This is a Validated Antibody Database (VAD) review about rat Ddb1, based on 11 published articles (read how Labome selects the articles), using Ddb1 antibody in all methods. It is aimed to help Labome visitors find the most suited Ddb1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ddb1 synonym: DNA damage-binding protein 1; damage-specific DNA binding protein 1, 127kDa

Abcam
rabbit monoclonal (EPR6089)
  • immunoprecipitation; human; loading ...; fig 4a
Abcam Ddb1 antibody (AbCam, ab109027) was used in immunoprecipitation on human samples (fig 4a). elife (2019) ncbi
rabbit monoclonal (EPR6089)
  • western blot; human; 1:10,000; loading ...; fig 3e
Abcam Ddb1 antibody (Abcam, ab109027) was used in western blot on human samples at 1:10,000 (fig 3e). Science (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-1)
  • western blot; mouse; loading ...; fig 3d
In order to use knockout mice to determine the role of cereblon in T cells, Santa Cruz Biotechnology Ddb1 antibody (Santa Cruz, B-1) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (8)
  • western blot; human; 1:500; fig 4
Santa Cruz Biotechnology Ddb1 antibody (Santa Cruz, sc-136180) was used in western blot on human samples at 1:500 (fig 4). FASEB J (2016) ncbi
Invitrogen
mouse monoclonal (ZD001)
  • western blot; human; 1:1000; fig 3
In order to study UVA response and nucleotide excision repair deficiency in melanoma, Invitrogen Ddb1 antibody (Invitrogen, ZD001) was used in western blot on human samples at 1:1000 (fig 3). Exp Hematol Oncol (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D4C8)
  • western blot; human; 1:1000; loading ...; fig s8b
Cell Signaling Technology Ddb1 antibody (Cell Signaling, 6998) was used in western blot on human samples at 1:1000 (fig s8b). Nat Commun (2018) ncbi
rabbit monoclonal (D4C8)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology Ddb1 antibody (CST, 6998) was used in western blot on human samples (fig 2c). Genes Dev (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4e
Cell Signaling Technology Ddb1 antibody (Cell Signaling, S428) was used in western blot on human samples at 1:1000 (fig 4e). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Ddb1 antibody (Cell Signaling Technology, 5428) was used in western blot on human samples at 1:1000 (fig 2). Nature (2016) ncbi
rabbit monoclonal (D4C8)
  • western blot; human; fig 5c
Cell Signaling Technology Ddb1 antibody (Cell Signaling, 6998) was used in western blot on human samples (fig 5c). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; human
In order to study how phosphorylation alters COP1-binding sites of oncoproteins, Cell Signaling Technology Ddb1 antibody (Cell Signaling, 5428S) was used in western blot on human samples . Cancer Cell (2014) ncbi
Articles Reviewed
  1. Silva M, Ferguson F, Cai Q, Donovan K, Nandi G, Patnaik D, et al. Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. elife. 2019;8: pubmed publisher
  2. Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, et al. The protective role of DOT1L in UV-induced melanomagenesis. Nat Commun. 2018;9:259 pubmed publisher
  3. Morgan M, Rickels R, Collings C, He X, Cao K, Herz H, et al. A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation. Genes Dev. 2017;31:2003-2014 pubmed publisher
  4. Han T, Goralski M, Gaskill N, Capota E, Kim J, Ting T, et al. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. Science. 2017;356: pubmed publisher
  5. Prince E, Balakrishnan I, Shah M, Mulcahy Levy J, Griesinger A, Alimova I, et al. Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma. Oncotarget. 2016;7:53881-53894 pubmed publisher
  6. Kang J, Park S, Jeong S, Han M, Lee C, Lee K, et al. Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T-cell activation. Proc Natl Acad Sci U S A. 2016;113:8771-6 pubmed publisher
  7. Decorsière A, Mueller H, van Breugel P, Abdul F, Gerossier L, Beran R, et al. Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. Nature. 2016;531:386-9 pubmed publisher
  8. Murray H, Maltby V, Smith D, Bowden N. Nucleotide excision repair deficiency in melanoma in response to UVA. Exp Hematol Oncol. 2015;5:6 pubmed publisher
  9. Lyu L, Whitcomb E, Jiang S, Chang M, Gu Y, Duncan M, et al. Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract. FASEB J. 2016;30:1087-95 pubmed publisher
  10. Sjögren B, Swaney S, Neubig R. FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex. PLoS ONE. 2015;10:e0123581 pubmed publisher
  11. Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher