbit monoclonal (16F8)
  • immunocytochemistry; rat
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in immunocytochemistry on rat samples . J Neurol Sci (2014) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human; 1:1000
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on human samples at 1:1000. FEBS Lett (2014) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; fig 4
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on human samples (fig 4). Int J Biochem Cell Biol (2014) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse
In order to study PERK signaling using an analog-sensitive PERK allele that accepts N(6)-alkylated ATP analogs, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples . Cancer Biol Ther (2014) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse
In order to examine the relationship between endoplasmic reticulum stress and autophagy in human and mouse hepatocytes during non-alcoholic fatty liver disease, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in western blot on mouse samples . Cell Death Dis (2014) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; human; 1:1000
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in western blot on human samples at 1:1000. Head Neck (2015) ncbi
domestic rabbit monoclonal (16F8)
  • immunohistochemistry; mouse
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in immunohistochemistry on mouse samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; human
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on human samples . Int J Oncol (2014) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; swine
Cell Signaling Technology Eif2ak3 antibody (CST, 3179S) was used in western blot on swine samples . PLoS ONE (2013) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot knockout validation; mouse; fig 5
In order to test if suppressing eIF2alpha kinases alleviates synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot knockout validation on mouse samples (fig 5). Nat Neurosci (2013) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse
In order to study the pathogenesis of cardiomyopathy in Friedreich ataxia, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in western blot on mouse samples . Am J Pathol (2013) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse
In order to study the pathogenesis of cardiomyopathy in Friedreich ataxia, Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3192) was used in western blot on mouse samples . Am J Pathol (2013) ncbi
domestic rabbit monoclonal (C33E10)
  • western blot; mouse; 1:1000
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3192) was used in western blot on mouse samples at 1:1000. Transl Psychiatry (2013) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; rat
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling Technology, 3179) was used in western blot on rat samples . Apoptosis (2013) ncbi
domestic rabbit monoclonal (16F8)
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology Eif2ak3 antibody (Cell Signaling, 3179) was used in western blot on mouse samples at 1:1000 (fig 6). J Biol Chem (2012) ncbi
Articles Reviewed
  1. Zhu P, Khatiwada S, Cui Y, Reineke L, Dooling S, Kim J, et al. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science. 2019;366:843-849 pubmed publisher
  2. Wang Y, Chiang I, Ohara T, Fujii S, Cheng J, Muegge B, et al. Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells. Cell. 2019;179:1144-1159.e15 pubmed publisher
  3. Hernández Alvarez M, Sebastian D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, et al. Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease. Cell. 2019;177:881-895.e17 pubmed publisher
  4. Mogilenko D, Haas J, L homme L, Fleury S, Quemener S, Levavasseur M, et al. Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019;177:1201-1216.e19 pubmed publisher
  5. Schiattarella G, Altamirano F, Tong D, French K, Villalobos E, Kim S, et al. Nitrosative stress drives heart failure with preserved ejection fraction. Nature. 2019;568:351-356 pubmed publisher
  6. Cao Y, Trillo Tinoco J, Sierra R, Anadon C, Dai W, Mohamed E, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun. 2019;10:1280 pubmed publisher
  7. Zhu H, Bhatt B, Sivaprakasam S, Cai Y, Liu S, Kodeboyina S, et al. Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR. Nat Commun. 2019;10:1084 pubmed publisher
  8. Cai Y, Zhu G, Liu S, Pan Z, Quintero M, Poole C, et al. Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation. Cell Discov. 2019;5:7 pubmed publisher
  9. Wheeler M, Jaronen M, Covacu R, Zandee S, Scalisi G, Rothhammer V, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. 2019;176:581-596.e18 pubmed publisher
  10. Westergard T, McAvoy K, Russell K, Wen X, Pang Y, Morris B, et al. Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress. EMBO Mol Med. 2019;11: pubmed publisher
  11. Gallot Y, Bohnert K, Straughn A, Xiong G, Hindi S, Kumar A. PERK regulates skeletal muscle mass and contractile function in adult mice. FASEB J. 2019;33:1946-1962 pubmed publisher
  12. Green K, Glineburg M, Kearse M, Flores B, Linsalata A, Fedak S, et al. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun. 2017;8:2005 pubmed publisher
  13. Ersoy B, Maner Smith K, Li Y, Alpertunga I, Cohen D. Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress. J Clin Invest. 2018;128:141-156 pubmed publisher
  14. Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed publisher
  15. Sun H, Jiang M, Fu X, Cai Q, Zhang J, Yin Y, et al. Mesencephalic astrocyte-derived neurotrophic factor reduces cell apoptosis via upregulating HSP70 in SHSY-5Y cells. Transl Neurodegener. 2017;6:12 pubmed publisher
  16. Yue X, Zuo Y, Ke H, Luo J, Lou L, Qin W, et al. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. Biochem Pharmacol. 2017;137:29-50 pubmed publisher
  17. Xiong G, Hindi S, Mann A, Gallot Y, Bohnert K, Cavener D, et al. The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. elife. 2017;6: pubmed publisher
  18. Xiao N, Yang L, Yang Y, Liu L, Li J, Liu B, et al. Ginsenoside Rg5 Inhibits Succinate-Associated Lipolysis in Adipose Tissue and Prevents Muscle Insulin Resistance. Front Pharmacol. 2017;8:43 pubmed publisher
  19. Kang S, Yi H, Choi M, Ryu M, Jung S, Chung H, et al. ANGPTL6 expression is coupled with mitochondrial OXPHOS function to regulate adipose FGF21. J Endocrinol. 2017;233:105-118 pubmed publisher
  20. Liu J, Wang Y, Song L, Zeng L, Yi W, Liu T, et al. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability. Nat Commun. 2017;8:14186 pubmed publisher
  21. Geraghty P, Baumlin N, SALATHE M, Foronjy R, D Armiento J. Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure. Mediators Inflamm. 2016;2016:9461289 pubmed publisher
  22. Yoon J, Park K, Hwang D, Rhee K. Importance of eIF2α phosphorylation as a protective mechanism against heat stress in mouse male germ cells. Mol Reprod Dev. 2017;84:265-274 pubmed publisher
  23. Laporte A, Barrott J, Yao R, Poulin N, Brodin B, Jones K, et al. HDAC and Proteasome Inhibitors Synergize to Activate Pro-Apoptotic Factors in Synovial Sarcoma. PLoS ONE. 2017;12:e0169407 pubmed publisher
  24. Chao M, Guo J, Cheng W, Zhu X, She Z, Huang Z, et al. Loss of Caspase-Activated DNase Protects Against Atherosclerosis in Apolipoprotein E-Deficient Mice. J Am Heart Assoc. 2016;5: pubmed publisher
  25. Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed publisher
  26. Beauvais G, Bode N, Watson J, Wen H, Glenn K, Kawano H, et al. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis. J Neurosci. 2016;36:10245-10256 pubmed
  27. Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher
  28. Yang Z, Tsuchiya H, Zhang Y, Lee S, Liu C, Huang Y, et al. REV-ERB? Activates C/EBP Homologous Protein to Control Small Heterodimer Partner-Mediated Oscillation of Alcoholic Fatty Liver. Am J Pathol. 2016;186:2909-2920 pubmed publisher
  29. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  30. Taniuchi S, Miyake M, Tsugawa K, Oyadomari M, Oyadomari S. Integrated stress response of vertebrates is regulated by four eIF2? kinases. Sci Rep. 2016;6:32886 pubmed publisher
  31. Zhu S, Henninger K, McGrath B, Cavener D. PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility. PLoS ONE. 2016;11:e0162766 pubmed publisher
  32. Krawczyk K, Ekman M, Rippe C, Grossi M, Nilsson B, Albinsson S, et al. Assessing the contribution of thrombospondin-4 induction and ATF6? activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction. Sci Rep. 2016;6:32449 pubmed publisher
  33. Liu J, Ma Y, Sun C, Li S, Wang J. High Mobility Group Box1 Protein Is Involved in Endoplasmic Reticulum Stress Induced by Clostridium difficile Toxin A. Biomed Res Int. 2016;2016:4130834 pubmed publisher
  34. Marwarha G, Claycombe K, Schommer J, Collins D, Ghribi O. Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBP? Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain. Cell Signal. 2016;28:1789-805 pubmed publisher
  35. Gallagher C, Garri C, Cain E, Ang K, Wilson C, Chen S, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. elife. 2016;5: pubmed publisher
  36. Jiang M, Liu L, He X, Wang H, Lin W, Wang H, et al. Regulation of PERK-eIF2? signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes. Nat Commun. 2016;7:12185 pubmed publisher
  37. Berthoud V, Minogue P, Lambert P, Snabb J, Beyer E. The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses. J Biol Chem. 2016;291:17569-78 pubmed publisher
  38. Hamlin A, Basford J, Jaeschke A, Hui D. LRP1 Protein Deficiency Exacerbates Palmitate-induced Steatosis and Toxicity in Hepatocytes. J Biol Chem. 2016;291:16610-9 pubmed publisher
  39. Chaveroux C, Sarcinelli C, Barbet V, Belfeki S, Barthelaix A, Ferraro Peyret C, et al. Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway. Sci Rep. 2016;6:27278 pubmed publisher
  40. Genç B, Jara J, Schultz M, Manuel M, Stanford M, Gautam M, et al. Absence of UCHL 1 function leads to selective motor neuropathy. Ann Clin Transl Neurol. 2016;3:331-45 pubmed publisher
  41. Gupta A, Hossain M, Miller N, Kerin M, Callagy G, Gupta S. NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer. Oncogene. 2016;35:5860-5871 pubmed publisher
  42. Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed publisher
  43. Soeda J, Mouralidarane A, Cordero P, Li J, Nguyen V, Carter R, et al. Maternal obesity alters endoplasmic reticulum homeostasis in offspring pancreas. J Physiol Biochem. 2016;72:281-91 pubmed publisher
  44. Martínez Pizarro A, Desviat L, Ugarte M, Perez B, Richard E. Endoplasmic Reticulum Stress and Autophagy in Homocystinuria Patients with Remethylation Defects. PLoS ONE. 2016;11:e0150357 pubmed publisher
  45. Llambi F, Wang Y, Victor B, Yang M, Schneider D, Gingras S, et al. BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation. Cell. 2016;165:421-33 pubmed publisher
  46. Saveljeva S, Cleary P, Mnich K, Ayo A, Pakos Zebrucka K, Patterson J, et al. Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival. Oncotarget. 2016;7:12254-66 pubmed publisher
  47. Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, et al. HCV induces transforming growth factor β1 through activation of endoplasmic reticulum stress and the unfolded protein response. Sci Rep. 2016;6:22487 pubmed publisher
  48. Levit Zerdoun E, Becker M, Pohlmeyer R, Wilhelm I, Maity P, Rajewsky K, et al. Survival of Igα-Deficient Mature B Cells Requires BAFF-R Function. J Immunol. 2016;196:2348-60 pubmed publisher
  49. Gupta A, Hossain M, Read D, Hetz C, Samali A, Gupta S. PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response. Sci Rep. 2015;5:18304 pubmed publisher
  50. Gao X, Krokowski D, Guan B, Bederman I, Majumder M, Parisien M, et al. Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response. elife. 2015;4:e10067 pubmed publisher
  51. Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, et al. IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation. Nat Cell Biol. 2015;17:1546-55 pubmed publisher
  52. Zismanov V, Chichkov V, Colangelo V, Jamet S, Wang S, Syme A, et al. Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal. Cell Stem Cell. 2016;18:79-90 pubmed publisher
  53. Gustavo Vazquez Jimenez J, Chavez Reyes J, Romero Garcia T, Zarain Herzberg A, Valdes Flores J, Manuel Galindo Rosales J, et al. Palmitic acid but not palmitoleic acid induces insulin resistance in a human endothelial cell line by decreasing SERCA pump expression. Cell Signal. 2016;28:53-9 pubmed publisher
  54. Patel M, Jacobson B, Ji Y, Drees J, Tang S, Xiong K, et al. Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer. Oncotarget. 2015;6:33165-77 pubmed publisher
  55. Nath A, Li I, Roberts L, Chan C. Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma. Sci Rep. 2015;5:14752 pubmed publisher
  56. Bejaoui M, Pantazi E, De Luca V, Panisello A, Folch Puy E, Hotter G, et al. Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage. PLoS ONE. 2015;10:e0134499 pubmed publisher
  57. Treacy Abarca S, Mukherjee S. Legionella suppresses the host unfolded protein response via multiple mechanisms. Nat Commun. 2015;6:7887 pubmed publisher
  58. Artero Castro A, Perez Alea M, Feliciano A, Leal J, Genestar M, Castellvi J, et al. Disruption of the ribosomal P complex leads to stress-induced autophagy. Autophagy. 2015;11:1499-519 pubmed publisher
  59. D Osualdo A, Anania V, Yu K, Lill J, Kaufman R, Matsuzawa S, et al. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. PLoS ONE. 2015;10:e0130635 pubmed publisher
  60. So J, Cho S, Min S, Kimball S, Lee A. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis. Mol Cell Biol. 2015;35:2761-70 pubmed publisher
  61. Plumb R, Zhang Z, Appathurai S, Mariappan M. A functional link between the co-translational protein translocation pathway and the UPR. elife. 2015;4: pubmed publisher
  62. Sheng X, Arnoldussen Y, Storm M, Tesikova M, Nenseth H, Zhao S, et al. Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Mol Med. 2015;7:788-801 pubmed publisher
  63. Pilar Valdecantos M, Prieto Hontoria P, Pardo V, Módol T, Santamaría B, Weber M, et al. Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes. Free Radic Biol Med. 2015;84:263-278 pubmed publisher
  64. Wong M, Nicholson C, Holloway A, Hardy D. Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta. PLoS ONE. 2015;10:e0122295 pubmed publisher
  65. Dametto P, Lakkaraju A, Bridel C, Villiger L, O CONNOR T, Herrmann U, et al. Neurodegeneration and unfolded-protein response in mice expressing a membrane-tethered flexible tail of PrP. PLoS ONE. 2015;10:e0117412 pubmed publisher
  66. Jaishy B, Zhang Q, Chung H, Riehle C, Soto J, Jenkins S, et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J Lipid Res. 2015;56:546-61 pubmed publisher
  67. Davis A, Qiao S, Lesson J, Rojo de la Vega M, Park S, Seanez C, et al. The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells. J Biol Chem. 2015;290:1623-38 pubmed publisher
  68. Deegan S, Koryga I, Glynn S, Gupta S, Gorman A, Samali A. A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy. Biochem Biophys Res Commun. 2015;456:305-11 pubmed publisher
  69. Duś Szachniewicz K, Wozniak M, Nelke K, Gamian E, Gerber H, Ziółkowski P. Protein tyrosine phosphatase receptor R and Z1 expression as independent prognostic indicators in oral squamous cell carcinoma. Head Neck. 2015;37:1816-22 pubmed publisher
  70. Yang W, Shen Y, Chen Y, Chen L, Wang L, Wang H, et al. Mesencephalic astrocyte-derived neurotrophic factor prevents neuron loss via inhibiting ischemia-induced apoptosis. J Neurol Sci. 2014;344:129-38 pubmed publisher
  71. Le Pape S, Dimitrova E, Hannaert P, Konovalov A, Volmer R, Ron D, et al. Polynomial algebra reveals diverging roles of the unfolded protein response in endothelial cells during ischemia-reperfusion injury. FEBS Lett. 2014;588:3062-7 pubmed publisher
  72. Lim Y, Lee D, Kalichamy K, Hong S, Michalak M, Ahnn J, et al. Sumoylation regulates ER stress response by modulating calreticulin gene expression in XBP-1-dependent mode in Caenorhabditis elegans. Int J Biochem Cell Biol. 2014;53:399-408 pubmed publisher
  73. Maas N, Singh N, Diehl J. Generation and characterization of an analog-sensitive PERK allele. Cancer Biol Ther. 2014;15:1106-11 pubmed publisher
  74. Gonzalez Rodriguez A, Mayoral R, Agra N, Valdecantos M, Pardo V, Miquilena Colina M, et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. Cell Death Dis. 2014;5:e1179 pubmed publisher
  75. Nagelkerke A, Sweep F, Stegeman H, Grenman R, Kaanders J, Bussink J, et al. Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma. Head Neck. 2015;37:896-905 pubmed publisher
  76. Wang B, Dai S, Dong Z, Sun Y, Song X, Guo C, et al. The modulation of endoplasmic reticulum stress by chemical chaperone upregulates immune negative cytokine IL-35 in apolipoprotein E-deficient mice. PLoS ONE. 2014;9:e87787 pubmed publisher
  77. Sisinni L, Maddalena F, Lettini G, Condelli V, Matassa D, Esposito F, et al. TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells. Int J Oncol. 2014;44:573-82 pubmed publisher
  78. Yang Z, Xu Y, Xu L, Maccauro G, Rossi B, Chen Y, et al. Regulation of autophagy via PERK-eIF2? effectively relieve the radiation myelitis induced by iodine-125. PLoS ONE. 2013;8:e76819 pubmed publisher
  79. Ma T, Trinh M, Wexler A, Bourbon C, Gatti E, Pierre P, et al. Suppression of eIF2? kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci. 2013;16:1299-305 pubmed publisher
  80. Huang M, Sivagurunathan S, Ting S, Jansson P, Austin C, Kelly M, et al. Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2? phosphorylation, and the induction of downstream targets. Am J Pathol. 2013;183:745-57 pubmed publisher
  81. Devi L, Ohno M. Mechanisms that lessen benefits of ?-secretase reduction in a mouse model of Alzheimer's disease. Transl Psychiatry. 2013;3:e284 pubmed publisher
  82. Zhuo X, Wu Y, Ni Y, Liu J, Gong M, Wang X, et al. Isoproterenol instigates cardiomyocyte apoptosis and heart failure via AMPK inactivation-mediated endoplasmic reticulum stress. Apoptosis. 2013;18:800-10 pubmed publisher
  83. Henke N, Albrecht P, Pfeiffer A, Toutzaris D, Zanger K, Methner A. Stromal interaction molecule 1 (STIM1) is involved in the regulation of mitochondrial shape and bioenergetics and plays a role in oxidative stress. J Biol Chem. 2012;287:42042-52 pubmed publisher