This is a Validated Antibody Database (VAD) review about rat Cdk7, based on 7 published articles (read how Labome selects the articles), using Cdk7 antibody in all methods. It is aimed to help Labome visitors find the most suited Cdk7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cdk7 synonym: cyclin-dependent kinase 7; LOW QUALITY PROTEIN: cyclin-dependent kinase 7; 39 protein kinase; CAK; CDK-activating kinase 1; P39 Mo15; TFIIH basal transcription factor complex kinase subunit; cell division protein kinase 7; cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)

Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • immunoprecipitation; human; loading ...; fig 4b
Santa Cruz Biotechnology Cdk7 antibody (Santa Cruz, SC-7344) was used in immunoprecipitation on human samples (fig 4b). Nat Commun (2017) ncbi
mouse monoclonal (C-4)
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology Cdk7 antibody (Santa Cruz, C-4) was used in western blot on human samples (fig 3a). J Virol (2016) ncbi
mouse monoclonal (MO-1)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Cdk7 antibody (SCBT, MO-1) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (C-5)
  • western blot; mouse; fig s1h
  • western blot; human; fig s1h
In order to study the effects of cyclin-dependent kinase 7 inhibitors on MYC proteins, Santa Cruz Biotechnology Cdk7 antibody (Santa, sc-365075) was used in western blot on mouse samples (fig s1h) and in western blot on human samples (fig s1h). Cell (2014) ncbi
mouse monoclonal (C-4)
  • immunoprecipitation; human
  • western blot; human
Santa Cruz Biotechnology Cdk7 antibody (Santa, sc-7344) was used in immunoprecipitation on human samples and in western blot on human samples . Mol Cell Biol (2014) ncbi
Cell Signaling Technology
mouse monoclonal (MO1)
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology Cdk7 antibody (Cell Signaling, 2916P) was used in western blot on human samples (fig 1c). Mol Cell (2017) ncbi
mouse monoclonal (MO1)
  • western blot; human
Cell Signaling Technology Cdk7 antibody (Cell Signaling, MO1) was used in western blot on human samples . J Virol (2014) ncbi
Articles Reviewed
  1. Liao P, Zeng S, Zhou X, Chen T, Zhou F, Cao B, et al. Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. Mol Cell. 2017;68:1134-1146.e6 pubmed publisher
  2. Cayrol F, Praditsuktavorn P, Fernando T, Kwiatkowski N, Marullo R, Calvo Vidal M, et al. THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors. Nat Commun. 2017;8:14290 pubmed publisher
  3. Lacombe B, Morel M, Margottin Goguet F, Ramirez B. Specific Inhibition of HIV Infection by the Action of Spironolactone in T Cells. J Virol. 2016;90:10972-10980 pubmed publisher
  4. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  5. Chipumuro E, Marco E, Christensen C, Kwiatkowski N, Zhang T, Hatheway C, et al. CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer. Cell. 2014;159:1126-1139 pubmed publisher
  6. Kelso T, Baumgart K, Eickhoff J, Albert T, Antrecht C, Lemcke S, et al. Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells. Mol Cell Biol. 2014;34:3675-88 pubmed publisher
  7. Kainulainen M, Habjan M, Hubel P, Busch L, Lau S, Colinge J, et al. Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH. J Virol. 2014;88:3464-73 pubmed publisher