This is a Validated Antibody Database (VAD) review about rat Dusp4, based on 2 published articles (read how Labome selects the articles), using Dusp4 antibody in all methods. It is aimed to help Labome visitors find the most suited Dusp4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Dusp4 synonym: Mkp-2; Mkp2; dual specificity protein phosphatase 4; MAP kinase phosphatase 2; mitogen-activated protein kinase phosphatase 2

Santa Cruz Biotechnology
mouse monoclonal (F-10)
  • ChIP-Seq; human; fig 1
  • chromatin immunoprecipitation; human; fig 3
  • immunocytochemistry; human; fig 2
  • western blot; human; fig s5
In order to analyze the DUSP family members and their differential roles in epithelial to mesenchymal transition and cancer stem cell regulation in breast cancer, Santa Cruz Biotechnology Dusp4 antibody (Santa Cruz Biotechnology, sc-17821) was used in ChIP-Seq on human samples (fig 1), in chromatin immunoprecipitation on human samples (fig 3), in immunocytochemistry on human samples (fig 2) and in western blot on human samples (fig s5). PLoS ONE (2016) ncbi
BD Biosciences
mouse monoclonal (48/MKP2)
  • western blot; mouse; fig 5
In order to analyze regulation of NLRP3 inflammasome in adipose tissue by phosphodiesterase 3B (PDE3B), BD Biosciences Dusp4 antibody (BD Biosciences, 610850) was used in western blot on mouse samples (fig 5). Sci Rep (2016) ncbi
Articles Reviewed
  1. Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed publisher
  2. Boulding T, Wu F, McCuaig R, Dunn J, Sutton C, Hardy K, et al. Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer. PLoS ONE. 2016;11:e0148065 pubmed publisher