This is a Validated Antibody Database (VAD) review about rat Cdk2, based on 98 published articles (read how Labome selects the articles), using Cdk2 antibody in all methods. It is aimed to help Labome visitors find the most suited Cdk2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (D-12)
  • western blot knockout validation; mouse; loading ...; fig 3c
  • western blot; human; loading ...; fig 5b
In order to look for potential tumor suppressors and examine their function as cell cycle modulators and investigate their impact on the cyclin family of proteins and cyclin dependent kinases, Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, 6248) was used in western blot knockout validation on mouse samples (fig 3c) and in western blot on human samples (fig 5b). Mol Pharmacol (2017) ncbi
Abcam
domestic rabbit monoclonal (E304)
  • western blot knockout validation; human; loading ...; fig 5f
Abcam Cdk2 antibody (Abcam, ab32147) was used in western blot knockout validation on human samples (fig 5f). Nucleic Acids Res (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-12)
  • immunocytochemistry; rat; 1:200; fig 7g
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in immunocytochemistry on rat samples at 1:200 (fig 7g). BMC Biol (2021) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; 1:200; loading ...; fig 7a
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz Biotechnology, sc-6248) was used in western blot on mouse samples at 1:200 (fig 7a). PLoS Genet (2020) ncbi
mouse monoclonal (D-12)
  • immunohistochemistry; mouse; 1:20; loading ...; fig 6c
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in immunohistochemistry on mouse samples at 1:20 (fig 6c). elife (2020) ncbi
mouse monoclonal (D-12)
  • western blot; rat; 1:200; loading ...; fig 5b
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz Biotechnology, sc-6248) was used in western blot on rat samples at 1:200 (fig 5b). Int J Nanomedicine (2020) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; 1:1000; fig 3l
Santa Cruz Biotechnology Cdk2 antibody (Santa, sc-6248) was used in western blot on mouse samples at 1:1000 (fig 3l). elife (2018) ncbi
mouse monoclonal (D-12)
  • western blot; human; 1:200; loading ...; fig 2
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz Biotechnology, sc-6248) was used in western blot on human samples at 1:200 (fig 2). Mol Med Rep (2017) ncbi
mouse monoclonal (D-12)
  • western blot; human; 1:300; loading ...; fig 1b
Santa Cruz Biotechnology Cdk2 antibody (Santa cruz, sc-6248) was used in western blot on human samples at 1:300 (fig 1b). Gene (2017) ncbi
mouse monoclonal (AN21.2)
  • western blot; mouse; fig s3
In order to explore the role of Fancd2 in normal development and tumorigenesis, Santa Cruz Biotechnology Cdk2 antibody (santa cruz, sc-53219) was used in western blot on mouse samples (fig s3). Sci Rep (2017) ncbi
mouse monoclonal (D-12)
  • immunocytochemistry; human; 1:200; loading ...; fig s6e
  • western blot; human; 1:500; loading ...; fig s6g
In order to show that USP9X regulates centrosome biogenesis and plays a role breast carcinogenesis, Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in immunocytochemistry on human samples at 1:200 (fig s6e) and in western blot on human samples at 1:500 (fig s6g). Nat Commun (2017) ncbi
mouse monoclonal (AN21.2)
  • western blot; human; 1:200; loading ...; fig 5a
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz Biotechnology, sc-53219) was used in western blot on human samples at 1:200 (fig 5a). Oncotarget (2017) ncbi
mouse monoclonal (D-12)
  • immunocytochemistry; mouse; 1:50; loading ...; fig s5d
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz Biotechnology Inc, sc-6248) was used in immunocytochemistry on mouse samples at 1:50 (fig s5d). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (D-12)
  • immunoprecipitation; mouse; loading ...; fig s13d
  • immunocytochemistry; mouse; loading ...; fig s7
  • immunohistochemistry; mouse; loading ...; fig 3f
  • western blot; mouse; loading ...; fig s13e
  • immunohistochemistry; human; loading ...; fig s12
  • western blot; human; loading ...; fig 3d
  • immunocytochemistry; rat; loading ...; fig s7
In order to search for signaling pathways that modulate polyglutamine-androgen receptor phosphorylation for therapy development, Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in immunoprecipitation on mouse samples (fig s13d), in immunocytochemistry on mouse samples (fig s7), in immunohistochemistry on mouse samples (fig 3f), in western blot on mouse samples (fig s13e), in immunohistochemistry on human samples (fig s12), in western blot on human samples (fig 3d) and in immunocytochemistry on rat samples (fig s7). Sci Transl Med (2016) ncbi
mouse monoclonal (D-12)
  • western blot knockout validation; mouse; loading ...; fig 3c
  • western blot; human; loading ...; fig 5b
In order to look for potential tumor suppressors and examine their function as cell cycle modulators and investigate their impact on the cyclin family of proteins and cyclin dependent kinases, Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, 6248) was used in western blot knockout validation on mouse samples (fig 3c) and in western blot on human samples (fig 5b). Mol Pharmacol (2017) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; loading ...; fig 6c
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on mouse samples (fig 6c). Nat Commun (2016) ncbi
mouse monoclonal (D-12)
  • immunoprecipitation; mouse; 1:1000; loading ...; fig s3c
  • western blot; mouse; 1:1000; loading ...; fig s3c
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc6248) was used in immunoprecipitation on mouse samples at 1:1000 (fig s3c) and in western blot on mouse samples at 1:1000 (fig s3c). Science (2016) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; fig s3
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, SC-6248) was used in western blot on mouse samples (fig s3). PLoS Genet (2016) ncbi
mouse monoclonal (D-12)
  • western blot; human; 1:500; fig 1
Santa Cruz Biotechnology Cdk2 antibody (santa Cruz, sc6248) was used in western blot on human samples at 1:500 (fig 1). Oncol Lett (2016) ncbi
mouse monoclonal (D-12)
  • immunoprecipitation; human; fig 4
Santa Cruz Biotechnology Cdk2 antibody ((Santa Cruz, D12) was used in immunoprecipitation on human samples (fig 4). Cell Rep (2015) ncbi
mouse monoclonal (D-12)
  • western blot; human; fig 3
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on human samples (fig 3). BMC Cancer (2015) ncbi
mouse monoclonal (D-12)
  • western blot; human; fig 6
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on human samples (fig 6). Mol Med Rep (2015) ncbi
mouse monoclonal (AN21.2)
  • western blot; human; fig 4
Santa Cruz Biotechnology Cdk2 antibody (santa Cruz, sc-53219) was used in western blot on human samples (fig 4). PLoS ONE (2015) ncbi
mouse monoclonal (D-12)
  • chromatin immunoprecipitation; mouse; fig 6
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in chromatin immunoprecipitation on mouse samples (fig 6). Nucleic Acids Res (2015) ncbi
mouse monoclonal (D-12)
  • western blot; human; fig 7
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, SC6248) was used in western blot on human samples (fig 7). PLoS ONE (2015) ncbi
mouse monoclonal (D-12)
  • western blot; human; 1:200; fig 3b
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz Biotechnology, sc-6248) was used in western blot on human samples at 1:200 (fig 3b). Int J Oncol (2015) ncbi
mouse monoclonal (D-12)
  • western blot; human; fig 3
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz Biotechnology, sc-6248) was used in western blot on human samples (fig 3). Cell Cycle (2015) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; 1:1000; fig 5
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2015) ncbi
mouse monoclonal (AN21.2)
  • western blot; human; fig s2f
In order to study the effects of cyclin-dependent kinase 7 inhibitors on MYC proteins, Santa Cruz Biotechnology Cdk2 antibody (Santa, sc-53219) was used in western blot on human samples (fig s2f). Cell (2014) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; 1:400
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on mouse samples at 1:400. Cell Physiol Biochem (2014) ncbi
mouse monoclonal (D-12)
  • western blot; human; 1:500-1:1000
In order to study the effect of imatinib on neuroblastoma cell lines, Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on human samples at 1:500-1:1000. Biochem Pharmacol (2014) ncbi
mouse monoclonal (D-12)
  • western blot; human; loading ...; fig 5a
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on human samples (fig 5a). PLoS ONE (2014) ncbi
mouse monoclonal (D-12)
  • western blot; human
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on human samples . Exp Cell Res (2014) ncbi
mouse monoclonal (D-12)
  • western blot; human; 1:200
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz Biotechnology, sc-6248) was used in western blot on human samples at 1:200. Tumour Biol (2014) ncbi
mouse monoclonal (D-12)
  • western blot; human
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on human samples . Cell Cycle (2013) ncbi
mouse monoclonal (D-12)
  • western blot; mouse; fig 4
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on mouse samples (fig 4). Proc Natl Acad Sci U S A (2012) ncbi
mouse monoclonal (D-12)
  • western blot; human; fig 3
Santa Cruz Biotechnology Cdk2 antibody (Santa Cruz, sc-6248) was used in western blot on human samples (fig 3). Clin Cancer Res (2010) ncbi
Abcam
domestic rabbit monoclonal (E304)
  • immunohistochemistry; mouse; loading ...; fig 4
  • western blot; human; fig 6c
Abcam Cdk2 antibody (Abcam, E304) was used in immunohistochemistry on mouse samples (fig 4) and in western blot on human samples (fig 6c). Int J Mol Sci (2021) ncbi
domestic rabbit monoclonal (E304)
  • immunohistochemistry; mouse; loading ...; fig 8b
Abcam Cdk2 antibody (Abcam, ab32147) was used in immunohistochemistry on mouse samples (fig 8b). J Hepatocell Carcinoma (2021) ncbi
domestic rabbit monoclonal (E304)
  • western blot; human; 1:1000; loading ...; fig s2d
Abcam Cdk2 antibody (Abcam, ab32147) was used in western blot on human samples at 1:1000 (fig s2d). BMC Cancer (2020) ncbi
domestic rabbit monoclonal (E304)
  • immunohistochemistry - paraffin section; human; loading ...; fig 7d
  • western blot; human; 1:2000; loading ...; fig 4e
Abcam Cdk2 antibody (Abcam, ab32147) was used in immunohistochemistry - paraffin section on human samples (fig 7d) and in western blot on human samples at 1:2000 (fig 4e). Aging (Albany NY) (2020) ncbi
domestic rabbit monoclonal (E304)
  • western blot; human; loading ...; fig 2j
Abcam Cdk2 antibody (Abcam, ab32147) was used in western blot on human samples (fig 2j). Aging (Albany NY) (2019) ncbi
domestic rabbit monoclonal (E304)
  • western blot; rat; loading ...; fig 2d
Abcam Cdk2 antibody (Abcam, ab32147) was used in western blot on rat samples (fig 2d). Biosci Rep (2019) ncbi
domestic rabbit monoclonal (E304)
  • western blot; rat; 1:2000; loading ...; fig 6c
Abcam Cdk2 antibody (Abcam, ab32147) was used in western blot on rat samples at 1:2000 (fig 6c). Biosci Rep (2018) ncbi
domestic rabbit monoclonal (E161)
  • other; human; loading ...; fig 4c
Abcam Cdk2 antibody (Abcam, ab32384) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (E304)
  • western blot; human; loading ...; fig 4a
Abcam Cdk2 antibody (Abcam, ab32147) was used in western blot on human samples (fig 4a). Oncogene (2018) ncbi
domestic rabbit monoclonal (E304)
  • western blot knockout validation; human; loading ...; fig 5f
Abcam Cdk2 antibody (Abcam, ab32147) was used in western blot knockout validation on human samples (fig 5f). Nucleic Acids Res (2018) ncbi
domestic rabbit monoclonal (E161)
  • western blot; mouse; 1:1000; loading ...; fig 4b
Abcam Cdk2 antibody (Abcam, ab32384) was used in western blot on mouse samples at 1:1000 (fig 4b). Redox Biol (2017) ncbi
domestic rabbit monoclonal (EPR2233Y)
  • western blot; human; 1:500; loading ...; fig 3d
Abcam Cdk2 antibody (Abcam, ab76146) was used in western blot on human samples at 1:500 (fig 3d). Nat Commun (2016) ncbi
domestic rabbit monoclonal (E161)
  • western blot; human; fig 5
In order to characterize modulation of microtubular structure and HSP90alpha chaperone activity against prostate cancer by 4-hydroxybenzoic acid derivatives as HDAC6-specific inhibitors, Abcam Cdk2 antibody (Abcam, ab32384) was used in western blot on human samples (fig 5). Biochem Pharmacol (2016) ncbi
domestic rabbit monoclonal (E161)
  • western blot; mouse; fig s4
Abcam Cdk2 antibody (Abcam, ab32384) was used in western blot on mouse samples (fig s4). Cell Death Differ (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on human samples at 1:1000 (fig 3b). Clin Transl Med (2021) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on human samples (fig 4a). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; axolotl; 1:1000; loading ...; fig 3s2b
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546S) was used in western blot on axolotl samples at 1:1000 (fig 3s2b). elife (2020) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 4g
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 78B2) was used in western blot on human samples (fig 4g). Sci Rep (2020) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 4g
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on human samples (fig 4g). Mol Oncol (2020) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on human samples (fig 1a). Breast Cancer Res (2019) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; loading ...; fig 6a
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546S) was used in western blot on human samples at 1:1000 (fig 6a). Science (2019) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; loading ...; fig 5a
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 78B2) was used in western blot on human samples at 1:1000 (fig 5a). Nat Commun (2019) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; loading ...; fig 2g
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546S) was used in western blot on human samples at 1:1000 (fig 2g). Cell Death Dis (2019) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546S) was used in western blot on human samples (fig 7a). Mol Cell (2019) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; mouse; loading ...; fig 4d
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on mouse samples (fig 4d). Cell Rep (2019) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; loading ...; fig 2d
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on human samples at 1:1000 (fig 2d). J Exp Clin Cancer Res (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2d
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2561) was used in western blot on human samples at 1:1000 (fig 2d). J Exp Clin Cancer Res (2019) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; mouse; loading ...; fig s4b
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on mouse samples (fig s4b). Gastroenterology (2018) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 1c
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546P) was used in western blot on human samples (fig 1c). Mol Cell (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; 1:100; loading ...; fig 5c
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2561S) was used in immunocytochemistry on mouse samples at 1:100 (fig 5c). Biol Reprod (2018) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; mouse; 1:1000; loading ...; fig s7g
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on mouse samples at 1:1000 (fig s7g). Cancer Discov (2017) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 3e
Cell Signaling Technology Cdk2 antibody (Cell signaling, 2546) was used in western blot on human samples (fig 3e). Leuk Lymphoma (2018) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:500; loading ...; fig 3a
In order to elucidate the mechanism of Pin1 overexpression in hepatocellular carcinoma, Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546 S) was used in western blot on human samples at 1:500 (fig 3a). Sci Rep (2017) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; loading ...; fig 4c
Cell Signaling Technology Cdk2 antibody (cell signalling, 2546) was used in western blot on human samples at 1:1000 (fig 4c). Int J Oncol (2017) ncbi
domestic rabbit monoclonal (78B2)
  • immunohistochemistry - frozen section; mouse; 1:700; loading ...; fig 11g
  • western blot; mouse; 1:700
Cell Signaling Technology Cdk2 antibody (Cell Signaling, mAB2546) was used in immunohistochemistry - frozen section on mouse samples at 1:700 (fig 11g) and in western blot on mouse samples at 1:700. J Neurosci (2017) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 6
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on human samples (fig 6). Drug Des Devel Ther (2016) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 5a
In order to report the effects of NVP-CGM097 on the p53wildtype GOT1 cells, Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on human samples (fig 5a). Neuroendocrinology (2018) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; fig 2i
Cell Signaling Technology Cdk2 antibody (Cell signaling, 2546) was used in western blot on human samples (fig 2i). Nat Med (2017) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:5000; loading ...; fig 1b
In order to demonstrate the bipartite role of Hsp90 in chaperoning CRAF kinase, Cell Signaling Technology Cdk2 antibody (Cell Signaling, 78B2) was used in western blot on human samples at 1:5000 (fig 1b). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; fig 5
Cell Signaling Technology Cdk2 antibody (Cell Signaling Tech, 2546) was used in western blot on human samples (fig 5). Sci Rep (2016) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:2000; loading ...; fig 5c
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on human samples at 1:2000 (fig 5c). Oncotarget (2016) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; loading ...; fig s3b
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on human samples at 1:1000 (fig s3b). Oncogene (2017) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; fig 5c
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on human samples at 1:1000 (fig 5c). Cancer Chemother Pharmacol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1c
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2561) was used in western blot on mouse samples (fig 1c). Oncotarget (2016) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; mouse; loading ...; fig 1c
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on mouse samples (fig 1c). Oncotarget (2016) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:1000; loading ...; fig 3e
Cell Signaling Technology Cdk2 antibody (CST, 2546) was used in western blot on human samples at 1:1000 (fig 3e). Aging (Albany NY) (2016) ncbi
domestic rabbit monoclonal (78B2)
  • immunohistochemistry - paraffin section; human; 1:100; fig s1
In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig s1). BMC Cancer (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1500; fig s1
In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2561) was used in immunohistochemistry - paraffin section on human samples at 1:1500 (fig s1). BMC Cancer (2016) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; fig 4
Cell Signaling Technology Cdk2 antibody (Cell signaling, 2546P) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit monoclonal (78B2)
  • immunoprecipitation; human; 1:1000; fig 2
  • western blot; human; 1:1000; fig 2
In order to investigate factors that control PHD1 activity, Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in immunoprecipitation on human samples at 1:1000 (fig 2) and in western blot on human samples at 1:1000 (fig 2). J Cell Sci (2016) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; mouse; 1:250; fig 2c
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on mouse samples at 1:250 (fig 2c). FEBS Open Bio (2015) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; fig 3d
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on human samples (fig 3d). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (78B2)
  • other; mouse; 1:1000; fig s1
In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in other on mouse samples at 1:1000 (fig s1). Front Microbiol (2015) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; 1:2000
In order to study the contribution of the Skp2-mH2A1-CDK8 axis to breast cancer, Cell Signaling Technology Cdk2 antibody (Cell signaling, 2546P) was used in western blot on human samples at 1:2000. Nat Commun (2015) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on human samples . Int J Oncol (2015) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; fig 1
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; fig 2d
In order to study the effects of cyclin-dependent kinase 7 inhibitors on MYC proteins, Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on human samples (fig 2d). Cell (2014) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; mouse
Cell Signaling Technology Cdk2 antibody (Cell Signaling Technology, 2546) was used in western blot on mouse samples . Biochim Biophys Acta (2015) ncbi
domestic rabbit monoclonal (78B2)
  • western blot; human; loading ...; fig 6e
Cell Signaling Technology Cdk2 antibody (Cell Signaling, 2546) was used in western blot on human samples (fig 6e). Mol Endocrinol (2014) ncbi
BD Biosciences
mouse monoclonal (55/Cdk2)
  • western blot; human; 1:200; loading ...; fig 2a
In order to describe how a CHK1 inhibitor reduces the growth of radioresistant breast cancer cells, BD Biosciences Cdk2 antibody (BD Biosciences, 610146) was used in western blot on human samples at 1:200 (fig 2a). Oncotarget (2016) ncbi
mouse monoclonal (55/Cdk2)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Cdk2 antibody (BD, 55) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (55/Cdk2)
  • western blot; human; fig 2c
BD Biosciences Cdk2 antibody (BD Pharmingen, 610145) was used in western blot on human samples (fig 2c). Onco Targets Ther (2015) ncbi
mouse monoclonal (55/Cdk2)
  • western blot; human; 1:250; fig 5
BD Biosciences Cdk2 antibody (BD Biosciences, 610145) was used in western blot on human samples at 1:250 (fig 5). Front Microbiol (2015) ncbi
mouse monoclonal (55/Cdk2)
  • western blot; human
  • western blot; chicken
BD Biosciences Cdk2 antibody (BD, 55) was used in western blot on human samples and in western blot on chicken samples . PLoS Pathog (2014) ncbi
mouse monoclonal (55/Cdk2)
  • immunohistochemistry; African green monkey; 1:100
BD Biosciences Cdk2 antibody (BD Biosciences, 610145) was used in immunohistochemistry on African green monkey samples at 1:100. Endocrinology (2014) ncbi
mouse monoclonal (55/Cdk2)
  • immunocytochemistry; human
In order to identify the role of PCTAIRE1 in cancer cells, BD Biosciences Cdk2 antibody (BD, 610145) was used in immunocytochemistry on human samples . Cancer Res (2014) ncbi
mouse monoclonal (55/Cdk2)
  • western blot; human; 1:400; fig 2
In order to develop a neuregulin-1 overexpressing transgenic mouse model of neurofibroma-malignant peripheral nerve sheath tumor progression, BD Biosciences Cdk2 antibody (BD Biosciences, 610145) was used in western blot on human samples at 1:400 (fig 2). Am J Pathol (2013) ncbi
Articles Reviewed
  1. Sakai H, Kawakami H, Teramura T, Onodera Y, Somers E, Furuuchi K, et al. Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer. Clin Transl Med. 2021;11:e454 pubmed publisher
  2. Schwiebs A, Faqar Uz Zaman F, Herrero San Juan M, Radeke H. S1P Lyase Regulates Intestinal Stem Cell Quiescence via Ki-67 and FOXO3. Int J Mol Sci. 2021;22: pubmed publisher
  3. Zhang Y, Zhang H, Wu S. LncRNA-CCDC144NL-AS1 Promotes the Development of Hepatocellular Carcinoma by Inducing WDR5 Expression via Sponging miR-940. J Hepatocell Carcinoma. 2021;8:333-348 pubmed publisher
  4. Mihola O, Landa V, Pratto F, Brick K, Kobets T, Kusari F, et al. Rat PRDM9 shapes recombination landscapes, duration of meiosis, gametogenesis, and age of fertility. BMC Biol. 2021;19:86 pubmed publisher
  5. Dong C, Jiang T, Yin H, Song H, Zhang Y, Geng H, et al. LMNB2 promotes the progression of colorectal cancer by silencing p21 expression. Cell Death Dis. 2021;12:331 pubmed publisher
  6. Dewhurst M, Ow J, Zafer G, Van Hul N, Wollmann H, Bisteau X, et al. Loss of hepatocyte cell division leads to liver inflammation and fibrosis. PLoS Genet. 2020;16:e1009084 pubmed publisher
  7. Felipe Medina N, Caburet S, Sánchez Sáez F, Condezo Y, de Rooij D, Gómez H L, et al. A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1. elife. 2020;9: pubmed publisher
  8. Chen J, Liu X, Ke K, Zou J, Gao Z, Habuchi T, et al. LINC00992 contributes to the oncogenic phenotypes in prostate cancer via targeting miR-3935 and augmenting GOLM1 expression. BMC Cancer. 2020;20:749 pubmed publisher
  9. Sousounis K, Bryant D, Martínez Fernández J, Eddy S, Tsai S, Gundberg G, et al. Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration. elife. 2020;9: pubmed publisher
  10. Lin Y, Huang X, Chang K, Liao K, Tsai N. Encapsulated n-Butylidenephthalide Efficiently Crosses the Blood-Brain Barrier and Suppresses Growth of Glioblastoma. Int J Nanomedicine. 2020;15:749-760 pubmed publisher
  11. Huang S, Zhang C, Sun C, Hou Y, Zhang Y, Tam N, et al. Obg-like ATPase 1 (OLA1) overexpression predicts poor prognosis and promotes tumor progression by regulating P21/CDK2 in hepatocellular carcinoma. Aging (Albany NY). 2020;12:3025-3041 pubmed publisher
  12. Showalter A, Martini A, Nierenberg D, Hosang K, Fahmi N, Gopalan P, et al. Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis. Sci Rep. 2020;10:798 pubmed publisher
  13. Wang H, Chen Z, Wang S, Gao X, Qian M, Qiu W, et al. TGFβ1-induced beta-site APP-cleaving enzyme 2 upregulation promotes tumorigenesis through the NF-κB signalling pathway in human gliomas. Mol Oncol. 2020;14:407-425 pubmed publisher
  14. Patel H, Tao N, Lee K, Huerta M, Arlt H, Mullarkey T, et al. Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors. Breast Cancer Res. 2019;21:146 pubmed publisher
  15. Guiley K, Stevenson J, Lou K, Barkovich K, Kumarasamy V, Wijeratne T, et al. p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. Science. 2019;366: pubmed publisher
  16. Ghezzi C, Wong A, Chen B, Ribalet B, Damoiseaux R, Clark P. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. Nat Commun. 2019;10:5444 pubmed publisher
  17. Tan P, Xu Y, Du Y, Wu L, Guo B, Huang S, et al. SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG. Cell Death Dis. 2019;10:794 pubmed publisher
  18. Liu J, Yao L, Zhang M, Jiang J, Yang M, Wang Y. Downregulation of LncRNA-XIST inhibited development of non-small cell lung cancer by activating miR-335/SOD2/ROS signal pathway mediated pyroptotic cell death. Aging (Albany NY). 2019;11:7830-7846 pubmed publisher
  19. Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos S, et al. MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Mol Cell. 2019;74:674-687.e11 pubmed publisher
  20. Fang G, Qi J, Huang L, Zhao X. LncRNA MRAK048635_P1 is critical for vascular smooth muscle cell function and phenotypic switching in essential hypertension. Biosci Rep. 2019;: pubmed publisher
  21. Lin K, Qiang W, Zhu M, Ding Y, Shi Q, Chen X, et al. Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. Cell Rep. 2019;26:2434-2450.e6 pubmed publisher
  22. Tuo L, Xiang J, Pan X, Hu J, Tang H, Liang L, et al. PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27Kip1 axis. J Exp Clin Cancer Res. 2019;38:50 pubmed publisher
  23. Giera S, Luo R, Ying Y, Ackerman S, Jeong S, Stoveken H, et al. Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells. elife. 2018;7: pubmed publisher
  24. Jin L, Lu J, Gao J. Silencing SUMO2 promotes protection against degradation and apoptosis of nucleus pulposus cells through p53 signaling pathway in intervertebral disc degeneration. Biosci Rep. 2018;38: pubmed publisher
  25. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  26. Shen L, Qu X, Li H, Xu C, Wei M, Wang Q, et al. NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis. Oncogene. 2018;37:1759-1774 pubmed publisher
  27. Ji X, Humenik J, Yang D, Liebhaber S. PolyC-binding proteins enhance expression of the CDK2 cell cycle regulatory protein via alternative splicing. Nucleic Acids Res. 2018;46:2030-2044 pubmed publisher
  28. He P, Yang J, Yang V, Bialkowska A. Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice. Gastroenterology. 2018;154:1494-1508.e13 pubmed publisher
  29. Liao P, Zeng S, Zhou X, Chen T, Zhou F, Cao B, et al. Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. Mol Cell. 2017;68:1134-1146.e6 pubmed publisher
  30. Hu J, Sun F, Handel M. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018;98:102-114 pubmed publisher
  31. Ren A, Fu G, Qiu Y, Cui H. Leflunomide inhibits proliferation and tumorigenesis of oral squamous cell carcinoma. Mol Med Rep. 2017;16:9125-9130 pubmed publisher
  32. Haricharan S, Punturi N, Singh P, Holloway K, Anurag M, Schmelz J, et al. Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer. Cancer Discov. 2017;7:1168-1183 pubmed publisher
  33. Shu S, Xu Y, Xie L, Ouyang Y. The role of C/EBP? phosphorylation in modulating membrane phospholipids repairing in LPS-induced human lung/bronchial epithelial cells. Gene. 2017;629:76-85 pubmed publisher
  34. Xu L, Zhang M, Li H, Guan W, Liu B, Liu F, et al. SH3BGRL as a novel prognostic biomarker is down-regulated in acute myeloid leukemia. Leuk Lymphoma. 2018;59:918-930 pubmed publisher
  35. Yan X, Zhu Z, Xu S, Yang L, Liao X, Zheng M, et al. MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways. Sci Rep. 2017;7:45915 pubmed publisher
  36. Zhang T, Du W, Wilson A, Namekawa S, Andreassen P, Meetei A, et al. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep. 2017;7:45626 pubmed publisher
  37. Li X, Song N, Liu L, Liu X, Ding X, Song X, et al. USP9X regulates centrosome duplication and promotes breast carcinogenesis. Nat Commun. 2017;8:14866 pubmed publisher
  38. Li X, Liu F, Lin B, Luo H, Liu M, Wu J, et al. miR?150 inhibits proliferation and tumorigenicity via retarding G1/S phase transition in nasopharyngeal carcinoma. Int J Oncol. 2017;: pubmed publisher
  39. Graziano A, Cardile V, Avola R, Vicario N, Parenti C, Salvatorelli L, et al. Wilms' tumor gene 1 silencing inhibits proliferation of human osteosarcoma MG-63 cell line by cell cycle arrest and apoptosis activation. Oncotarget. 2017;8:13917-13931 pubmed publisher
  40. Hussain R, Macklin W. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle. J Neurosci. 2017;37:397-412 pubmed publisher
  41. Tu Z, Bayazit M, Liu H, Zhang J, Busayavalasa K, Risal S, et al. Speedy A-Cdk2 binding mediates initial telomere-nuclear envelope attachment during meiotic prophase I independent of Cdk2 activation. Proc Natl Acad Sci U S A. 2017;114:592-597 pubmed publisher
  42. Song X, Narzt M, Nagelreiter I, Hohensinner P, Terlecki Zaniewicz L, Tschachler E, et al. Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo. Redox Biol. 2017;11:219-230 pubmed publisher
  43. Polanco M, Parodi S, Piol D, Stack C, Chivet M, Contestabile A, et al. Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy. Sci Transl Med. 2016;8:370ra181 pubmed publisher
  44. Choiniere J, Wu J, Wang L. Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins. Mol Pharmacol. 2017;91:189-196 pubmed publisher
  45. Jablonska B, Gierdalski M, Chew L, Hawley T, Catron M, Lichauco A, et al. Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nat Commun. 2016;7:13866 pubmed publisher
  46. Lv M, Li Y, Tian X, Dai S, Sun J, Jin G, et al. Lentivirus-mediated knockdown of NLK inhibits small-cell lung cancer growth and metastasis. Drug Des Devel Ther. 2016;10:3737-3746 pubmed
  47. Reuther C, Heinzle V, Nölting S, Herterich S, Hahner S, Halilovic E, et al. The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. Neuroendocrinology. 2018;106:1-19 pubmed publisher
  48. Cramer S, Saha A, Liu J, Tadi S, Tiziani S, Yan W, et al. Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth. Nat Med. 2017;23:120-127 pubmed publisher
  49. Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  50. Mitra S, Ghosh B, Gayen N, Roy J, Mandal A. Bipartite Role of Heat Shock Protein 90 (Hsp90) Keeps CRAF Kinase Poised for Activation. J Biol Chem. 2016;291:24579-24593 pubmed
  51. Zhang Y, Zhang Y, Zhong C, Xiao F. Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes. Sci Rep. 2016;6:34578 pubmed publisher
  52. Cao R, Meng Z, Liu T, Wang G, Qian G, Cao T, et al. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget. 2016;7:72941-72960 pubmed publisher
  53. Diril M, Bisteau X, Kitagawa M, Caldez M, Wee S, Gunaratne J, et al. Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint. PLoS Genet. 2016;12:e1006310 pubmed publisher
  54. Queisser A, Hagedorn S, Wang H, Schaefer T, Konantz M, Alavi S, et al. Ecotropic viral integration site 1, a novel oncogene in prostate cancer. Oncogene. 2017;36:1573-1584 pubmed publisher
  55. Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, et al. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun. 2016;7:12431 pubmed publisher
  56. Fiedor E, Gregoraszczuk E. The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines. Cancer Chemother Pharmacol. 2016;78:611-22 pubmed publisher
  57. Zhou Y, Xu H, Ding Y, Lu Q, Zou M, Song P. AMPK?1 deletion in fibroblasts promotes tumorigenesis in athymic nude mice by p52-mediated elevation of erythropoietin and CDK2. Oncotarget. 2016;7:53654-53667 pubmed publisher
  58. Bao H, Liu P, Jiang K, Zhang X, Xie L, Wang Z, et al. Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK. Oncol Lett. 2016;12:1058-1066 pubmed
  59. Zeng L, Yang X, Wen Y, Mail S, Wang M, Zhang M, et al. Overexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinoma. Aging (Albany NY). 2016;8:1236-49 pubmed publisher
  60. Zhang Y, Lai J, Du Z, Gao J, Yang S, Gorityala S, et al. Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress. Oncotarget. 2016;7:34688-702 pubmed publisher
  61. Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher
  62. Tang Y, Huang L, Lin W, Wang L, Tian Y, Shi D, et al. Butein inhibits cell proliferation and induces cell cycle arrest in acute lymphoblastic leukemia via FOXO3a/p27kip1 pathway. Oncotarget. 2016;7:18651-64 pubmed publisher
  63. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  64. Choe C, Shin Y, Kim C, Choi S, Lee J, Kim S, et al. Crosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition. Onco Targets Ther. 2015;8:3665-78 pubmed publisher
  65. Toledo C, Ding Y, Hoellerbauer P, Davis R, Basom R, Girard E, et al. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. Cell Rep. 2015;13:2425-2439 pubmed publisher
  66. Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
  67. Lohberger B, Leithner A, Stuendl N, Kaltenegger H, Kullich W, Steinecker Frohnwieser B. Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation. BMC Cancer. 2015;15:891 pubmed publisher
  68. Seidel C, Schnekenburger M, Mazumder A, Teiten M, Kirsch G, Dicato M, et al. 4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer. Biochem Pharmacol. 2016;99:31-52 pubmed publisher
  69. Tang J, Chen Y, Cui R, Li D, Xiao L, Lin P, et al. Upregulation of fractalkine contributes to the proliferative response of prostate cancer cells to hypoxia via promoting the G1/S phase transition. Mol Med Rep. 2015;12:7907-14 pubmed publisher
  70. Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed publisher
  71. Kim Y, Chen C, Bolton E. Androgen Receptor-Mediated Growth Suppression of HPr-1AR and PC3-Lenti-AR Prostate Epithelial Cells. PLoS ONE. 2015;10:e0138286 pubmed publisher
  72. Wang J, Zhang Y, Hou J, Qian X, Zhang H, Zhang Z, et al. Ube2s regulates Sox2 stability and mouse ES cell maintenance. Cell Death Differ. 2016;23:393-404 pubmed publisher
  73. Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  74. Wu C, Huang K, Yang T, Li Y, Wen C, Hsu S, et al. The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells. PLoS ONE. 2015;10:e0132052 pubmed publisher
  75. Orlando S, Gallastegui E, Besson A, Abril G, Aligué R, Pujol M, et al. p27Kip1 and p21Cip1 collaborate in the regulation of transcription by recruiting cyclin-Cdk complexes on the promoters of target genes. Nucleic Acids Res. 2015;43:6860-73 pubmed publisher
  76. Guha G, Lu W, Li S, Liang X, Kulesz Martin M, Mahmud T, et al. Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells. PLoS ONE. 2015;10:e0125322 pubmed publisher
  77. Suzuki M, Takeda T, Nakagawa H, Iwata S, Watanabe T, Siddiquey M, et al. The heat shock protein 90 inhibitor BIIB021 suppresses the growth of T and natural killer cell lymphomas. Front Microbiol. 2015;6:280 pubmed publisher
  78. Xu D, Li C, Zhang X, Gong Z, Chan C, Lee S, et al. Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis. Nat Commun. 2015;6:6641 pubmed publisher
  79. Wang Y, Han A, Chen E, Singh R, Chichester C, Moore R, et al. The cranberry flavonoids PAC DP-9 and quercetin aglycone induce cytotoxicity and cell cycle arrest and increase cisplatin sensitivity in ovarian cancer cells. Int J Oncol. 2015;46:1924-34 pubmed publisher
  80. Chung Y, Kim H, Park S, Yoon J, Kim M, Nam S, et al. Transcriptome analysis reveals that Müllerian inhibiting substance regulates signaling pathways that contribute to endometrial carcinogenesis. Int J Oncol. 2015;46:2039-46 pubmed publisher
  81. Su C, Zhang C, Tecle A, Fu X, He J, Song J, et al. Tudor staphylococcal nuclease (Tudor-SN), a novel regulator facilitating G1/S phase transition, acting as a co-activator of E2F-1 in cell cycle regulation. J Biol Chem. 2015;290:7208-20 pubmed publisher
  82. Bele A, Mirza S, Zhang Y, Ahmad Mir R, Lin S, Kim J, et al. The cell cycle regulator ecdysoneless cooperates with H-Ras to promote oncogenic transformation of human mammary epithelial cells. Cell Cycle. 2015;14:990-1000 pubmed publisher
  83. Giera S, Deng Y, Luo R, Ackerman S, Mogha A, Monk K, et al. The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun. 2015;6:6121 pubmed publisher
  84. Chipumuro E, Marco E, Christensen C, Kwiatkowski N, Zhang T, Hatheway C, et al. CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer. Cell. 2014;159:1126-1139 pubmed publisher
  85. Eifler M, Uecker R, Weisbach H, Bogdanow B, Richter E, König L, et al. PUL21a-Cyclin A2 interaction is required to protect human cytomegalovirus-infected cells from the deleterious consequences of mitotic entry. PLoS Pathog. 2014;10:e1004514 pubmed publisher
  86. Xu H, Zhou Y, Coughlan K, Ding Y, Wang S, Wu Y, et al. AMPKα1 deficiency promotes cellular proliferation and DNA damage via p21 reduction in mouse embryonic fibroblasts. Biochim Biophys Acta. 2015;1853:65-73 pubmed publisher
  87. Brun C, Périé L, Baraige F, Vernus B, Bonnieu A, Blanquet V. Absence of hyperplasia in Gasp-1 overexpressing mice is dependent on myostatin up-regulation. Cell Physiol Biochem. 2014;34:1241-59 pubmed publisher
  88. Lupino E, Ramondetti C, Buccinnà B, Piccinini M. Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27(KIP1) as a consequence of c-Abl inhibition. Biochem Pharmacol. 2014;92:235-50 pubmed publisher
  89. Dumitrescu A, Aberdeen G, Pepe G, Albrecht E. Placental estrogen suppresses cyclin D1 expression in the nonhuman primate fetal adrenal cortex. Endocrinology. 2014;155:4774-84 pubmed publisher
  90. Yanagi T, Krajewska M, Matsuzawa S, Reed J. PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells. Cancer Res. 2014;74:5795-807 pubmed publisher
  91. Chen K, Yang T, Wu C, Cheng C, Hsu S, Hung H, et al. Pemetrexed induces S-phase arrest and apoptosis via a deregulated activation of Akt signaling pathway. PLoS ONE. 2014;9:e97888 pubmed publisher
  92. Wang Y, Zhou D, Chen S. SGK3 is an androgen-inducible kinase promoting prostate cancer cell proliferation through activation of p70 S6 kinase and up-regulation of cyclin D1. Mol Endocrinol. 2014;28:935-48 pubmed publisher
  93. Machado Neto J, Lazarini M, Favaro P, Franchi G, Nowill A, Saad S, et al. ANKHD1, a novel component of the Hippo signaling pathway, promotes YAP1 activation and cell cycle progression in prostate cancer cells. Exp Cell Res. 2014;324:137-45 pubmed publisher
  94. Qi L, Zhang Y. Truncation of inhibitor of growth family protein 5 effectively induces senescence, but not apoptosis in human tongue squamous cell carcinoma cell line. Tumour Biol. 2014;35:3139-44 pubmed publisher
  95. Ledoux A, Sellier H, Gillies K, Iannetti A, James J, Perkins N. NF?B regulates expression of Polo-like kinase 4. Cell Cycle. 2013;12:3052-62 pubmed publisher
  96. Kazmi S, Byer S, Eckert J, Turk A, Huijbregts R, Brossier N, et al. Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis. Am J Pathol. 2013;182:646-67 pubmed publisher
  97. Diril M, Ratnacaram C, Padmakumar V, Du T, Wasser M, Coppola V, et al. Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration. Proc Natl Acad Sci U S A. 2012;109:3826-31 pubmed publisher
  98. Yang G, Chang B, Yang F, Guo X, Cai K, Xiao X, et al. Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2. Clin Cancer Res. 2010;16:3171-81 pubmed publisher