This is a Validated Antibody Database (VAD) review about rat Brd2, based on 11 published articles (read how Labome selects the articles), using Brd2 antibody in all methods. It is aimed to help Labome visitors find the most suited Brd2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Brd2 synonym: Ring3

Cell Signaling Technology
domestic rabbit monoclonal (D89B4)
  • ChIP-Seq; human; loading ...; fig s12c
Cell Signaling Technology Brd2 antibody (Cell Signalling, 5848S) was used in ChIP-Seq on human samples (fig s12c). Science (2020) ncbi
domestic rabbit monoclonal (D89B4)
  • western blot; human; fig 7f
Cell Signaling Technology Brd2 antibody (Cell Signaling, 5848) was used in western blot on human samples (fig 7f). Cancer Cell (2019) ncbi
domestic rabbit monoclonal (D89B4)
  • western blot; human; loading ...; fig s5b
Cell Signaling Technology Brd2 antibody (Cell Signalling, D89B4) was used in western blot on human samples (fig s5b). Science (2017) ncbi
domestic rabbit monoclonal (D89B4)
  • western blot; human; loading ...; fig s3d
Cell Signaling Technology Brd2 antibody (CST, 5848) was used in western blot on human samples (fig s3d). Proc Natl Acad Sci U S A (2017) ncbi
domestic rabbit monoclonal (D89B4)
  • western blot; human; fig 2
Cell Signaling Technology Brd2 antibody (Cell Signaling, 5848) was used in western blot on human samples (fig 2). Proc Natl Acad Sci U S A (2016) ncbi
domestic rabbit monoclonal (D89B4)
  • immunohistochemistry; human; 1:100; fig s2
Cell Signaling Technology Brd2 antibody (Cell Signalling Technology, 5848) was used in immunohistochemistry on human samples at 1:100 (fig s2). Mol Cancer Ther (2016) ncbi
domestic rabbit monoclonal (D89B4)
  • western blot; human; 1:1000; fig 3h
Cell Signaling Technology Brd2 antibody (Cell Signaling Technology, 5848) was used in western blot on human samples at 1:1000 (fig 3h). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D89B4)
  • western blot; human; 1:500; fig 6
Cell Signaling Technology Brd2 antibody (Cell Signaling, 5848) was used in western blot on human samples at 1:500 (fig 6). Nature (2015) ncbi
domestic rabbit monoclonal (D89B4)
  • western blot; mouse; 1:1000; fig 1a
In order to report that an inhibitor of the bromodomain and extraterminal family of proteins suppresses pancreatic ductal adenocarcinoma, Cell Signaling Technology Brd2 antibody (Cell Signaling Technology, 5848) was used in western blot on mouse samples at 1:1000 (fig 1a). Nat Med (2015) ncbi
domestic rabbit monoclonal (D89B4)
  • chromatin immunoprecipitation; human; fig 8
Cell Signaling Technology Brd2 antibody (Cell Signaling Tech, 5848) was used in chromatin immunoprecipitation on human samples (fig 8). Nucleic Acids Res (2015) ncbi
domestic rabbit monoclonal (D89B4)
  • ChIP-Seq; human
Cell Signaling Technology Brd2 antibody (Cell signaling, 5848) was used in ChIP-Seq on human samples . Nat Biotechnol (2014) ncbi
Articles Reviewed
  1. Gilan O, Rioja I, Knezevic K, Bell M, Yeung M, Harker N, et al. Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation. Science. 2020;368:387-394 pubmed publisher
  2. Sin Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019;36:51-67.e7 pubmed publisher
  3. Tyler D, Vappiani J, Cañeque T, Lam E, Ward A, Gilan O, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017;356:1397-1401 pubmed publisher
  4. Sherman M, Yu R, Tseng T, Sousa C, Liu S, Truitt M, et al. Stromal cues regulate the pancreatic cancer epigenome and metabolome. Proc Natl Acad Sci U S A. 2017;114:1129-1134 pubmed publisher
  5. Raina K, Lu J, Qian Y, Altieri M, Gordon D, Rossi A, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016;113:7124-9 pubmed publisher
  6. Tögel L, Nightingale R, Chueh A, Jayachandran A, Tran H, Phesse T, et al. Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Mol Cancer Ther. 2016;15:1217-26 pubmed publisher
  7. Shao Z, Zhang R, Khodadadi Jamayran A, Chen B, Crowley M, Festok M, et al. The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun. 2016;7:10869 pubmed publisher
  8. Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  9. Mazur P, Herner A, Mello S, Wirth M, Hausmann S, Sánchez Rivera F, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med. 2015;21:1163-71 pubmed publisher
  10. Chan S, Selth L, Li Y, Nyquist M, Miao L, Bradner J, et al. Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies. Nucleic Acids Res. 2015;43:5880-97 pubmed publisher
  11. Anders L, Guenther M, Qi J, Fan Z, Marineau J, Rahl P, et al. Genome-wide localization of small molecules. Nat Biotechnol. 2014;32:92-6 pubmed publisher