This is a Validated Antibody Database (VAD) review about rat Casp1, based on 31 published articles (read how Labome selects the articles), using Casp1 antibody in all methods. It is aimed to help Labome visitors find the most suited Casp1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Casp1 synonym: Ice; Il1bc

Santa Cruz Biotechnology
mouse monoclonal (14F468)
  • western blot; mouse; 1:500; loading ...; fig 7e
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz Biotechnology, sc-56036) was used in western blot on mouse samples at 1:500 (fig 7e). Oxid Med Cell Longev (2021) ncbi
mouse monoclonal (14F468)
  • western blot; rat; 1:1000; loading ...; fig 6c
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, Sc56036) was used in western blot on rat samples at 1:1000 (fig 6c). Front Physiol (2021) ncbi
mouse monoclonal (14F468)
  • western blot; rat; 1:1000; loading ...; fig 2a
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, sc-56036) was used in western blot on rat samples at 1:1000 (fig 2a). J Cardiovasc Pharmacol (2021) ncbi
mouse monoclonal (14F468)
  • western blot; mouse; 1:200; loading ...; fig 2a
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz Biotechnology, sc-56036) was used in western blot on mouse samples at 1:200 (fig 2a). Mol Med Rep (2021) ncbi
mouse monoclonal (14F468)
  • western blot; mouse; 1:3000; loading ...; fig 6c
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, sc-56036) was used in western blot on mouse samples at 1:3000 (fig 6c). Sci Adv (2020) ncbi
mouse monoclonal (14F468)
  • western blot; human; loading ...; fig 3d
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, 14F468) was used in western blot on human samples (fig 3d). Nat Immunol (2019) ncbi
mouse monoclonal (14F468)
  • immunohistochemistry; mouse; 1 ug/ml; loading ...; fig 3b
In order to test if alkali-injured corneal epithelia activate innate immunity through the nucleotide-binding oligomerization domain-containing protein-like receptor family pyrin domain containing 3 inflammasome pathway, Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, SC-56036) was used in immunohistochemistry on mouse samples at 1 ug/ml (fig 3b). Int J Mol Sci (2017) ncbi
mouse monoclonal (14F468)
  • western blot; mouse; 1:200; fig 3
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, sc-56036) was used in western blot on mouse samples at 1:200 (fig 3). Int J Mol Sci (2016) ncbi
mouse monoclonal (14F468)
  • western blot; mouse; fig 2
In order to analyze regulation of NLRP3 inflammasome in adipose tissue by phosphodiesterase 3B (PDE3B), Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, SC-56036) was used in western blot on mouse samples (fig 2). Sci Rep (2016) ncbi
mouse monoclonal
  • western blot; mouse; fig 1d
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz Biotechnology, sc-392736) was used in western blot on mouse samples (fig 1d). Int J Mol Med (2016) ncbi
mouse monoclonal (14F468)
  • western blot; mouse; fig 6
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz Biotechnology, sc-C56036) was used in western blot on mouse samples (fig 6). PLoS ONE (2015) ncbi
mouse monoclonal (14F468)
  • western blot; human; 1:1000; fig 2c
  • immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig 8
  • western blot; mouse; 1:1000; fig 2c
Santa Cruz Biotechnology Casp1 antibody (Santa-Cruz biotechnology, sc-56036) was used in western blot on human samples at 1:1000 (fig 2c), in immunohistochemistry - paraffin section on mouse samples at 1:2000 (fig 8) and in western blot on mouse samples at 1:1000 (fig 2c). PLoS ONE (2015) ncbi
mouse monoclonal (14F468)
  • western blot; mouse; fig 5b
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, sc-56036) was used in western blot on mouse samples (fig 5b). Front Microbiol (2015) ncbi
mouse monoclonal (14F468)
  • western blot; human; 1:1000; loading ...; fig 3a
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, sc-56036) was used in western blot on human samples at 1:1000 (fig 3a). J Biol Chem (2015) ncbi
mouse monoclonal (14F468)
  • western blot; mouse
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz Biotechnology, sc-56036) was used in western blot on mouse samples . Cell Res (2015) ncbi
mouse monoclonal (14F468)
  • western blot; mouse; fig 2
  • western blot; human; fig 2
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz Biotechnology, sc-56036) was used in western blot on mouse samples (fig 2) and in western blot on human samples (fig 2). Immunology (2015) ncbi
mouse monoclonal (14F468)
  • western blot; mouse; fig 5
In order to study the effects of aged garlic extract and its FruArg component by proteomic analysis and lipopolysaccharide-induced neuroinflammatory response in microglial cells, Santa Cruz Biotechnology Casp1 antibody (Santa Cruz Biotechnology, SC-56036) was used in western blot on mouse samples (fig 5). PLoS ONE (2014) ncbi
mouse monoclonal (14F468)
  • western blot; rat; 1:1000
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz Biotechnology, sc-56036) was used in western blot on rat samples at 1:1000. World J Biol Chem (2014) ncbi
mouse monoclonal (14F468)
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology Casp1 antibody (SantaCruz, sc-56036) was used in western blot on human samples (fig 3a). Front Cell Neurosci (2014) ncbi
mouse monoclonal (14F468)
  • western blot; human
Santa Cruz Biotechnology Casp1 antibody (Santa Cruz, sc-56036) was used in western blot on human samples . Infect Immun (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR16883)
  • western blot; human; 1:1000; loading ...; fig 2a
Abcam Casp1 antibody (Abcam, ab179515) was used in western blot on human samples at 1:1000 (fig 2a). Aging (Albany NY) (2021) ncbi
domestic rabbit monoclonal (EPR16883)
  • western blot; human; loading ...; fig 3f
Abcam Casp1 antibody (Abcam, ab179515) was used in western blot on human samples (fig 3f). Science (2021) ncbi
domestic rabbit monoclonal (EPR16883)
  • western blot; mouse; 1:1000; loading ...; fig 3c
Abcam Casp1 antibody (Abcam, ab179515) was used in western blot on mouse samples at 1:1000 (fig 3c). elife (2020) ncbi
domestic rabbit monoclonal (EPR16883)
  • western blot; mouse; 1:1000; loading ...; fig 7a, 7b
Abcam Casp1 antibody (Abcam, ab179515) was used in western blot on mouse samples at 1:1000 (fig 7a, 7b). Theranostics (2020) ncbi
domestic rabbit monoclonal (EPR16883)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 8
  • western blot; mouse; 1:1000; loading ...; fig 7a
Abcam Casp1 antibody (Abcam, ab179515) was used in immunohistochemistry on mouse samples at 1:200 (fig 8) and in western blot on mouse samples at 1:1000 (fig 7a). J Transl Med (2020) ncbi
domestic rabbit monoclonal (EPR16883)
  • western blot; rat; 1:1000; loading ...; fig 8d
Abcam Casp1 antibody (Abcam, ab179515) was used in western blot on rat samples at 1:1000 (fig 8d). Front Neurosci (2019) ncbi
domestic rabbit monoclonal (EPR16883)
  • western blot; rat; loading ...; fig 4a
Abcam Casp1 antibody (Abcam, ab179515) was used in western blot on rat samples (fig 4a). Biomed Pharmacother (2019) ncbi
domestic rabbit monoclonal (EPR16883)
  • western blot; rat; fig 4a
Abcam Casp1 antibody (abcam, ab179515) was used in western blot on rat samples (fig 4a). Biochem Biophys Res Commun (2018) ncbi
Novus Biologicals
domestic rabbit polyclonal (13A9)
  • western blot; mouse; 1:100; loading ...; fig 6a
Novus Biologicals Casp1 antibody (Novus, NBP1-45433) was used in western blot on mouse samples at 1:100 (fig 6a). Infect Immun (2020) ncbi
domestic rabbit polyclonal (13A9)
  • western blot; rat; 1:500; loading ...; fig 7a
Novus Biologicals Casp1 antibody (NOVUS, NBP1-45433) was used in western blot on rat samples at 1:500 (fig 7a). Oxid Med Cell Longev (2020) ncbi
domestic rabbit polyclonal (13A9)
  • western blot; rat; 1:500; loading ...; fig 5c
Novus Biologicals Casp1 antibody (NOVUS, NBP1-45433) was used in western blot on rat samples at 1:500 (fig 5c). Stroke (2018) ncbi
Articles Reviewed
  1. Cheng Q, Ding H, Fang J, Fang X, Liu H, Wang J, et al. Aquaporin 9 Represents a Novel Target of Chronic Liver Injury That May Antagonize Its Progression by Reducing Lipotoxicity. Oxid Med Cell Longev. 2021;2021:5653700 pubmed publisher
  2. Albino A, Zambom F, Foresto Neto O, Oliveira K, Ávila V, Arias S, et al. Renal Inflammation and Innate Immune Activation Underlie the Transition From Gentamicin-Induced Acute Kidney Injury to Renal Fibrosis. Front Physiol. 2021;12:606392 pubmed publisher
  3. Lee C, Chen W, Chen S, Lee T. Taurine Alleviates Sympathetic Innervation by Inhibiting NLRP3 Inflammasome in Postinfarcted Rats. J Cardiovasc Pharmacol. 2021;77:745-755 pubmed publisher
  4. Su Y, Wang Y, Liu M, Chen H. Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition. Mol Med Rep. 2021;24: pubmed publisher
  5. Zhao Z, Wang X, Zhang R, Ma B, Niu S, Di X, et al. Melatonin attenuates smoking-induced atherosclerosis by activating the Nrf2 pathway via NLRP3 inflammasomes in endothelial cells. Aging (Albany NY). 2021;13:11363-11380 pubmed publisher
  6. Wang Q, Gao H, Clark K, Mugisha C, Davis K, Tang J, et al. CARD8 is an inflammasome sensor for HIV-1 protease activity. Science. 2021;371: pubmed publisher
  7. Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv. 2020;6: pubmed publisher
  8. Green J, Swanton T, Morris L, El Sharkawy L, Cook J, Yu S, et al. LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation. elife. 2020;9: pubmed publisher
  9. Hu J, Wang H, Li X, Liu Y, Mi Y, Kong H, et al. Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder. Theranostics. 2020;10:9702-9720 pubmed publisher
  10. Gao Y, Dai X, Li Y, Li G, Lin X, Ai C, et al. Role of Parkin-mediated mitophagy in the protective effect of polydatin in sepsis-induced acute kidney injury. J Transl Med. 2020;18:114 pubmed publisher
  11. Zhuang K, Zuo Y, Sherchan P, Wang J, Yan X, Liu F. Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats. Front Neurosci. 2019;13:1441 pubmed publisher
  12. Rumfield C, Hyseni I, McBride J, Walker D, Fang R. Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection. Infect Immun. 2020;88: pubmed publisher
  13. Yu J, Wang W, Matei N, Li X, Pang J, Mo J, et al. Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats. Oxid Med Cell Longev. 2020;2020:4717258 pubmed publisher
  14. Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, et al. Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma. Biomed Pharmacother. 2019;118:109188 pubmed publisher
  15. Choi Y, Kim S, Choi Y, Nielsen T, Yan J, Lu A, et al. SERPINB1-mediated checkpoint of inflammatory caspase activation. Nat Immunol. 2019;20:276-287 pubmed publisher
  16. Zhou K, Enkhjargal B, Xie Z, Sun C, Wu L, Malaguit J, et al. Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat. Stroke. 2018;49:175-183 pubmed publisher
  17. Unuma K, Aki T, Nagano S, Watanabe R, Uemura K. The down-regulation of cardiac contractile proteins underlies myocardial depression during sepsis and is mitigated by carbon monoxide. Biochem Biophys Res Commun. 2018;495:1668-1674 pubmed publisher
  18. Bian F, Xiao Y, Zaheer M, Volpe E, Pflugfelder S, Li D, et al. Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn. Int J Mol Sci. 2017;18: pubmed publisher
  19. Zhou L, Zheng Y, Li Z, Bao L, Dou Y, Tang Y, et al. Compound K Attenuates the Development of Atherosclerosis in ApoE(-/-) Mice via LXR? Activation. Int J Mol Sci. 2016;17: pubmed publisher
  20. Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed publisher
  21. Wu M, Ai W, Chen L, Zhao S, Liu E. Bradykinin receptors and EphB2/EphrinB2 pathway in response to high glucose-induced osteoblast dysfunction and hyperglycemia-induced bone deterioration in mice. Int J Mol Med. 2016;37:565-74 pubmed publisher
  22. Yao X, Carlson D, Sun Y, Ma L, Wolf S, Minei J, et al. Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. PLoS ONE. 2015;10:e0139416 pubmed publisher
  23. Shipkowski K, Taylor A, Thompson E, Glista Baker E, Sayers B, Messenger Z, et al. An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1. PLoS ONE. 2015;10:e0128888 pubmed publisher
  24. Song L, Huang Y, Zhao M, Wang Z, Wang S, Sun H, et al. A critical role for hemolysin in Vibrio fluvialis-induced IL-1β secretion mediated by the NLRP3 inflammasome in macrophages. Front Microbiol. 2015;6:510 pubmed publisher
  25. Callaway J, Smith S, McKinnon K, de Silva A, Crowe J, Ting J. Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection. J Biol Chem. 2015;290:17306-20 pubmed publisher
  26. Wang H, Hong L, Huang J, Jiang Q, Tao R, Tan C, et al. P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy. Cell Res. 2015;25:674-90 pubmed publisher
  27. Cheng Y, Song L, Huang Y, Xiong Y, Zhang X, Sun H, et al. Effect of enterohaemorrhagic Escherichia coli O157:H7-specific enterohaemolysin on interleukin-1β production differs between human and mouse macrophages due to the different sensitivity of NLRP3 activation. Immunology. 2015;145:258-67 pubmed publisher
  28. Zhou H, Qu Z, Mossine V, Nknolise D, Li J, Chen Z, et al. Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells. PLoS ONE. 2014;9:e113531 pubmed publisher
  29. Dirks Naylor A, Kouzi S, Bero J, Tran N, Yang S, Mabolo R. Effects of acute doxorubicin treatment on hepatic proteome lysine acetylation status and the apoptotic environment. World J Biol Chem. 2014;5:377-86 pubmed publisher
  30. Sutinen E, Korolainen M, Häyrinen J, Alafuzoff I, Petratos S, Salminen A, et al. Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells. Front Cell Neurosci. 2014;8:214 pubmed publisher
  31. Park E, Na H, Song Y, Shin S, Kim Y, Chung J. Activation of NLRP3 and AIM2 inflammasomes by Porphyromonas gingivalis infection. Infect Immun. 2014;82:112-23 pubmed publisher