This is a Validated Antibody Database (VAD) review about rat Cd8b, based on 18 published articles (read how Labome selects the articles), using Cd8b antibody in all methods. It is aimed to help Labome visitors find the most suited Cd8b antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cd8b synonym: Cd8b1; T-cell surface glycoprotein CD8 beta chain; CD8 antigen 37 kDa chain; CD8 antigen beta-chain; OX-8 membrane antigen

Invitrogen
mouse monoclonal (eBio341 (341))
  • flow cytometry; rat; loading ...; fig s1j
Invitrogen Cd8b antibody (eBioscience, eBio341) was used in flow cytometry on rat samples (fig s1j). Nature (2019) ncbi
mouse monoclonal (OX-8)
  • flow cytometry; rat; loading ...; fig s1a
In order to examine the effect of Bifidobacterium breve M-16V administration on the maturation of the intestinal and circulating immune system during suckling, Invitrogen Cd8b antibody (Caltag, OX-8) was used in flow cytometry on rat samples (fig s1a). PLoS ONE (2016) ncbi
mouse monoclonal (eBio341 (341))
  • flow cytometry; mouse; fig 1b
Invitrogen Cd8b antibody (eBioscience, eBio341) was used in flow cytometry on mouse samples (fig 1b). Nat Immunol (2014) ncbi
mouse monoclonal (OX-8)
  • flow cytometry; rat
In order to study the innate immune responses to bacterial components using HLA-B27 transgenic rats, Invitrogen Cd8b antibody (Invitrogen, OX-8) was used in flow cytometry on rat samples . Inflamm Bowel Dis (2008) ncbi
mouse monoclonal (OX-8)
  • flow cytometry; rat; tbl 1
In order to determine the role of T cells in the development of colitis in Bacteroides vulgatus-monoassociated HLA-B27 TG rats, Invitrogen Cd8b antibody (Caltag, OX-8) was used in flow cytometry on rat samples (tbl 1). Inflamm Bowel Dis (2007) ncbi
mouse monoclonal (OX-8)
  • flow cytometry; rat; tbl 1
In order to test if HLA-B27 expression on T cells is required for development of colitis, Invitrogen Cd8b antibody (Caltag, OX-8) was used in flow cytometry on rat samples (tbl 1). Clin Exp Immunol (2006) ncbi
mouse monoclonal (OX-8)
  • flow cytometry; rat
In order to examine the regulation of in vitro T-cell responses to enteric bacterial components, Invitrogen Cd8b antibody (Caltag, OX-8) was used in flow cytometry on rat samples . Immunology (2005) ncbi
mouse monoclonal (OX-8)
  • flow cytometry; rat; fig 5
In order to use transgenic rats to investigate host-dependent immune responses to commensal caecal bacteria, Invitrogen Cd8b antibody (Caltag, OX-8) was used in flow cytometry on rat samples (fig 5). Clin Exp Immunol (2004) ncbi
mouse monoclonal (OX-8)
  • immunohistochemistry; rat; 1:25; fig 4
In order to elucidate the role of adhesion molecules in the pathogenesis of experimental allergic myositis, Invitrogen Cd8b antibody (Caltag, OX-8) was used in immunohistochemistry on rat samples at 1:25 (fig 4). Muscle Nerve (2002) ncbi
mouse monoclonal (IF4/OX-8)
  • flow cytometry; rat
In order to discuss tolerance to ACI heart allografts using rats, Invitrogen Cd8b antibody (caltag, if4) was used in flow cytometry on rat samples . Transplantation (2000) ncbi
mouse monoclonal (IF4/OX-8)
  • flow cytometry; rat; fig 1
In order to study tolerance induction using heart allografts in Lewis rat, Invitrogen Cd8b antibody (Caltag, IF4) was used in flow cytometry on rat samples (fig 1). Transplantation (1999) ncbi
mouse monoclonal (OX-8)
  • immunohistochemistry; rat; 1:100
In order to test if IL-4 can protect from malignant gliomas in vivo, Invitrogen Cd8b antibody (Biosource, MRC OX-8) was used in immunohistochemistry on rat samples at 1:100. Cancer Res (1999) ncbi
mouse monoclonal (IF4/OX-8)
  • flow cytometry; rat
In order to discuss factors that promote tolerance in a rat ACI heart allografts model, Invitrogen Cd8b antibody (Caltag, if4) was used in flow cytometry on rat samples . Transplantation (1998) ncbi
mouse monoclonal (IF4/OX-8)
  • flow cytometry; rat
In order to determine the subset(s) of cells in donor blood that promote long-term allograft survival in rats, Invitrogen Cd8b antibody (caltag, if4) was used in flow cytometry on rat samples . Transplantation (1998) ncbi
mouse monoclonal (OX-8)
  • immunohistochemistry; rat; 1:200; fig 6
In order to study the effects of IL-4 using the HSV-tk/GCV system of glioma gene therapy, Invitrogen Cd8b antibody (Biosource, MRC OX-8) was used in immunohistochemistry on rat samples at 1:200 (fig 6). Hum Gene Ther (1997) ncbi
mouse monoclonal (OX-8)
  • immunoprecipitation; rat; 0.5 mg/ml; fig 2
In order to use W3/25 and MRC OX-8 to study rat T cell populations, Invitrogen Cd8b antibody (noco, MRC OX-8) was used in immunoprecipitation on rat samples at 0.5 mg/ml (fig 2). Eur J Immunol (1983) ncbi
Miltenyi Biotec
human monoclonal (REA222)
  • flow cytometry; rat; 1:100; loading ...; fig 6f
Miltenyi Biotec Cd8b antibody (Miltenyi Biotec, 130-103-322) was used in flow cytometry on rat samples at 1:100 (fig 6f). PLoS ONE (2017) ncbi
Bio-Rad
mouse monoclonal (341)
  • flow cytometry; rat; loading ...; fig s1d
In order to examine the effect of Bifidobacterium breve M-16V administration on the maturation of the intestinal and circulating immune system during suckling, Bio-Rad Cd8b antibody (Serotec, 3.41) was used in flow cytometry on rat samples (fig s1d). PLoS ONE (2016) ncbi
Biorbyt
rabbit polyclonal
  • flow cytometry; mouse; loading ...; fig 6b
Biorbyt Cd8b antibody (Biorbyt, orb1269) was used in flow cytometry on mouse samples (fig 6b). Front Microbiol (2018) ncbi
Articles Reviewed
  1. Lodygin D, Hermann M, Schweingruber N, Flügel Koch C, Watanabe T, Schlosser C, et al. β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration. Nature. 2019;566:503-508 pubmed publisher
  2. Brun P, Scarpa M, Marchiori C, Conti J, Kotsafti A, Porzionato A, et al. Herpes Simplex Virus Type 1 Engages Toll Like Receptor 2 to Recruit Macrophages During Infection of Enteric Neurons. Front Microbiol. 2018;9:2148 pubmed publisher
  3. Lang S, Li L, Wang X, Sun J, Xue X, Xiao Y, et al. CXCL10/IP-10 Neutralization Can Ameliorate Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome in Rats. PLoS ONE. 2017;12:e0169100 pubmed publisher
  4. Rigo Adrover M, Franch A, Castell M, Pérez Cano F. Preclinical Immunomodulation by the Probiotic Bifidobacterium breve M-16V in Early Life. PLoS ONE. 2016;11:e0166082 pubmed publisher
  5. Backer R, Helbig C, Gentek R, Kent A, Laidlaw B, Dominguez C, et al. A central role for Notch in effector CD8(+) T cell differentiation. Nat Immunol. 2014;15:1143-51 pubmed publisher
  6. Qian B, Tonkonogy S, Sartor R. Aberrant innate immune responses in TLR-ligand activated HLA-B27 transgenic rat cells. Inflamm Bowel Dis. 2008;14:1358-65 pubmed publisher
  7. Hoentjen F, Tonkonogy S, Qian B, Liu B, Dieleman L, Sartor R. CD4(+) T lymphocytes mediate colitis in HLA-B27 transgenic rats monoassociated with nonpathogenic Bacteroides vulgatus. Inflamm Bowel Dis. 2007;13:317-24 pubmed
  8. Hoentjen F, Tonkonogy S, Liu B, Sartor R, Taurog J, Dieleman L. Adoptive transfer of nontransgenic mesenteric lymph node cells induces colitis in athymic HLA-B27 transgenic nude rats. Clin Exp Immunol. 2006;143:474-83 pubmed
  9. Qian B, Tonkonogy S, Hoentjen F, Dieleman L, Sartor R. Dysregulated luminal bacterial antigen-specific T-cell responses and antigen-presenting cell function in HLA-B27 transgenic rats with chronic colitis. Immunology. 2005;116:112-21 pubmed
  10. Dieleman L, Hoentjen F, Qian B, Sprengers D, Tjwa E, Torres M, et al. Reduced ratio of protective versus proinflammatory cytokine responses to commensal bacteria in HLA-B27 transgenic rats. Clin Exp Immunol. 2004;136:30-9 pubmed
  11. Ito T, Kumamoto T, Horinouchi H, Yukishige K, Sugihara R, Fujimoto S, et al. Adhesion molecule expression in experimental myositis. Muscle Nerve. 2002;25:409-18 pubmed
  12. Lan F, Hayamizu K, Strober S. Cyclosporine facilitates chimeric and inhibits nonchimeric tolerance after posttransplant total lymphoid irradiation. Transplantation. 2000;69:649-55 pubmed
  13. Hayamizu K, Lan F, Huie P, Sibley R, Strober S. Comparison of chimeric acid and non-chimeric tolerance using posttransplant total lymphoid irradiation: cytokine expression and chronic rejection. Transplantation. 1999;68:1036-44 pubmed
  14. Benedetti S, Bruzzone M, Pollo B, DiMeco F, Magrassi L, Pirola B, et al. Eradication of rat malignant gliomas by retroviral-mediated, in vivo delivery of the interleukin 4 gene. Cancer Res. 1999;59:645-52 pubmed
  15. Hayamizu K, Huie P, Sibley R, Strober S. Monocyte-derived dendritic cell precursors facilitate tolerance to heart allografts after total lymphoid irradiation. Transplantation. 1998;66:1285-91 pubmed
  16. Hayamizu K, Zeng D, Huie P, Garcia Ojeda M, Bloch D, Fong L, et al. Donor blood monocytes but not T or B cells facilitate long-term allograft survival after total lymphoid irradiation. Transplantation. 1998;66:585-93 pubmed
  17. Benedetti S, DiMeco F, Pollo B, Cirenei N, Colombo B, Bruzzone M, et al. Limited efficacy of the HSV-TK/GCV system for gene therapy of malignant gliomas and perspectives for the combined transduction of the interleukin-4 gene. Hum Gene Ther. 1997;8:1345-53 pubmed
  18. Thomas M, Green J. Molecular nature of the W3/25 and MRC OX-8 marker antigens for rat T lymphocytes: comparisons with mouse and human antigens. Eur J Immunol. 1983;13:855-8 pubmed