This is a Validated Antibody Database (VAD) review about rat Cttn, based on 8 published articles (read how Labome selects the articles), using Cttn antibody in all methods. It is aimed to help Labome visitors find the most suited Cttn antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cttn synonym: Cttnb; src substrate cortactin

Abcam
mouse monoclonal (4F11)
  • immunocytochemistry; rat; 1:600; loading ...; fig 1a
  • immunocytochemistry; human; 1:600; loading ...; fig 1a
Abcam Cttn antibody (Abcam, ab33333) was used in immunocytochemistry on rat samples at 1:600 (fig 1a) and in immunocytochemistry on human samples at 1:600 (fig 1a). J Cell Biol (2017) ncbi
mouse monoclonal (4F11)
  • immunocytochemistry; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 3e
Abcam Cttn antibody (Abcam, ab33333) was used in immunocytochemistry on human samples (fig 6a) and in western blot on human samples (fig 3e). Mol Biol Cell (2017) ncbi
rabbit monoclonal (EP1922Y)
  • western blot; mouse; loading ...; fig 9c
Abcam Cttn antibody (abcam, ab81208) was used in western blot on mouse samples (fig 9c). EMBO Rep (2016) ncbi
rabbit monoclonal (EP1922Y)
  • immunocytochemistry; human; loading ...; fig 4e
Abcam Cttn antibody (Abcam, ab81208) was used in immunocytochemistry on human samples (fig 4e). elife (2014) ncbi
rabbit monoclonal (EP1922Y)
  • immunohistochemistry - paraffin section; human
Abcam Cttn antibody (Abcam, ab81208) was used in immunohistochemistry - paraffin section on human samples . Int J Cancer (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-4)
  • western blot; human
Santa Cruz Biotechnology Cttn antibody (Santa Cruz, sc-55578) was used in western blot on human samples . Cell Microbiol (2015) ncbi
MilliporeSigma
rabbit polyclonal
  • western blot; mouse; loading ...; fig 9c
MilliporeSigma Cttn antibody (Sigma, SAB4504373) was used in western blot on mouse samples (fig 9c). EMBO Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 9c
MilliporeSigma Cttn antibody (Sigma, SAB4504372) was used in western blot on mouse samples (fig 9c). EMBO Rep (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human
MilliporeSigma Cttn antibody (Sigma-Aldrich, C 7112) was used in immunocytochemistry on human samples and in western blot on human samples . Cell Microbiol (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4b
Cell Signaling Technology Cttn antibody (Cell Signaling, 3502) was used in western blot on mouse samples at 1:1000 (fig 4b). Aging Cell (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 4
  • immunocytochemistry; human; 1:100; fig 4
In order to study phosphorylation events at sites of adhesion, Cell Signaling Technology Cttn antibody (Cell Signaling Technology, 4569S) was used in western blot on mouse samples at 1:1000 (fig 4) and in immunocytochemistry on human samples at 1:100 (fig 4). Nat Commun (2015) ncbi
Articles Reviewed
  1. Baglietto Vargas D, Prieto G, Limon A, Forner S, Rodriguez Ortiz C, Ikemura K, et al. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell. 2018;17:e12791 pubmed publisher
  2. Donnelly S, Cabrera R, Mao S, Christin J, Wu B, Guo W, et al. Rac3 regulates breast cancer invasion and metastasis by controlling adhesion and matrix degradation. J Cell Biol. 2017;216:4331-4349 pubmed publisher
  3. Rosenberg B, Gil Henn H, Mader C, Halo T, Yin T, Condeelis J, et al. Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells. Mol Biol Cell. 2017;28:1347-1360 pubmed publisher
  4. Sánchez A, Urrego D, Pardo L. Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium. EMBO Rep. 2016;17:708-23 pubmed publisher
  5. Bonfim Melo A, Zanetti B, Ferreira Ã, Vandoninck S, Han S, Van Lint J, et al. Trypanosoma cruzi extracellular amastigotes trigger the protein kinase D1-cortactin-actin pathway during cell invasion. Cell Microbiol. 2015;17:1797-810 pubmed publisher
  6. Robertson J, Jacquemet G, Byron A, Jones M, Warwood S, Selley J, et al. Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling. Nat Commun. 2015;6:6265 pubmed publisher
  7. Kaur S, Fielding A, Gassner G, Carter N, Royle S. An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis. elife. 2014;3:e00829 pubmed publisher
  8. Lin Y, Izbicki J, König A, Habermann J, Blechner C, Lange T, et al. Expression of DIAPH1 is up-regulated in colorectal cancer and its down-regulation strongly reduces the metastatic capacity of colon carcinoma cells. Int J Cancer. 2014;134:1571-82 pubmed publisher