This is a Validated Antibody Database (VAD) review about rat Dyrk, based on 5 published articles (read how Labome selects the articles), using Dyrk antibody in all methods. It is aimed to help Labome visitors find the most suited Dyrk antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Dyrk synonym: Dyrk; PSK47; dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual Specificity Yak1-related kinase; MNBH; RP86; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; protein kinase minibrain homolog

R&D Systems
sheep polyclonal
  • western blot; human
R&D Systems Dyrk antibody (R&D Systems, AF5407) was used in western blot on human samples . J Biol Chem (2015) ncbi
MilliporeSigma
rabbit polyclonal
  • western blot; human; fig 3c
In order to identify analogs of harmine as a new class of human beta cell mitogenic compounds and identify the pathways they activate, MilliporeSigma Dyrk antibody (Sigma, D-1694) was used in western blot on human samples (fig 3c). Nat Med (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D30C10)
  • western blot; human; loading ...; fig 4 - s1d
Cell Signaling Technology Dyrk antibody (Cell Signalling Technologies, 8765) was used in western blot on human samples (fig 4 - s1d). elife (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:3000; fig 2
In order to study kinase DYRK1A selective inhibition by targeting its folding process, Cell Signaling Technology Dyrk antibody (Cell Signaling Technology, 2771S) was used in western blot on human samples at 1:3000 (fig 2). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunoprecipitation; human; fig 2
  • western blot; human; 1:1000; fig 3
In order to report the contribution of DYRK1A and DYRK1B in cancer stem cells, Cell Signaling Technology Dyrk antibody (Cell Signaling Technology, 2771) was used in immunoprecipitation on human samples (fig 2) and in western blot on human samples at 1:1000 (fig 3). Nature (2016) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Dyrk antibody (Cell Signaling Technology, 2771) was used in western blot on human samples . J Biol Chem (2015) ncbi
Articles Reviewed
  1. Bellmaine S, Ovchinnikov D, Manallack D, Cuddy C, Elefanty A, Stanley E, et al. Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells. elife. 2017;6: pubmed publisher
  2. Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, et al. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016;7:11391 pubmed publisher
  3. Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
  4. Jin N, Yin X, Gu J, Zhang X, Shi J, Qian W, et al. Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE. J Biol Chem. 2015;290:15219-37 pubmed publisher
  5. Wang P, Alvarez Perez J, Felsenfeld D, Liu H, Sivendran S, Bender A, et al. A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication. Nat Med. 2015;21:383-8 pubmed publisher