This is a Validated Antibody Database (VAD) review about rat Ccn2, based on 28 published articles (read how Labome selects the articles), using Ccn2 antibody in all methods. It is aimed to help Labome visitors find the most suited Ccn2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ccn2 synonym: CTGRP; Ctgf

Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3b
  • western blot; human; loading ...; fig 4b
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on mouse samples (fig 3b) and in western blot on human samples (fig 4b). Oxid Med Cell Longev (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3a
  • immunohistochemistry; human; 1:100; loading ...; fig 7c
Abcam Ccn2 antibody (Abcam, 227180) was used in western blot on mouse samples at 1:1000 (fig 3a) and in immunohistochemistry on human samples at 1:100 (fig 7c). J Clin Invest (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...
Abcam Ccn2 antibody (abcam, ab6992) was used in immunohistochemistry on mouse samples . Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2c
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on mouse samples (fig 2c). J Cell Mol Med (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3b
  • western blot; mouse; 1:2000; loading ...; fig 3a, 3h
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig s7
  • western blot; human; 1:2000; loading ...; fig 4m
Abcam Ccn2 antibody (Abcam, ab6992) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 3b), in western blot on mouse samples at 1:2000 (fig 3a, 3h), in immunohistochemistry - paraffin section on human samples at 1:200 (fig s7) and in western blot on human samples at 1:2000 (fig 4m). J Am Heart Assoc (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 2f
Abcam Ccn2 antibody (Abcam, ab6992) was used in immunocytochemistry on human samples (fig 2f). Int J Mol Sci (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2l
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on human samples at 1:1000 (fig 2l). Mol Cancer (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6d
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on mouse samples (fig 6d). JACC Basic Transl Sci (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; zebrafish ; 1:150; loading ...; fig 7a
  • immunocytochemistry; human; 1:200; loading ...; fig 4b
  • western blot; human; loading ...; fig 4b
Abcam Ccn2 antibody (Abcam, ab6992) was used in immunohistochemistry on zebrafish samples at 1:150 (fig 7a), in immunocytochemistry on human samples at 1:200 (fig 4b) and in western blot on human samples (fig 4b). Nat Cell Biol (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 4a
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on human samples at 1:1000 (fig 4a). Invest Ophthalmol Vis Sci (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6d
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on mouse samples at 1:1000 (fig 6d). J Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
In order to report that A549 cell death induced by sodium butyrate and sodium 4-phenylbutyrate occur via distinct pathways, Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on human samples (fig 2c). Cancer Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s1e
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on human samples at 1:1000 (fig s1e). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 1a,s3a
  • western blot; mouse; 1:500; loading ...; fig 1g
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on human samples at 1:500 (fig 1a,s3a) and in western blot on mouse samples at 1:500 (fig 1g). Gastroenterology (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5a
In order to determine the effects of high glucose on the epithelial-mesenchymal transition in retinal pigment epithelial cells, Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on human samples (fig 5a). Int J Mol Med (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2h
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on human samples (fig 2h). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:500; loading ...; fig 3b
  • western blot; human; 1:500; loading ...; fig 3b
Abcam Ccn2 antibody (Abcam, 5097) was used in western blot on rat samples at 1:500 (fig 3b) and in western blot on human samples at 1:500 (fig 3b). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:5000; loading ...; fig 6d
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on mouse samples at 1:5000 (fig 6d). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 2b
Abcam Ccn2 antibody (Abcam, ab6992) was used in western blot on rat samples (fig 2b). Drug Des Devel Ther (2016) ncbi
domestic rabbit polyclonal
Abcam Ccn2 antibody (Abcam, ab6992) was used . Biomed Res Int (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-6)
  • western blot; mouse; loading ...; fig 7a
Santa Cruz Biotechnology Ccn2 antibody (Santa Cruz Biotechnology, sc-373936) was used in western blot on mouse samples (fig 7a). Sci Rep (2021) ncbi
mouse monoclonal (E-5)
  • western blot; mouse; loading ...; fig 3d
Santa Cruz Biotechnology Ccn2 antibody (Santa Cruz, sc-365970) was used in western blot on mouse samples (fig 3d). Mol Brain (2021) ncbi
mouse monoclonal (B-6)
  • western blot; mouse; 0.2 ug/ml; loading ...; fig 4b
Santa Cruz Biotechnology Ccn2 antibody (Santa Cruz, sc-373936) was used in western blot on mouse samples at 0.2 ug/ml (fig 4b). Adv Sci (Weinh) (2021) ncbi
mouse monoclonal (E-5)
  • western blot; human; 1:100; loading ...; fig 4c
Santa Cruz Biotechnology Ccn2 antibody (Santa Cruz, sc-365970) was used in western blot on human samples at 1:100 (fig 4c). elife (2020) ncbi
mouse monoclonal (E-5)
  • immunocytochemistry; human; 1:50; loading ...; fig 4c32
Santa Cruz Biotechnology Ccn2 antibody (Santa Cruz Biotechnology, sc-365970) was used in immunocytochemistry on human samples at 1:50 (fig 4c32). Ocul Surf (2019) ncbi
mouse monoclonal (B-6)
  • western blot; rat; 1:1000; loading ...; fig 2b
Santa Cruz Biotechnology Ccn2 antibody (Santa Cruz, sc-373936) was used in western blot on rat samples at 1:1000 (fig 2b). BMC Nephrol (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3d
In order to find that fibulin-6 knockdown fibroblasts affect TGF-beta dependent migration, stress fiber formation, cellular networking, and fibroblast wound contraction, Invitrogen Ccn2 antibody (Thermo Scientific, PA1-22376) was used in western blot on mouse samples (fig 3d). Sci Rep (2017) ncbi
domestic rabbit polyclonal
In order to study the synergistic effect of simvastatin plus radiation therapy on the proliferation and survival of gastric and colorectal cancer, Invitrogen Ccn2 antibody (Thermo Scientific, PA5-32193) was used . Int J Radiat Oncol Biol Phys (2015) ncbi
Articles Reviewed
  1. Fang L, Wang W, Chen J, Zuo A, Gao H, Yan T, et al. Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice. Oxid Med Cell Longev. 2021;2021:3309944 pubmed publisher
  2. Bansod S, Saifi M, Godugu C. Inhibition of discoidin domain receptors by imatinib prevented pancreatic fibrosis demonstrated in experimental chronic pancreatitis model. Sci Rep. 2021;11:12894 pubmed publisher
  3. Chae S, Hong J, Kang K, Shin A, Kim D, Lee S, et al. Molecular laterality encodes stress susceptibility in the medial prefrontal cortex. Mol Brain. 2021;14:92 pubmed publisher
  4. Wu X, Shu L, Zhang Z, Li J, Zong J, Cheong L, et al. Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells. Adv Sci (Weinh). 2021;8:e2003721 pubmed publisher
  5. Tamura T, Kodama T, Sato K, Murai K, Yoshioka T, Shigekawa M, et al. Dysregulation of PI3K and Hippo signaling pathways synergistically induces chronic pancreatitis via CTGF upregulation. J Clin Invest. 2021;131: pubmed publisher
  6. Tsutsui K, Machida H, Nakagawa A, Ahn K, Morita R, Sekiguchi K, et al. Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions. Nat Commun. 2021;12:2577 pubmed publisher
  7. Lyu L, Chen J, Wang W, Yan T, Lin J, Gao H, et al. Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress. J Cell Mol Med. 2021;25:3136-3148 pubmed publisher
  8. Sharma N, Hans C. Interleukin 12p40 Deficiency Promotes Abdominal Aortic Aneurysm by Activating CCN2/MMP2 Pathways. J Am Heart Assoc. 2021;10:e017633 pubmed publisher
  9. Hao Q, Zong X, Sun Q, Lin Y, Song Y, Hashemikhabir S, et al. The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway. elife. 2020;9: pubmed publisher
  10. Stojanović S, Fuchs M, Fiedler J, Xiao K, Meinecke A, Just A, et al. Comprehensive Bioinformatics Identifies Key microRNA Players in ATG7-Deficient Lung Fibroblasts. Int J Mol Sci. 2020;21: pubmed publisher
  11. Jin D, Guo J, Wu Y, Yang L, Wang X, Du J, et al. m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2-mediated YAP activity in NSCLC. Mol Cancer. 2020;19:40 pubmed publisher
  12. Guo X, Kolpakov M, Hooshdaran B, Schappell W, Wang T, Eguchi S, et al. Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload. JACC Basic Transl Sci. 2020;5:69-83 pubmed publisher
  13. An S, Raju I, Surenkhuu B, Kwon J, Gulati S, Karaman M, et al. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Ocul Surf. 2019;: pubmed publisher
  14. Lin P, Wu M, Qin J, Yang J, Ye C, Wang C. Magnesium lithospermate B improves renal hemodynamics and reduces renal oxygen consumption in 5/6th renal ablation/infarction rats. BMC Nephrol. 2019;20:49 pubmed publisher
  15. Moro A, Driscoll T, Boraas L, Armero W, Kasper D, Baeyens N, et al. MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nat Cell Biol. 2019;21:348-358 pubmed publisher
  16. Ho L, Skiba N, Ullmer C, Rao P. Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2018;59:1969-1984 pubmed publisher
  17. Chowdhury A, Hasselbach L, Echtermeyer F, Jyotsana N, Theilmeier G, Herzog C. Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts. Sci Rep. 2017;7:42725 pubmed publisher
  18. Mindos T, Dun X, North K, Doddrell R, Schulz A, Edwards P, et al. Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity. J Cell Biol. 2017;216:495-510 pubmed publisher
  19. Jin X, Wu N, Dai J, Li Q, Xiao X. TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4-phenylbutyrate treatment. Cancer Med. 2017;6:424-438 pubmed publisher
  20. Wang L, Luo J, Li B, Tian X, Chen L, Huang Y, et al. Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow. Nature. 2016;540:579-582 pubmed publisher
  21. Kim H, Kim M, Park Y, Park I, Kim T, Yang S, et al. Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice. Gastroenterology. 2017;152:616-630 pubmed publisher
  22. Che D, Zhou T, Lan Y, Xie J, Gong H, Li C, et al. High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells. Int J Mol Med. 2016;38:1815-1822 pubmed publisher
  23. Matkar P, Singh K, Rudenko D, Kim Y, Kuliszewski M, Prud homme G, et al. Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:69489-69506 pubmed publisher
  24. Simile M, Latte G, Demartis M, Brozzetti S, Calvisi D, Porcu A, et al. Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease. Oncotarget. 2016;7:49194-49216 pubmed publisher
  25. Li C, Zhen G, Chai Y, Xie L, Crane J, Farber E, et al. RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix. Nat Commun. 2016;7:11455 pubmed publisher
  26. Niu H, Liu I, Niu C, Ku P, Hsu C, Cheng J. Eucommia bark (Du-Zhong) improves diabetic nephropathy without altering blood glucose in type 1-like diabetic rats. Drug Des Devel Ther. 2016;10:971-8 pubmed publisher
  27. Lim T, Lee I, Kim J, Kang W. Synergistic Effect of Simvastatin Plus Radiation in Gastric Cancer and Colorectal Cancer: Implications of BIRC5 and Connective Tissue Growth Factor. Int J Radiat Oncol Biol Phys. 2015;93:316-25 pubmed publisher
  28. Sereno J, Nunes S, Rodrigues Santos P, Vala H, Rocha Pereira P, Fernandes J, et al. Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers. Biomed Res Int. 2014;2014:576929 pubmed publisher