This is a Validated Antibody Database (VAD) review about rat Birc5, based on 34 published articles (read how Labome selects the articles), using Birc5 antibody in all methods. It is aimed to help Labome visitors find the most suited Birc5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Birc5 synonym: AP14; baculoviral IAP repeat-containing protein 5; apoptosis inhibitor survivin

Santa Cruz Biotechnology
mouse monoclonal (D-8)
  • western blot; human; loading ...; fig 5f
Santa Cruz Biotechnology Birc5 antibody (Santa, sc-17779) was used in western blot on human samples (fig 5f). Oncogene (2019) ncbi
mouse monoclonal (D-8)
  • western blot; human; 1:200; loading ...; fig s3
Santa Cruz Biotechnology Birc5 antibody (SantaCruz, SC-17779) was used in western blot on human samples at 1:200 (fig s3). Nat Commun (2017) ncbi
mouse monoclonal (D-8)
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology Birc5 antibody (SantaCruz, sc17779) was used in western blot on human samples (fig 2b). Nucleic Acids Res (2017) ncbi
mouse monoclonal (D-8)
  • western blot; human; fig 2b
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in western blot on human samples (fig 2b). Oncol Lett (2017) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 6b
In order to reveal critical and diverse functions of WD repeat domain 62 in neocortical development, Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in immunohistochemistry on mouse samples at 1:100 (fig 6b). Sci Rep (2017) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry; human; 1:100; loading ...; fig s3
In order to describe a novel role for the neuronal apoptosis inhibitory protein in addition to anti-apoptotic and innate immunology functions, Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in immunohistochemistry on human samples at 1:100 (fig s3). Sci Rep (2017) ncbi
mouse monoclonal (D-8)
  • western blot; human; loading ...; fig 2b
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in western blot on human samples (fig 2b). Int J Biochem Cell Biol (2017) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry; human; 1:50; fig 4
  • western blot; human; 1:200
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, BIRC5 D-8) was used in immunohistochemistry on human samples at 1:50 (fig 4) and in western blot on human samples at 1:200. J Clin Endocrinol Metab (2016) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Mol Clin Oncol (2016) ncbi
mouse monoclonal (D-8)
  • immunocytochemistry; human; 1:300; fig 1
  • western blot; human; fig 2
In order to characterize shared and distinct features compared with aurora-B chromosome passenger protein complex by Aurora-C interactions with INCENP and survivin, Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in immunocytochemistry on human samples at 1:300 (fig 1) and in western blot on human samples (fig 2). PLoS ONE (2016) ncbi
mouse monoclonal (D-8)
  • flow cytometry; human; 1:25; fig 1b
  • immunohistochemistry; human; loading ...; fig 1a
  • western blot; human; 1:50; fig 1d
In order to assess the effect of shepherdin, a peptido-mimetic that inhibits the heat shock protein-Survivin interaction, in retinoblastoma, Santa Cruz Biotechnology Birc5 antibody (Santacruz, sc-17779) was used in flow cytometry on human samples at 1:25 (fig 1b), in immunohistochemistry on human samples (fig 1a) and in western blot on human samples at 1:50 (fig 1d). Chem Biol Interact (2016) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry - paraffin section; human; fig 5
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in immunohistochemistry - paraffin section on human samples (fig 5). Mod Pathol (2016) ncbi
mouse monoclonal (D-8)
  • western blot; human; fig 1
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in western blot on human samples (fig 1). Oncotarget (2016) ncbi
mouse monoclonal (D-8)
  • western blot; human; fig 5
In order to examine the effects of brusatol on the cellular proteome in a mutant non-small cell lung cancer cell line, Santa Cruz Biotechnology Birc5 antibody (Santa Cruz Biotechnology, sc-17779) was used in western blot on human samples (fig 5). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (D-8)
  • western blot; human; fig 1
In order to analyze protection of urothelial cell carcinoma from treatment-induced DNA damage via YAP activation, Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in western blot on human samples (fig 1). Oncogene (2016) ncbi
mouse monoclonal (D-8)
  • western blot; mouse; loading ...; fig 7d
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, 17779) was used in western blot on mouse samples (fig 7d). Oncotarget (2015) ncbi
mouse monoclonal (D-8)
  • western blot; human; 1:75
In order to determine the prognostic role of the Wnt-signaling antagonist SFRP1 in bladder cancer, Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in western blot on human samples at 1:75. J Cancer Res Clin Oncol (2015) ncbi
mouse monoclonal (D-8)
  • western blot; human
In order to evaluate the role of leptin/STAT3 and HER2 receptor in tamoxifen resistance, Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc-17779) was used in western blot on human samples . Cell Oncol (Dordr) (2015) ncbi
mouse monoclonal (D-8)
  • western blot; mouse; fig 6
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz Biotechnology, sc-17779) was used in western blot on mouse samples (fig 6). Free Radic Biol Med (2015) ncbi
mouse monoclonal (D-8)
  • western blot; human
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz Biotechnology, sc-17779) was used in western blot on human samples . Cell Signal (2014) ncbi
mouse monoclonal (D-8)
  • western blot; human
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz Biotechnology, D-8) was used in western blot on human samples . Mol Cancer Ther (2014) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry - paraffin section; human; 1:50
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz Biotechnology, clone D8) was used in immunohistochemistry - paraffin section on human samples at 1:50. Oral Dis (2014) ncbi
mouse monoclonal (D-8)
  • immunohistochemistry - paraffin section; human; 1:50
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz, sc17779) was used in immunohistochemistry - paraffin section on human samples at 1:50. Exp Ther Med (2012) ncbi
mouse monoclonal (D-8)
  • western blot; human; 1:100
Santa Cruz Biotechnology Birc5 antibody (Santa Cruz Biotechnology, sc17779) was used in western blot on human samples at 1:100. Eur J Cancer (2012) ncbi
Novus Biologicals
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 3d
  • western blot; human; loading ...; fig 4b
In order to dose MDAMB231 breast cancer cells with paclitaxel, causing them to generate exosomes highly enriched with Survivin, Novus Biologicals Birc5 antibody (Novus Biologicals, NB500-201) was used in immunocytochemistry on human samples (fig 3d) and in western blot on human samples (fig 4b). Cancers (Basel) (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1c
Novus Biologicals Birc5 antibody (Novus, 500-201L) was used in western blot on human samples (fig 1c). Cell Signal (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:300; loading ...; fig 3
In order to analyze the localization of chromosomal passenger complex (CPC) after treatment with HDACi during cell division., Novus Biologicals Birc5 antibody (Novus Biologicals, NB500-201) was used in immunocytochemistry on human samples at 1:300 (fig 3). Methods Mol Biol (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Novus Biologicals Birc5 antibody (Novus Biologicals, NB500-201) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:500; fig 6c
Novus Biologicals Birc5 antibody (Novusbio, NB500-201) was used in immunohistochemistry on human samples at 1:500 (fig 6c). Oncotarget (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Novus Biologicals Birc5 antibody (Novus, NB500-201) was used in western blot on human samples at 1:1000 (fig 3). EMBO Mol Med (2015) ncbi
Abcam
rabbit polyclonal
  • immunohistochemistry; human; 1:400; fig 4
Abcam Birc5 antibody (Abcam, Ab469) was used in immunohistochemistry on human samples at 1:400 (fig 4). J Clin Endocrinol Metab (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1
Abcam Birc5 antibody (Abcam, ab469) was used in western blot on human samples at 1:1000 (fig 1). Mol Med Rep (2016) ncbi
rabbit monoclonal (EPR2675)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Abcam Birc5 antibody (Abcam, ab134170) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Onco Targets Ther (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 4f
  • immunoprecipitation; human; loading ...; fig 2f
  • western blot; human; loading ...; fig 2a
Abcam Birc5 antibody (Abcam, ab469) was used in immunohistochemistry - paraffin section on human samples (fig 4f), in immunoprecipitation on human samples (fig 2f) and in western blot on human samples (fig 2a). Oncotarget (2015) ncbi
Invitrogen
rabbit polyclonal
  • western blot; mouse
In order to investigate hepatocarcinogenesis mediated by hepatitis B virus X protein, Invitrogen Birc5 antibody (Labvision, PA1-16836) was used in western blot on mouse samples . Mol Cancer (2014) ncbi
Articles Reviewed
  1. Urtishak K, Wang L, Culjkovic Kraljacic B, Davenport J, Porazzi P, Vincent T, et al. Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019;38:2241-2262 pubmed publisher
  2. Oldrini B, Hsieh W, Erdjument Bromage H, Codega P, Carro M, Curiel García A, et al. EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017;8:2035 pubmed publisher
  3. Periyasamy M, Singh A, Gemma C, Kranjec C, Farzan R, Leach D, et al. p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells. Nucleic Acids Res. 2017;45:11056-11069 pubmed publisher
  4. Liu Z, Li H, Liu J, Wu M, Chen X, Liu L, et al. Inactivated Wnt signaling in resveratrol-treated epidermal squamous cancer cells and its biological implication. Oncol Lett. 2017;14:2239-2243 pubmed publisher
  5. Sgourdou P, Mishra Gorur K, Saotome I, Henagariu O, Tuysuz B, Campos C, et al. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Sci Rep. 2017;7:43708 pubmed publisher
  6. Abadía Molina F, Morón Calvente V, Baird S, Shamim F, Martin F, MacKenzie A. Neuronal apoptosis inhibitory protein (NAIP) localizes to the cytokinetic machinery during cell division. Sci Rep. 2017;7:39981 pubmed publisher
  7. Kreger B, Johansen E, Cerione R, Antonyak M. The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance. Cancers (Basel). 2016;8: pubmed
  8. Park S, Jwa E, Shin S, Ju E, Park I, Pak J, et al. Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. Int J Biochem Cell Biol. 2017;83:47-55 pubmed publisher
  9. Schafer C, Göder A, Beyer M, Kiweler N, Mahendrarajah N, Rauch A, et al. Class I histone deacetylases regulate p53/NF-?B crosstalk in cancer cells. Cell Signal. 2017;29:218-225 pubmed publisher
  10. Unruhe Knauf B, Knauer S. Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization. Methods Mol Biol. 2017;1510:47-59 pubmed
  11. Fotouhi O, Kjellin H, Larsson C, Hashemi J, Barriuso J, Juhlin C, et al. Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors. J Clin Endocrinol Metab. 2016;101:3616-3627 pubmed
  12. Takasaki C, Kobayashi M, Ishibashi H, Akashi T, Okubo K. Expression of hypoxia-inducible factor-1? affects tumor proliferation and antiapoptosis in surgically resected lung cancer. Mol Clin Oncol. 2016;5:295-300 pubmed
  13. Sasai K, Katayama H, Hawke D, Sen S. Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS ONE. 2016;11:e0157305 pubmed publisher
  14. Venkatesan N, Kanwar J, Deepa P, Navaneethakrishnan S, Joseph C, Krishnakumar S. Targeting HSP90/Survivin using a cell permeable structure based peptido-mimetic shepherdin in retinoblastoma. Chem Biol Interact. 2016;252:141-9 pubmed publisher
  15. Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed publisher
  16. Andersson E, Arvidsson Y, Swärd C, Hofving T, Wängberg B, Kristiansson E, et al. Expression profiling of small intestinal neuroendocrine tumors identifies subgroups with clinical relevance, prognostic markers and therapeutic targets. Mod Pathol. 2016;29:616-29 pubmed publisher
  17. Zhang S, Liu B, Fan Z, Wang D, Liu Y, Li J, et al. Targeted inhibition of survivin with YM155 promotes apoptosis of hypoxic human pulmonary arterial smooth muscle cells via the upregulation of voltage-dependent K⁺ channels. Mol Med Rep. 2016;13:3415-22 pubmed publisher
  18. Li Y, Lu W, Saini S, Moukha Chafiq O, Pathak V, Ananthan S. Identification of quinazoline compounds as novel potent inhibitors of Wnt/?-catenin signaling in colorectal cancer cells. Oncotarget. 2016;7:11263-70 pubmed publisher
  19. Vartanian S, Ma T, Lee J, Haverty P, Kirkpatrick D, Yu K, et al. Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis. Mol Cell Proteomics. 2016;15:1220-31 pubmed publisher
  20. Ciamporcero E, Shen H, Ramakrishnan S, Yu Ku S, Chintala S, Shen L, et al. YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage. Oncogene. 2016;35:1541-53 pubmed publisher
  21. Li C, Wang L, Zheng L, Zhan X, Xu B, Jiang J, et al. SIRT1 expression is associated with poor prognosis of lung adenocarcinoma. Onco Targets Ther. 2015;8:977-84 pubmed publisher
  22. De Cesare M, Cominetti D, Doldi V, Lopergolo A, Deraco M, Gandellini P, et al. Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin. Oncotarget. 2015;6:13119-32 pubmed
  23. Sadowski S, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, et al. Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis. Oncotarget. 2015;6:18038-49 pubmed
  24. Raimondi L, De Luca A, Amodio N, Manno M, Raccosta S, Taverna S, et al. Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation. Oncotarget. 2015;6:13772-89 pubmed
  25. Meidhof S, Brabletz S, Lehmann W, Preca B, Mock K, Ruh M, et al. ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med. 2015;7:831-47 pubmed publisher
  26. Rogler A, Kendziorra E, Giedl J, Stoehr C, Taubert H, Goebell P, et al. Functional analyses and prognostic significance of SFRP1 expression in bladder cancer. J Cancer Res Clin Oncol. 2015;141:1779-90 pubmed publisher
  27. Papanikolaou V, Stefanou N, Dubos S, Papathanasiou I, Palianopoulou M, Valiakou V, et al. Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes. Cell Oncol (Dordr). 2015;38:155-64 pubmed publisher
  28. Olayanju A, Copple I, Bryan H, Edge G, Sison R, Wong M, et al. Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. Free Radic Biol Med. 2015;78:202-12 pubmed publisher
  29. Zhang W, Lu Z, Kong G, Gao Y, Wang T, Wang Q, et al. Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP. Mol Cancer. 2014;13:128 pubmed publisher
  30. Leiphrakpam P, Rajput A, Mathiesen M, Agarwal E, Lazenby A, Are C, et al. Ezrin expression and cell survival regulation in colorectal cancer. Cell Signal. 2014;26:868-79 pubmed publisher
  31. Cheng Y, Holloway M, Nguyen K, McCauley D, Landesman Y, Kauffman M, et al. XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer. Mol Cancer Ther. 2014;13:675-86 pubmed publisher
  32. Lauxen I, Oliveira M, Rados P, Lingen M, Nor J, Sant Ana Filho M. Immunoprofiling of oral squamous cell carcinomas reveals high p63 and survivin expression. Oral Dis. 2014;20:e76-80 pubmed publisher
  33. Kobayashi M, Huang C, Sonobe M, Kikuchi R, Ishikawa M, Kitamura J, et al. Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients. Exp Ther Med. 2012;3:952-958 pubmed
  34. Liu D, Kadota K, Ueno M, Nakashima N, Yokomise H, Huang C. Adenoviral vector expressing short hairpin RNA targeting Wnt2B has an effective antitumour activity against Wnt2B2-overexpressing tumours. Eur J Cancer. 2012;48:1208-18 pubmed publisher