This is a Validated Antibody Database (VAD) review about rat Cul5, based on 6 published articles (read how Labome selects the articles), using Cul5 antibody in all methods. It is aimed to help Labome visitors find the most suited Cul5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
domestic rabbit monoclonal (EPR14725)
  • western blot knockout validation; human; 1:1000; loading ...; fig 2d
Abcam Cul5 antibody (Abcam, ab184177) was used in western blot knockout validation on human samples at 1:1000 (fig 2d). elife (2019) ncbi
Abcam
domestic rabbit monoclonal (EPR14725)
  • western blot knockout validation; human; loading ...; fig 4e
Abcam Cul5 antibody (Abcam, ab184177) was used in western blot knockout validation on human samples (fig 4e). elife (2019) ncbi
Abcam
domestic rabbit monoclonal (EPR14725)
  • western blot; human; loading ...; fig s1d
Abcam Cul5 antibody (Abcam, 184177) was used in western blot on human samples (fig s1d). Cell Death Differ (2022) ncbi
domestic rabbit monoclonal (EPR14725)
  • western blot knockout validation; human; 1:1000; loading ...; fig 2d
Abcam Cul5 antibody (Abcam, ab184177) was used in western blot knockout validation on human samples at 1:1000 (fig 2d). elife (2019) ncbi
domestic rabbit monoclonal (EPR14725)
  • western blot knockout validation; human; loading ...; fig 4e
Abcam Cul5 antibody (Abcam, ab184177) was used in western blot knockout validation on human samples (fig 4e). elife (2019) ncbi
domestic rabbit monoclonal (EPR14725)
  • western blot; human; loading ...; fig 5b
Abcam Cul5 antibody (Abcam, ab184177) was used in western blot on human samples (fig 5b). Nat Chem Biol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-6)
  • western blot; human; 1:1000; loading ...; fig s4b
Santa Cruz Biotechnology Cul5 antibody (Santa Cruz, sc-373822) was used in western blot on human samples at 1:1000 (fig s4b). Nat Commun (2018) ncbi
mouse monoclonal (F-6)
  • western blot; human; 1 ug/ml; loading ...; fig 1E
Santa Cruz Biotechnology Cul5 antibody (Santa cruz, sc-373822) was used in western blot on human samples at 1 ug/ml (fig 1E). J Cell Biol (2016) ncbi
Articles Reviewed
  1. Fan Y, Hou T, Dan W, Zhu Y, Liu B, Wei Y, et al. ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression. Cell Death Differ. 2022;: pubmed publisher
  2. Zeng H, Castillo Cabrera J, Manser M, Lu B, Yang Z, Strande V, et al. Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC. elife. 2019;8: pubmed publisher
  3. Kabir S, Cidado J, Andersen C, Dick C, Lin P, Mitros T, et al. The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells. elife. 2019;8: pubmed publisher
  4. Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, et al. Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II. Nat Commun. 2018;9:4394 pubmed publisher
  5. Scott D, Hammill J, Min J, Rhee D, Connelly M, Sviderskiy V, et al. Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat Chem Biol. 2017;13:850-857 pubmed publisher
  6. Uematsu K, Okumura F, Tonogai S, Joo Okumura A, Alemayehu D, Nishikimi A, et al. ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation. J Cell Biol. 2016;215:95-106 pubmed