This is a Validated Antibody Database (VAD) review about rat Cd74, based on 9 published articles (read how Labome selects the articles), using Cd74 antibody in all methods. It is aimed to help Labome visitors find the most suited Cd74 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cd74 synonym: INVG34

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal
  • western blot knockout validation; mouse; loading ...; fig 4d
  • flow cytometry; human; loading ...; fig 1g
  • immunohistochemistry; human; loading ...; fig 1b
Santa Cruz Biotechnology Cd74 antibody (Santa Cruz, LN-2) was used in western blot knockout validation on mouse samples (fig 4d), in flow cytometry on human samples (fig 1g) and in immunohistochemistry on human samples (fig 1b). Cell Mol Gastroenterol Hepatol (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal (LN-2)
  • western blot knockout validation; mouse; loading ...; fig 4d
  • flow cytometry; human; loading ...; fig 1g
  • immunohistochemistry; human; loading ...; fig 1b
Santa Cruz Biotechnology Cd74 antibody (Santa Cruz, LN-2) was used in western blot knockout validation on mouse samples (fig 4d), in flow cytometry on human samples (fig 1g) and in immunohistochemistry on human samples (fig 1b). Cell Mol Gastroenterol Hepatol (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal (LN-2)
  • western blot knockout validation; mouse; loading ...; fig 4d
  • flow cytometry; human; loading ...; fig 1g
  • immunohistochemistry; human; loading ...; fig 1b
Santa Cruz Biotechnology Cd74 antibody (Santa Cruz, LN-2) was used in western blot knockout validation on mouse samples (fig 4d), in flow cytometry on human samples (fig 1g) and in immunohistochemistry on human samples (fig 1b). Cell Mol Gastroenterol Hepatol (2020) ncbi
mouse monoclonal
  • western blot knockout validation; mouse; loading ...; fig 4d
  • flow cytometry; human; loading ...; fig 1g
  • immunohistochemistry; human; loading ...; fig 1b
Santa Cruz Biotechnology Cd74 antibody (Santa Cruz, LN-2) was used in western blot knockout validation on mouse samples (fig 4d), in flow cytometry on human samples (fig 1g) and in immunohistochemistry on human samples (fig 1b). Cell Mol Gastroenterol Hepatol (2020) ncbi
mouse monoclonal
  • western blot; human; fig 2b
Santa Cruz Biotechnology Cd74 antibody (Santa Cruz Biotechnology, LN-2) was used in western blot on human samples (fig 2b). J Immunol (2019) ncbi
mouse monoclonal (LN-2)
  • western blot; human; fig 2b
Santa Cruz Biotechnology Cd74 antibody (Santa Cruz Biotechnology, LN-2) was used in western blot on human samples (fig 2b). J Immunol (2019) ncbi
mouse monoclonal (PIN.1)
  • western blot; human; 1:500; loading ...; fig 2b
In order to study the antigen presentation by HLA-DP84Gly through the class I antigen processing pathway, Santa Cruz Biotechnology Cd74 antibody (Santa Cruz Biotechnology, sc-47742) was used in western blot on human samples at 1:500 (fig 2b). Nat Commun (2017) ncbi
mouse monoclonal (CerCLIP.1)
  • immunoprecipitation; human; loading ...; fig 2c
  • western blot; human; 1:3000; loading ...; fig 2a
In order to study the antigen presentation by HLA-DP84Gly through the class I antigen processing pathway, Santa Cruz Biotechnology Cd74 antibody (Santa Cruz Biotechnology, sc-12725) was used in immunoprecipitation on human samples (fig 2c) and in western blot on human samples at 1:3000 (fig 2a). Nat Commun (2017) ncbi
mouse monoclonal (LN-2)
  • immunocytochemistry; human; 1:200; loading ...; fig 3h
  • western blot; human; 1:1000; loading ...; fig 2b
In order to study the antigen presentation by HLA-DP84Gly through the class I antigen processing pathway, Santa Cruz Biotechnology Cd74 antibody (Santa Cruz Biotechnology, sc-6262) was used in immunocytochemistry on human samples at 1:200 (fig 3h) and in western blot on human samples at 1:1000 (fig 2b). Nat Commun (2017) ncbi
mouse monoclonal (LN-2)
  • blocking or activating experiments; human
  • flow cytometry; human; fig 2b
In order to explore how the CD74/CD44 MIF receptor contributes to rheumatoid arthritis, Santa Cruz Biotechnology Cd74 antibody (Santa Cruz, LN2) was used in blocking or activating experiments on human samples and in flow cytometry on human samples (fig 2b). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal
  • flow cytometry; human; fig 2b
In order to explore how the CD74/CD44 MIF receptor contributes to rheumatoid arthritis, Santa Cruz Biotechnology Cd74 antibody (Santa Cruz, LN2) was used in flow cytometry on human samples (fig 2b). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (CerCLIP.1)
  • flow cytometry; human; loading ...; fig 1a
In order to study Type 1 diabetes, HLA-DQ2 and DQ8 molecules, and HLA-DM effect on invariant chain-derived CLIP peptides, Santa Cruz Biotechnology Cd74 antibody (SantaCruz, Cer.CLIP1) was used in flow cytometry on human samples (fig 1a). Eur J Immunol (2016) ncbi
mouse monoclonal (LN-2)
  • ELISA; human; fig 2
Santa Cruz Biotechnology Cd74 antibody (Santa Cruz, sc-6262) was used in ELISA on human samples (fig 2). Antioxid Redox Signal (2015) ncbi
mouse monoclonal (D-6)
  • flow cytometry; mouse
Santa Cruz Biotechnology Cd74 antibody (Santa Cruz, sc-137217) was used in flow cytometry on mouse samples . Monoclon Antib Immunodiagn Immunother (2014) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; fig s4b
  • western blot; mouse; loading ...; fig s2d
Abcam Cd74 antibody (Abcam, Ab180779) was used in western blot on human samples (fig s4b) and in western blot on mouse samples (fig s2d). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • flow cytometry; mouse; loading ...; fig s1
In order to show that ABCA7 regulates natural killer T cell development in a cell-extrinsic manner, Abcam Cd74 antibody (Abcam, ab180779) was used in flow cytometry on mouse samples (fig s1). Sci Rep (2017) ncbi
Articles Reviewed
  1. Kumar A, Sundaram K, Mu J, Dryden G, Sriwastva M, Lei C, et al. High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance. Nat Commun. 2021;12:213 pubmed publisher
  2. Farr L, Ghosh S, Jiang N, Watanabe K, Parlak M, Bucala R, et al. CD74 Signaling Links Inflammation to Intestinal Epithelial Cell Regeneration and Promotes Mucosal Healing. Cell Mol Gastroenterol Hepatol. 2020;10:101-112 pubmed publisher
  3. Crivello P, Ahci M, Maaßen F, Wossidlo N, Arrieta Bolaños E, Heinold A, et al. Multiple Knockout of Classical HLA Class II β-Chains by CRISPR/Cas9 Genome Editing Driven by a Single Guide RNA. J Immunol. 2019;202:1895-1903 pubmed publisher
  4. Yamashita Y, Anczurowski M, Nakatsugawa M, Tanaka M, Kagoya Y, Sinha A, et al. HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway. Nat Commun. 2017;8:15244 pubmed publisher
  5. Nowyhed H, Chandra S, Kiosses W, Marcovecchio P, Andary F, Zhao M, et al. ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content. Sci Rep. 2017;7:40273 pubmed publisher
  6. Yoo S, Leng L, Kim B, Du X, Tilstam P, Kim K, et al. MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2016;113:E7917-E7926 pubmed
  7. Zhou Z, Reyes Vargas E, Escobar H, Rudd B, Rockwood A, Delgado J, et al. Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptides. Eur J Immunol. 2016;46:834-45 pubmed publisher
  8. Stoppe C, Rex S, Goetzenich A, Kraemer S, Emontzpohl C, Soppert J, et al. Interaction of MIF Family Proteins in Myocardial Ischemia/Reperfusion Damage and Their Influence on Clinical Outcome of Cardiac Surgery Patients. Antioxid Redox Signal. 2015;23:865-79 pubmed publisher
  9. Genève L, Gauthier C, Thibodeau J. The D-6 mouse monoclonal antibody recognizes the CD74 cytoplasmic tail. Monoclon Antib Immunodiagn Immunother. 2014;33:221-7 pubmed publisher