This is a Validated Antibody Database (VAD) review about rat Cdc42, based on 36 published articles (read how Labome selects the articles), using Cdc42 antibody in all methods. It is aimed to help Labome visitors find the most suited Cdc42 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (11A11)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 6a
In order to elucidate the mechanisms by which filopodia clear pathogens, Cell Signaling Technology Cdc42 antibody (Cell Signaling, 11A11) was used in western blot knockout validation on mouse samples at 1:1000 (fig 6a). J Biol Chem (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (11A11)
  • immunohistochemistry knockout validation; mouse; 1:300; fig s1
In order to study the role of Cdc42 in foregut development and organ bud formation, Cell Signaling Technology Cdc42 antibody (Cell Signaling, 2466) was used in immunohistochemistry knockout validation on mouse samples at 1:300 (fig s1). Biol Open (2016) ncbi
BD Biosciences
mouse monoclonal (44/CDC42)
  • western blot knockout validation; mouse; loading ...; fig 3a
BD Biosciences Cdc42 antibody (BD Biosciences, 610929) was used in western blot knockout validation on mouse samples (fig 3a). J Biol Chem (2018) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:30; loading ...; fig 1c
  • western blot; human; 1:1000; loading ...; fig 1a
In order to study the impact of cell division control 42 homolog on clinicopathological significance Luminal A subtype breast cancer, Invitrogen Cdc42 antibody (LI-COR Biosciences, PA1- 092) was used in immunohistochemistry - paraffin section on human samples at 1:30 (fig 1c) and in western blot on human samples at 1:1000 (fig 1a). Breast Cancer Res Treat (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2e
In order to elucidate the role of endocytic pathways in Andes virus infection, Invitrogen Cdc42 antibody (ThermoFisher Scientific, PA1-092) was used in western blot on human samples at 1:1000 (fig 2e). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3c
In order to investigate the effects of miR-27a on cell migration and invasion in fibroblast-like synoviocytes from rheumatoid arthritis patients, Invitrogen Cdc42 antibody (Thermo Fisher Scientific, PA1-092X) was used in western blot on human samples at 1:1000 (fig 3c). Mol Cells (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4c
In order to determine the enzymatic activity of NarE of Neisseria gonorrhoeae, Invitrogen Cdc42 antibody (Thermo Scientific, PA1-092X) was used in western blot on human samples (fig 4c). FEMS Microbiol Lett (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; fig s2
In order to determine the apical polarity determinants in five patients with microvillus inclusion disease, Invitrogen Cdc42 antibody (Thermo Scientific-Pierce, PA1-092) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig s2). Biol Cell (2016) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 8e
Abcam Cdc42 antibody (Abcam, ab64533) was used in western blot on mouse samples at 1:1000 (fig 8e). Clin Transl Med (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100; fig 5
  • western blot; mouse; fig 5
In order to analyze the participation in the progression of diabetic kidney disease by decreasing Cdc42-GTP activation in podocytes by NMDA receptors, Abcam Cdc42 antibody (Abcam, ab64533) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 5) and in western blot on mouse samples (fig 5). J Pathol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:100; loading ...; fig 6c
Abcam Cdc42 antibody (Abcam, ab64533) was used in western blot on human samples at 1:100 (fig 6c). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig s2
In order to determine the apical polarity determinants in five patients with microvillus inclusion disease, Abcam Cdc42 antibody (Abcam, ab64533) was used in immunohistochemistry - paraffin section on human samples (fig s2). Biol Cell (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (11A11)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology Cdc42 antibody (Cell Signaling, 2466) was used in western blot on human samples (fig 3a). J Biol Chem (2017) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; human; loading ...; fig 2b
In order to observe that chronic presence of internalized Escherichia coli leads to enhanced oncogenicity in colon cancer cells, Cell Signaling Technology Cdc42 antibody (cell signalling, 2466) was used in western blot on human samples (fig 2b). Cell Death Dis (2017) ncbi
domestic rabbit monoclonal (11A11)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 6a
In order to elucidate the mechanisms by which filopodia clear pathogens, Cell Signaling Technology Cdc42 antibody (Cell Signaling, 11A11) was used in western blot knockout validation on mouse samples at 1:1000 (fig 6a). J Biol Chem (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1i
In order to study the mechanism of internalization of CXCR4 receptor dependent on MIM and small Rab GTPases., Cell Signaling Technology Cdc42 antibody (CST, 2462S) was used in western blot on human samples (fig 1i). J Cell Sci (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s3i
Cell Signaling Technology Cdc42 antibody (Cell Signaling, 2462) was used in western blot on human samples at 1:1000 (fig s3i). J Cell Biol (2017) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; human; loading ...; fig s4a
Cell Signaling Technology Cdc42 antibody (Cell signaling, 2466P) was used in western blot on human samples (fig s4a). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4d
  • western blot; human; loading ...; fig 4c
In order to explore how extracellular translationally controlled tumor protein affects colon cancer progression, Cell Signaling Technology Cdc42 antibody (Cell Signaling Technology, 2462) was used in immunocytochemistry on human samples (fig 4d) and in western blot on human samples (fig 4c). Oncotarget (2016) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology Cdc42 antibody (Cell Signaling, 2466) was used in western blot on human samples (fig 6c). J Biol Chem (2016) ncbi
domestic rabbit monoclonal (11A11)
  • immunohistochemistry knockout validation; mouse; 1:300; fig s1
In order to study the role of Cdc42 in foregut development and organ bud formation, Cell Signaling Technology Cdc42 antibody (Cell Signaling, 2466) was used in immunohistochemistry knockout validation on mouse samples at 1:300 (fig s1). Biol Open (2016) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; human; loading ...; fig 10e
In order to investigate the role of CD73 in endometrial cancer, Cell Signaling Technology Cdc42 antibody (Cell Signaling, 11A11) was used in western blot on human samples (fig 10e). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; human; loading ...; fig 2f
Cell Signaling Technology Cdc42 antibody (Cell Signaling, 2466) was used in western blot on human samples (fig 2f). Sci Rep (2015) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; human; 1:5000; fig 3
In order to examine the role of Cdc42 in enterocyte polarization, Cell Signaling Technology Cdc42 antibody (Cell Signalling Technology, 11A11) was used in western blot on human samples at 1:5000 (fig 3). J Cell Biol (2015) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; rat; 1:500; fig 5
Cell Signaling Technology Cdc42 antibody (Cell Signaling, 11A11) was used in western blot on rat samples at 1:500 (fig 5). Front Cell Neurosci (2015) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; human; fig s9
In order to study promotion of collective invasion by an epigenetically distinct breast cancer cell subpopulation, Cell Signaling Technology Cdc42 antibody (Cell Signaling Technology, 11A11) was used in western blot on human samples (fig s9). J Clin Invest (2015) ncbi
domestic rabbit monoclonal (11A11)
  • western blot; mouse; fig 1
Cell Signaling Technology Cdc42 antibody (Cell signaling, 2466) was used in western blot on mouse samples (fig 1). Cancer Res (2014) ncbi
BD Biosciences
mouse monoclonal (44/CDC42)
  • western blot; human; 1:200; loading ...; fig 6d
BD Biosciences Cdc42 antibody (BD Biosciences, 610928) was used in western blot on human samples at 1:200 (fig 6d). Nat Commun (2021) ncbi
mouse monoclonal (44/CDC42)
  • immunoprecipitation; mouse; loading ...; fig 6c
BD Biosciences Cdc42 antibody (BD Biosciences, 610928) was used in immunoprecipitation on mouse samples (fig 6c). FASEB J (2019) ncbi
mouse monoclonal (44/CDC42)
  • western blot; mouse; loading ...; fig 6b
BD Biosciences Cdc42 antibody (BD Biosciences, 610928) was used in western blot on mouse samples (fig 6b). Immunity (2019) ncbi
mouse monoclonal (44/CDC42)
  • western blot knockout validation; mouse; loading ...; fig 3a
BD Biosciences Cdc42 antibody (BD Biosciences, 610929) was used in western blot knockout validation on mouse samples (fig 3a). J Biol Chem (2018) ncbi
mouse monoclonal (44/CDC42)
  • western blot; rat; loading ...; fig 3c
In order to perform whole exome sequencing to identify recessive causes of steroid-resistant nephrotic syndrome, BD Biosciences Cdc42 antibody (BD Transduction Laboratories, 610928) was used in western blot on rat samples (fig 3c). J Clin Invest (2017) ncbi
mouse monoclonal (44/CDC42)
  • western blot; mouse; fig 8
BD Biosciences Cdc42 antibody (BD Transduction Laboratories, 610929) was used in western blot on mouse samples (fig 8). Cell Death Dis (2017) ncbi
mouse monoclonal (44/CDC42)
  • western blot; human; fig 1s1
BD Biosciences Cdc42 antibody (BD Transduction Laboratories, 610929) was used in western blot on human samples (fig 1s1). elife (2016) ncbi
mouse monoclonal (44/CDC42)
  • immunocytochemistry; human; 1:300; fig s5i
  • western blot; human; 1:300; fig s5f
In order to identify factors that regulate the stability of the RhoA zone, BD Biosciences Cdc42 antibody (BD Biosciences, 610928) was used in immunocytochemistry on human samples at 1:300 (fig s5i) and in western blot on human samples at 1:300 (fig s5f). Nat Cell Biol (2015) ncbi
mouse monoclonal (44/CDC42)
  • western blot; mouse; fig 4
BD Biosciences Cdc42 antibody (Becton Dickinson, 610928) was used in western blot on mouse samples (fig 4). Mol Biol Cell (2015) ncbi
mouse monoclonal (44/CDC42)
  • western blot; human; fig s5
BD Biosciences Cdc42 antibody (BD Transduction Laboratories, 610929) was used in western blot on human samples (fig s5). Hum Genet (2015) ncbi
mouse monoclonal (44/CDC42)
  • western blot; zebrafish ; fig 1d
BD Biosciences Cdc42 antibody (BD Transduction Laboratories, 610929) was used in western blot on zebrafish samples (fig 1d). Invest Ophthalmol Vis Sci (2015) ncbi
mouse monoclonal (44/CDC42)
  • immunocytochemistry; human; fig s4g
BD Biosciences Cdc42 antibody (BD, 610929) was used in immunocytochemistry on human samples (fig s4g). J Cell Biol (2015) ncbi
mouse monoclonal (44/CDC42)
  • western blot; mouse; 1:1000
In order to study the role of cell migration in the mechanism by which overexpression of Cdc42 promotes developing mammary gland hyperbranching, BD Biosciences Cdc42 antibody (BD Transduction Laboratories, 610929) was used in western blot on mouse samples at 1:1000. Breast Cancer Res (2013) ncbi
Articles Reviewed
  1. Fayad R, Rojas M, Partisani M, Finetti P, Dib S, Abélanet S, et al. EFA6B regulates a stop signal for collective invasion in breast cancer. Nat Commun. 2021;12:2198 pubmed publisher
  2. Li B, Wang Z, Hong J, Che Y, Chen R, Hu Z, et al. Iron deficiency promotes aortic medial degeneration via destructing cytoskeleton of vascular smooth muscle cells. Clin Transl Med. 2021;11:e276 pubmed publisher
  3. Huang K, Ru B, Zhang Y, Chan W, Chow S, Zhang J, et al. Sertoli cell-specific coxsackievirus and adenovirus receptor knockout regulates cell adhesion and gene transcription via β-catenin inactivation and Cdc42 activation. FASEB J. 2019;33:7588-7602 pubmed publisher
  4. Lin C, Zhang Y, Zhang K, Zheng Y, Lu L, Chang H, et al. Fever Promotes T Lymphocyte Trafficking via a Thermal Sensory Pathway Involving Heat Shock Protein 90 and α4 Integrins. Immunity. 2019;50:137-151.e6 pubmed publisher
  5. Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
  6. Chrysanthou E, Gorringe K, Joseph C, Craze M, Nolan C, Diez Rodriguez M, et al. Phenotypic characterisation of breast cancer: the role of CDC42. Breast Cancer Res Treat. 2017;164:317-325 pubmed publisher
  7. Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher
  8. Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  9. Horsthemke M, Bachg A, Groll K, Moyzio S, Müther B, Hemkemeyer S, et al. Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion. J Biol Chem. 2017;292:7258-7273 pubmed publisher
  10. Li L, Baxter S, Gu N, Ji M, Zhan X. Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases. J Cell Sci. 2017;130:1475-1485 pubmed publisher
  11. Lovric S, Gonçalves S, Gee H, Oskouian B, Srinivas H, Choi W, et al. Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017;127:912-928 pubmed publisher
  12. Han F, Liu C, Zhang L, Zhou Y, Qin Y, Wang Y, et al. Globozoospermia and lack of acrosome formation in GM130-deficient mice. Cell Death Dis. 2017;8:e2532 pubmed publisher
  13. Rafiq N, Lieu Z, Jiang T, Yu C, Matsudaira P, Jones G, et al. Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO. J Cell Biol. 2017;216:181-197 pubmed publisher
  14. Chiang C, Flint M, Lin J, Spiropoulou C. Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells. PLoS ONE. 2016;11:e0164768 pubmed publisher
  15. Liu Z, Chu S, Yao S, Li Y, Fan S, Sun X, et al. CD74 interacts with CD44 and enhances tumorigenesis and metastasis via RHOA-mediated cofilin phosphorylation in human breast cancer cells. Oncotarget. 2016;7:68303-68313 pubmed publisher
  16. Shi D, Shi G, Xie J, Du X, Yang H. MicroRNA-27a Inhibits Cell Migration and Invasion of Fibroblast-Like Synoviocytes by Targeting Follistatin-Like Protein 1 in Rheumatoid Arthritis. Mol Cells. 2016;39:611-8 pubmed publisher
  17. Rodas P, Álamos Musre A, Álvarez F, Escobar A, Tapia C, Osorio E, et al. The NarE protein of Neisseria gonorrhoeae catalyzes ADP-ribosylation of several ADP-ribose acceptors despite an N-terminal deletion. FEMS Microbiol Lett. 2016;363: pubmed publisher
  18. Xiao B, Chen D, Luo S, Hao W, Jing F, Liu T, et al. Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. Oncotarget. 2016;7:50057-50073 pubmed publisher
  19. Shen J, Wang R, He Z, Huang H, He X, Zhou J, et al. NMDA receptors participate in the progression of diabetic kidney disease by decreasing Cdc42-GTP activation in podocytes. J Pathol. 2016;240:149-60 pubmed publisher
  20. Mounir Z, Korn J, Westerling T, Lin F, Kirby C, Schirle M, et al. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor. elife. 2016;5: pubmed publisher
  21. Wynn M, Yates J, Evans C, Van Wassenhove L, Wu Z, Bridges S, et al. RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells. J Biol Chem. 2016;291:13715-29 pubmed publisher
  22. Liu S, Zhou F, Shen Y, Zhang Y, Yin H, Zeng Y, et al. Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget. 2016;7:32876-92 pubmed publisher
  23. Loebel D, Plageman T, Tang T, Jones V, Muccioli M, Tam P. Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction. Biol Open. 2016;5:130-9 pubmed publisher
  24. Bowser J, Blackburn M, Shipley G, Molina J, Dunner K, Broaddus R. Loss of CD73-mediated actin polymerization promotes endometrial tumor progression. J Clin Invest. 2016;126:220-38 pubmed publisher
  25. Shrivastava A, Prasad A, Kuzontkoski P, Yu J, Groopman J. Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements. Sci Rep. 2015;5:16833 pubmed publisher
  26. Michaux G, Massey Harroche D, Nicolle O, Rabant M, Brousse N, Goulet O, et al. The localisation of the apical Par/Cdc42 polarity module is specifically affected in microvillus inclusion disease. Biol Cell. 2016;108:19-28 pubmed publisher
  27. Bruurs L, Donker L, Zwakenberg S, Zwartkruis F, Begthel H, Knisely A, et al. ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization. J Cell Biol. 2015;210:1055-63 pubmed publisher
  28. Priya R, Gomez G, Budnar S, Verma S, Cox H, Hamilton N, et al. Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nat Cell Biol. 2015;17:1282-93 pubmed publisher
  29. Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, et al. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015;26:3489-503 pubmed publisher
  30. Bijata M, Wlodarczyk J, Figiel I. Dystroglycan controls dendritic morphogenesis of hippocampal neurons in vitro. Front Cell Neurosci. 2015;9:199 pubmed publisher
  31. Hwang D, Kohl S, Fan X, Vivante A, Chan S, Dworschak G, et al. Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. Hum Genet. 2015;134:905-16 pubmed publisher
  32. Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
  33. Westcott J, Prechtl A, Maine E, Dang T, Esparza M, Sun H, et al. An epigenetically distinct breast cancer cell subpopulation promotes collective invasion. J Clin Invest. 2015;125:1927-43 pubmed publisher
  34. Artym V, Swatkoski S, Matsumoto K, Campbell C, Petrie R, Dimitriadis E, et al. Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network. J Cell Biol. 2015;208:331-50 pubmed publisher
  35. Sakamori R, Yu S, Zhang X, Hoffman A, Sun J, Das S, et al. CDC42 inhibition suppresses progression of incipient intestinal tumors. Cancer Res. 2014;74:5480-92 pubmed publisher
  36. Bray K, Gillette M, Young J, Loughran E, Hwang M, Sears J, et al. Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration. Breast Cancer Res. 2013;15:R91 pubmed