This is a Validated Antibody Database (VAD) review about rat Ap2m1, based on 16 published articles (read how Labome selects the articles), using Ap2m1 antibody in all methods. It is aimed to help Labome visitors find the most suited Ap2m1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ap2m1 synonym: Ap50; Clapm1; mu2

Knockout validation
Abcam
domestic rabbit monoclonal (EP2695Y)
  • western blot knockout validation; human; loading ...; fig 5e
Abcam Ap2m1 antibody (Abcam, ab75995) was used in western blot knockout validation on human samples (fig 5e). Sci Adv (2020) ncbi
Abcam
domestic rabbit monoclonal (EP2695Y)
  • western blot knockout validation; human; loading ...; fig 5e
Abcam Ap2m1 antibody (Abcam, ab75995) was used in western blot knockout validation on human samples (fig 5e). Sci Adv (2020) ncbi
domestic rabbit monoclonal (EP2695Y)
  • western blot; human; loading ...; fig 2l
Abcam Ap2m1 antibody (Abcam, ab75995) was used in western blot on human samples (fig 2l). Cell Rep (2019) ncbi
domestic rabbit monoclonal (EPR4700)
  • western blot; roundworm ; 1:1000; fig 7a
Abcam Ap2m1 antibody (Abcam, 109397) was used in western blot on roundworm samples at 1:1000 (fig 7a). elife (2019) ncbi
domestic rabbit monoclonal (EPR4700)
  • western blot; human; 1:1000; loading ...; fig 2i, 3a
Abcam Ap2m1 antibody (Abcam, ab109397) was used in western blot on human samples at 1:1000 (fig 2i, 3a). Cell Rep (2019) ncbi
domestic rabbit monoclonal (EP2695Y)
  • western blot; human; 1:1000; loading ...; fig 2i, 3a
Abcam Ap2m1 antibody (Abcam, ab75995) was used in western blot on human samples at 1:1000 (fig 2i, 3a). Cell Rep (2019) ncbi
domestic rabbit monoclonal (EP2695Y)
  • western blot; human; 1:1000; fig 2c
In order to elucidate the role of endocytic pathways in Andes virus infection, Abcam Ap2m1 antibody (Abcam, ab75995) was used in western blot on human samples at 1:1000 (fig 2c). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (EPR4700)
  • western blot; rat; 1:4000
Abcam Ap2m1 antibody (Epitomics, 3312-1) was used in western blot on rat samples at 1:4000. Mol Neurobiol (2014) ncbi
Invitrogen
chicken polyclonal
In order to study how cellular localization affects DHHC5 activity, Invitrogen Ap2m1 antibody (Thermo Scientific, PA5-20745) was used . Nat Commun (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D4F3)
  • western blot; human; 1:1000; loading ...; fig 1e
Cell Signaling Technology Ap2m1 antibody (Cell Signaling Technology, 7399) was used in western blot on human samples at 1:1000 (fig 1e). elife (2020) ncbi
BD Biosciences
mouse monoclonal (31/AP50)
  • western blot; mouse; loading ...; fig 1b
BD Biosciences Ap2m1 antibody (BD Biosciences, 611351) was used in western blot on mouse samples (fig 1b). Sci Adv (2022) ncbi
mouse monoclonal (31/AP50)
  • western blot; human; 1:1000; loading ...; fig 1e
BD Biosciences Ap2m1 antibody (BD Biosciences, 611350) was used in western blot on human samples at 1:1000 (fig 1e). elife (2020) ncbi
mouse monoclonal (31/AP50)
  • western blot; mouse; 1:1000; loading ...; fig ev1a
BD Biosciences Ap2m1 antibody (BD Transduction, 611350) was used in western blot on mouse samples at 1:1000 (fig ev1a). EMBO Rep (2020) ncbi
mouse monoclonal (31/AP50)
  • western blot; human; loading ...; fig 3e
BD Biosciences Ap2m1 antibody (BD Biosciences, 611350) was used in western blot on human samples (fig 3e). Dev Cell (2019) ncbi
mouse monoclonal (31/AP50)
  • western blot; mouse; loading ...; fig 1c
BD Biosciences Ap2m1 antibody (BD Biosciences, 611351) was used in western blot on mouse samples (fig 1c). J Neurosci (2018) ncbi
mouse monoclonal (31/AP50)
  • western blot; human; fig s5
BD Biosciences Ap2m1 antibody (BD Bioscience, 611351) was used in western blot on human samples (fig s5). Mol Ther (2015) ncbi
mouse monoclonal (31/AP50)
  • immunohistochemistry - paraffin section; mouse; fig 4,5
In order to study the role of excitotoxicity in neuronal death, BD Biosciences Ap2m1 antibody (BD Biosciences, 611351) was used in immunohistochemistry - paraffin section on mouse samples (fig 4,5). J Neurosci (2015) ncbi
mouse monoclonal (31/AP50)
  • western blot; human; 1:500; loading ...; fig 5a
BD Biosciences Ap2m1 antibody (BD Transduction Laboratories, 611350) was used in western blot on human samples at 1:500 (fig 5a). elife (2014) ncbi
mouse monoclonal (31/AP50)
  • immunocytochemistry; mouse; 1:500
BD Biosciences Ap2m1 antibody (BD Biosciences, 611350) was used in immunocytochemistry on mouse samples at 1:500. J Comp Neurol (2014) ncbi
Articles Reviewed
  1. Azarnia Tehran D, Kochlamazashvili G, Pampaloni N, Sposini S, Shergill J, Lehmann M, et al. Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity. Sci Adv. 2022;8:eabl5032 pubmed publisher
  2. Yuan S, Chu H, Huang J, Zhao X, Ye Z, Lai P, et al. Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target. Sci Adv. 2020;6:eaba7910 pubmed publisher
  3. Cendrowski J, Kaczmarek M, Mazur M, Kuzmicz Kowalska K, Jastrzębski K, Brewińska Olchowik M, et al. Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells. elife. 2020;9: pubmed publisher
  4. Bera S, Camblor Perujo S, Calleja Barca E, Negrete Hurtado A, Racho J, de Bruyckere E, et al. AP-2 reduces amyloidogenesis by promoting BACE1 trafficking and degradation in neurons. EMBO Rep. 2020;21:e47954 pubmed publisher
  5. Laufer J, Hauser M, Kindinger I, Purvanov V, Pauli A, Legler D. Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation. Cell Rep. 2019;29:995-1009.e6 pubmed publisher
  6. Partlow E, Baker R, Beacham G, Chappie J, Leschziner A, Hollopeter G. A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. elife. 2019;8: pubmed publisher
  7. Gulbranson D, Crisman L, Lee M, Ouyang Y, Menasche B, Demmitt B, et al. AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated Endocytosis. Dev Cell. 2019;50:436-446.e5 pubmed publisher
  8. Agajanian M, Walker M, Axtman A, Ruela de Sousa R, Serafin D, Rabinowitz A, et al. WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop. Cell Rep. 2019;26:79-93.e8 pubmed publisher
  9. Kuliyev E, Gingras S, Guy C, Howell S, Vogel P, Pelletier S. Overlapping Role of SCYL1 and SCYL3 in Maintaining Motor Neuron Viability. J Neurosci. 2018;38:2615-2630 pubmed publisher
  10. Chiang C, Flint M, Lin J, Spiropoulou C. Endocytic Pathways Used by Andes Virus to Enter Primary Human Lung Endothelial Cells. PLoS ONE. 2016;11:e0164768 pubmed publisher
  11. Moody P, Sayers E, Magnusson J, Alexander C, Borri P, Watson P, et al. Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes. Mol Ther. 2015;23:1888-98 pubmed publisher
  12. Brigidi G, Santyr B, Shimell J, Jovellar B, Bamji S. Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5. Nat Commun. 2015;6:8200 pubmed publisher
  13. Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed publisher
  14. Umasankar P, Ma L, Thieman J, Jha A, Doray B, Watkins S, et al. A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing. elife. 2014;3: pubmed publisher
  15. Li C, Lu Y, Zhou M, Zong X, Li C, Xu X, et al. Activation of GABAB receptors ameliorates cognitive impairment via restoring the balance of HCN1/HCN2 surface expression in the hippocampal CA1 area in rats with chronic cerebral hypoperfusion. Mol Neurobiol. 2014;50:704-20 pubmed publisher
  16. Oetjen S, Mahlke C, Hermans Borgmeyer I, Hermey G. Spatiotemporal expression analysis of the growth factor receptor SorCS3. J Comp Neurol. 2014;522:3386-402 pubmed publisher