This is a Validated Antibody Database (VAD) review about rat Atm, based on 108 published articles (read how Labome selects the articles), using Atm antibody in all methods. It is aimed to help Labome visitors find the most suited Atm antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
mouse monoclonal (2C1 (1A1))
  • western blot knockout validation; human; 1:1000; loading ...; fig 6b
Abcam Atm antibody (Abcam, ab78) was used in western blot knockout validation on human samples at 1:1000 (fig 6b). Nat Commun (2016) ncbi
Abcam
mouse monoclonal (2C1 (1A1))
  • western blot knockout validation; mouse; 1:1000; fig s1
In order to characterize a conditional knock out of ataxia telangiectasia-mutated as a mouse model of pancreatic ductal adenocarcinoma, Abcam Atm antibody (Abcam, ab78) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1). Nat Commun (2015) ncbi
Abcam
mouse monoclonal (2C1 (1A1))
  • western blot knockout validation; mouse; fig 2
Abcam Atm antibody (Abcam, AB78) was used in western blot knockout validation on mouse samples (fig 2). Mol Cell Biol (2013) ncbi
Rockland Immunochemicals
mouse monoclonal (10H11.E12)
  • western blot knockout validation; mouse; fig 2
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in western blot knockout validation on mouse samples (fig 2). Mol Cell Biol (2013) ncbi
Abcam
mouse monoclonal (2C1 (1A1))
  • western blot; human; 1:800; fig 3a
Abcam Atm antibody (Abcam, ab78) was used in western blot on human samples at 1:800 (fig 3a). Redox Biol (2021) ncbi
mouse monoclonal (2C1 (1A1))
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s4b
Abcam Atm antibody (Abcam, ab78) was used in immunohistochemistry - paraffin section on mouse samples (fig s4b). Int J Mol Sci (2021) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human; 1:800; loading ...; fig s6a
  • western blot; mouse; 1:800; loading ...; fig 6d
Abcam Atm antibody (Abcam, ab78) was used in western blot on human samples at 1:800 (fig s6a) and in western blot on mouse samples at 1:800 (fig 6d). Redox Biol (2021) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; loading ...; fig 5l
Abcam Atm antibody (Abcam, ab36810) was used in immunocytochemistry on human samples (fig 5l). elife (2020) ncbi
mouse monoclonal (10H11.E12)
  • immunohistochemistry; human; 1:250; loading ...; fig 3c
Abcam Atm antibody (abcam, ab36810) was used in immunohistochemistry on human samples at 1:250 (fig 3c). Acta Neuropathol (2020) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human; 1:1000; loading ...; fig 5h
Abcam Atm antibody (abcam, ab78) was used in western blot on human samples at 1:1000 (fig 5h). Cell Death Dis (2018) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; loading ...; fig 4b
Abcam Atm antibody (Abcam, ab36810) was used in immunocytochemistry on human samples (fig 4b). Cancer Discov (2017) ncbi
mouse monoclonal (2C1 (1A1))
  • immunocytochemistry; human; 1:100; fig s6a
In order to identify the protein ATM as a target for senescence alleviation through chemical screen, Abcam Atm antibody (Abcam, ab78) was used in immunocytochemistry on human samples at 1:100 (fig s6a). Nat Chem Biol (2017) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; loading ...; fig 6a
Abcam Atm antibody (Abcam, ab36810) was used in immunocytochemistry on human samples (fig 6a). J Cell Physiol (2017) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; mouse; loading ...; fig 5b
In order to engineer and characterize a second-generation, high-affinity AXL decoy receptor, Abcam Atm antibody (Abcam, ab78) was used in western blot on mouse samples (fig 5b). J Clin Invest (2017) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; loading ...; fig 6c
In order to use knockout mice to determine if GRK6 contributes to hematopoiesis, Abcam Atm antibody (Abcam, ab36810) was used in western blot on human samples (fig 6c). Cell Death Dis (2016) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; rat; 1:500; loading ...; fig 4c
Abcam Atm antibody (Abcam, ab36810) was used in immunocytochemistry on rat samples at 1:500 (fig 4c). Oncotarget (2016) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot knockout validation; human; 1:1000; loading ...; fig 6b
Abcam Atm antibody (Abcam, ab78) was used in western blot knockout validation on human samples at 1:1000 (fig 6b). Nat Commun (2016) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; loading ...; fig 7e
Abcam Atm antibody (abcam, ab36810) was used in western blot on human samples (fig 7e). PLoS ONE (2016) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; loading ...; fig 3c
Abcam Atm antibody (Abcam, ab36810) was used in immunocytochemistry on human samples (fig 3c). Stem Cell Reports (2015) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human; loading ...; fig 1d
Abcam Atm antibody (Abcam, 2C1A1) was used in western blot on human samples (fig 1d). Stem Cell Reports (2015) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot knockout validation; mouse; 1:1000; fig s1
In order to characterize a conditional knock out of ataxia telangiectasia-mutated as a mouse model of pancreatic ductal adenocarcinoma, Abcam Atm antibody (Abcam, ab78) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1). Nat Commun (2015) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human; 1:1000; fig 5
Abcam Atm antibody (Abcam, ab78) was used in western blot on human samples at 1:1000 (fig 5). Sci Rep (2015) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human; fig s11
Abcam Atm antibody (abcam, ab78) was used in western blot on human samples (fig s11). Cell Death Differ (2015) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; fig 4
Abcam Atm antibody (ABCAM, ab36810) was used in immunocytochemistry on human samples (fig 4). Oncotarget (2015) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human
Abcam Atm antibody (Abcam, ab78) was used in western blot on human samples . Cancer Res (2014) ncbi
mouse monoclonal (10H11.E12)
  • western blot; mouse; 1:1000; fig 3c
Abcam Atm antibody (Abcam, ab36810) was used in western blot on mouse samples at 1:1000 (fig 3c). Nat Neurosci (2014) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human
Abcam Atm antibody (Abcam, ab36810) was used in immunocytochemistry on human samples . Cell Res (2014) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; fig 4
Abcam Atm antibody (Abcam, ab36810) was used in western blot on human samples (fig 4). J Pharmacol Sci (2014) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human
Abcam Atm antibody (Abcam, Ab-78) was used in western blot on human samples . Mol Neurobiol (2014) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human
Abcam Atm antibody (Abcam, 2C1) was used in western blot on human samples . Cell Cycle (2013) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot knockout validation; mouse; fig 2
Abcam Atm antibody (Abcam, AB78) was used in western blot knockout validation on mouse samples (fig 2). Mol Cell Biol (2013) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; human
Abcam Atm antibody (Abcam, ab78) was used in western blot on human samples . Oncogenesis (2012) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; mouse; 1:2000
Abcam Atm antibody (Abcam, ab78) was used in western blot on mouse samples at 1:2000. J Biol Chem (2013) ncbi
mouse monoclonal (10H11.E12)
  • western blot; mouse
Abcam Atm antibody (Abcam, 6810) was used in western blot on mouse samples . J Biol Chem (2012) ncbi
mouse monoclonal (2C1 (1A1))
  • western blot; mouse
Abcam Atm antibody (Abcam, ab78) was used in western blot on mouse samples . J Biol Chem (2012) ncbi
Santa Cruz Biotechnology
mouse monoclonal (1B10)
  • western blot; human; loading ...; fig 4a
Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc135663) was used in western blot on human samples (fig 4a). Sci Rep (2021) ncbi
mouse monoclonal (2C1)
  • western blot; mouse; 1:1000; loading ...; fig 1e
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-23921) was used in western blot on mouse samples at 1:1000 (fig 1e). Cancer Discov (2019) ncbi
mouse monoclonal (1B10)
  • western blot; human; loading ...; fig 2d
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-135663) was used in western blot on human samples (fig 2d). Sci Signal (2018) ncbi
mouse monoclonal (1B10)
  • western blot; E. coli; fig 6a
Santa Cruz Biotechnology Atm antibody (Santa Cruz, 1B10) was used in western blot on E. coli samples (fig 6a). Nucleic Acids Res (2017) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; fig 2a
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-47739) was used in western blot on human samples (fig 2a). PLoS ONE (2017) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 2a
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-23921) was used in western blot on human samples (fig 2a). PLoS ONE (2017) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; fig 4
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-47739) was used in western blot on human samples (fig 4). Mol Med Rep (2016) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 2a
In order to examine ultraviolet radiation-induced ATR and ATM recruitment during G1 and S phases, Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-23921) was used in western blot on human samples (fig 2a). PLoS ONE (2016) ncbi
mouse monoclonal
  • flow cytometry; human; 1:50; loading ...; fig 7d
  • western blot; human; 1:500; loading ...; fig 2b
Santa Cruz Biotechnology Atm antibody (Santa Cruz, 10H11.E12) was used in flow cytometry on human samples at 1:50 (fig 7d) and in western blot on human samples at 1:500 (fig 2b). Mol Cancer Res (2016) ncbi
mouse monoclonal (10H11.E12)
  • flow cytometry; human; 1:50; loading ...; fig 7d
  • western blot; human; 1:500; loading ...; fig 2b
Santa Cruz Biotechnology Atm antibody (Santa Cruz, 10H11.E12) was used in flow cytometry on human samples at 1:50 (fig 7d) and in western blot on human samples at 1:500 (fig 2b). Mol Cancer Res (2016) ncbi
mouse monoclonal (10H11.E12)
  • western blot; mouse; fig 4a
Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc-47739) was used in western blot on mouse samples (fig 4a). Nucleic Acids Res (2016) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; 1:100; loading ...; fig st3
  • western blot; human; 1:500; loading ...; fig st3
In order to study the DNA damage response in senescent epithelial cells, Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-47739) was used in immunocytochemistry on human samples at 1:100 (fig st3) and in western blot on human samples at 1:500 (fig st3). Nat Commun (2016) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-47739) was used in western blot on human samples . Nucleus (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 3
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-23921) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 4
Santa Cruz Biotechnology Atm antibody (Santa-Cruz, sc-23921) was used in western blot on human samples (fig 4). Nucleic Acids Res (2016) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 2
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-23921) was used in western blot on human samples (fig 2). Mol Cell Biol (2016) ncbi
mouse monoclonal (2C1)
  • western blot; human; 1:1000; loading ...; fig 4e
Santa Cruz Biotechnology Atm antibody (Santa Cruz, 2C1) was used in western blot on human samples at 1:1000 (fig 4e). Oncogene (2016) ncbi
mouse monoclonal (5C2)
  • western blot; human; 1:1000; fig 5
In order to characterize inhibition of gamma-irradiation-induced apoptosis of prostate cancer cells by elevated expression of hepatoma up-regulated protein, Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc-23922) was used in western blot on human samples at 1:1000 (fig 5). J Cell Biochem (2016) ncbi
mouse monoclonal (2C1)
  • immunoprecipitation; human; fig 5
  • western blot; human; 1:1000; fig 3
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-23921) was used in immunoprecipitation on human samples (fig 5) and in western blot on human samples at 1:1000 (fig 3). Nucleic Acids Res (2016) ncbi
mouse monoclonal (2C1)
  • western blot; rat; 1:1000; fig 3d
  • western blot; human; 1:1000; fig 3f
In order to investigate how ataxia-telangiectasia mutated signaling regulates pexophagy, Santa Cruz Biotechnology Atm antibody (santa cruz, SC-23921) was used in western blot on rat samples at 1:1000 (fig 3d) and in western blot on human samples at 1:1000 (fig 3f). Nat Cell Biol (2015) ncbi
mouse monoclonal (1B10)
  • western blot; human; 1:200
In order to study kinases involved in H2AX phosphorylation in irradiated human keratinocytes, Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc-135663) was used in western blot on human samples at 1:200. Cell Mol Life Sci (2015) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-47739) was used in immunocytochemistry on human samples . Mutat Res (2014) ncbi
mouse monoclonal (2C1)
  • western blot; mouse
Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc-23921) was used in western blot on mouse samples . J Cell Biol (2015) ncbi
mouse monoclonal (10H11.E12)
  • western blot; mouse
Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc-47739) was used in western blot on mouse samples . J Cell Biol (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human
In order to examine the role of NF-kappaB during the human papillomavirus life cycle, Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, 2C1) was used in western blot on human samples . J Virol (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig s7
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-23921) was used in western blot on human samples (fig s7). Nucleic Acids Res (2015) ncbi
mouse monoclonal (10H11.E12)
  • immunohistochemistry - paraffin section; human; 1:100; fig 2
  • western blot; human; fig s1
In order to characterize how peripheral metabolic deregulation is induced by Alzheimer-associated A-beta oligomers that impact the central nervous system, Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc-47739) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2) and in western blot on human samples (fig s1). EMBO Mol Med (2015) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; fig 4b
Santa Cruz Biotechnology Atm antibody (Santa, sc-47739) was used in western blot on human samples (fig 4b). Genes Dev (2014) ncbi
mouse monoclonal (2C1)
  • western blot; human
Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc-23921) was used in western blot on human samples . Mol Cell Biol (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human; 1:1000; fig 7d
In order to show that the zinc finger E-box binding homeobox 1 regulates radiosensitivity and the DNA damage response in breast cancer cells, Santa Cruz Biotechnology Atm antibody (Santa, sc-23921) was used in western blot on human samples at 1:1000 (fig 7d). Nat Cell Biol (2014) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; fig 2
Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotech, sc47739) was used in immunocytochemistry on human samples (fig 2). Nature (2014) ncbi
mouse monoclonal (2C1)
  • western blot; human
Santa Cruz Biotechnology Atm antibody (Santa Cruz, sc-23921) was used in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (2C1)
  • western blot; human; 1:1000
Santa Cruz Biotechnology Atm antibody (Santa Cruz, 2C1) was used in western blot on human samples at 1:1000. Oncogene (2014) ncbi
mouse monoclonal (10H11.E12)
  • western blot; mouse
Santa Cruz Biotechnology Atm antibody (Santa Cruz Biotechnology, sc-47739) was used in western blot on mouse samples . Int J Cancer (2013) ncbi
GeneTex
mouse monoclonal (2C1)
  • western blot; human; loading ...
GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples . Autophagy (2020) ncbi
mouse monoclonal (2C1)
  • western blot; human; 1:1000; loading ...; fig 5b
GeneTex Atm antibody (Genetex, GTX70103) was used in western blot on human samples at 1:1000 (fig 5b). Genes Cancer (2019) ncbi
mouse monoclonal (2C1)
  • western blot; human; 1:500; loading ...; fig 1f
GeneTex Atm antibody (GeneTex, 70103) was used in western blot on human samples at 1:500 (fig 1f). Nat Commun (2018) ncbi
mouse monoclonal (2C1)
  • western blot; human; loading ...; fig s2e
In order to examine the effects of the arginine methyltransferase PRMT5 on homologous recombination-mediated double-strand break repair, GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples (fig s2e). Mol Cell (2017) ncbi
mouse monoclonal (2C1)
  • western blot; mouse; fig 3
GeneTex Atm antibody (Genetex, GTX70103) was used in western blot on mouse samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (2C1)
  • immunoprecipitation; human; fig 4
GeneTex Atm antibody (GeneTex, GTX70103) was used in immunoprecipitation on human samples (fig 4). Nat Commun (2016) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 5
GeneTex Atm antibody (Genetex, GTX70103) was used in western blot on human samples (fig 5). Genes Dev (2016) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 1
GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples (fig 1). Cell Cycle (2016) ncbi
mouse monoclonal (2C1)
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 4
GeneTex Atm antibody (GeneTex, GTX70103) was used in immunocytochemistry on human samples (fig 2) and in western blot on human samples (fig 4). Carcinogenesis (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 5
GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples (fig 5). PLoS ONE (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human; 1:1000; loading ...; fig 5b
GeneTex Atm antibody (GeneTex, 2C1) was used in western blot on human samples at 1:1000 (fig 5b). DNA Repair (Amst) (2015) ncbi
mouse monoclonal (2C1)
  • western blot; mouse; loading ...; fig 7a
GeneTex Atm antibody (Genetex, GTX70103) was used in western blot on mouse samples (fig 7a). J Mol Cell Biol (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig s5
GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples (fig s5). J Cell Biol (2015) ncbi
mouse monoclonal (2C1)
  • immunohistochemistry; human; fig 1
GeneTex Atm antibody (Genetex, 2C1) was used in immunohistochemistry on human samples (fig 1). Aging Cell (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 6
GeneTex Atm antibody (Gene Tex, GTX70103) was used in western blot on human samples (fig 6). Mol Cell Biol (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 3
GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples (fig 3). Oncogene (2015) ncbi
mouse monoclonal (2C1)
  • western blot; human
In order to study the effect of Hinokitiol on DNA damage and autophagy in gefitinib-resistant lung adenocarcinoma cells, GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig s2
GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples (fig s2). Mol Cell (2014) ncbi
mouse monoclonal (2C1)
  • western blot; mouse; 1:500
In order to study the role of TGF-beta inhibitors in abolishing the resistance of glioblastoma to ionozing radiation therapy, GeneTex Atm antibody (GeneTex, 2C1) was used in western blot on mouse samples at 1:500. Cancer Res (2012) ncbi
mouse monoclonal (5C2)
  • western blot; mouse; 1:500
In order to evaluate the role of Atm and DNA-PKcs kinases during chromosomal signal joint formation, GeneTex Atm antibody (Genetex, GTX70107) was used in western blot on mouse samples at 1:500. Proc Natl Acad Sci U S A (2011) ncbi
mouse monoclonal (2C1)
  • western blot; human
GeneTex Atm antibody (Genetex, GTX70103) was used in western blot on human samples . Cell Cycle (2010) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 5
In order to show that camptothecin-induced activation of ATM requires transcription, GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples (fig 5). J Biol Chem (2010) ncbi
mouse monoclonal (2C1)
  • western blot; human; fig 2
In order to investigate the mechanism of proteasome-dependent RPA2 phosphorylation, GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples (fig 2). DNA Repair (Amst) (2010) ncbi
mouse monoclonal (5C2)
  • immunocytochemistry; human
GeneTex Atm antibody (GeneTex, GTX70107) was used in immunocytochemistry on human samples . J Virol (2008) ncbi
mouse monoclonal (2C1)
  • immunoprecipitation; human
  • western blot; human
GeneTex Atm antibody (GeneTex, GTX70103) was used in immunoprecipitation on human samples and in western blot on human samples . J Virol (2008) ncbi
mouse monoclonal (2C1)
  • western blot; mouse; 1:500
GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on mouse samples at 1:500. J Biol Chem (2008) ncbi
mouse monoclonal (2C1)
  • western blot; human
In order to investigate the potential role of the proteasome in checkpoint activation and ATM/ATR signaling in response to UV light-induced DNA damage, GeneTex Atm antibody (GeneTex, GTX70103) was used in western blot on human samples . J Biol Chem (2008) ncbi
mouse monoclonal (5C2)
  • western blot; human
GeneTex Atm antibody (GeneTex, GTX70107) was used in western blot on human samples . FEBS Lett (2006) ncbi
mouse monoclonal (2C1)
  • western blot; mouse; 1:1000
GeneTex Atm antibody (Genetex, GTX70103) was used in western blot on mouse samples at 1:1000. Proc Natl Acad Sci U S A (2006) ncbi
Rockland Immunochemicals
mouse monoclonal (10H11.E12)
  • western blot; human; 1:500; loading ...; fig s5d
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in western blot on human samples at 1:500 (fig s5d). Cancer Res (2021) ncbi
mouse monoclonal (10H11.E12)
  • western blot; mouse; 1:1000; fig s5m
Rockland Immunochemicals Atm antibody (Rockland, 200- 301-400) was used in western blot on mouse samples at 1:1000 (fig s5m). Nat Cell Biol (2016) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; loading ...; fig 2c
Rockland Immunochemicals Atm antibody (Rockland, 200301400) was used in immunocytochemistry on human samples (fig 2c). Oncotarget (2016) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; 1:500; fig 5
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in immunocytochemistry on human samples at 1:500 (fig 5). Sci Rep (2016) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; fig 3h
Rockland Immunochemicals Atm antibody (Rockland, 200-301- 400) was used in western blot on human samples (fig 3h). Mol Cell Biol (2015) ncbi
mouse monoclonal (10H11.E12)
  • western blot; mouse; fig s5
Rockland Immunochemicals Atm antibody (Rockland Immunochemicals, 200-301-400) was used in western blot on mouse samples (fig s5). Nat Struct Mol Biol (2015) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; mouse
Rockland Immunochemicals Atm antibody (ROCKLAND, 200-301-400) was used in immunocytochemistry on mouse samples . J Cell Biol (2015) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human
Rockland Immunochemicals Atm antibody (Rockland Immunochemicals, 200-301-400) was used in western blot on human samples . DNA Repair (Amst) (2015) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; 1:500; loading ...; fig 3a
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in western blot on human samples at 1:500 (fig 3a). Oncogene (2015) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; fig s1
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in western blot on human samples (fig s1). Mol Biol Cell (2014) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in immunocytochemistry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (10H11.E12)
  • western blot knockout validation; mouse; fig 2
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in western blot knockout validation on mouse samples (fig 2). Mol Cell Biol (2013) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in immunocytochemistry on human samples . J Thorac Oncol (2013) ncbi
mouse monoclonal (10H11.E12)
  • immunocytochemistry; human; 1:50
Rockland Immunochemicals Atm antibody (Rockland Biochemicals, 200-301-400) was used in immunocytochemistry on human samples at 1:50. Radiat Res (2013) ncbi
mouse monoclonal (10H11.E12)
  • western blot; mouse; 1:1000
Rockland Immunochemicals Atm antibody (Rockland, 200-301-400) was used in western blot on mouse samples at 1:1000. Proc Natl Acad Sci U S A (2006) ncbi
Novus Biologicals
mouse monoclonal (2C1)
  • western blot; mouse; 1:1000; loading ...; fig 5a
Novus Biologicals Atm antibody (Novus Biologicals, NB100-309) was used in western blot on mouse samples at 1:1000 (fig 5a). Cell Death Differ (2018) ncbi
mouse monoclonal (5C2)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2c
In order to determine the effects of modulating autophagy in a mouse model of metastatic cancer, Novus Biologicals Atm antibody (Novus Biologicals, NB100-220) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 2c). J Pharmacol Exp Ther (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig s3
  • immunocytochemistry; human; 1:500; fig 5
  • western blot; human; fig s3
Novus Biologicals Atm antibody (Novus biological, NB100-104) was used in immunoprecipitation on human samples (fig s3), in immunocytochemistry on human samples at 1:500 (fig 5) and in western blot on human samples (fig s3). Sci Rep (2016) ncbi
domestic rabbit polyclonal
Novus Biologicals Atm antibody (Novus Biologicals, NB100-104) was used . Biochem Biophys Res Commun (2015) ncbi
domestic rabbit polyclonal
Novus Biologicals Atm antibody (Novus Biological, NB100-104) was used . Nucleic Acids Res (2015) ncbi
mouse monoclonal (2C1)
  • western blot; rhesus macaque; fig 2
In order to study nuclear African swine fever virus replication, Novus Biologicals Atm antibody (Novus, NB100-309) was used in western blot on rhesus macaque samples (fig 2). Virus Res (2015) ncbi
mouse monoclonal (2C1)
  • immunohistochemistry; human; 1:100
  • immunohistochemistry; rat; 1:100
Novus Biologicals Atm antibody (Novus Biologicals, 2C1) was used in immunohistochemistry on human samples at 1:100 and in immunohistochemistry on rat samples at 1:100. EMBO J (2015) ncbi
Invitrogen
mouse monoclonal (2C1)
  • western blot; human; 1:1000; loading ...; fig s6a
  • western blot; mouse; 1:1000; loading ...; fig 6d
Invitrogen Atm antibody (Thermo, MA123152) was used in western blot on human samples at 1:1000 (fig s6a) and in western blot on mouse samples at 1:1000 (fig 6d). Redox Biol (2021) ncbi
mouse monoclonal (10H11.E12)
  • western blot; human; fig 4a
In order to determine the effect of the hepatitis C viral load on host DNA damage, Invitrogen Atm antibody (Thermo Fisher, MA1-46069) was used in western blot on human samples (fig 4a). PLoS ONE (2017) ncbi
mouse monoclonal (2C1)
  • immunocytochemistry; human; 1:100; loading ...; fig 2e
In order to determine the effect of chronic smoking on repair gene expression in the normal oral mucosa of chronic smokers and never smokers, Invitrogen Atm antibody (Pierce, 2C1) was used in immunocytochemistry on human samples at 1:100 (fig 2e). Arch Oral Biol (2017) ncbi
Articles Reviewed
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  2. Waseem S, Kumar S, Lee K, Yoon B, Kim M, Kim H, et al. Protein Arginine Methyltransferase 1 Is Essential for the Meiosis of Male Germ Cells. Int J Mol Sci. 2021;22: pubmed publisher
  3. Laine A, Nagelli S, Farrington C, Butt U, Cvrljevic A, Vainonen J, et al. CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis. Cancer Res. 2021;81:4319-4331 pubmed publisher
  4. Pramanick A, Chakraborti S, Mahata T, Basak M, Das K, Verma S, et al. G protein β5-ATM complexes drive acetaminophen-induced hepatotoxicity. Redox Biol. 2021;43:101965 pubmed publisher
  5. Ditano J, Donahue K, Tafe L, McCleery C, Eastman A. Sensitivity of cells to ATR and CHK1 inhibitors requires hyperactivation of CDK2 rather than endogenous replication stress or ATM dysfunction. Sci Rep. 2021;11:7077 pubmed publisher
  6. Alessio N, Squillaro T, Di Bernardo G, Galano G, De Rosa R, Melone M, et al. Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence. elife. 2020;9: pubmed publisher
  7. Jo D, Park S, Kim A, Park N, Kim J, Bae J, et al. Loss of HSPA9 induces peroxisomal degradation by increasing pexophagy. Autophagy. 2020;:1-15 pubmed publisher
  8. Santos Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1. Genes Cancer. 2019;10:119-133 pubmed publisher
  9. Nihei Y, Mori K, Werner G, Arzberger T, Zhou Q, Khosravi B, et al. Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. Acta Neuropathol. 2020;139:99-118 pubmed publisher
  10. Zhang J, Lee Y, Dang F, Gan W, Menon A, Katon J, et al. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019;: pubmed publisher
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  14. Lee J, Mand M, Kao C, Zhou Y, Ryu S, Richards A, et al. ATM directs DNA damage responses and proteostasis via genetically separable pathways. Sci Signal. 2018;11: pubmed publisher
  15. Haricharan S, Punturi N, Singh P, Holloway K, Anurag M, Schmelz J, et al. Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer. Cancer Discov. 2017;7:1168-1183 pubmed publisher
  16. Deshpande R, Lee J, Paull T. Rad50 ATPase activity is regulated by DNA ends and requires coordination of both active sites. Nucleic Acids Res. 2017;45:5255-5268 pubmed publisher
  17. Kang H, Park J, Choi K, Kim Y, Choi H, Jung C, et al. Chemical screening identifies ATM as a target for alleviating senescence. Nat Chem Biol. 2017;13:616-623 pubmed publisher
  18. Clarke T, Sanchez Bailon M, Chiang K, Reynolds J, Herrero Ruiz J, Bandeiras T, et al. PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination. Mol Cell. 2017;65:900-916.e7 pubmed publisher
  19. Shin S, Song J, Hwang B, Noh D, Park S, Kim W, et al. HSPA6 augments garlic extract-induced inhibition of proliferation, migration, and invasion of bladder cancer EJ cells; Implication for cell cycle dysregulation, signaling pathway alteration, and transcription factor-associated MMP-9 regulation. PLoS ONE. 2017;12:e0171860 pubmed publisher
  20. Squillaro T, Antonucci I, Alessio N, Esposito A, Cipollaro M, Melone M, et al. Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. J Cell Physiol. 2017;232:3454-3467 pubmed publisher
  21. Wang S, Lai K, Li C, Chiang C, Yu G, Sakamoto N, et al. The Paradoxical Effects of Different Hepatitis C Viral Loads on Host DNA Damage and Repair Abilities. PLoS ONE. 2017;12:e0164281 pubmed publisher
  22. Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed publisher
  23. Le Q, Yao W, Chen Y, Yan B, Liu C, Yuan M, et al. GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal. Cell Death Dis. 2016;7:e2478 pubmed publisher
  24. Hansen R, Mund A, Poulsen S, Sandoval M, Klement K, Tsouroula K, et al. SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. Nat Cell Biol. 2016;18:1357-1366 pubmed publisher
  25. Piechota M, Sunderland P, Wysocka A, Nalberczak M, Sliwinska M, Radwanska K, et al. Is senescence-associated β-galactosidase a marker of neuronal senescence?. Oncotarget. 2016;7:81099-81109 pubmed publisher
  26. Alves M, Carta C, de Barros P, Issa J, Nunes F, Almeida J. Repair genes expression profile of MLH1, MSH2 and ATM in the normal oral mucosa of chronic smokers. Arch Oral Biol. 2017;73:60-65 pubmed publisher
  27. Lee J, Jung H, Han Y, Yoon Y, Yun C, Sun H, et al. Antioxidant effects of Cirsium setidens extract on oxidative stress in human mesenchymal stem cells. Mol Med Rep. 2016;14:3777-84 pubmed publisher
  28. Bakr A, Köcher S, Volquardsen J, Petersen C, Borgmann K, Dikomey E, et al. Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1. Oncotarget. 2016;7:57679-57693 pubmed publisher
  29. Schmid Burgk J, Höning K, Ebert T, Hornung V. CRISPaint allows modular base-specific gene tagging using a ligase-4-dependent mechanism. Nat Commun. 2016;7:12338 pubmed publisher
  30. Ray A, Blevins C, Wani G, Wani A. ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle. PLoS ONE. 2016;11:e0159344 pubmed publisher
  31. Barnard R, Regan D, Hansen R, Maycotte P, Thorburn A, Gustafson D. Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease. J Pharmacol Exp Ther. 2016;358:282-93 pubmed publisher
  32. Su C, Cheng C, Tzeng T, Lin I, Hsu M. An H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity. PLoS ONE. 2016;11:e0156378 pubmed publisher
  33. Qi Y, Qiu Q, Gu X, Tian Y, Zhang Y. ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts. Sci Rep. 2016;6:24700 pubmed publisher
  34. He D, Xiang J, Li B, Liu H. The dynamic behavior of Ect2 in response to DNA damage. Sci Rep. 2016;6:24504 pubmed publisher
  35. Salzman D, Nakamura K, Nallur S, Dookwah M, Metheetrairut C, Slack F, et al. miR-34 activity is modulated through 5'-end phosphorylation in response to DNA damage. Nat Commun. 2016;7:10954 pubmed publisher
  36. Frum R, Love I, Damle P, Mukhopadhyay N, Palit Deb S, Deb S, et al. Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination. Mol Cancer Res. 2016;14:423-36 pubmed publisher
  37. Yang Y, Poe J, Yang L, Fedoriw A, Desai S, Magnuson T, et al. Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo. Nucleic Acids Res. 2016;44:4174-88 pubmed publisher
  38. Wang Y, Xu Q, Sack L, Kang C, Elledge S. A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling. Genes Dev. 2016;30:293-306 pubmed publisher
  39. Nassour J, Martien S, Martin N, Deruy E, Tomellini E, Malaquin N, et al. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells. Nat Commun. 2016;7:10399 pubmed publisher
  40. Kuo C, Li X, Stark J, Shih H, Ann D. RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner. Cell Cycle. 2016;15:787-98 pubmed publisher
  41. Rassoolzadeh H, Coucoravas C, Farnebo M. The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1. Nucleus. 2015;6:417-24 pubmed publisher
  42. Lin L, Swerdel M, Lazaropoulos M, Hoffman G, Toro Ramos A, Wright J, et al. Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. Stem Cell Reports. 2015;5:1097-1108 pubmed publisher
  43. Cataldo A, Cheung D, Balsari A, Tagliabue E, Coppola V, Iorio M, et al. miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response. Oncotarget. 2016;7:786-97 pubmed publisher
  44. Murata Y, Uehara Y, Hosoi Y. Activation of mTORC1 under nutrient starvation conditions increases cellular radiosensitivity in human liver cancer cell lines, HepG2 and HuH6. Biochem Biophys Res Commun. 2015;468:684-90 pubmed publisher
  45. Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed publisher
  46. Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, et al. UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation. Mol Cell Biol. 2016;36:394-406 pubmed publisher
  47. Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed publisher
  48. Hassan M, El Khattouti A, Ejaeidi A, Ma T, Day W, Espinoza I, et al. Elevated Expression of Hepatoma Up-Regulated Protein Inhibits γ-Irradiation-Induced Apoptosis of Prostate Cancer Cells. J Cell Biochem. 2016;117:1308-18 pubmed publisher
  49. Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
  50. Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269 pubmed publisher
  51. Parplys A, Zhao W, Sharma N, Groesser T, Liang F, Maranon D, et al. NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability. Nucleic Acids Res. 2015;43:9817-34 pubmed publisher
  52. Torres M, Pandita R, Kulak O, Kumar R, Formstecher E, Horikoshi N, et al. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability. Mol Cell Biol. 2015;35:3633-45 pubmed publisher
  53. Hartlerode A, Morgan M, Wu Y, Buis J, Ferguson D. Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors. Nat Struct Mol Biol. 2015;22:736-43 pubmed publisher
  54. Russell R, Perkhofer L, Liebau S, Lin Q, Lechel A, Feld F, et al. Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition. Nat Commun. 2015;6:7677 pubmed publisher
  55. Simões M, Martins C, Ferreira F. Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus. Virus Res. 2015;210:1-7 pubmed publisher
  56. Chou W, Hu L, Hsiung C, Shen C. Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway. Carcinogenesis. 2015;36:832-40 pubmed publisher
  57. Yu H, Xie J, Li B, Sun Y, Gao Q, Ding Z, et al. TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway. Sci Rep. 2015;5:9853 pubmed publisher
  58. Benzina S, Pitaval A, Lemercier C, Lustremant C, Frouin V, Wu N, et al. A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation. Cell Mol Life Sci. 2015;72:3559-73 pubmed publisher
  59. Nakajima N, Hagiwara Y, Oike T, Okayasu R, Murakami T, Nakano T, et al. Pre-exposure to ionizing radiation stimulates DNA double strand break end resection, promoting the use of homologous recombination repair. PLoS ONE. 2015;10:e0122582 pubmed publisher
  60. Batenburg N, Thompson E, Hendrickson E, Zhu X. Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation. EMBO J. 2015;34:1399-416 pubmed publisher
  61. Stellas D, Souliotis V, Bekyrou M, Smirlis D, Kirsch Volders M, Degrassi F, et al. Benzo[a]pyrene-induced cell cycle arrest in HepG2 cells is associated with delayed induction of mitotic instability. Mutat Res. 2014;769:59-68 pubmed publisher
  62. Kumari A, Owen N, Juarez E, McCullough A. BLM protein mitigates formaldehyde-induced genomic instability. DNA Repair (Amst). 2015;28:73-82 pubmed publisher
  63. Ruan X, Zuo Q, Jia H, Chau J, Lin J, Ao J, et al. P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers. J Mol Cell Biol. 2015;7:105-18 pubmed publisher
  64. Warren D, Tajsic T, Porter L, Minaisah R, Cobb A, Jacob A, et al. Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death Differ. 2015;22:1540-50 pubmed publisher
  65. Zellweger R, Dalcher D, Mutreja K, Berti M, Schmid J, Herrador R, et al. Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells. J Cell Biol. 2015;208:563-79 pubmed publisher
  66. Xiong J, Todorova D, Su N, Kim J, Lee P, Shen Z, et al. Stemness factor Sall4 is required for DNA damage response in embryonic stem cells. J Cell Biol. 2015;208:513-20 pubmed publisher
  67. Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed publisher
  68. Ekumi K, Paculova H, Lenasi T, Pospichalova V, Bösken C, Rybarikova J, et al. Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex. Nucleic Acids Res. 2015;43:2575-89 pubmed publisher
  69. Gibbs Seymour I, Markiewicz E, Bekker Jensen S, Mailand N, Hutchison C. Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage. Aging Cell. 2015;14:162-9 pubmed publisher
  70. Clarke J, Lyra e Silva N, Figueiredo C, Frozza R, Ledo J, Beckman D, et al. Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. EMBO Mol Med. 2015;7:190-210 pubmed publisher
  71. Alessio N, Del Gaudio S, Capasso S, Di Bernardo G, Cappabianca S, Cipollaro M, et al. Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process. Oncotarget. 2015;6:8155-66 pubmed
  72. Ray Chaudhuri A, Ahuja A, Herrador R, Lopes M. Poly(ADP-ribosyl) glycohydrolase prevents the accumulation of unusual replication structures during unperturbed S phase. Mol Cell Biol. 2015;35:856-65 pubmed publisher
  73. Henriksson S, Rassoolzadeh H, Hedström E, Coucoravas C, Julner A, Goldstein M, et al. The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair. Genes Dev. 2014;28:2726-38 pubmed publisher
  74. Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
  75. Sekimoto T, Oda T, Kurashima K, Hanaoka F, Yamashita T. Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication. Mol Cell Biol. 2015;35:699-715 pubmed publisher
  76. Kawasumi M, Bradner J, Tolliday N, Thibodeau R, Sloan H, Brummond K, et al. Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity. Cancer Res. 2014;74:7534-45 pubmed publisher
  77. Hühn D, Kousholt A, Sørensen C, Sartori A. miR-19, a component of the oncogenic miR-17∼92 cluster, targets the DNA-end resection factor CtIP. Oncogene. 2015;34:3977-84 pubmed publisher
  78. Li L, Wu P, Lee J, Li P, Hsieh W, Ho C, et al. Hinokitiol induces DNA damage and autophagy followed by cell cycle arrest and senescence in gefitinib-resistant lung adenocarcinoma cells. PLoS ONE. 2014;9:e104203 pubmed publisher
  79. Wei F, Ojo D, Lin X, Wong N, He L, Yan J, et al. BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation. Oncogene. 2015;34:3063-75 pubmed publisher
  80. Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
  81. Smith C, Matheson T, Trombly D, Sun X, Campeau E, Han X, et al. A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli. Mol Biol Cell. 2014;25:2866-81 pubmed publisher
  82. Manguan García C, Pintado Berninches L, Carrillo J, Machado Pinilla R, Sastre L, Perez Quilis C, et al. Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells. PLoS ONE. 2014;9:e101424 pubmed publisher
  83. Katyal S, Lee Y, Nitiss K, Downing S, Li Y, Shimada M, et al. Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes. Nat Neurosci. 2014;17:813-21 pubmed publisher
  84. Gad H, Koolmeister T, Jemth A, Eshtad S, Jacques S, Ström C, et al. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature. 2014;508:215-21 pubmed publisher
  85. Gao M, Wei W, Li M, Wu Y, Ba Z, Jin K, et al. Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination. Cell Res. 2014;24:532-41 pubmed publisher
  86. Chung Y, Pan C, Liou W, Sheu M, Lin W, Chen T, et al. NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway. J Pharmacol Sci. 2014;124:7-17 pubmed
  87. Belanger F, Rajotte V, Drobetsky E. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts. PLoS ONE. 2014;9:e85294 pubmed publisher
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  89. Ferlazzo M, Sonzogni L, Granzotto A, Bodgi L, Lartin O, Devic C, et al. Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates. Mol Neurobiol. 2014;49:1200-11 pubmed publisher
  90. Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T. SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways. Cell Cycle. 2013;12:3770-80 pubmed publisher
  91. Shamma A, Suzuki M, Hayashi N, Kobayashi M, Sasaki N, Nishiuchi T, et al. ATM mediates pRB function to control DNMT1 protein stability and DNA methylation. Mol Cell Biol. 2013;33:3113-24 pubmed publisher
  92. Sappino A, Buser R, Seguin Q, Fernet M, Lesne L, Gumy Pause F, et al. The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage. Oncogenesis. 2012;1:e7 pubmed publisher
  93. Birkelbach M, Ferraiolo N, Gheorghiu L, Pfäffle H, Daly B, Ebright M, et al. Detection of impaired homologous recombination repair in NSCLC cells and tissues. J Thorac Oncol. 2013;8:279-86 pubmed publisher
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  104. Ariumi Y, Kuroki M, Dansako H, Abe K, Ikeda M, Wakita T, et al. The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication. J Virol. 2008;82:9639-46 pubmed publisher
  105. Yalcin S, Zhang X, Luciano J, Mungamuri S, Marinkovic D, Vercherat C, et al. Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. J Biol Chem. 2008;283:25692-705 pubmed publisher
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  108. Pusapati R, Rounbehler R, Hong S, Powers J, Yan M, Kiguchi K, et al. ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. Proc Natl Acad Sci U S A. 2006;103:1446-51 pubmed