This is a Validated Antibody Database (VAD) review about rat Ctsb, based on 5 published articles (read how Labome selects the articles), using Ctsb antibody in all methods. It is aimed to help Labome visitors find the most suited Ctsb antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ctsb synonym: cathepsin B; RSG-2; cathepsin B1

Santa Cruz Biotechnology
mouse monoclonal (H-5)
  • western blot; dog; fig s4b
Santa Cruz Biotechnology Ctsb antibody (SantaCruz, sc-365558) was used in western blot on dog samples (fig s4b). J Cell Sci (2018) ncbi
Sigma-Aldrich
mouse monoclonal (CB59-4B11)
  • western blot; rabbit; 1:1000; fig 2
In order to characterize the role of endolysosomes in skeletal muscle pathology observed in a model of Alzheimer's disease with a cholesterol-fed rabbit, Sigma-Aldrich Ctsb antibody (Sigma, C6243) was used in western blot on rabbit samples at 1:1000 (fig 2). Front Aging Neurosci (2016) ncbi
mouse monoclonal (CB59-4B11)
  • western blot; human; 1:1000; fig 7
In order to investigate the effect of Obatoclax in esophageal cancer cells, Sigma-Aldrich Ctsb antibody (Sigma, C6243) was used in western blot on human samples at 1:1000 (fig 7). Oncotarget (2016) ncbi
mouse monoclonal (CB59-4B11)
  • western blot; rabbit; fig 3
Sigma-Aldrich Ctsb antibody (Sigma, C6243) was used in western blot on rabbit samples (fig 3). Arthritis Res Ther (2015) ncbi
EMD Millipore
mouse monoclonal
  • immunohistochemistry; human; loading ...; fig 5b
EMD Millipore Ctsb antibody (Millipore, IM27L) was used in immunohistochemistry on human samples (fig 5b). Autophagy (2016) ncbi
Articles Reviewed
  1. Kuchitsu Y, Homma Y, Fujita N, Fukuda M. Rab7 knockout unveils regulated autolysosome maturation induced by glutamine starvation. J Cell Sci. 2018;131: pubmed publisher
  2. Hernandez Tiedra S, Fabrias G, Davila D, Salanueva I, Casas J, Montes L, et al. Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. Autophagy. 2016;12:2213-2229 pubmed
  3. Chen X, Wagener J, Ghribi O, Geiger J. Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease. Front Aging Neurosci. 2016;8:129 pubmed publisher
  4. Yu L, Wu W, Gu C, Zhong D, Zhao X, Kong Y, et al. Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells. Oncotarget. 2016;7:14693-707 pubmed publisher
  5. Kyostio Moore S, Piraino S, Berthelette P, Moran N, Serriello J, Bendele A, et al. Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis. Arthritis Res Ther. 2015;17:5 pubmed publisher