This is a Validated Antibody Database (VAD) review about rat Arrb1, based on 18 published articles (read how Labome selects the articles), using Arrb1 antibody in all methods. It is aimed to help Labome visitors find the most suited Arrb1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Arrb1 synonym: BARRES

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (25-G10)
  • western blot knockout validation; mouse; 1:500; loading ...; fig s2a
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 1d
Santa Cruz Biotechnology Arrb1 antibody (Santa Cruz, 53780) was used in western blot knockout validation on mouse samples at 1:500 (fig s2a) and in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 1d). Cell Death Differ (2021) ncbi
Abcam
domestic rabbit monoclonal (E274)
  • immunocytochemistry; mouse; 1:200; loading ...; fig 6a
Abcam Arrb1 antibody (Abcam, Ab32099) was used in immunocytochemistry on mouse samples at 1:200 (fig 6a). Stem Cell Res Ther (2020) ncbi
domestic rabbit monoclonal (E274)
  • western blot; human; loading ...; fig 4a
Abcam Arrb1 antibody (Abcam, ab32099) was used in western blot on human samples (fig 4a). Cell Rep (2019) ncbi
domestic rabbit monoclonal (E274)
  • immunohistochemistry - paraffin section; human; 1:200
In order to correlate beta-arrestin1 and NF-kappaB expression and the clinicopathological characteristics in lung adenocarcinoma, Abcam Arrb1 antibody (Abcam, Ab-32099) was used in immunohistochemistry - paraffin section on human samples at 1:200. Tumour Biol (2015) ncbi
domestic rabbit monoclonal (E274)
  • western blot; human; 1:1000
Abcam Arrb1 antibody (Abcam, Ab32099) was used in western blot on human samples at 1:1000. Braz J Med Biol Res (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (25-G10)
  • western blot knockout validation; mouse; 1:500; loading ...; fig s2a
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 1d
Santa Cruz Biotechnology Arrb1 antibody (Santa Cruz, 53780) was used in western blot knockout validation on mouse samples at 1:500 (fig s2a) and in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 1d). Cell Death Differ (2021) ncbi
mouse monoclonal (A-1)
  • immunoprecipitation; mouse; loading ...; fig 1a
  • immunocytochemistry; mouse; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 1a
Santa Cruz Biotechnology Arrb1 antibody (Santa Cruz, A-1) was used in immunoprecipitation on mouse samples (fig 1a), in immunocytochemistry on mouse samples (fig 3a) and in western blot on mouse samples (fig 1a). Mol Pharmacol (2017) ncbi
mouse monoclonal
  • immunoprecipitation; mouse; loading ...; fig 1a
  • immunocytochemistry; mouse; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 1a
Santa Cruz Biotechnology Arrb1 antibody (Santa Cruz, A-1) was used in immunoprecipitation on mouse samples (fig 1a), in immunocytochemistry on mouse samples (fig 3a) and in western blot on mouse samples (fig 1a). Mol Pharmacol (2017) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1f
In order to propose that mu opioid receptor sequences are important determinants of functional selectivity in the opioid system, Invitrogen Arrb1 antibody (Pierce, PA1-730) was used in western blot on human samples at 1:1000 (fig 1f). Mol Pharmacol (2017) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; fig s1f
In order to analyze beta-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium determined by Smoothened, Invitrogen Arrb1 antibody (Thermo Fisher Scientific, PA1-730) was used in immunocytochemistry on mouse samples (fig s1f). J Cell Biol (2016) ncbi
mouse monoclonal (ZA005)
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig s2
In order to investigate the role of Mn superoxide dismutase in tissue regeneration using transgenic mice, Invitrogen Arrb1 antibody (Invitrogen, 39-5000) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig s2). Free Radic Biol Med (2010) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D24H9)
  • western blot; human; 1:1000; loading ...; fig 3g
Cell Signaling Technology Arrb1 antibody (Cell Signaling, 4674) was used in western blot on human samples at 1:1000 (fig 3g). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D24H9)
  • western blot; mouse; 1:1000; loading ...; fig 3f
Cell Signaling Technology Arrb1 antibody (CST, CST#4674S) was used in western blot on mouse samples at 1:1000 (fig 3f). elife (2020) ncbi
mouse monoclonal (6-24)
  • western blot; human; loading ...; fig s5b
Cell Signaling Technology Arrb1 antibody (Cell Signaling, 2416) was used in western blot on human samples (fig s5b). Cell (2019) ncbi
domestic rabbit monoclonal (D24H9)
  • western blot; rat; 1:1000; fig s9
Cell Signaling Technology Arrb1 antibody (Cell Signaling, 4674) was used in western blot on rat samples at 1:1000 (fig s9). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D24H9)
  • immunoprecipitation; human; 1:1000; fig 2
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Arrb1 antibody (Cell Signaling, 4674) was used in immunoprecipitation on human samples at 1:1000 (fig 2) and in western blot on human samples at 1:1000 (fig 2). Front Pharmacol (2016) ncbi
domestic rabbit monoclonal (D24H9)
  • western blot; human; 1:1000; fig 5
Cell Signaling Technology Arrb1 antibody (Cell Signaling, 4674) was used in western blot on human samples at 1:1000 (fig 5). Nature (2015) ncbi
domestic rabbit monoclonal (D24H9)
  • immunoprecipitation; human
  • western blot; human
Cell Signaling Technology Arrb1 antibody (Cell Signaling, D24H9) was used in immunoprecipitation on human samples and in western blot on human samples . Arch Biochem Biophys (2015) ncbi
domestic rabbit monoclonal (D24H9)
  • western blot; mouse; 1:5000
Cell Signaling Technology Arrb1 antibody (Cell Signaling Technology, 4674) was used in western blot on mouse samples at 1:5000. PLoS ONE (2014) ncbi
Bioworld
  • western blot; rat; 1:500; loading ...; fig 6a
In order to propose that claudin-4 is required for mAChR-modulated paracellular permeability of epithelial cells and investigate the mechanism, Bioworld Arrb1 antibody (Bioworld Technology, BS2213) was used in western blot on rat samples at 1:500 (fig 6a). J Cell Sci (2015) ncbi
Articles Reviewed
  1. De Groof T, Bergkamp N, Heukers R, Giap T, Bebelman M, Goeij de Haas R, et al. Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies. Nat Commun. 2021;12:4357 pubmed publisher
  2. Fang Y, Jiang Q, Li S, Zhu H, Xu R, Song N, et al. Opposing functions of β-arrestin 1 and 2 in Parkinson's disease via microglia inflammation and Nprl3. Cell Death Differ. 2021;28:1822-1836 pubmed publisher
  3. Bele S, Girada S, Ray A, Gupta A, Oruganti S, Prakash Babu P, et al. MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-induced obese mice. elife. 2020;9: pubmed publisher
  4. Hou M, Han J, Li G, Kwon M, Jiang J, Emani S, et al. Multipotency of mouse trophoblast stem cells. Stem Cell Res Ther. 2020;11:55 pubmed publisher
  5. Coulombe P, Paliouras G, Clayton A, Hussainkhel A, Fuller M, Jovanovic V, et al. Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling. Cell Rep. 2019;27:1769-1780.e4 pubmed publisher
  6. Quitterer U, Fu X, Pohl A, Bayoumy K, Langer A, AbdAlla S. Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers. Cell. 2019;176:318-333.e19 pubmed publisher
  7. Weinberg Z, Zajac A, Phan T, Shiwarski D, Puthenveedu M. Sequence-Specific Regulation of Endocytic Lifetimes Modulates Arrestin-Mediated Signaling at the µ Opioid Receptor. Mol Pharmacol. 2017;91:416-427 pubmed publisher
  8. Blume L, Patten T, Eldeeb K, Leone Kabler S, Ilyasov A, Keegan B, et al. Cannabinoid Receptor Interacting Protein 1a Competition with ?-Arrestin for CB1 Receptor Binding Sites. Mol Pharmacol. 2017;91:75-86 pubmed publisher
  9. Pal K, Hwang S, Somatilaka B, Badgandi H, Jackson P, DeFea K, et al. Smoothened determines ?-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. J Cell Biol. 2016;212:861-75 pubmed publisher
  10. Cannavo A, Liccardo D, Eguchi A, Elliott K, Traynham C, Ibetti J, et al. Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun. 2016;7:10877 pubmed publisher
  11. Vukićević T, Schulz M, Faust D, Klussmann E. The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells-a Potential Target for Pharmacological Intervention in Cardiovascular Diseases. Front Pharmacol. 2016;7:23 pubmed publisher
  12. Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  13. Cong X, Zhang Y, Li J, Mei M, Ding C, Xiang R, et al. Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells. J Cell Sci. 2015;128:2271-86 pubmed publisher
  14. Yu J, Wang L, Zhang T, Shen H, Dong W, Ni Y, et al. Co-expression of β-arrestin1 and NF-кB is associated with cancer progression and poor prognosis in lung adenocarcinoma. Tumour Biol. 2015;36:6551-8 pubmed publisher
  15. Ghorbani A, Jeddi Tehrani M, Saidpour A, Safa M, Bayat A, Zand H. PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells. Arch Biochem Biophys. 2015;566:58-66 pubmed publisher
  16. Fraisier C, Koraka P, Belghazi M, Bakli M, Granjeaud S, Pophillat M, et al. Kinetic analysis of mouse brain proteome alterations following Chikungunya virus infection before and after appearance of clinical symptoms. PLoS ONE. 2014;9:e91397 pubmed publisher
  17. Zhan J, Xiao F, Zhang Z, Wang Y, Chen K, Wang Y. Effect of penehyclidine hydrochloride on β-arrestin-1 expression in lipopolysaccharide-induced human pulmonary microvascular endothelial cells. Braz J Med Biol Res. 2013;46:1040-1046 pubmed
  18. Kim A, Joseph S, Khan A, Epstein C, Sobel R, Huang T. Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radic Biol Med. 2010;48:1501-12 pubmed publisher