This is a Validated Antibody Database (VAD) review about rat Chek1, based on 215 published articles (read how Labome selects the articles), using Chek1 antibody in all methods. It is aimed to help Labome visitors find the most suited Chek1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (G-4)
  • western blot knockout validation; mouse; fig 3
In order to assess the abilities of Chk1 mutants to reverse the defects of Chk1-null cells, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot knockout validation on mouse samples (fig 3). Mol Cell Biol (2007) ncbi
Santa Cruz Biotechnology
mouse monoclonal (G-4)
  • western blot; human; 1:200; loading ...; fig 13e
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples at 1:200 (fig 13e). elife (2021) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:100; loading ...; fig 1a, 1b
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples at 1:100 (fig 1a, 1b). Sci Rep (2021) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 4a
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc8408) was used in western blot on human samples (fig 4a). Sci Rep (2021) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; loading ...; fig s2c
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on mouse samples (fig s2c). Blood (2021) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; loading ...; fig s3a
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on mouse samples (fig s3a). Cancer Res (2021) ncbi
mouse monoclonal (2G11D5)
  • western blot; mouse; loading ...; fig 7a
  • western blot; human; loading ...; fig 7a
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-56288) was used in western blot on mouse samples (fig 7a) and in western blot on human samples (fig 7a). Cells (2020) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 7d
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples (fig 7d). Mol Cancer (2020) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:500; loading ...; fig s2d
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in western blot on human samples at 1:500 (fig s2d). Sci Adv (2019) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 1a
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in western blot on human samples (fig 1a). Mol Cell (2019) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:500; loading ...; fig 4e
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in western blot on human samples at 1:500 (fig 4e). Sci Rep (2018) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig s15a
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig s15a). Science (2018) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; loading ...; fig 1b
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology Inc, sc-8408) was used in western blot on mouse samples (fig 1b). Nature (2018) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 6f
Santa Cruz Biotechnology Chek1 antibody (SantaCruz, sc-8408) was used in western blot on human samples (fig 6f). Mol Cell (2018) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig s10
In order to investigate how the von Hippel-Lindau tumor suppressor gene regulates metabolism in renal cell carcinoma, Santa Cruz Biotechnology Chek1 antibody (SantaCruz, sc-8408) was used in western blot on human samples (fig s10). J Clin Invest (2017) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 2g
Santa Cruz Biotechnology Chek1 antibody (Santa cruz, Sc8408) was used in western blot on human samples (fig 2g). Genes Dev (2017) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 2c
In order to examine the effects of the arginine methyltransferase PRMT5 on homologous recombination-mediated double-strand break repair, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, SC8408) was used in western blot on human samples (fig 2c). Mol Cell (2017) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; loading ...; fig s4c
In order to analyze the effect of CX-5461 as a G-quadruplex DNA stabilizer, Santa Cruz Biotechnology Chek1 antibody (Santa CruZ, SC-8408) was used in western blot on human samples at 1:1000 (fig s4c). Nat Commun (2017) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:500; loading ...; fig 1D; 2G
  • western blot; mouse; 1:500; loading ...; fig 2A
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples at 1:500 (fig 1D; 2G) and in western blot on mouse samples at 1:500 (fig 2A). Nucleic Acids Res (2017) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 2a
  • western blot; mouse; loading ...; fig 7a
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 2a) and in western blot on mouse samples (fig 7a). Genes Dev (2017) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; loading ...; fig S1D
In order to find depletion of human Cactin leads to premature sister chromatid separation, genome instability and cell proliferation arrest, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples at 1:1000 (fig S1D). J Cell Sci (2017) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:500; loading ...; fig s6a
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples at 1:500 (fig s6a). PLoS ONE (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig s5b
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples (fig s5b). Oncotarget (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 9c
In order to propose that WRN interacts with HDACs to facilitate activity of stalled replication forks under conditions of replication stress, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 9c). J Biol Chem (2016) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; 1:200; fig s1
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on mouse samples at 1:200 (fig s1). Nat Commun (2016) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; 1:1000; loading ...; fig 5b
In order to investigate the link between NEAT1 paraspeckles, p53 biology, and tumorigenesis, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on mouse samples at 1:1000 (fig 5b). Nat Med (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:800; fig 3
Santa Cruz Biotechnology Chek1 antibody (santa Cruz, G-4) was used in western blot on human samples at 1:800 (fig 3). Int J Mol Sci (2016) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; 1:1000; fig 3
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on mouse samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:500; loading ...; fig s5a
In order to describe how a CHK1 inhibitor reduces the growth of radioresistant breast cancer cells, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, G-4) was used in western blot on human samples at 1:500 (fig s5a). Oncotarget (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 5
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples (fig 5). Cell Rep (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 2
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples (fig 2). Cell Rep (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 1a
Santa Cruz Biotechnology Chek1 antibody (santa cruz, sc- 8408) was used in western blot on human samples (fig 1a). J Biol Chem (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 6
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples (fig 6). Mol Biol Cell (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:2000; fig 6
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples at 1:2000 (fig 6). Oncotarget (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; loading ...; fig st3
In order to study the DNA damage response in senescent epithelial cells, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples at 1:1000 (fig st3). Nat Commun (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 1
In order to investigate the role of topoisomerase IIbeta-binding protein 1 in DNA repair and its contribution to cancer, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 1). J Cell Biol (2016) ncbi
mouse monoclonal (G-4)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Chek1 antibody (SCBT, G-4) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 2d
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples (fig 2d). Nucleic Acids Res (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 3
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples (fig 3). J Cell Biol (2016) ncbi
mouse monoclonal (G-4)
  • immunoprecipitation; mouse; fig 5
  • western blot; mouse; fig 5
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in immunoprecipitation on mouse samples (fig 5) and in western blot on mouse samples (fig 5). Sci Rep (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; fig 4
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples at 1:1000 (fig 4). Nat Genet (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 1
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 1). Sci Rep (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; loading ...; fig 5d
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc8408) was used in western blot on human samples at 1:1000 (fig 5d). Oncogene (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig s5
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, G-4) was used in western blot on human samples (fig s5). PLoS ONE (2015) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; fig 4a
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on mouse samples (fig 4a). PLoS ONE (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 3
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 3). PLoS Genet (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:500; fig s5
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples at 1:500 (fig s5). Nat Commun (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples . Mol Cancer Ther (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; fig 9
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, SC-8408) was used in western blot on human samples at 1:1000 (fig 9). Cancers (Basel) (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig s3e
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, SC8408) was used in western blot on human samples (fig s3e). Cell Death Differ (2016) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 1
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 1). Viruses (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 5
Santa Cruz Biotechnology Chek1 antibody (santa Cruz, sc-8408) was used in western blot on human samples (fig 5). J Biol Chem (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 1
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, SC-8408) was used in western blot on human samples . Mutat Res (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 4
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples (fig 4). J Cell Biol (2015) ncbi
mouse monoclonal (G-4)
  • reverse phase protein lysate microarray; human; 1:1000; fig 4
In order to identify a novel DNA2- and WRN-dependent mechanism of reversed replication fork processing and restart after prolonged genotoxic stress, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in reverse phase protein lysate microarray on human samples at 1:1000 (fig 4). J Cell Biol (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human
In order to examine the role of NF-kappaB during the human papillomavirus life cycle, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, G-4) was used in western blot on human samples . J Virol (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig s7
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig s7). Nucleic Acids Res (2015) ncbi
mouse monoclonal (DCS-310)
  • western blot; mouse; 1:100; fig 6
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-56291) was used in western blot on mouse samples at 1:100 (fig 6). Cell Cycle (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 4
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 4). Cell Cycle (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 1
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in western blot on human samples (fig 1). Oncoscience (2014) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; fig s7
In order to determine how PAXX interacts with Ku to promote DNA double-strand break repair, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc8408) was used in western blot on human samples at 1:1000 (fig s7). Science (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 3
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 3). Oncotarget (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 6
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples (fig 6). Mol Cell Biol (2015) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples . Mol Cell Biol (2015) ncbi
mouse monoclonal (G-4)
  • western blot; African green monkey; fig 4a
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in western blot on African green monkey samples (fig 4a). PLoS Pathog (2014) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples . Cancer Res (2014) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 1b
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in western blot on human samples (fig 1b). Nucleic Acids Res (2014) ncbi
mouse monoclonal (DCS-310)
  • western blot; human; 1:1000
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, DCS-310) was used in western blot on human samples at 1:1000. DNA Repair (Amst) (2014) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 3e
Santa Cruz Biotechnology Chek1 antibody (SantaCruz, sc-8408) was used in western blot on human samples (fig 3e). Nucleic Acids Res (2014) ncbi
mouse monoclonal (G-4)
  • immunoprecipitation; human; 1:100
  • western blot; human; 1:1000; fig 4a
  • western blot; mouse; 1:1000; fig 4c
In order to show that the zinc finger E-box binding homeobox 1 regulates radiosensitivity and the DNA damage response in breast cancer cells, Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in immunoprecipitation on human samples at 1:100, in western blot on human samples at 1:1000 (fig 4a) and in western blot on mouse samples at 1:1000 (fig 4c). Nat Cell Biol (2014) ncbi
mouse monoclonal (G-4)
  • western blot; human; 1:1000; fig s2
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2014) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples . Life Sci (2014) ncbi
mouse monoclonal (G-4)
  • western blot; chicken; fig 2
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in western blot on chicken samples (fig 2). Nucleic Acids Res (2014) ncbi
mouse monoclonal (DCS-310)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-56291) was used in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; 1:2000; fig 2b
Santa Cruz Biotechnology Chek1 antibody (Santa, sc-8408) was used in western blot on mouse samples at 1:2000 (fig 2b). J Biol Chem (2014) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; mouse
  • western blot; mouse
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in immunocytochemistry on mouse samples and in western blot on mouse samples . Nucleic Acids Res (2013) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 5d
Santa Cruz Biotechnology Chek1 antibody (santa cruz, sc-8408) was used in western blot on human samples (fig 5d). Nucleic Acids Res (2013) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples . J Biol Chem (2013) ncbi
mouse monoclonal (G-4)
  • western blot; chicken
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, G4) was used in western blot on chicken samples and in western blot on human samples . PLoS ONE (2013) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; 1:200
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on mouse samples at 1:200. J Biol Chem (2013) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples . DNA Repair (Amst) (2013) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, G4) was used in western blot on human samples . Nucleic Acids Res (2013) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples . Genes Cells (2012) ncbi
mouse monoclonal (G-4)
  • western blot; human
In order to investigate the regulation of Rad18 during DNA damage and the cell cycle, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, sc-8408) was used in western blot on human samples . J Cell Biol (2010) ncbi
mouse monoclonal (G-4)
  • western blot; human
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot on human samples . Cancer Res (2010) ncbi
mouse monoclonal (G-4)
  • western blot; human; loading ...; fig 4c
  • western blot; mouse; loading ...; fig 4a
Santa Cruz Biotechnology Chek1 antibody (Santa, G-4) was used in western blot on human samples (fig 4c) and in western blot on mouse samples (fig 4a). J Biol Chem (2010) ncbi
mouse monoclonal (G-4)
  • immunocytochemistry; human; fig 4
In order to show that camptothecin-induced activation of ATM requires transcription, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, G-4) was used in immunocytochemistry on human samples (fig 4). J Biol Chem (2010) ncbi
mouse monoclonal (G-4)
  • western blot; human; fig 2
In order to investigate the mechanism of proteasome-dependent RPA2 phosphorylation, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, G-4) was used in western blot on human samples (fig 2). DNA Repair (Amst) (2010) ncbi
mouse monoclonal (G-4)
  • western blot; mouse; 1:1000
Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, G4) was used in western blot on mouse samples at 1:1000. Neuro Oncol (2009) ncbi
mouse monoclonal (G-4)
  • western blot; human
In order to investigate the potential role of the proteasome in checkpoint activation and ATM/ATR signaling in response to UV light-induced DNA damage, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz Biotechnology, G-4) was used in western blot on human samples . J Biol Chem (2008) ncbi
mouse monoclonal (G-4)
  • western blot knockout validation; mouse; fig 3
In order to assess the abilities of Chk1 mutants to reverse the defects of Chk1-null cells, Santa Cruz Biotechnology Chek1 antibody (Santa Cruz, sc-8408) was used in western blot knockout validation on mouse samples (fig 3). Mol Cell Biol (2007) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2j
Abcam Chek1 antibody (Abcam, ab47318) was used in western blot on mouse samples (fig 2j). Cell Death Discov (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig st3
In order to study the DNA damage response in senescent epithelial cells, Abcam Chek1 antibody (Abcam, ab47318) was used in western blot on human samples at 1:1000 (fig st3). Nat Commun (2016) ncbi
Invitrogen
domestic rabbit monoclonal (S.48.4)
  • western blot; human; fig 3
In order to report the effects of new temozolomide analogues on glioblastoma multiforme, Invitrogen Chek1 antibody (Millipore, MA5-15145) was used in western blot on human samples (fig 3). Mol Cancer Ther (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 3k
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 3k). J Exp Clin Cancer Res (2022) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 3k
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2360) was used in western blot on human samples (fig 3k). J Exp Clin Cancer Res (2022) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig 2d, 2e
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig 2d, 2e). Am J Cancer Res (2022) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig 2g, 6e
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig 2g, 6e). Cell Rep (2022) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; loading ...; fig 2g, 6e
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples at 1:1000 (fig 2g, 6e). Cell Rep (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 2b). Sci Rep (2021) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; loading ...; fig s10a, s10b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples at 1:1000 (fig s10a, s10b). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s10a, s10b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344) was used in western blot on human samples at 1:1000 (fig s10a, s10b). Nat Commun (2021) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; loading ...; fig 1j
Cell Signaling Technology Chek1 antibody (Cell Signaling, 133D3) was used in western blot on mouse samples (fig 1j). J Clin Invest (2021) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig 13e
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples at 1:1000 (fig 13e). elife (2021) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; loading ...; fig 2f
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2G1D5) was used in western blot on human samples at 1:1000 (fig 2f). PLoS Genet (2021) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig 2f
Cell Signaling Technology Chek1 antibody (Cell Signaling, 133D3) was used in western blot on human samples at 1:1000 (fig 2f). PLoS Genet (2021) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig 1a, 1b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig 1a, 1b). Sci Rep (2021) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348S) was used in western blot on human samples (fig 4a). Sci Rep (2021) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 4a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360S) was used in western blot on human samples (fig 4a). Mol Cell (2021) ncbi
mouse monoclonal (2G1D5)
  • western blot; mouse; 1:1000; loading ...; fig s2k
  • western blot; human; 1:1000; loading ...; fig 7a, 7b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360S) was used in western blot on mouse samples at 1:1000 (fig s2k) and in western blot on human samples at 1:1000 (fig 7a, 7b). Nat Commun (2021) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 5i
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 5i). Theranostics (2021) ncbi
mouse monoclonal (2G1D5)
  • western blot; mouse; loading ...; fig 4c
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on mouse samples (fig 4c). Biol Open (2021) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2360) was used in western blot on human samples (fig 1f). JCI Insight (2021) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 1f). JCI Insight (2021) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 5h
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2360) was used in western blot on human samples (fig 5h). Mol Cell (2020) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 5h
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 133D3) was used in western blot on human samples (fig 5h). Mol Cell (2020) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:500; loading ...; fig 2h
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on mouse samples at 1:500 (fig 2h). PLoS Genet (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344) was used in western blot on human samples (fig 3b). Cells (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 3b). Cells (2020) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 4d
Cell Signaling Technology Chek1 antibody (Cell signaling, 2360S) was used in western blot on human samples (fig 4d). elife (2020) ncbi
domestic rabbit monoclonal (133D3)
  • immunocytochemistry; human; loading ...; fig 5c
  • western blot; human; loading ...; fig 5d, 6b
Cell Signaling Technology Chek1 antibody (Cell signaling, 2348S) was used in immunocytochemistry on human samples (fig 5c) and in western blot on human samples (fig 5d, 6b). elife (2020) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 3a, 3b, 3c
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2G1D5) was used in western blot on human samples (fig 3a, 3b, 3c). elife (2020) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; dogs; 1:1000; fig 4c
Cell Signaling Technology Chek1 antibody (CST, 2348) was used in western blot on dogs samples at 1:1000 (fig 4c). Cells (2020) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Chek1 antibody (Cell Signalling Technologies, 2360) was used in western blot on human samples (fig 2b). elife (2020) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology Chek1 antibody (Cell Signalling Technologies, 2348S) was used in western blot on human samples (fig 2b). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6d
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 6d). Int J Biol Sci (2019) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 1a, 5b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 1a, 5b). Mol Cell (2019) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 1a, 5b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 1a, 5b). Mol Cell (2019) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; fig 6a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on mouse samples (fig 6a). Cell Rep (2019) ncbi
mouse monoclonal (2G1D5)
  • western blot; mouse; fig 6a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on mouse samples (fig 6a). Cell Rep (2019) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 1a). Mol Cell (2019) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology Chek1 antibody (Cell Signalling, 2348) was used in western blot on human samples at 1:1000 (fig 2b). Nucleic Acids Res (2019) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology Chek1 antibody (Cell Signalling, 2360) was used in western blot on human samples at 1:1000 (fig 2b). Nucleic Acids Res (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 7a, 8c
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 7a, 8c). PLoS Genet (2019) ncbi
domestic rabbit polyclonal
  • western blot; Xenopus laevis; loading ...; fig s1k
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341L) was used in western blot on Xenopus laevis samples (fig s1k). Cell (2019) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 5d
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 5d). Genes Dev (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4e
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples at 1:1000 (fig 4e). Sci Rep (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2341S) was used in western blot on mouse samples (fig 1b). Nature (2018) ncbi
domestic rabbit monoclonal (133D3)
  • immunocytochemistry; human; loading ...; fig 2g
  • western blot; human; 1:100; loading ...; fig 2i, 6n
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in immunocytochemistry on human samples (fig 2g) and in western blot on human samples at 1:100 (fig 2i, 6n). Nucleic Acids Res (2018) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 133D3) was used in western blot on human samples (fig 1b). Oncogene (2018) ncbi
domestic rabbit monoclonal (133D3)
  • flow cytometry; mouse; loading ...; fig 5c
Cell Signaling Technology Chek1 antibody (Cell Signaling Technologies, 12268S) was used in flow cytometry on mouse samples (fig 5c). Cell Death Dis (2018) ncbi
mouse monoclonal (2G1D5)
  • other; human; loading ...; fig 4c
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig s1c
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig s1c). Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341S) was used in western blot on human samples (fig 1b). Mol Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2g
Cell Signaling Technology Chek1 antibody (CST, 2341S) was used in western blot on mouse samples (fig 2g). Nucleic Acids Res (2018) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:500; loading ...; fig 4p
Cell Signaling Technology Chek1 antibody (Cell Signaling, 133D3) was used in western blot on human samples at 1:500 (fig 4p). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:100; loading ...; fig 5d
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341S) was used in immunocytochemistry on mouse samples at 1:100 (fig 5d). Biol Reprod (2018) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 2a). Tumour Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s4a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig s4a). Genes Dev (2017) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 5c
In order to report that autosomal recessive, partial Go-Ichi-Ni-San 1 deficiency impairs DNA replication and underlies intra-uterine and postnatal growth retardation, chronic neutropenia, and natural killer cell deficiency, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2G1D5) was used in western blot on human samples (fig 5c). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; loading ...; fig 2a
  • western blot; human; fig 2c
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on mouse samples (fig 2a) and in western blot on human samples (fig 2c). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on mouse samples (fig 5a). Genes Dev (2017) ncbi
domestic rabbit monoclonal (133D3)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology Chek1 antibody (CST, 2348) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 2g
Cell Signaling Technology Chek1 antibody (Cell signaling, 2348) was used in western blot on human samples (fig 2g). Genes Dev (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 2c
In order to examine the effects of the arginine methyltransferase PRMT5 on homologous recombination-mediated double-strand break repair, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 2c). Mol Cell (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4e
In order to research the role of TOPBP1 in DNA homologous recombination, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 4e). J Cell Biol (2017) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 2a, 2b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 2a, 2b). Cell Rep (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig s4c
In order to analyze the effect of CX-5461 as a G-quadruplex DNA stabilizer, Cell Signaling Technology Chek1 antibody (Cell Signal, 2348L) was used in western blot on human samples at 1:1000 (fig s4c). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3a
In order to identify interacting proteins of TTF-1 and their role in lung adenocarcinoma cell survival., Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344) was used in western blot on human samples (fig 3a). Oncogene (2017) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 2a
Cell Signaling Technology Chek1 antibody (Cell signaling, 2360) was used in western blot on human samples (fig 2a). PLoS ONE (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:1000; loading ...; fig 6D
  • western blot; human; 1:1000; loading ...; fig 3E
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on mouse samples at 1:1000 (fig 6D) and in western blot on human samples at 1:1000 (fig 3E). Nucleic Acids Res (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig s2
In order to describe a role for NIPBL in DNA damage repair, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig s2). J Cell Sci (2017) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; loading ...; fig s2
In order to describe a role for NIPBL in DNA damage repair, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples at 1:1000 (fig s2). J Cell Sci (2017) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology Chek1 antibody (Cell signaling, 2360) was used in western blot on human samples at 1:1000 (fig 2b). Oncotarget (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2b
Cell Signaling Technology Chek1 antibody (Cell signaling, 2341) was used in western blot on human samples at 1:1000 (fig 2b). Oncotarget (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig 6c
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348S) was used in western blot on human samples at 1:1000 (fig 6c). Mol Biol Cell (2017) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 8
Cell Signaling Technology Chek1 antibody (Cell signaling, 2360) was used in western blot on human samples (fig 8). Int J Mol Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1j
In order to show that the deoxynucleoside triphosphate triphosphohydrolase SAM domain and HD domain 1 promotes the detoxification of intracellular cytostatic deoxycytidine analog cytarabine triphosphate pools, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 1j). Nat Med (2017) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:500; loading ...; fig S1D
In order to find depletion of human Cactin leads to premature sister chromatid separation, genome instability and cell proliferation arrest, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:500 (fig S1D). J Cell Sci (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig s6a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341S) was used in western blot on human samples at 1:500 (fig s6a). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1g
In order to demonstrate a role for CDC6 in cell survival and DNA replication, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 1g). elife (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:1000; loading ...; fig s2b
  • western blot; human; 1:800; fig 7e
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on mouse samples at 1:1000 (fig s2b) and in western blot on human samples at 1:800 (fig 7e). EMBO Mol Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3e
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples at 1:1000 (fig 3e). Nat Commun (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:1000; loading ...; fig s19g
Cell Signaling Technology Chek1 antibody (Cell Signaling, 133D3) was used in western blot on mouse samples at 1:1000 (fig s19g). Science (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 1b). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s2b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig s2b). Cell Death Dis (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig s2b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig s2b). Cell Death Dis (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2c
In order to elucidate the upstream mechanisms of apoptosis triggered by an anti-microtubule drug, ABT-751, Cell Signaling Technology Chek1 antibody (cell signalling, 2341) was used in western blot on human samples at 1:1000 (fig 2c). Toxicol Appl Pharmacol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
Cell Signaling Technology Chek1 antibody (Cell signaling, 2341) was used in western blot on human samples (fig 1). Nucleic Acids Res (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 3d
In order to propose that ABHD5 has a PNPLA2-independent function in regulating autophagy and tumorigenesis, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 3d). Autophagy (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 3d
In order to propose that ABHD5 has a PNPLA2-independent function in regulating autophagy and tumorigenesis, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 3d). Autophagy (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 5c
In order to assess the effect of three alpha-tubulin acetyltransferase 1-specific shRNAs on proliferation and morphology in HeLa and A549 cell lines, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 5c). Cell Death Discov (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344) was used in western blot on human samples (fig 1d). Sci Rep (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 1d). Sci Rep (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 4
Cell Signaling Technology Chek1 antibody (Signaling Technology, 2360) was used in western blot on human samples (fig 4). J Cell Mol Med (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; loading ...; fig 3e
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2G1D2) was used in western blot on human samples at 1:1000 (fig 3e). Oncotarget (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 4
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 4). PLoS Genet (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344) was used in western blot on human samples (fig 4). PLoS Genet (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig s1
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on mouse samples at 1:1000 (fig s1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:1000; loading ...; fig 5b
In order to investigate the link between NEAT1 paraspeckles, p53 biology, and tumorigenesis, Cell Signaling Technology Chek1 antibody (Cell Signaling, 133D3) was used in western blot on mouse samples at 1:1000 (fig 5b). Nat Med (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:500; loading ...; fig 4a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:500 (fig 4a). Oncotarget (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; fig 1
In order to study disruption of the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity due to immunomodulatory drugs, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2360) was used in western blot on human samples at 1:1000 (fig 1). Nat Med (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology Chek1 antibody (Cell Signaling Tech, 133D3) was used in western blot on human samples at 1:1000 (fig 3). Int J Mol Sci (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; chicken; fig s4
In order to study promotion of IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA by histone H3.3, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on chicken samples (fig s4). EMBO J (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:500; loading ...; fig 3d
In order to describe how a CHK1 inhibitor reduces the growth of radioresistant breast cancer cells, Cell Signaling Technology Chek1 antibody (Cell signaling, 133D3) was used in western blot on human samples at 1:500 (fig 3d). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 2
Cell Signaling Technology Chek1 antibody (Cell Signal, 2341) was used in western blot on mouse samples (fig 2). Cell Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 7h
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2344S) was used in western blot on human samples (fig 7h). EMBO Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2344) was used in western blot on human samples (fig 5). Cell Rep (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 2
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 2). Cell Rep (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 5
In order to study involvement in cisplatin radiosensitization of non-small cell lung cancer by the DNA damage response (DDR) pathway, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2G1D5) was used in western blot on human samples (fig 5). DNA Repair (Amst) (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 4
In order to study involvement in cisplatin radiosensitization of non-small cell lung cancer by the DNA damage response (DDR) pathway, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348S) was used in western blot on human samples (fig 4). DNA Repair (Amst) (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 133D3) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 1b
Cell Signaling Technology Chek1 antibody (cell signalling, 2348) was used in western blot on human samples (fig 1b). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig s4
In order to study APC/C(Cdh1) function, Cell Signaling Technology Chek1 antibody (Cell signalling, 2341) was used in western blot on human samples at 1:1000 (fig s4). Nucleic Acids Res (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig s2
Cell Signaling Technology Chek1 antibody (Cell Signalling, 2341) was used in western blot on human samples (fig s2). Oncotarget (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 7
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 133D3) was used in western blot on human samples (fig 7). Cell Cycle (2016) ncbi
domestic rabbit polyclonal
  • western blot; Xenopus laevis; fig S3
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on Xenopus laevis samples (fig S3). J Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1a
In order to study quinacrine-induced apoptosis, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344S) was used in western blot on human samples (fig 1a). Biochem Pharmacol (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples at 1:1000 (fig 6). Nat Commun (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig 6). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; fig s6c
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344) was used in western blot on human samples at 1:500 (fig s6c). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
In order to investigate the role of topoisomerase IIbeta-binding protein 1 in DNA repair and its contribution to cancer, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344) was used in western blot on human samples (fig 1). J Cell Biol (2016) ncbi
domestic rabbit monoclonal (133D3)
  • immunocytochemistry; mouse; 1:200; fig 5
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in immunocytochemistry on mouse samples at 1:200 (fig 5) and in western blot on mouse samples at 1:1000 (fig 5). Mol Biol Cell (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 2d
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2344P) was used in western blot on human samples (fig 2d). Nucleic Acids Res (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 3
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 3). J Cell Biol (2016) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 5b
In order to study the effect of galiellalactone in regards to cell cycle arrest and apoptosis via ATM/ATR pathway in prostate cancer cells, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 5b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; loading ...; fig 5b
In order to study the effect of galiellalactone in regards to cell cycle arrest and apoptosis via ATM/ATR pathway in prostate cancer cells, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 5b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 5
In order to study NPM-ALK-amplified cell lines resistant to ALK tyrosine kinase inhibitors, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 5). Oncogene (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig 2). Nat Commun (2015) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; fig 4
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2341) was used in western blot on human samples at 1:500 (fig 4). Nat Genet (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; fig 3a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348S) was used in western blot on mouse samples (fig 3a). Cell Rep (2015) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5d
Cell Signaling Technology Chek1 antibody (Cell Signalling, 2344) was used in western blot on human samples at 1:1000 (fig 5d). Oncogene (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 2
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348P) was used in western blot on human samples (fig 2). Aging (Albany NY) (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 8
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 8). Nucleic Acids Res (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 5
In order to characterize inhibition of gamma-irradiation-induced apoptosis of prostate cancer cells by elevated expression of hepatoma up-regulated protein, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2341) was used in western blot on human samples at 1:1000 (fig 5). J Cell Biochem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 5
In order to characterize inhibition of gamma-irradiation-induced apoptosis of prostate cancer cells by elevated expression of hepatoma up-regulated protein, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2344) was used in western blot on human samples at 1:1000 (fig 5). J Cell Biochem (2016) ncbi
domestic rabbit monoclonal (133D3)
  • immunocytochemistry; human; fig s7
Cell Signaling Technology Chek1 antibody (Cell signaling, 2348) was used in immunocytochemistry on human samples (fig s7). Nucleic Acids Res (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2344) was used in western blot on human samples at 1:1000 (fig 2). Nucleic Acids Res (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 6d
In order to investigate the role of mitochondrial ATR during the response to UV damage, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology., 2348) was used in western blot on human samples (fig 6d). Mol Cell (2015) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 6a
In order to report the effect of c-Met inhibition using neuroendocrine tumor cells, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 6a). Neuroendocrinology (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6a
In order to report the effect of c-Met inhibition using neuroendocrine tumor cells, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2341) was used in western blot on human samples (fig 6a). Neuroendocrinology (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 6
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 6). J Cell Biol (2015) ncbi
domestic rabbit monoclonal (133D3)
  • immunocytochemistry; mouse; 1:1000; fig s6
  • western blot; mouse; fig 7
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in immunocytochemistry on mouse samples at 1:1000 (fig s6) and in western blot on mouse samples (fig 7). Nat Struct Mol Biol (2015) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig s4
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig s4). Nucleic Acids Res (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 3
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 3). Nucleic Acids Res (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples . Mol Cancer Ther (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; rhesus macaque; fig 2
  • western blot; pigs ; fig 2
In order to study nuclear African swine fever virus replication, Cell Signaling Technology Chek1 antibody (Cell Signalling Technology, 2348) was used in western blot on rhesus macaque samples (fig 2) and in western blot on pigs samples (fig 2). Virus Res (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000. Cancers (Basel) (2015) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology Chek1 antibody (Cell Signaling Technologies, 2360) was used in western blot on human samples (fig 5a). PLoS Genet (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 4
Cell Signaling Technology Chek1 antibody (Cell signaling, 2348S) was used in western blot on human samples (fig 4). Mol Cell Biol (2015) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 1
Cell Signaling Technology Chek1 antibody (Cell signaling, 2360) was used in western blot on human samples (fig 1). Nucleic Acids Res (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig 4). Nat Commun (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 5
In order to characterize suppression of tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest via mangrove dolabrane-type of diterpenes tagalsins, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 133D3) was used in western blot on human samples (fig 5). Int J Cancer (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 5
Cell Signaling Technology Chek1 antibody (Cell Signaling Tech, 2348) was used in western blot on human samples (fig 5). J Biol Chem (2015) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 1
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 1
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 1
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 1). Carcinogenesis (2015) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig e4
In order to assess mutp53 as a cancer-specific drug target, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig e4). Nature (2015) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 2
In order to compare the chemosensitizing effect of nucleoside analogues in cells derived from pancreatic cancer and in osteosarcoma-derived cells, Cell Signaling Technology Chek1 antibody (Cell signaling, 2360) was used in western blot on human samples (fig 2). Oncotarget (2015) ncbi
domestic rabbit polyclonal
  • western blot; human
In order to investigate the effect of PC4 on genome stability and DNA repair, Cell Signaling Technology Chek1 antibody (NEB Cell signaling, 2344 S) was used in western blot on human samples . Oncogene (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human
In order to investigate the effect of PC4 on genome stability and DNA repair, Cell Signaling Technology Chek1 antibody (Cell signaling, 2341) was used in immunocytochemistry on human samples and in western blot on human samples . Oncogene (2016) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 2
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 2). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human
In order to report that TopBP1 and ATR inhibit the synthesis of rRNA and activate the nucleolar stress pathway, Cell Signaling Technology Chek1 antibody (Cell Signalling, 133D3) was used in western blot on human samples . Nucleic Acids Res (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; fig 4
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples at 1:1000 (fig 4). Mol Biol Cell (2015) ncbi
domestic rabbit monoclonal (133D3)
  • immunocytochemistry; mouse; fig s4
  • western blot; mouse; 1:1000; fig 3
In order to report the role of MAD2L2 in DNA repair at mammalian telomeres, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in immunocytochemistry on mouse samples (fig s4) and in western blot on mouse samples at 1:1000 (fig 3). Nature (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 1
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 4
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 4). J Cell Biol (2015) ncbi
domestic rabbit monoclonal (133D3)
  • reverse phase protein lysate microarray; human; 1:1000; fig 4
In order to identify a novel DNA2- and WRN-dependent mechanism of reversed replication fork processing and restart after prolonged genotoxic stress, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in reverse phase protein lysate microarray on human samples at 1:1000 (fig 4). J Cell Biol (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human
In order to examine the role of NF-kappaB during the human papillomavirus life cycle, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 133D3) was used in western blot on human samples . J Virol (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:100; fig 6
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on mouse samples at 1:100 (fig 6). Cell Cycle (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 6
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 6). Cell Cycle (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:10,000; fig s7
In order to determine how PAXX interacts with Ku to promote DNA double-strand break repair, Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples at 1:10,000 (fig s7). Science (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig 4B
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig 4B). Mol Med Rep (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:1000
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on mouse samples at 1:1000. Cell Death Dis (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; fig 1
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on mouse samples (fig 1). Proc Natl Acad Sci U S A (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 3
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 3). Oncotarget (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples at 1:1000. Cancer Lett (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 6
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 6). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples . DNA Repair (Amst) (2015) ncbi
domestic rabbit monoclonal (133D3)
  • flow cytometry; human; 1:100
  • immunocytochemistry; human; 1:150
  • western blot; human
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in flow cytometry on human samples at 1:100, in immunocytochemistry on human samples at 1:150 and in western blot on human samples . Cancer Res (2014) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 1b
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples (fig 1b). Nucleic Acids Res (2014) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on mouse samples . Biochim Biophys Acta (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; fig 2a
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig 2a). Oncotarget (2014) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; loading ...; fig s2d
In order to investigate the role of endonuclease G in the initiation of DNA rearrangements, Cell Signaling Technology Chek1 antibody (CellSignalling, 2348) was used in western blot on human samples at 1:1000 (fig s2d). Oncogene (2015) ncbi
domestic rabbit monoclonal (133D3)
  • immunocytochemistry; mouse; fig 3
In order to study why HSC function declines with age, Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in immunocytochemistry on mouse samples (fig 3). Nature (2014) ncbi
mouse monoclonal (2G1D5)
  • western blot; human; fig 3
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2360) was used in western blot on human samples (fig 3). Oncogene (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 3
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348S) was used in western blot on human samples (fig 3). Oncogene (2015) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; 1:1000; fig s2
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2014) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348S) was used in western blot on human samples . J Virol (2014) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples . Genes Dev (2014) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human; fig 2d
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples (fig 2d). J Biol Chem (2014) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:10,000; fig 2b
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on mouse samples at 1:10,000 (fig 2b). J Biol Chem (2014) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; mouse; 1:1000
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in western blot on mouse samples at 1:1000. J Biol Chem (2013) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human
Cell Signaling Technology Chek1 antibody (Cell Signaling Technologies, 2348) was used in western blot on human samples . PLoS ONE (2012) ncbi
domestic rabbit monoclonal (133D3)
  • immunocytochemistry; human
  • western blot; human
Cell Signaling Technology Chek1 antibody (Cell Signaling, 2348) was used in immunocytochemistry on human samples and in western blot on human samples . Cell Rep (2012) ncbi
domestic rabbit monoclonal (133D3)
  • western blot; human
Cell Signaling Technology Chek1 antibody (Cell Signaling Technology, 2348) was used in western blot on human samples . Genes Cells (2012) ncbi
Articles Reviewed
  1. Tu Q, Liu X, Yao X, Li R, Liu G, Jiang H, et al. RETSAT associates with DDX39B to promote fork restarting and resistance to gemcitabine based chemotherapy in pancreatic ductal adenocarcinoma. J Exp Clin Cancer Res. 2022;41:274 pubmed publisher
  2. Cui J, Dean D, Hornicek F, Pollock R, Hoffman R, Duan Z. ATR inhibition sensitizes liposarcoma to doxorubicin by increasing DNA damage. Am J Cancer Res. 2022;12:1577-1592 pubmed
  3. An N, Li Z, Yan X, Zhao H, Yang Y, Liu R, et al. Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice. Cell Death Discov. 2022;8:26 pubmed publisher
  4. Abt E, Le T, Dann A, Capri J, Poddar S, Lok V, et al. Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. Cell Rep. 2022;38:110236 pubmed publisher
  5. Boucher D, Kariawasam R, Burgess J, Gimenez A, Ocampo T, Ferguson B, et al. hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage. Sci Rep. 2021;11:20256 pubmed publisher
  6. Nam J, Kim A, Choi S, Kim J, Choi K, Cho S, et al. An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage. Nat Commun. 2021;12:3279 pubmed publisher
  7. Kim C, Jin J, Ye Z, Jadhav R, Gustafson C, Hu B, et al. Histone deficiency and accelerated replication stress in T cell aging. J Clin Invest. 2021;131: pubmed publisher
  8. Barger C, Chee L, Albahrani M, Munoz Trujillo C, Boghean L, Branick C, et al. Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer. elife. 2021;10: pubmed publisher
  9. Park K, Ryoo J, Jeong H, Kim M, Lee S, Hwang S, et al. Aicardi-Goutières syndrome-associated gene SAMHD1 preserves genome integrity by preventing R-loop formation at transcription-replication conflict regions. PLoS Genet. 2021;17:e1009523 pubmed publisher
  10. Ho K, Luo H, Zhu W, Tang Y. Critical role of SMG7 in activation of the ATR-CHK1 axis in response to genotoxic stress. Sci Rep. 2021;11:7502 pubmed publisher
  11. Ditano J, Donahue K, Tafe L, McCleery C, Eastman A. Sensitivity of cells to ATR and CHK1 inhibitors requires hyperactivation of CDK2 rather than endogenous replication stress or ATM dysfunction. Sci Rep. 2021;11:7077 pubmed publisher
  12. Sewastianik T, Straubhaar J, Zhao J, Samur M, Adler K, Tanton H, et al. miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms. Blood. 2021;137:1905-1919 pubmed publisher
  13. Heider M, Eichner R, Stroh J, Morath V, Kuisl A, Zecha J, et al. The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma. Mol Cell. 2021;: pubmed publisher
  14. Vaughan C, Singh S, Subler M, Windle J, Inoue K, Fry E, et al. The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3. Nat Commun. 2021;12:704 pubmed publisher
  15. Wen Y, Hou Y, Yi X, Sun S, Guo J, He X, et al. EZH2 activates CHK1 signaling to promote ovarian cancer chemoresistance by maintaining the properties of cancer stem cells. Theranostics. 2021;11:1795-1813 pubmed publisher
  16. Qiao F, Law H, Krieger K, Clement E, Xiao Y, Buckley S, et al. Ctdp1 deficiency leads to early embryonic lethality in mice and defects in cell cycle progression in MEFs. Biol Open. 2021;10: pubmed publisher
  17. Tothova Z, Valton A, Gorelov R, Vallurupalli M, Krill Burger J, Holmes A, et al. Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML. JCI Insight. 2021;6: pubmed publisher
  18. Hewitt G, Borel V, Segura Bayona S, Takaki T, Ruis P, Bellelli R, et al. Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Mol Cell. 2020;: pubmed publisher
  19. Wang Y, Luo M, Chen Y, Wang Y, Zhang B, Ren Z, et al. ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. Cancer Res. 2021;81:174-186 pubmed publisher
  20. Dewhurst M, Ow J, Zafer G, Van Hul N, Wollmann H, Bisteau X, et al. Loss of hepatocyte cell division leads to liver inflammation and fibrosis. PLoS Genet. 2020;16:e1009084 pubmed publisher
  21. Moses N, Zhang M, Wu J, Hu C, Xiang S, Geng X, et al. HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1. Cells. 2020;9: pubmed publisher
  22. Brunner A, Suryo Rahmanto A, Johansson H, Franco M, Viiliäinen J, Gazi M, et al. PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer. elife. 2020;9: pubmed publisher
  23. Ta H, Dworak N, Ivey M, Roller D, Gioeli D. AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR-CHK2 interaction and prostate cancer survival. elife. 2020;9: pubmed publisher
  24. Shinada M, Kato D, Kamoto S, Yoshimoto S, Tsuboi M, Yoshitake R, et al. PDPN Is Expressed in Various Types of Canine Tumors and Its Silencing Induces Apoptosis and Cell Cycle Arrest in Canine Malignant Melanoma. Cells. 2020;9: pubmed publisher
  25. Lochab S, Singh Y, Sengupta S, Nandicoori V. Mycobacterium tuberculosis exploits host ATM kinase for survival advantage through SecA2 secretome. elife. 2020;9: pubmed publisher
  26. Pothuraju R, Rachagani S, Krishn S, Chaudhary S, Nimmakayala R, Siddiqui J, et al. Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance. Mol Cancer. 2020;19:37 pubmed publisher
  27. Li P, Meng Y, Wang Y, Li J, Lam M, Wang L, et al. Nuclear localization of Desmoplakin and its involvement in telomere maintenance. Int J Biol Sci. 2019;15:2350-2362 pubmed publisher
  28. Colomer C, Margalef P, Villanueva A, Vert A, Pecharroman I, Sole L, et al. IKKα Kinase Regulates the DNA Damage Response and Drives Chemo-resistance in Cancer. Mol Cell. 2019;75:669-682.e5 pubmed publisher
  29. Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed publisher
  30. Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed publisher
  31. Li S, Lavagnino Z, Lemaçon D, Kong L, Ustione A, Ng X, et al. Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection. Mol Cell. 2019;74:1123-1137.e6 pubmed publisher
  32. Alfano L, Caporaso A, Altieri A, Dell Aquila M, Landi C, Bini L, et al. Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation. Nucleic Acids Res. 2019;47:4068-4085 pubmed publisher
  33. Wang J, Chan B, Tong M, Paung Y, Jo U, MARTIN D, et al. Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway. PLoS Genet. 2019;15:e1007983 pubmed publisher
  34. Sparks J, Chistol G, Gao A, Raschle M, Larsen N, Mann M, et al. The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair. Cell. 2019;176:167-181.e21 pubmed publisher
  35. Moquin D, Genois M, Zhang J, Ouyang J, Yadav T, Buisson R, et al. Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination. Genes Dev. 2019;33:75-89 pubmed publisher
  36. Kim D, Kim S, Oh Y, Park S, Jeon Y, Kim H, et al. AIMP3 Deletion Induces Acute Radiation Syndrome-like Phenotype in Mice. Sci Rep. 2018;8:15025 pubmed publisher
  37. Saldivar J, Hamperl S, Bocek M, Chung M, Bass T, Cisneros Soberanis F, et al. An intrinsic S/G2 checkpoint enforced by ATR. Science. 2018;361:806-810 pubmed publisher
  38. Mirman Z, Lottersberger F, Takai H, Kibe T, Gong Y, Takai K, et al. 53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in. Nature. 2018;560:112-116 pubmed publisher
  39. Kannan A, Bhatia K, Branzei D, Gangwani L. Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy. Nucleic Acids Res. 2018;46:8326-8346 pubmed publisher
  40. Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, et al. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018;37:4941-4954 pubmed publisher
  41. Salomè M, Magee A, Yalla K, Chaudhury S, Sarrou E, Carmody R, et al. A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling. Cell Death Dis. 2018;9:443 pubmed publisher
  42. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  43. Mohamed T, Ang Y, Radzinsky E, Zhou P, Huang Y, Elfenbein A, et al. Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration. Cell. 2018;173:104-116.e12 pubmed publisher
  44. Huang T, Fowler F, Chen C, Shen Z, SLECKMAN B, Tyler J. The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells. Mol Cell. 2018;69:879-892.e5 pubmed publisher
  45. Zhou Z, Wang L, Ge F, Gong P, Wang H, Wang F, et al. Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis. Nucleic Acids Res. 2018;46:3468-3486 pubmed publisher
  46. Wang Y, Hariharan A, Bastianello G, Toyama Y, Shivashankar G, Foiani M, et al. DNA damage causes rapid accumulation of phosphoinositides for ATR signaling. Nat Commun. 2017;8:2118 pubmed publisher
  47. Hu J, Sun F, Handel M. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018;98:102-114 pubmed publisher
  48. Paculova H, Kramara J, Simečková S, Fedr R, Soucek K, Hylse O, et al. BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors. Tumour Biol. 2017;39:1010428317727479 pubmed publisher
  49. Natsume T, Nishimura K, Minocherhomji S, Bhowmick R, Hickson I, Kanemaki M. Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis. Genes Dev. 2017;31:816-829 pubmed publisher
  50. Cottineau J, Kottemann M, Lach F, Kang Y, Vély F, Deenick E, et al. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency. J Clin Invest. 2017;127:1991-2006 pubmed publisher
  51. Singh S, Vaughan C, Frum R, Grossman S, Deb S, Palit Deb S. Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication. J Clin Invest. 2017;127:1839-1855 pubmed publisher
  52. Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard Levin Z, et al. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev. 2017;31:463-480 pubmed publisher
  53. Okazaki A, Gameiro P, Christodoulou D, Laviollette L, Schneider M, Chaves F, et al. Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers. J Clin Invest. 2017;127:1631-1645 pubmed publisher
  54. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  55. Leung J, Makharashvili N, Agarwal P, Chiu L, Pourpre R, Cammarata M, et al. ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair. Genes Dev. 2017;31:260-274 pubmed publisher
  56. Clarke T, Sanchez Bailon M, Chiang K, Reynolds J, Herrero Ruiz J, Bandeiras T, et al. PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination. Mol Cell. 2017;65:900-916.e7 pubmed publisher
  57. Liu Y, Cussiol J, Dibitetto D, Sims J, Twayana S, Weiss R, et al. TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9. J Cell Biol. 2017;216:623-639 pubmed publisher
  58. Karanika S, Karantanos T, Li L, Wang J, Park S, Yang G, et al. Targeting DNA Damage Response in Prostate Cancer by Inhibiting Androgen Receptor-CDC6-ATR-Chk1 Signaling. Cell Rep. 2017;18:1970-1981 pubmed publisher
  59. Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O Neil N, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nat Commun. 2017;8:14432 pubmed publisher
  60. Liu Z, Yanagisawa K, Griesing S, Iwai M, Kano K, Hotta N, et al. TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas. Oncogene. 2017;36:3740-3748 pubmed publisher
  61. Shin S, Song J, Hwang B, Noh D, Park S, Kim W, et al. HSPA6 augments garlic extract-induced inhibition of proliferation, migration, and invasion of bladder cancer EJ cells; Implication for cell cycle dysregulation, signaling pathway alteration, and transcription factor-associated MMP-9 regulation. PLoS ONE. 2017;12:e0171860 pubmed publisher
  62. Tu Y, Liu H, Zhu X, Shen H, Ma X, Wang F, et al. Ataxin-3 promotes genome integrity by stabilizing Chk1. Nucleic Acids Res. 2017;45:4532-4549 pubmed publisher
  63. Bot C, Pfeiffer A, Giordano F, Manjeera D, Dantuma N, Ström L. Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage. J Cell Sci. 2017;130:1134-1146 pubmed publisher
  64. Reich T, Switzeny O, Renovanz M, Sommer C, Kaina B, Christmann M, et al. Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome. Oncotarget. 2017;8:15071-15084 pubmed publisher
  65. Gong Y, Handa N, Kowalczykowski S, de Lange T. PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017;31:46-58 pubmed publisher
  66. Flanagan A, Stavenschi E, Basavaraju S, Gaboriau D, Hoey D, Morrison C. Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification. Mol Biol Cell. 2017;28:736-745 pubmed publisher
  67. Guenat D, Merla G, Deconinck E, Borg C, Rohrlich P. DNA damage response defect in Williams-Beuren syndrome. Int J Mol Med. 2017;39:622-628 pubmed publisher
  68. Herold N, Rudd S, Ljungblad L, Sanjiv K, Myrberg I, Paulin C, et al. Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies. Nat Med. 2017;23:256-263 pubmed publisher
  69. Zanini I, Soneson C, Lorenzi L, Azzalin C. Human cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. J Cell Sci. 2017;130:767-778 pubmed publisher
  70. Zhang H, Sun L, Wang K, Wu D, Trappio M, Witting C, et al. Loss of H3K9me3 Correlates with ATM Activation and Histone H2AX Phosphorylation Deficiencies in Hutchinson-Gilford Progeria Syndrome. PLoS ONE. 2016;11:e0167454 pubmed publisher
  71. Shibata E, Kiran M, Shibata Y, Singh S, Kiran S, Dutta A. Two subunits of human ORC are dispensable for DNA replication and proliferation. elife. 2016;5: pubmed publisher
  72. Benkafadar N, Menardo J, Bourien J, Nouvian R, François F, Decaudin D, et al. Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy. EMBO Mol Med. 2017;9:7-26 pubmed publisher
  73. Kotsantis P, Silva L, Irmscher S, Jones R, Folkes L, Gromak N, et al. Increased global transcription activity as a mechanism of replication stress in cancer. Nat Commun. 2016;7:13087 pubmed publisher
  74. Murai J, Feng Y, Yu G, Ru Y, Tang S, Shen Y, et al. Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition. Oncotarget. 2016;7:76534-76550 pubmed publisher
  75. Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  76. Bridges K, Chen X, Liu H, Rock C, Buchholz T, Shumway S, et al. MK-8776, a novel chk1 kinase inhibitor, radiosensitizes p53-defective human tumor cells. Oncotarget. 2016;7:71660-71672 pubmed publisher
  77. Narayanaswamy P, Tkachuk S, Haller H, Dumler I, Kiyan Y. CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling. Cell Death Dis. 2016;7:e2383 pubmed publisher
  78. Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
  79. Kehrli K, Phelps M, Lazarchuk P, Chen E, Monnat R, Sidorova J. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. J Biol Chem. 2016;291:24487-24503 pubmed
  80. Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  81. Peng Y, Miao H, Wu S, Yang W, Zhang Y, Xie G, et al. ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2. Autophagy. 2016;12:2167-2182 pubmed
  82. Chien J, Tsen S, Chien C, Liu H, Tung C, Lin C. ?TAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells. Cell Death Discov. 2016;2:16006 pubmed publisher
  83. Nagano T, Nakano M, Nakashima A, Onishi K, Yamao S, Enari M, et al. Identification of cellular senescence-specific genes by comparative transcriptomics. Sci Rep. 2016;6:31758 pubmed publisher
  84. Ah Koon L, Lesage D, Lemadre E, Souissi I, Fagard R, Varin Blank N, et al. Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells. J Cell Mol Med. 2016;20:1956-65 pubmed publisher
  85. Prince E, Balakrishnan I, Shah M, Mulcahy Levy J, Griesinger A, Alimova I, et al. Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma. Oncotarget. 2016;7:53881-53894 pubmed publisher
  86. Morales J, Richard P, Patidar P, Motea E, Dang T, Manley J, et al. XRN2 Links Transcription Termination to DNA Damage and Replication Stress. PLoS Genet. 2016;12:e1006107 pubmed publisher
  87. Yang C, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, et al. Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells. Nat Commun. 2016;7:12135 pubmed publisher
  88. Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, et al. p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. Nat Med. 2016;22:861-8 pubmed publisher
  89. Heckler M, Zeleke T, Divekar S, Fernandez A, Tiek D, Woodrick J, et al. Antimitotic activity of DY131 and the estrogen-related receptor beta 2 (ERRβ2) splice variant in breast cancer. Oncotarget. 2016;7:47201-47220 pubmed publisher
  90. Eichner R, Heider M, Fernández Sáiz V, van Bebber F, Garz A, Lemeer S, et al. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016;22:735-43 pubmed publisher
  91. Ikeuchi M, Fukumoto Y, Honda T, Kuga T, Saito Y, Yamaguchi N, et al. v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage. Int J Mol Sci. 2016;17: pubmed publisher
  92. Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed publisher
  93. Romanello M, Schiavone D, Frey A, Sale J. Histone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA. EMBO J. 2016;35:1452-64 pubmed publisher
  94. Zhang Y, Lai J, Du Z, Gao J, Yang S, Gorityala S, et al. Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress. Oncotarget. 2016;7:34688-702 pubmed publisher
  95. Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, et al. Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. Oncotarget. 2016;7:34785-99 pubmed publisher
  96. Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed publisher
  97. Choe K, Nicolae C, Constantin D, Imamura Kawasawa Y, Delgado Diaz M, De S, et al. HUWE1 interacts with PCNA to alleviate replication stress. EMBO Rep. 2016;17:874-86 pubmed publisher
  98. Huang C, Cheng J, Bawa Khalfe T, Yao X, Chin Y, Yeh E. SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability. Cell Rep. 2016;15:147-157 pubmed publisher
  99. Ribeyre C, Zellweger R, Chauvin M, Bec N, Larroque C, Lopes M, et al. Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks. Cell Rep. 2016;15:300-9 pubmed publisher
  100. Sears C, Cooney S, Chin Sinex H, Mendonca M, Turchi J. DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer. DNA Repair (Amst). 2016;40:35-46 pubmed publisher
  101. Rai R, Chen Y, Lei M, Chang S. TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions. Nat Commun. 2016;7:10881 pubmed publisher
  102. Kemp M, Sancar A. ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress. J Biol Chem. 2016;291:9330-42 pubmed publisher
  103. Ercilla A, Llopis A, Feu S, Aranda S, Ernfors P, Freire R, et al. New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress. Nucleic Acids Res. 2016;44:4745-62 pubmed publisher
  104. Tepper S, Jeschke J, Böttcher K, Schmidt A, Davari K, Müller P, et al. PARP activation promotes nuclear AID accumulation in lymphoma cells. Oncotarget. 2016;7:13197-208 pubmed publisher
  105. Köhler C, Koalick D, Fabricius A, Parplys A, Borgmann K, Pospiech H, et al. Cdc45 is limiting for replication initiation in humans. Cell Cycle. 2016;15:974-85 pubmed publisher
  106. Aparicio T, Baer R, Gottesman M, Gautier J. MRN, CtIP, and BRCA1 mediate repair of topoisomerase II-DNA adducts. J Cell Biol. 2016;212:399-408 pubmed publisher
  107. Cekan P, Hasegawa K, Pan Y, Tubman E, Odde D, Chen J, et al. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Mol Biol Cell. 2016;27:1346-57 pubmed publisher
  108. Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  109. Franz A, Pirson P, Pilger D, Halder S, Achuthankutty D, Kashkar H, et al. Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression. Nat Commun. 2016;7:10612 pubmed publisher
  110. Soriano A, París Coderch L, Jubierre L, Martínez A, Zhou X, Piskareva O, et al. MicroRNA-497 impairs the growth of chemoresistant neuroblastoma cells by targeting cell cycle, survival and vascular permeability genes. Oncotarget. 2016;7:9271-87 pubmed publisher
  111. Nassour J, Martien S, Martin N, Deruy E, Tomellini E, Malaquin N, et al. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells. Nat Commun. 2016;7:10399 pubmed publisher
  112. Walter D, Hoffmann S, Komseli E, Rappsilber J, Gorgoulis V, Sørensen C. SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication. Nat Commun. 2016;7:10530 pubmed publisher
  113. Moudry P, Watanabe K, Wolanin K, Bartkova J, Wassing I, Watanabe S, et al. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. J Cell Biol. 2016;212:281-8 pubmed publisher
  114. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  115. Ma X, Lin F, Wang Z, Hu M, Huang L, Meng T, et al. Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility. Mol Biol Cell. 2016;27:768-75 pubmed publisher
  116. Baude A, Aaes T, Zhai B, Al Nakouzi N, Oo H, Daugaard M, et al. Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination. Nucleic Acids Res. 2016;44:2214-26 pubmed publisher
  117. Hoffmann S, Smedegaard S, Nakamura K, Mortuza G, Räschle M, Ibañez de Opakua A, et al. TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J Cell Biol. 2016;212:63-75 pubmed publisher
  118. Su X, Yan H, Huang Y, Yun H, Zeng B, Wang E, et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep. 2015;5:18588 pubmed publisher
  119. García V, Lara Chica M, Cantarero I, Sterner O, Calzado M, Muñoz E. Galiellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells. Oncotarget. 2016;7:4490-506 pubmed publisher
  120. Ceccon M, Merlo M, Mologni L, Poggio T, Varesio L, Menotti M, et al. Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency. Oncogene. 2016;35:3854-3865 pubmed publisher
  121. Tollenaere M, Villumsen B, Blasius M, Nielsen J, Wagner S, Bartek J, et al. p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1. Nat Commun. 2015;6:10075 pubmed publisher
  122. Harley M, Murina O, Leitch A, Higgs M, Bicknell L, Yigit G, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nat Genet. 2016;48:36-43 pubmed publisher
  123. Lee S, Bohrson C, Pike A, Wheelan S, Greider C. ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells. Cell Rep. 2015;13:1623-32 pubmed publisher
  124. Funauchi Y, Tanikawa C, Yi Lo P, Mori J, Daigo Y, Takano A, et al. Regulation of iron homeostasis by the p53-ISCU pathway. Sci Rep. 2015;5:16497 pubmed publisher
  125. Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed publisher
  126. Waye S, Naeem A, Choudhry M, Parasido E, Tricoli L, Sivakumar A, et al. The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells. Aging (Albany NY). 2015;7:854-68 pubmed
  127. Yu Z, Huang Y, Shieh S. Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation. Nucleic Acids Res. 2016;44:1133-50 pubmed publisher
  128. Hassan M, El Khattouti A, Ejaeidi A, Ma T, Day W, Espinoza I, et al. Elevated Expression of Hepatoma Up-Regulated Protein Inhibits γ-Irradiation-Induced Apoptosis of Prostate Cancer Cells. J Cell Biochem. 2016;117:1308-18 pubmed publisher
  129. Graindorge D, Martineau S, Machon C, Arnoux P, Guitton J, Francesconi S, et al. Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication. PLoS ONE. 2015;10:e0140645 pubmed publisher
  130. Meyer S, Krebs S, Thirion C, Blum H, Krause S, Pfaffl M. Tumor Necrosis Factor Alpha and Insulin-Like Growth Factor 1 Induced Modifications of the Gene Expression Kinetics of Differentiating Skeletal Muscle Cells. PLoS ONE. 2015;10:e0139520 pubmed publisher
  131. Castella M, Jacquemont C, Thompson E, Yeo J, Cheung R, Huang J, et al. FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2. PLoS Genet. 2015;11:e1005563 pubmed publisher
  132. Saquilabon Cruz G, Kong X, Silva B, Khatibzadeh N, Thai R, Berns M, et al. Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites. Nucleic Acids Res. 2016;44:e27 pubmed publisher
  133. Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
  134. Hilton B, Li Z, Musich P, Wang H, Cartwright B, SERRANO M, et al. ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. Mol Cell. 2015;60:35-46 pubmed publisher
  135. Reuther C, Heinzle V, Spampatti M, Vlotides G, de Toni E, Spöttl G, et al. Cabozantinib and Tivantinib, but Not INC280, Induce Antiproliferative and Antimigratory Effects in Human Neuroendocrine Tumor Cells in vitro: Evidence for 'Off-Target' Effects Not Mediated by c-Met Inhibition. Neuroendocrinology. 2016;103:383-401 pubmed publisher
  136. Pedersen R, Kruse T, Nilsson J, Oestergaard V, Lisby M. TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells. J Cell Biol. 2015;210:565-82 pubmed publisher
  137. Hartlerode A, Morgan M, Wu Y, Buis J, Ferguson D. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 2015;22:736-43 pubmed publisher
  138. Zuazua Villar P, Ganesh A, Phear G, Gagou M, Meuth M. Extensive RPA2 hyperphosphorylation promotes apoptosis in response to DNA replication stress in CHK1 inhibited cells. Nucleic Acids Res. 2015;43:9776-87 pubmed publisher
  139. Lee K, Im J, Shibata E, Park J, Handa N, Kowalczykowski S, et al. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015;6:7744 pubmed publisher
  140. Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa Ichinose T, Miura D, et al. The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis. Mol Cancer Ther. 2015;14:2332-42 pubmed publisher
  141. Simões M, Martins C, Ferreira F. Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus. Virus Res. 2015;210:1-7 pubmed publisher
  142. Simpson D, Lemonie N, Morgan D, Gaddameedhi S, Kaufmann W. Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity. Cancers (Basel). 2015;7:1072-90 pubmed publisher
  143. Loveless T, Topacio B, Vashisht A, Galaang S, Ulrich K, Young B, et al. DNA Damage Regulates Translation through β-TRCP Targeting of CReP. PLoS Genet. 2015;11:e1005292 pubmed publisher
  144. Specks J, Lecona E, Lopez Contreras A, Fernandez Capetillo O. A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development. Mol Cell Biol. 2015;35:2910-7 pubmed publisher
  145. Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed publisher
  146. Ahn J, Kim S, Na W, Baek S, Kim J, Min K, et al. SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase. Nucleic Acids Res. 2015;43:6321-33 pubmed publisher
  147. Tomas Roca L, Tsaalbi Shtylik A, Jansen J, Singh M, Epstein J, Altunoglu U, et al. De novo mutations in PLXND1 and REV3L cause Möbius syndrome. Nat Commun. 2015;6:7199 pubmed publisher
  148. Neumann J, Yang Y, Köhler R, Giaisi M, Witzens Harig M, Liu D, et al. Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest. Int J Cancer. 2015;137:2739-48 pubmed publisher
  149. Hollingworth R, Skalka G, Stewart G, Hislop A, Blackbourn D, Grand R. Activation of DNA Damage Response Pathways during Lytic Replication of KSHV. Viruses. 2015;7:2908-27 pubmed publisher
  150. Xu Y, Wu X, Her C. hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ. J Biol Chem. 2015;290:18545-58 pubmed publisher
  151. Park S, Shim J, Park H, Eum D, Park M, Mi Yi J, et al. MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B. Oncogene. 2016;35:1292-301 pubmed publisher
  152. Chou W, Hu L, Hsiung C, Shen C. Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway. Carcinogenesis. 2015;36:832-40 pubmed publisher
  153. Alexandrova E, Yallowitz A, Li D, Xu S, Schulz R, Proia D, et al. Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment. Nature. 2015;523:352-6 pubmed publisher
  154. Saini P, Li Y, Dobbelstein M. Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress. Oncotarget. 2015;6:13072-87 pubmed
  155. Mortusewicz O, Evers B, Helleday T. PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites. Oncogene. 2016;35:761-70 pubmed publisher
  156. Teasley D, Parajuli S, Nguyen M, Moore H, Alspach E, Lock Y, et al. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand. J Biol Chem. 2015;290:15133-45 pubmed publisher
  157. Sokka M, Rilla K, Miinalainen I, Pospiech H, Syväoja J. High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation. Nucleic Acids Res. 2015;43:4975-89 pubmed publisher
  158. Mackay D, Ullman K. ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission. Mol Biol Cell. 2015;26:2217-26 pubmed publisher
  159. Boersma V, Moatti N, Segura Bayona S, Peuscher M, van der Torre J, Wevers B, et al. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection. Nature. 2015;521:537-540 pubmed publisher
  160. Kemp M, Lindsey Boltz L, Sancar A. UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1). J Biol Chem. 2015;290:12184-94 pubmed publisher
  161. Wang B, Wu S, Tang S, Lai C, Ou C, Wu M, et al. Benzo[a]pyrene-induced cell cycle progression occurs via ERK-induced Chk1 pathway activation in human lung cancer cells. Mutat Res. 2015;773:1-8 pubmed publisher
  162. Zellweger R, Dalcher D, Mutreja K, Berti M, Schmid J, Herrador R, et al. Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells. J Cell Biol. 2015;208:563-79 pubmed publisher
  163. Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, et al. DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol. 2015;208:545-62 pubmed publisher
  164. Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed publisher
  165. Ekumi K, Paculova H, Lenasi T, Pospichalova V, Bösken C, Rybarikova J, et al. Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex. Nucleic Acids Res. 2015;43:2575-89 pubmed publisher
  166. Parameswaran B, Chiang H, Lu Y, Coates J, Deng C, Baer R, et al. Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection. Cell Cycle. 2015;14:437-48 pubmed publisher
  167. Lindsey Boltz L, Kemp M, Capp C, Sancar A. RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling. Cell Cycle. 2015;14:99-108 pubmed publisher
  168. Kehrli K, Sidorova J. Mitomycin C reduces abundance of replication forks but not rates of fork progression in primary and transformed human cells. Oncoscience. 2014;1:540-555 pubmed
  169. Ochi T, Blackford A, Coates J, Jhujh S, Mehmood S, Tamura N, et al. DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science. 2015;347:185-188 pubmed publisher
  170. Xia J, Chen S, Lv Y, Lu L, Hu W, Zhou Y. ZGDHu-1 induces Gâ‚‚/M phase arrest and apoptosis in Kasumi-1 cells. Mol Med Rep. 2015;11:3398-404 pubmed publisher
  171. Li P, Ma X, Adams I, Yuan P. A tight control of Rif1 by Oct4 and Smad3 is critical for mouse embryonic stem cell stability. Cell Death Dis. 2015;6:e1588 pubmed publisher
  172. Liu E, Xu N, O Prey J, Lao L, Joshi S, Long J, et al. Loss of autophagy causes a synthetic lethal deficiency in DNA repair. Proc Natl Acad Sci U S A. 2015;112:773-8 pubmed publisher
  173. Smith Roe S, Nakamura J, Holley D, Chastain P, Rosson G, Simpson D, et al. SWI/SNF complexes are required for full activation of the DNA-damage response. Oncotarget. 2015;6:732-45 pubmed
  174. Zanotto Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed publisher
  175. Ray Chaudhuri A, Ahuja A, Herrador R, Lopes M. Poly(ADP-ribosyl) glycohydrolase prevents the accumulation of unusual replication structures during unperturbed S phase. Mol Cell Biol. 2015;35:856-65 pubmed publisher
  176. Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
  177. Sekimoto T, Oda T, Kurashima K, Hanaoka F, Yamashita T. Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication. Mol Cell Biol. 2015;35:699-715 pubmed publisher
  178. Sowd G, Mody D, Eggold J, Cortez D, Friedman K, Fanning E. SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication products. PLoS Pathog. 2014;10:e1004536 pubmed publisher
  179. Ramirez Y, Mladek A, Phillips R, Gynther M, Rautio J, Ross A, et al. Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth. Mol Cancer Ther. 2015;14:111-9 pubmed publisher
  180. Kawasumi M, Bradner J, Tolliday N, Thibodeau R, Sloan H, Brummond K, et al. Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity. Cancer Res. 2014;74:7534-45 pubmed publisher
  181. Zhu M, Zhao H, Liao J, Xu X. HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability. Nucleic Acids Res. 2014;42:13074-81 pubmed publisher
  182. Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed publisher
  183. Martino Echarri E, Henderson B, Brocardo M. Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy. Oncotarget. 2014;5:9889-900 pubmed
  184. Schmidt L, Wiedner M, Velimezi G, Prochazkova J, Owusu M, Bauer S, et al. ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress. DNA Repair (Amst). 2014;24:122-130 pubmed publisher
  185. Smith S, Petrova A, Madden M, Wang H, Pan Y, Warren M, et al. A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response. Nucleic Acids Res. 2014;42:11517-27 pubmed publisher
  186. Gole B, Baumann C, Mian E, Ireno C, Wiesmuller L. Endonuclease G initiates DNA rearrangements at the MLL breakpoint cluster upon replication stress. Oncogene. 2015;34:3391-401 pubmed publisher
  187. Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
  188. Flach J, Bakker S, Mohrin M, Conroy P, Pietras E, Reynaud D, et al. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 2014;512:198-202 pubmed publisher
  189. Wang W, Catto J, Meuth M. Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors. Oncogene. 2015;34:2887-96 pubmed publisher
  190. Fernandez Vidal A, Guitton Sert L, Cadoret J, Drac M, Schwob E, Baldacci G, et al. A role for DNA polymerase ? in the timing of DNA replication. Nat Commun. 2014;5:4285 pubmed publisher
  191. Adeyemi R, Pintel D. The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice. J Virol. 2014;88:10189-99 pubmed publisher
  192. Sarbajna S, Davies D, West S. Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe. Genes Dev. 2014;28:1124-36 pubmed publisher
  193. Yang X, Xu W, Hu Z, Zhang Y, Xu N. Chk1 is required for the metaphase-anaphase transition via regulating the expression and localization of Cdc20 and Mad2. Life Sci. 2014;106:12-8 pubmed publisher
  194. Fukumoto Y, Morii M, Miura T, Kubota S, Ishibashi K, Honda T, et al. Src family kinases promote silencing of ATR-Chk1 signaling in termination of DNA damage checkpoint. J Biol Chem. 2014;289:12313-29 pubmed publisher
  195. Frankenberger S, Davari K, Fischer Burkart S, Böttcher K, Tomi N, Zimber Strobl U, et al. Checkpoint kinase 1 negatively regulates somatic hypermutation. Nucleic Acids Res. 2014;42:3666-74 pubmed publisher
  196. Belanger F, Rajotte V, Drobetsky E. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts. PLoS ONE. 2014;9:e85294 pubmed publisher
  197. Lindsey Boltz L, Kemp M, Reardon J, DEROCCO V, Iyer R, Modrich P, et al. Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system. J Biol Chem. 2014;289:5074-82 pubmed publisher
  198. Luebben S, Kawabata T, Akre M, Lee W, Johnson C, O Sullivan M, et al. Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res. 2013;41:10283-97 pubmed publisher
  199. Tomida J, Itaya A, Shigechi T, Unno J, Uchida E, Ikura M, et al. A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. Nucleic Acids Res. 2013;41:6930-41 pubmed publisher
  200. Hassan B, Lindsey Boltz L, Kemp M, Sancar A. Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint response. J Biol Chem. 2013;288:18903-10 pubmed publisher
  201. Tuul M, Kitao H, Iimori M, Matsuoka K, Kiyonari S, Saeki H, et al. Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance. PLoS ONE. 2013;8:e55361 pubmed publisher
  202. Rass E, Chandramouly G, Zha S, Alt F, Xie A. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. J Biol Chem. 2013;288:7086-95 pubmed publisher
  203. Ogiwara H, Kohno T. CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes. PLoS ONE. 2012;7:e52810 pubmed publisher
  204. Crabbe L, Cesare A, Kasuboski J, Fitzpatrick J, Karlseder J. Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly. Cell Rep. 2012;2:1521-9 pubmed publisher
  205. Sidorova J, Kehrli K, Mao F, Monnat R. Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling. DNA Repair (Amst). 2013;12:128-39 pubmed publisher
  206. Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed publisher
  207. Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, et al. CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication. Genes Cells. 2012;17:962-70 pubmed publisher
  208. Day T, Palle K, Barkley L, Kakusho N, Zou Y, Tateishi S, et al. Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication. J Cell Biol. 2010;191:953-66 pubmed publisher
  209. Mao F, Sidorova J, Lauper J, Emond M, Monnat R. The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage. Cancer Res. 2010;70:6548-55 pubmed publisher
  210. Li D, Ohshiro K, Khan M, Kumar R. Requirement of MTA1 in ATR-mediated DNA damage checkpoint function. J Biol Chem. 2010;285:19802-12 pubmed publisher
  211. Sakasai R, Teraoka H, Takagi M, Tibbetts R. Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison. J Biol Chem. 2010;285:15201-8 pubmed publisher
  212. Sakasai R, Teraoka H, Tibbetts R. Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin. DNA Repair (Amst). 2010;9:76-82 pubmed publisher
  213. Li L, Dutra A, Pak E, Labrie J, Gerstein R, Pandolfi P, et al. EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors. Neuro Oncol. 2009;11:9-21 pubmed publisher
  214. Sakasai R, Tibbetts R. RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage. J Biol Chem. 2008;283:13549-55 pubmed publisher
  215. Niida H, Katsuno Y, Banerjee B, Hande M, Nakanishi M. Specific role of Chk1 phosphorylations in cell survival and checkpoint activation. Mol Cell Biol. 2007;27:2572-81 pubmed