This is a Validated Antibody Database (VAD) review about rat Cbl, based on 16 published articles (read how Labome selects the articles), using Cbl antibody in all methods. It is aimed to help Labome visitors find the most suited Cbl antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cbl synonym: RGD1561386; c-Cbl

Knockout validation
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot knockout validation; mouse; fig 6
Cell Signaling Technology Cbl antibody (Cell Signaling Tech, 2747) was used in western blot knockout validation on mouse samples (fig 6). Mol Syst Biol (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-9)
  • western blot; human; loading ...; fig 4g
Santa Cruz Biotechnology Cbl antibody (Santa Cruz, sc-1651) was used in western blot on human samples (fig 4g). Theranostics (2021) ncbi
mouse monoclonal (C-3)
  • immunocytochemistry; human; loading ...; fig 5d
  • western blot; human; loading ...; fig 5a
Santa Cruz Biotechnology Cbl antibody (Santa Cruz Biotechnology, Sc-393543) was used in immunocytochemistry on human samples (fig 5d) and in western blot on human samples (fig 5a). PLoS Pathog (2016) ncbi
mouse monoclonal
  • western blot; mouse; loading ...; fig 2a
Santa Cruz Biotechnology Cbl antibody (Santa Cruz Biotechnology, Inc., sc-377571) was used in western blot on mouse samples (fig 2a). J Exp Med (2016) ncbi
mouse monoclonal (A-9)
  • western blot; human
Santa Cruz Biotechnology Cbl antibody (Santa Cruz Biotechnology, sc-1651) was used in western blot on human samples . J Biol Chem (2015) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6c
Cell Signaling Technology Cbl antibody (Cell Signaling, 2747) was used in western blot on mouse samples (fig 6c). Sci Signal (2018) ncbi
domestic rabbit monoclonal (D4E10)
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 2a
Cell Signaling Technology Cbl antibody (Cell Signaling Technology, 8447) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 2a). mSphere (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b
In order to propose that casitas B-cell lymphoma family proteins protect mammary epithelial cells from proteotoxic stress-induced cell death by promoting turnover of active c-Src, Cell Signaling Technology Cbl antibody (Cell Singaling, 2747) was used in western blot on mouse samples (fig 1b). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; fig 6
Cell Signaling Technology Cbl antibody (Cell Signaling Tech, 2747) was used in western blot knockout validation on mouse samples (fig 6). Mol Syst Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 7
Cell Signaling Technology Cbl antibody (Cell Signaling, 2747) was used in western blot on human samples (fig 7). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...
In order to study Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB and tyrosine kinase inhibitors in murine cells, Cell Signaling Technology Cbl antibody (Cell Signaling, 2747) was used in western blot on mouse samples . Exp Hematol (2016) ncbi
BD Biosciences
mouse monoclonal (17/c-Cbl)
  • western blot; rat; loading ...; fig 2d
BD Biosciences Cbl antibody (BD Bioscences, 610441) was used in western blot on rat samples (fig 2d). Cell (2019) ncbi
mouse monoclonal (17/c-Cbl)
  • immunocytochemistry; human; fig s12
In order to develop a new multiplex dSTORM imaging strategy to localize epitopes on activated T-cells, BD Biosciences Cbl antibody (BD Biosciences, 610442) was used in immunocytochemistry on human samples (fig s12). Mol Biol Cell (2016) ncbi
mouse monoclonal (17/c-Cbl)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, BD Biosciences Cbl antibody (BD, 17) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (17/c-Cbl)
  • immunocytochemistry; human; fig s10
BD Biosciences Cbl antibody (BD Bioscience, 610442) was used in immunocytochemistry on human samples (fig s10). Nat Commun (2015) ncbi
mouse monoclonal (17/c-Cbl)
  • western blot; human; fig 5
BD Biosciences Cbl antibody (BD transduction, 610441) was used in western blot on human samples (fig 5). J Cell Sci (2015) ncbi
mouse monoclonal (17/c-Cbl)
  • western blot; human; fig 4
BD Biosciences Cbl antibody (BD Biosciences, 610441) was used in western blot on human samples (fig 4). Carcinogenesis (2014) ncbi
Articles Reviewed
  1. Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, et al. DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells. Theranostics. 2021;11:6355-6369 pubmed publisher
  2. Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed publisher
  3. Roy N, MacKay J, Robertson T, Hammer D, Burkhardt J. Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1. Sci Signal. 2018;11: pubmed publisher
  4. Cen O, Kannan K, Huck Sappal J, Yu J, Zhang M, Arikan M, et al. Spleen Tyrosine Kinase Inhibitor TAK-659 Prevents Splenomegaly and Tumor Development in a Murine Model of Epstein-Barr Virus-Associated Lymphoma. mSphere. 2018;3: pubmed publisher
  5. Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed publisher
  6. Kumar B, Dutta D, Iqbal J, Ansari M, Roy A, Chikoti L, et al. ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus. PLoS Pathog. 2016;12:e1005960 pubmed publisher
  7. Yi J, Manna A, Barr V, Hong J, Neuman K, Samelson L. madSTORM: a superresolution technique for large-scale multiplexing at single-molecule accuracy. Mol Biol Cell. 2016;27:3591-3600 pubmed
  8. Voisinne G, García Blesa A, Chaoui K, Fiore F, Bergot E, Girard L, et al. Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation. Mol Syst Biol. 2016;12:876 pubmed publisher
  9. Zhu L, Luo T, Xu X, Guo Y, Zhao X, Wang T, et al. E3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor-mediated antifungal innate immunity. J Exp Med. 2016;213:1555-70 pubmed publisher
  10. Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed publisher
  11. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  12. Ishibashi T, Yaguchi A, Terada K, Ueno Yokohata H, Tomita O, Iijima K, et al. Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells. Exp Hematol. 2016;44:177-88.e5 pubmed publisher
  13. Rouka E, Simister P, Janning M, Kumbrink J, Konstantinou T, Muniz J, et al. Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3). J Biol Chem. 2015;290:25275-92 pubmed publisher
  14. Capuani F, Conte A, Argenzio E, Marchetti L, Priami C, Polo S, et al. Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells. Nat Commun. 2015;6:7999 pubmed publisher
  15. Diesenberg K, Beerbaum M, Fink U, Schmieder P, Krauss M. SEPT9 negatively regulates ubiquitin-dependent downregulation of EGFR. J Cell Sci. 2015;128:397-407 pubmed publisher
  16. Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, et al. Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility. Carcinogenesis. 2014;35:1901-10 pubmed publisher