This is a Validated Antibody Database (VAD) review about rat Bnip3, based on 32 published articles (read how Labome selects the articles), using Bnip3 antibody in all methods. It is aimed to help Labome visitors find the most suited Bnip3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
mouse monoclonal (ANa40)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3a
Abcam Bnip3 antibody (Abcam, Ab10433) was used in immunohistochemistry knockout validation on mouse samples (fig 3a). Cell Death Dis (2019) ncbi
Abcam
mouse monoclonal (ANa40)
  • western blot; rat; fig 7f
Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on rat samples (fig 7f). Oxid Med Cell Longev (2021) ncbi
mouse monoclonal (ANa40)
  • western blot; mouse; 1:1000; fig 5i
Abcam Bnip3 antibody (Abcam, Ab10433) was used in western blot on mouse samples at 1:1000 (fig 5i). BMC Biol (2021) ncbi
domestic rabbit monoclonal (EPR4034)
  • western blot; mouse; 1:1000; loading ...
Abcam Bnip3 antibody (Abcam, EPR4034) was used in western blot on mouse samples at 1:1000. elife (2020) ncbi
mouse monoclonal (ANa40)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3a
Abcam Bnip3 antibody (Abcam, Ab10433) was used in immunohistochemistry knockout validation on mouse samples (fig 3a). Cell Death Dis (2019) ncbi
domestic rabbit monoclonal (EPR4034)
  • western blot; mouse; loading ...; fig 1a
Abcam Bnip3 antibody (Abcam, ab109362) was used in western blot on mouse samples (fig 1a). Cell Death Dis (2019) ncbi
mouse monoclonal (ANa40)
  • western blot; mouse; 1:800; loading ...; fig 6b
Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on mouse samples at 1:800 (fig 6b). J Clin Invest (2019) ncbi
domestic rabbit monoclonal (EPR4034)
  • western blot; mouse; loading ...; fig 5d
Abcam Bnip3 antibody (Abcam, ab109362) was used in western blot on mouse samples (fig 5d). Cell Death Dis (2018) ncbi
domestic rabbit monoclonal (EPR4034)
  • western blot; human; loading ...; fig 2a
Abcam Bnip3 antibody (Abcam, ab109362) was used in western blot on human samples (fig 2a). Sci Rep (2017) ncbi
domestic rabbit monoclonal (EPR4034)
  • western blot; rat; 1:1000; loading ...
  • western blot; mouse; 1:1000; loading ...
In order to explore how the relationship between OPA1 and BNIP3 impacts dominant optic atrophy pathogenesis, Abcam Bnip3 antibody (Abcam, ab109362) was used in western blot on rat samples at 1:1000 and in western blot on mouse samples at 1:1000. J Neurochem (2017) ncbi
mouse monoclonal (ANa40)
  • immunohistochemistry; human; loading ...; fig s4a
  • western blot; human; loading ...; fig 4a
In order to study mitochondrial biogenesis and mitophagy in cancer cells, Abcam Bnip3 antibody (Abcam, ab10433) was used in immunohistochemistry on human samples (fig s4a) and in western blot on human samples (fig 4a). Oxid Med Cell Longev (2016) ncbi
mouse monoclonal (ANa40)
  • western blot; human; 1:1000; fig 1
Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples at 1:1000 (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (ANa40)
  • western blot; human; fig 13
Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples (fig 13). PLoS ONE (2016) ncbi
mouse monoclonal (ANa40)
  • western blot; human; loading ...; fig 2a
Abcam Bnip3 antibody (Abcam, ANa40) was used in western blot on human samples (fig 2a). Oncogenesis (2016) ncbi
mouse monoclonal (ANa40)
  • western blot; human; 1:2000; fig 4
In order to investigate factors that control PHD1 activity, Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples at 1:2000 (fig 4). J Cell Sci (2016) ncbi
mouse monoclonal (ANa40)
  • western blot; human; loading ...; fig 3d
Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples (fig 3d). Oncotarget (2015) ncbi
mouse monoclonal (ANa40)
  • western blot; human; 1:1000; fig 9
Abcam Bnip3 antibody (abcam, ab10433) was used in western blot on human samples at 1:1000 (fig 9). Sci Rep (2015) ncbi
mouse monoclonal (ANa40)
  • western blot; human; fig 1c
In order to report that expression of HIF2alpha is regulated by the deubiquitylase Cezanne in an E2F1-dependent manner, Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples (fig 1c). J Cell Sci (2015) ncbi
mouse monoclonal (ANa40)
  • western blot; mouse; 1:250; loading ...; fig 5a, 5b
Abcam Bnip3 antibody (Abcam, 10433) was used in western blot on mouse samples at 1:250 (fig 5a, 5b). EMBO Mol Med (2015) ncbi
mouse monoclonal (ANa40)
  • immunohistochemistry - frozen section; mouse; 1:200
  • western blot; mouse
Abcam Bnip3 antibody (Abcam, Ab10433) was used in immunohistochemistry - frozen section on mouse samples at 1:200 and in western blot on mouse samples . PLoS ONE (2014) ncbi
domestic rabbit monoclonal (EPR4034)
  • immunocytochemistry; human; fig 2
Abcam Bnip3 antibody (Epitomics, 3485-1) was used in immunocytochemistry on human samples (fig 2). Nat Chem Biol (2014) ncbi
mouse monoclonal (ANa40)
  • western blot; mouse
Abcam Bnip3 antibody (Abcam, Ab10433) was used in western blot on mouse samples . Am J Pathol (2013) ncbi
mouse monoclonal (ANa40)
  • western blot; human; fig 8
Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples (fig 8). Cell Cycle (2013) ncbi
mouse monoclonal (ANa40)
  • western blot; human
Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples . Cell Cycle (2013) ncbi
mouse monoclonal (ANa40)
  • immunocytochemistry; human
  • western blot; human
Abcam Bnip3 antibody (Abcam, ab10433) was used in immunocytochemistry on human samples and in western blot on human samples . Cell Cycle (2013) ncbi
mouse monoclonal (ANa40)
  • western blot; human; fig 2b
In order to study the inhibition of tumor growth caused by mitochondrial dysfunction in the epithelial cancer cell compartment, Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples (fig 2b). Cell Cycle (2013) ncbi
mouse monoclonal (ANa40)
  • western blot; human; fig s5
Abcam Bnip3 antibody (Abcam, ab10433) was used in western blot on human samples (fig s5). Biosci Rep (2013) ncbi
mouse monoclonal (ANa40)
  • immunocytochemistry; human
  • western blot; human
Abcam Bnip3 antibody (Abcam, ab10433) was used in immunocytochemistry on human samples and in western blot on human samples . Cell Cycle (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (ANa40)
  • western blot; mouse; 1:1000; loading ...; fig 3b
Santa Cruz Biotechnology Bnip3 antibody (Santa Cruz Biotechnology, sc-56167) was used in western blot on mouse samples at 1:1000 (fig 3b). Nat Commun (2021) ncbi
mouse monoclonal (ANa40)
  • western blot; human; fig 4
Santa Cruz Biotechnology Bnip3 antibody (Santa Cruz, Sc-56167) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
mouse monoclonal (ANa40)
  • western blot; human; fig 7
  • western blot; mouse; fig 7
Santa Cruz Biotechnology Bnip3 antibody (santa Cruz, sc-56167) was used in western blot on human samples (fig 7) and in western blot on mouse samples (fig 7). Autophagy (2015) ncbi
mouse monoclonal (ANa40)
  • western blot; human; fig 3
In order to investigate MAPK14-driven metabolic reprogramming, Santa Cruz Biotechnology Bnip3 antibody (Santa Cruz, sc-56167) was used in western blot on human samples (fig 3). Autophagy (2014) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s13g
Cell Signaling Technology Bnip3 antibody (CST, 3769S) was used in western blot on mouse samples (fig s13g). Science (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 6a
Cell Signaling Technology Bnip3 antibody (Cell Signaling, 3769) was used in western blot on human samples at 1:500 (fig 6a). Autophagy (2016) ncbi
Articles Reviewed
  1. Huo S, Shi W, Ma H, Yan D, Luo P, Guo J, et al. Alleviation of Inflammation and Oxidative Stress in Pressure Overload-Induced Cardiac Remodeling and Heart Failure via IL-6/STAT3 Inhibition by Raloxifene. Oxid Med Cell Longev. 2021;2021:6699054 pubmed publisher
  2. Affortit C, Casas F, Ladrech S, Ceccato J, Bourien J, Coyat C, et al. Exacerbated age-related hearing loss in mice lacking the p43 mitochondrial T3 receptor. BMC Biol. 2021;19:18 pubmed publisher
  3. Choi G, Lee H, Chae C, Cho J, Jung Y, Kim J, et al. BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects. Nat Commun. 2021;12:487 pubmed publisher
  4. Alexander R, Liou Y, Knudsen N, Starost K, Xu C, Hyde A, et al. Bmal1 integrates mitochondrial metabolism and macrophage activation. elife. 2020;9: pubmed publisher
  5. Moya I, Castaldo S, Van den Mooter L, Soheily S, Sansores Garcia L, Jacobs J, et al. Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice. Science. 2019;366:1029-1034 pubmed publisher
  6. Tang C, Han H, Liu Z, Liu Y, Yin L, Cai J, et al. Activation of BNIP3-mediated mitophagy protects against renal ischemia-reperfusion injury. Cell Death Dis. 2019;10:677 pubmed publisher
  7. Li L, Kang H, Zhang Q, D Agati V, Al Awqati Q, Lin F. FoxO3 activation in hypoxic tubules prevents chronic kidney disease. J Clin Invest. 2019;129:2374-2389 pubmed publisher
  8. Lin X, Cui M, Xu D, Hong D, Xia Y, Xu C, et al. Liver-specific deletion of Eva1a/Tmem166 aggravates acute liver injury by impairing autophagy. Cell Death Dis. 2018;9:768 pubmed publisher
  9. Tsai C, Li C, Cheng Y, Lee C, Liao P, Lin C, et al. The inhibition of lung cancer cell migration by AhR-regulated autophagy. Sci Rep. 2017;7:41927 pubmed publisher
  10. Moulis M, Millet A, Daloyau M, Miquel M, Ronsin B, Wissinger B, et al. OPA1 haploinsufficiency induces a BNIP3-dependent decrease in mitophagy in neurons: relevance to Dominant Optic Atrophy. J Neurochem. 2017;140:485-494 pubmed publisher
  11. Zou P, Liu L, Zheng L, Payne K, Manjili M, Idowu M, et al. Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment. Oxid Med Cell Longev. 2016;2016:4085727 pubmed
  12. Choi H, Merceron C, Mangiavini L, Seifert E, Schipani E, Shapiro I, et al. Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling. Autophagy. 2016;12:1631-46 pubmed publisher
  13. Sun Y, Zheng W, Guo Z, Ju Q, Zhu L, Gao J, et al. A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer. Sci Rep. 2016;6:28083 pubmed publisher
  14. Ono M, Yamada K, Bensaddek D, Afzal V, Biddlestone J, Ortmann B, et al. Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines. PLoS ONE. 2016;11:e0154759 pubmed publisher
  15. Dai X, Zhuang L, Wang D, Zhou T, Chang L, Gai R, et al. Nuclear translocation and activation of YAP by hypoxia contributes to the chemoresistance of SN38 in hepatocellular carcinoma cells. Oncotarget. 2016;7:6933-47 pubmed publisher
  16. Kamino H, Nakamura Y, Tsuneki M, Sano H, Miyamoto Y, Kitamura N, et al. Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer. Oncogenesis. 2016;4:e181 pubmed publisher
  17. Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
  18. Zhang S, Schneider L, Vick B, Grunert M, Jeremias I, Menche D, et al. Anti-leukemic effects of the V-ATPase inhibitor Archazolid A. Oncotarget. 2015;6:43508-28 pubmed publisher
  19. Wu H, Jiang Z, Ding P, Shao L, Liu R. Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells. Sci Rep. 2015;5:12291 pubmed publisher
  20. Moniz S, Bandarra D, Biddlestone J, Campbell K, Komander D, Bremm A, et al. Cezanne regulates E2F1-dependent HIF2α expression. J Cell Sci. 2015;128:3082-93 pubmed publisher
  21. Seillier M, Pouyet L, N Guessan P, Nollet M, Capo F, Guillaumond F, et al. Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med. 2015;7:802-18 pubmed publisher
  22. Polletta L, Vernucci E, Carnevale I, Arcangeli T, Rotili D, Palmerio S, et al. SIRT5 regulation of ammonia-induced autophagy and mitophagy. Autophagy. 2015;11:253-70 pubmed publisher
  23. Ni H, Bhakta A, Wang S, Li Z, Manley S, Huang H, et al. Role of hypoxia inducing factor-1β in alcohol-induced autophagy, steatosis and liver injury in mice. PLoS ONE. 2014;9:e115849 pubmed publisher
  24. Desideri E, Vegliante R, Cardaci S, Nepravishta R, Paci M, Ciriolo M. MAPK14/p38?-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation. Autophagy. 2014;10:1652-65 pubmed publisher
  25. Wang W, Wang Y, Chen H, Xing Y, Li F, Zhang Q, et al. Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat Chem Biol. 2014;10:133-40 pubmed publisher
  26. Ni H, Du K, You M, Ding W. Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity. Am J Pathol. 2013;183:1815-1825 pubmed publisher
  27. Avena P, Anselmo W, Whitaker Menezes D, Wang C, Pestell R, Lamb R, et al. Compartment-specific activation of PPAR? governs breast cancer tumor growth, via metabolic reprogramming and symbiosis. Cell Cycle. 2013;12:1360-70 pubmed publisher
  28. Al Zoubi M, Salem A, Martinez Outschoorn U, Whitaker Menezes D, Lamb R, Hulit J, et al. Creating a tumor-resistant microenvironment: cell-mediated delivery of TNF? completely prevents breast cancer tumor formation in vivo. Cell Cycle. 2013;12:480-90 pubmed publisher
  29. Sánchez Alvarez R, Martinez Outschoorn U, Lin Z, Lamb R, Hulit J, Howell A, et al. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. Cell Cycle. 2013;12:289-301 pubmed publisher
  30. Sánchez Alvarez R, Martinez Outschoorn U, Lamb R, Hulit J, Howell A, Gandara R, et al. Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin. Cell Cycle. 2013;12:172-82 pubmed publisher
  31. Van Beersel G, Tihon E, Demine S, Hamer I, Jadot M, Arnould T. Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts. Biosci Rep. 2013;33:e00023 pubmed publisher
  32. Salem A, Howell A, Sartini M, Sotgia F, Lisanti M. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1?, autophagy and ketone body production. Cell Cycle. 2012;11:4167-73 pubmed publisher