This is a Validated Antibody Database (VAD) review about rat Cops5, based on 8 published articles (read how Labome selects the articles), using Cops5 antibody in all methods. It is aimed to help Labome visitors find the most suited Cops5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cops5 synonym: COP9 signalosome complex subunit 5; COP9 (constitutive photomorphogenic) homolog, subunit 5

Santa Cruz Biotechnology
mouse monoclonal (B-7)
  • western blot; human; loading ...; fig s6y
Santa Cruz Biotechnology Cops5 antibody (Santa Cruz Biotechnology Inc, sc-13157) was used in western blot on human samples (fig s6y). Sci Adv (2018) ncbi
mouse monoclonal
  • western blot; human; fig 6
In order to study the cullin-RING ubiquitin ligase deneddylation cycle and COP9-signalosome activation by structural and kinetic analysis, Santa Cruz Biotechnology Cops5 antibody (Santa Cruz Biotechnology, sc-393725) was used in western blot on human samples (fig 6). elife (2016) ncbi
mouse monoclonal (B-7)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Cops5 antibody (SCBT, B-7) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Cops5 antibody (SCBT, B-7) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (42)
  • western blot; human
In order to study the effect of neddylation on COP9-Signalosome deneddylase activity, Santa Cruz Biotechnology Cops5 antibody (Santa Cruz Biotechnology, sc-135954) was used in western blot on human samples . Cell Div (2015) ncbi
mouse monoclonal (B-7)
  • western blot; human
In order to examine the relation between cullin 4B variants and intellectual disability, Santa Cruz Biotechnology Cops5 antibody (Santa Cruz, sc-13157) was used in western blot on human samples . Hum Mutat (2015) ncbi
mouse monoclonal (B-7)
  • immunoprecipitation; human
  • western blot; human
In order to study the role in prostate cancer poliferation of a complex containing COP9 subunits 4 and 5 along with sGC-alpha1 and p53, Santa Cruz Biotechnology Cops5 antibody (Santa Cruz Biotechnology, sc-13157) was used in immunoprecipitation on human samples and in western blot on human samples . Mol Endocrinol (2014) ncbi
Cell Signaling Technology
rabbit polyclonal
  • immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human; 1:1000
Cell Signaling Technology Cops5 antibody (Cell Signalling Technology, 6895) was used in immunoprecipitation on human samples , in immunocytochemistry on human samples and in western blot on human samples at 1:1000. Cell Signal (2014) ncbi
BD Biosciences
mouse monoclonal (42/JAB1)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...
In order to propose a tumor-suppressive activity for macrophage migration inhibitory factor in murine skin, BD Biosciences Cops5 antibody (Becton Dickinson, 42) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. FASEB J (2017) ncbi
Articles Reviewed
  1. Liu Q, Wu Y, Qin Y, Hu J, Xie W, Qin F, et al. Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses. Sci Adv. 2018;4:eaar2824 pubmed publisher
  2. Brocks T, Fedorchenko O, Schliermann N, Stein A, Moll U, Seegobin S, et al. Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin. FASEB J. 2017;31:526-543 pubmed publisher
  3. Mosadeghi R, Reichermeier K, Winkler M, Schreiber A, Reitsma J, Zhang Y, et al. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle. elife. 2016;5: pubmed publisher
  4. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  5. Bornstein G, Grossman C. COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex. Cell Div. 2015;10:5 pubmed publisher
  6. Vulto van Silfhout A, Nakagawa T, Bahi Buisson N, Haas S, Hu H, Bienek M, et al. Variants in CUL4B are associated with cerebral malformations. Hum Mutat. 2015;36:106-17 pubmed publisher
  7. Tanaka T, Iino M. Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1. Cell Signal. 2014;26:2071-85 pubmed publisher
  8. Bhansali M, Shemshedini L. COP9 subunits 4 and 5 target soluble guanylyl cyclase ?1 and p53 in prostate cancer cells. Mol Endocrinol. 2014;28:834-45 pubmed publisher