This is a Validated Antibody Database (VAD) review about rat Cdk4, based on 52 published articles (read how Labome selects the articles), using Cdk4 antibody in all methods. It is aimed to help Labome visitors find the most suited Cdk4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cdk4 synonym: cyclin-dependent kinase 4; PSK-J3; cell division protein kinase 4
Invitrogen
mouse monoclonal (DCS-31) |
| In order to determine the concordance between two methods to detect cases of atypical lipomatous tumor/well-differentiated liposarcoma, Invitrogen Cdk4 antibody (Invitrogen, AHZ0202) was used in immunohistochemistry - paraffin section on human samples (tbl 1). Am J Surg Pathol (2016) ncbi |
mouse monoclonal (DCS-31) |
| In order to study the correlation between glutamate-induced neurotoxicity and expression of cell cycle proteins in cortical neurons, Invitrogen Cdk4 antibody (Invitrogen, AHZ0202) was used in western blot on rat samples at 1:1000 (fig 4). Biofactors (2016) ncbi |
mouse monoclonal (DCS-35) |
| In order to study prostate cancer DU145 cells and anti-tumor activity of the TRPM8 inhibitor BCTC, Invitrogen Cdk4 antibody (Neomarkers, MS-299-P0) was used in western blot on human samples at 1:1000 (fig 2). Oncol Lett (2016) ncbi |
mouse monoclonal (DCS-31) |
| In order to identify mutations in desmoplastic melanoma samples, Invitrogen Cdk4 antibody (Invitrogen, AHZ0202) was used in immunohistochemistry on human samples (fig s4). Nat Genet (2015) ncbi |
mouse monoclonal (DCS-31) |
| In order to analyze sensitivity to the cyclin D1/CDK4 pathway inhibition in Ewing sarcoma by a chemical genomic, functional, and super-enhancer screening, Invitrogen Cdk4 antibody (Thermo Fisher Scientific, MS-469-P0) was used in western blot on human samples (fig 5). Oncotarget (2015) ncbi |
mouse monoclonal (DCS-31) |
| In order to investigate the frequency and contribution of HMGA2, CDK4, and JUN to dedifferentiated liposarcomas and atypical lipomatous tumors/well-differentiated liposarcomas, Invitrogen Cdk4 antibody (Biosource International, DCS 31) was used in immunohistochemistry on human samples . Mod Pathol (2015) ncbi |
mouse monoclonal (DCS-31) |
| In order to characterize a primary myxoid liposarcoma with chondroid and osseous components, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:50. Appl Immunohistochem Mol Morphol (2015) ncbi |
mouse monoclonal (DCS-31) |
| Invitrogen Cdk4 antibody (Invitrogen, clone DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:200. Hum Pathol (2015) ncbi |
mouse monoclonal (DCS-31) |
| In order to determine the role and diagnostic efficacy of RB1, CDK4, CHMP2B, HSP90, and cPLA2G4A as markers in myxofibrosarcomas and myxoid liposarcomas, Invitrogen Cdk4 antibody (Life Technologies, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:100. Int J Surg Pathol (2014) ncbi |
mouse monoclonal (DCS-31) |
| In order to describe a woman showing an incidental hibernoma associated with a cortical adenoma producing primary hyperaldosteronism, Invitrogen Cdk4 antibody (Biosource International, DCS-31) was used in immunohistochemistry on human samples . Pathol Res Pract (2013) ncbi |
mouse monoclonal (DCS-31) |
| In order to report on a case of plexiform fibromyxoma of the stomach, Invitrogen Cdk4 antibody (Invitrogen, DCS-31) was used in immunohistochemistry on human samples at 1:700 (tbl 1). Int J Surg Pathol (2014) ncbi |
mouse monoclonal (DCS-31) |
| Invitrogen Cdk4 antibody (Invitrogen, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:200. World Neurosurg (2014) ncbi |
mouse monoclonal (DCS-31) |
| In order to study the clinicopathological and genetic features of well-differentiated/dedifferentiated liposarcoma with prominent myxoid stroma, Invitrogen Cdk4 antibody (Invitrogen, DCS-31) was used in immunohistochemistry on human samples at 1:250 (fig 4). Histopathology (2013) ncbi |
mouse monoclonal (DCS-31) |
| In order to assess if MDM2 copy number distinguishes lipomas from atypical lipomatous tumors, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry on human samples (fig 3). Mod Pathol (2012) ncbi |
mouse monoclonal (DCS-31) |
| In order to discuss markers that distinguish between different subtypes of osteosarcomas, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 1.). Am J Surg Pathol (2012) ncbi |
mouse monoclonal (DCS-31) |
| In order to characterize malignant fat-forming solitary fibrous tumor, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunocytochemistry on human samples at 1:250 (fig 8). Am J Surg Pathol (2011) ncbi |
mouse monoclonal (DCS-31) |
| In order to examine expression of MDM2-CDK4 in low-grade osteosarcomas and fibrous or fibro-osseous lesions of the bone or paraosseous soft tissue, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry on human samples at 1:50 (fig 6). Mod Pathol (2011) ncbi |
mouse monoclonal (DCS-31) |
| In order to use 9 cases of well-differentiated/dedifferentiated liposarcoma to characterize unappreciated features, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 2). Am J Surg Pathol (2010) ncbi |
mouse monoclonal (DCS-31) |
| In order to explore the use of MDM2 and CDK4 for the histological diagnosis of low-grade osteosarcoma, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 3). Mod Pathol (2010) ncbi |
mouse monoclonal (DCS-31) |
| In order to characterize 12 unusual liposarcomas, Invitrogen Cdk4 antibody (Biosource/Invitrogen, clone DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:250 (fig 6). Am J Surg Pathol (2010) ncbi |
mouse monoclonal (DCS-31) |
| In order to study the significance of CDK4 amplification in well-differentiated and dedifferentiated liposarcomas, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry on human samples (fig 3). Clin Cancer Res (2009) ncbi |
mouse monoclonal (DCS-31) |
| In order to report genetic changes in dedifferentiated liposarcomas, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:100. Mod Pathol (2009) ncbi |
mouse monoclonal (DCS-31) |
| In order to discuss a rare presentation of a lipoleiomyosarcoma and review the method of pathologic diagnosis, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry on human samples (fig 2). Am J Clin Oncol (2009) ncbi |
mouse monoclonal (DCS-31) |
| In order to discuss the properties of desmoid tumors, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry on human samples (tbl 2). JOP (2008) ncbi |
mouse monoclonal (DCS-31) |
| In order to assess if immunostaining for PPAR-gamma distinguishes dedifferentiated liposarcoma from other retroperitoneal sarcomas, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:100. Mod Pathol (2008) ncbi |
mouse monoclonal (DCS-35) |
| In order to study if the growth state-dependent tyrosine phosphorylation of p27Kip1 determines whether or not it inhibits cdk4, Invitrogen Cdk4 antibody (NeoMarkers, DCS-35) was used in immunoprecipitation on American mink samples , in western blot on American mink samples and in immunoprecipitation on scFv samples . Mol Cell Biol (2008) ncbi |
mouse monoclonal (DCS-31) |
| In order to elucidate how treatment with gallotannin prevents cancer, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in western blot on human samples . Mol Carcinog (2007) ncbi |
mouse monoclonal (DCS-31) |
| In order to present a unique case of relapsing retroperitoneal dedifferentiated liposarcoma with alpha-fetoprotein ectopic production, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 1). Virchows Arch (2006) ncbi |
mouse monoclonal (DCS-31) |
| In order to present the case of a patient with a rare atypical lipomatous tumor with spindle cell features, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples at 1:400 (tbl 1). Virchows Arch (2005) ncbi |
mouse monoclonal (DCS-31) |
| In order to characterize dedifferentiated liposarcomas with an inflammatory malignant fibrous histiocytoma component, Invitrogen Cdk4 antibody (Biosource International, clone DCS-31) was used in immunohistochemistry - frozen section on human samples at 1:200 (fig 3). J Pathol (2004) ncbi |
mouse monoclonal (DCS-31) |
| In order to report that cicaprost regulates the expression of Skp2, Invitrogen Cdk4 antibody (BioSource, DCS-31) was used in western blot on mouse samples (fig 2). J Biol Chem (2004) ncbi |
mouse monoclonal (DCS-31) |
| In order to report that most so-called malignant fibrous histiocytomas from the retroperitoneum are dedifferentiated liposarcoma, Invitrogen Cdk4 antibody (Biosource, DCS-31) was used in immunohistochemistry - paraffin section on human samples . Mod Pathol (2003) ncbi |
Santa Cruz Biotechnology
mouse monoclonal (DCS-31) |
| Santa Cruz Biotechnology Cdk4 antibody (SantaCruz, sc-56277) was used in western blot on human samples (fig 2b). Mol Cell (2017) ncbi |
mouse monoclonal (97) |
| Santa Cruz Biotechnology Cdk4 antibody (SantaCruz, sc-136241) was used in western blot on human samples (fig 5c). Oncogene (2017) ncbi |
mouse monoclonal (3F121) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz, sc-70831) was used in immunoprecipitation on human samples at 1:50 (fig 5f) and in western blot on human samples (fig 5f). Nat Commun (2017) ncbi |
mouse monoclonal (DCS-35) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz Biotechnology, sc-23896) was used in western blot on human samples at 1:200 (fig 5a). Oncotarget (2017) ncbi |
mouse monoclonal (DCS-35) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz, sc-23896) was used in western blot on human samples at 1:500 (fig 5h). Nat Commun (2017) ncbi |
mouse monoclonal (3F121) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz, sc-70831) was used in western blot on human samples (fig 2). BMC Cancer (2016) ncbi |
mouse monoclonal (DCS-31) |
| In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Cdk4 antibody (SCBT, DCS-31) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi |
mouse monoclonal (DCS-35) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz, SC23896) was used in western blot on human samples at 1:1000 (fig 1). Mol Med Rep (2015) ncbi |
mouse monoclonal (DCS-35) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz, SC23896) was used in western blot on rat samples at 1:500 (fig 3). Int J Mol Med (2015) ncbi |
mouse monoclonal (DCS-31) |
| In order to analyze the anti-cancer effect of fucoidan on human colon cancer cells, Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz Biotechnology, sc-56277) was used in western blot on human samples at 1:1000 (fig 1). Mol Med Rep (2015) ncbi |
mouse monoclonal (DCS-35) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz, SC23896) was used in western blot on human samples (fig 7). PLoS ONE (2015) ncbi |
mouse monoclonal (DCS-35) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz Biotechnology, sc-23896) was used in western blot on human samples (fig 3). Cell Cycle (2015) ncbi |
mouse monoclonal (DCS-35) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz Biotechnology, sc-23896) was used in western blot on human samples . BMC Cancer (2014) ncbi |
mouse monoclonal (B-10) |
| Santa Cruz Biotechnology Cdk4 antibody (Santa Cruz, sc-166373) was used in western blot on human samples . Exp Cell Res (2014) ncbi |
Abcam
rabbit monoclonal (EPR17525) |
| Abcam Cdk4 antibody (Abcam, ab199728) was used in western blot on rat samples at 1:2000 (fig 6c). Biosci Rep (2018) ncbi |
Proteintech Group
rabbit polyclonal |
| Proteintech Group Cdk4 antibody (Proteintech, 11026) was used in western blot on human samples (fig 2c). Tumour Biol (2016) ncbi |
rabbit polyclonal |
| Proteintech Group Cdk4 antibody (Proteintech, 11026-1-AP) was used in western blot on human samples at 1:1000 (fig 5). Oncotarget (2015) ncbi |
Novus Biologicals
rabbit polyclonal |
| In order to elucidate how feline panleukopenia virus maintains host cells in the S phase, Novus Biologicals Cdk4 antibody (Novus Biologicals, NBP1-31308) was used in immunohistochemistry - paraffin section on cat samples at 1:100 (fig 5e), in western blot on cat samples at 1:100 (fig 4b) and in western blot on human samples at 1:100 (fig 4a). Cell Cycle (2016) ncbi |
GeneTex
mouse monoclonal (DCS-31.2) |
| GeneTex Cdk4 antibody (GeneTex, GTX75694) was used in immunohistochemistry on human samples at 1:50. Pathol Res Pract (2014) ncbi |
Sigma-Aldrich
mouse monoclonal (DCS-31) |
| In order to determine the effect of the hepatitis C viral load on host DNA damage, Sigma-Aldrich Cdk4 antibody (Sigma, C8218) was used in western blot on human samples (fig 1b). PLoS ONE (2017) ncbi |
Articles Reviewed
- Hrgovic I, Doll M, Kleemann J, Wang X, Zoeller N, Pinter A, et al. The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. BMC Cancer. 2016;16:763 pubmed
- Clay M, Martinez A, Weiss S, Edgar M. MDM2 and CDK4 Immunohistochemistry: Should It Be Used in Problematic Differentiated Lipomatous Tumors?: A New Perspective. Am J Surg Pathol. 2016;40:1647-1652 pubmed
- Zhao Y, Zhang B, Lei Y, Sun J, Zhang Y, Yang S, et al. Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma. Tumour Biol. 2016;37:13167-13176 pubmed
- Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016;11:182-188 pubmed
- Meng D, Chen Y, Yun D, Zhao Y, Wang J, Xu T, et al. High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma. Oncotarget. 2015;6:4901-19 pubmed
- Mariño Enríquez A, Fletcher C, Dal Cin P, Hornick J. Dedifferentiated liposarcoma with "homologous" lipoblastic (pleomorphic liposarcoma-like) differentiation: clinicopathologic and molecular analysis of a series suggesting revised diagnostic criteria. Am J Surg Pathol. 2010;34:1122-31 pubmed publisher
- Amiot A, Dokmak S, Sauvanet A, Vilgrain V, Bringuier P, Scoazec J, et al. Sporadic desmoid tumor. An exceptional cause of cystic pancreatic lesion. JOP. 2008;9:339-45 pubmed
- James M, Ray A, Leznova D, Blain S. Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity. Mol Cell Biol. 2008;28:498-510 pubmed
- Al Ayyoubi S, Gali Muhtasib H. Differential apoptosis by gallotannin in human colon cancer cells with distinct p53 status. Mol Carcinog. 2007;46:176-86 pubmed
- Bosco M, Allia E, Coindre J, Odasso C, Pagani A, Pacchioni D. alpha-fetoprotein expression in a dedifferentiated liposarcoma. Virchows Arch. 2006;448:517-20 pubmed
- Mentzel T, Toennissen J, Rutten A, Schaller J. Palmar atypical lipomatous tumour with spindle cell features (well-differentiated spindle cell liposarcoma): a rare neoplasm arising in an unusual anatomical location. Virchows Arch. 2005;446:300-4 pubmed
- Coindre J, Hostein I, Maire G, Derré J, Guillou L, Leroux A, et al. Inflammatory malignant fibrous histiocytomas and dedifferentiated liposarcomas: histological review, genomic profile, and MDM2 and CDK4 status favour a single entity. J Pathol. 2004;203:822-30 pubmed
- Stewart S, Kothapalli D, Yung Y, Assoian R. Antimitogenesis linked to regulation of Skp2 gene expression. J Biol Chem. 2004;279:29109-13 pubmed
- Coindre J, Mariani O, Chibon F, Mairal A, De Saint Aubain Somerhausen N, Favre Guillevin E, et al. Most malignant fibrous histiocytomas developed in the retroperitoneum are dedifferentiated liposarcomas: a review of 25 cases initially diagnosed as malignant fibrous histiocytoma. Mod Pathol. 2003;16:256-62 pubmed
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