This is a Validated Antibody Database (VAD) review about rat Anxa2, based on 27 published articles (read how Labome selects the articles), using Anxa2 antibody in all methods. It is aimed to help Labome visitors find the most suited Anxa2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Anxa2 synonym: ANX2

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (3D5)
  • western blot knockout validation; human; fig 3c
Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, sc47696) was used in western blot knockout validation on human samples (fig 3c). Nat Commun (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D11G2)
  • western blot knockout validation; human; fig 3c
Cell Signaling Technology Anxa2 antibody (Cell Signaling, 8235) was used in western blot knockout validation on human samples (fig 3c). Nat Commun (2020) ncbi
BD Biosciences
mouse monoclonal (5/Annexin II)
  • western blot knockout validation; human; loading ...; fig 1a
BD Biosciences Anxa2 antibody (BD Biosciences, 610069) was used in western blot knockout validation on human samples (fig 1a). Sci Rep (2018) ncbi
BD Biosciences
mouse monoclonal (5/Annexin II)
  • immunocytochemistry knockout validation; mouse; fig 1
  • immunohistochemistry knockout validation; mouse; fig 1
BD Biosciences Anxa2 antibody (BD Pharmingen), 610069) was used in immunocytochemistry knockout validation on mouse samples (fig 1) and in immunohistochemistry knockout validation on mouse samples (fig 1). Mol Cancer Res (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-10)
  • western blot; mouse; 1:500; loading ...; fig 2a
Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, SC-28,385) was used in western blot on mouse samples at 1:500 (fig 2a). Virulence (2021) ncbi
mouse monoclonal (3D5)
  • western blot knockout validation; human; fig 3c
Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, sc47696) was used in western blot knockout validation on human samples (fig 3c). Nat Commun (2020) ncbi
mouse monoclonal (C-10)
  • western blot; mouse; loading ...; fig 2i
Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz Biotechnology Inc, sc-28385) was used in western blot on mouse samples (fig 2i). Cancer Res (2018) ncbi
mouse monoclonal (85.Tyr 24)
  • immunocytochemistry; rat; 1:20; loading ...; fig 3
In order to investigate the role of Ser25 phosphorylation in subcellular localization of Annexin A2 and its interaction with mRNP complexes, Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, sc-135753) was used in immunocytochemistry on rat samples at 1:20 (fig 3). FEBS Open Bio (2017) ncbi
mouse monoclonal (85.Tyr 24)
  • western blot; human; loading ...; fig 2a
In order to present the role of CD147 in cancer migration through annexin A2 and DOCK3-catenin-WAVE2 signaling, Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, sc-135753) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
mouse monoclonal (H-5)
  • immunocytochemistry; human; fig 1a
  • western blot; human; loading ...; fig 3c
In order to present the role of CD147 in cancer migration through annexin A2 and DOCK3-catenin-WAVE2 signaling, Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, sc-48397) was used in immunocytochemistry on human samples (fig 1a) and in western blot on human samples (fig 3c). Oncotarget (2016) ncbi
mouse monoclonal (85.Tyr 24)
  • immunocytochemistry; rat; 1:20; fig 4
  • western blot; rat; 1:200; fig 5
In order to study how Tyr23 phosphorylation regulates AnxA2 function, Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz Biotechnologies, sc-135753) was used in immunocytochemistry on rat samples at 1:20 (fig 4) and in western blot on rat samples at 1:200 (fig 5). J Cell Sci (2016) ncbi
mouse monoclonal (C-10)
  • western blot; human; 1:1000; fig 1
Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, sc-28385) was used in western blot on human samples at 1:1000 (fig 1). Mol Psychiatry (2015) ncbi
mouse monoclonal (3D5)
  • chromatin immunoprecipitation; human; 1:100; fig 2
In order to determine how starvation-induced autophagy is promoted by transcriptional regulation of Annexin A2, Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, 3D5) was used in chromatin immunoprecipitation on human samples at 1:100 (fig 2). Nat Commun (2015) ncbi
mouse monoclonal (11.Tyr 24)
  • western blot; human
Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz Biotechnology, sc-135752) was used in western blot on human samples . Transl Res (2015) ncbi
mouse monoclonal (C-10)
  • western blot; human; loading ...; fig 3d
In order to perform a proteomic analysis of HBV-infected HepG2 cells to identify changes in proteins involved in cell migration, Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, sc-28385) was used in western blot on human samples (fig 3d). PLoS ONE (2014) ncbi
mouse monoclonal (3D5)
Santa Cruz Biotechnology Anxa2 antibody (Santa Cruz, sc-47696) was used . Obesity (Silver Spring) (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR13052(B))
  • western blot; human; loading ...; fig 5b, 5k
Abcam Anxa2 antibody (Abcam, ab178677) was used in western blot on human samples (fig 5b, 5k). Cell (2019) ncbi
domestic rabbit monoclonal (EPR13052(B))
  • western blot; human; fig 4
Abcam Anxa2 antibody (Abcam, ab178677) was used in western blot on human samples (fig 4). Arthritis Rheumatol (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D11G2)
  • immunocytochemistry; human; fig 4d
Cell Signaling Technology Anxa2 antibody (CST, 8235) was used in immunocytochemistry on human samples (fig 4d). Molecules (2021) ncbi
domestic rabbit monoclonal (D11G2)
  • western blot knockout validation; human; fig 3c
Cell Signaling Technology Anxa2 antibody (Cell Signaling, 8235) was used in western blot knockout validation on human samples (fig 3c). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D11G2)
  • immunocytochemistry; mouse; fig 2a
  • western blot; mouse; loading ...; fig 1g
Cell Signaling Technology Anxa2 antibody (Cell Signaling, 8235) was used in immunocytochemistry on mouse samples (fig 2a) and in western blot on mouse samples (fig 1g). Biomolecules (2020) ncbi
domestic rabbit monoclonal (D11G2)
  • immunoprecipitation; mouse; loading ...; fig s5a
  • western blot; mouse; loading ...; fig s5a
Cell Signaling Technology Anxa2 antibody (Cell Signaling, 8235) was used in immunoprecipitation on mouse samples (fig s5a) and in western blot on mouse samples (fig s5a). Sci Rep (2018) ncbi
domestic rabbit monoclonal (D11G2)
  • immunocytochemistry; human
In order to study retinal degeneration caused by disruption of the microtubule-binding and membrane-binding domains of CEP290, Cell Signaling Technology Anxa2 antibody (Cell Signaling, 8235) was used in immunocytochemistry on human samples . J Clin Invest (2013) ncbi
BD Biosciences
mouse monoclonal (5/Annexin II)
  • western blot; human; loading ...; fig 3a
BD Biosciences Anxa2 antibody (BD Transduction, 610,068) was used in western blot on human samples (fig 3a). BMC Cardiovasc Disord (2019) ncbi
mouse monoclonal (5/Annexin II)
  • western blot knockout validation; human; loading ...; fig 1a
BD Biosciences Anxa2 antibody (BD Biosciences, 610069) was used in western blot knockout validation on human samples (fig 1a). Sci Rep (2018) ncbi
mouse monoclonal (5/Annexin II)
  • western blot; mouse; fig 4a
In order to describe extracellular vesicle subpopulations secreted by fat cells, BD Biosciences Anxa2 antibody (BD Biosciences, 610068) was used in western blot on mouse samples (fig 4a). J Extracell Vesicles (2017) ncbi
mouse monoclonal (5/Annexin II)
  • western blot; rat; 1:1000; loading ...; fig 4b
In order to investigate the role of Ser25 phosphorylation in subcellular localization of Annexin A2 and its interaction with mRNP complexes, BD Biosciences Anxa2 antibody (BD Biosciences, 610069) was used in western blot on rat samples at 1:1000 (fig 4b). FEBS Open Bio (2017) ncbi
mouse monoclonal (5/Annexin II)
  • western blot; human; loading ...; fig 1a
BD Biosciences Anxa2 antibody (BD Transduction Laboratories, 610068) was used in western blot on human samples (fig 1a). PLoS ONE (2016) ncbi
mouse monoclonal (5/Annexin II)
  • western blot; human; loading ...; fig 4
BD Biosciences Anxa2 antibody (BD Transduction lab, 610069) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
mouse monoclonal (5/Annexin II)
  • western blot; rat; 1:1000; fig 6
In order to study how Tyr23 phosphorylation regulates AnxA2 function, BD Biosciences Anxa2 antibody (BD Biosciences, 610069) was used in western blot on rat samples at 1:1000 (fig 6). J Cell Sci (2016) ncbi
mouse monoclonal (5/Annexin II)
  • immunocytochemistry; human; fig 3
  • immunohistochemistry; human; fig 5
  • western blot; human; fig 4
In order to demonstrate the transcriptional repression of ANXA2 by ERG in prostate epithelial cells and discuss how this interaction relates to prostate cancer, BD Biosciences Anxa2 antibody (BD Biosciences, 610068) was used in immunocytochemistry on human samples (fig 3), in immunohistochemistry on human samples (fig 5) and in western blot on human samples (fig 4). Mol Cancer Res (2015) ncbi
mouse monoclonal (5/Annexin II)
  • immunocytochemistry knockout validation; mouse; fig 1
  • immunohistochemistry knockout validation; mouse; fig 1
BD Biosciences Anxa2 antibody (BD Pharmingen), 610069) was used in immunocytochemistry knockout validation on mouse samples (fig 1) and in immunohistochemistry knockout validation on mouse samples (fig 1). Mol Cancer Res (2015) ncbi
mouse monoclonal (5/Annexin II)
  • immunohistochemistry - paraffin section; human; 1:1,000
  • western blot; human; 1:5,000
BD Biosciences Anxa2 antibody (BD Biosciences, 610069) was used in immunohistochemistry - paraffin section on human samples at 1:1,000 and in western blot on human samples at 1:5,000. Biomed Res (2014) ncbi
mouse monoclonal (5/Annexin II)
  • immunocytochemistry; human
In order to demonstrate that Listeria monocytogenes uses efferocytosis to promote cell-to-cell spread during infection, BD Biosciences Anxa2 antibody (BD Biosciences, 610068) was used in immunocytochemistry on human samples . Nature (2014) ncbi
mouse monoclonal (6/p36/MAT1)
  • western blot; human; 1:4000
BD Biosciences Anxa2 antibody (BD Biosciences, 610532) was used in western blot on human samples at 1:4000. Clin Exp Immunol (2014) ncbi
Articles Reviewed
  1. Hu Y, Park N, Seo K, Park J, Somarathne R, Olivier A, et al. Pneumococcal surface adhesion A protein (PsaA) interacts with human Annexin A2 on airway epithelial cells. Virulence. 2021;12:1841-1854 pubmed publisher
  2. Nii T, Konno K, Matsumoto M, Bhukhai K, Borwornpinyo S, Sakai K, et al. The Bioactive Peptide SL-13R Expands Human Umbilical Cord Blood Hematopoietic Stem and Progenitor Cells In Vitro. Molecules. 2021;26: pubmed publisher
  3. Talwar D, Messens J, Dick T. A role for annexin A2 in scaffolding the peroxiredoxin 2-STAT3 redox relay complex. Nat Commun. 2020;11:4512 pubmed publisher
  4. Anselmino N, Bizzotto J, Sanchis P, Lage Vickers S, Ortiz E, Valacco P, et al. HO-1 Interactors Involved in the Colonization of the Bone Niche: Role of ANXA2 in Prostate Cancer Progression. Biomolecules. 2020;10: pubmed publisher
  5. Weisell J, Ohukainen P, Näpänkangas J, Ohlmeier S, Bergmann U, Peltonen T, et al. Heat shock protein 90 is downregulated in calcific aortic valve disease. BMC Cardiovasc Disord. 2019;19:306 pubmed publisher
  6. Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed publisher
  7. Hakuno D, Kimura M, Ito S, Satoh J, Nakashima Y, Horie T, et al. Hepatokine α1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction. Sci Rep. 2018;8:16749 pubmed publisher
  8. Taylor J, Fernandez D, Thornton S, Skeate J, Lühen K, Da Silva D, et al. Heterotetrameric annexin A2/S100A10 (A2t) is essential for oncogenic human papillomavirus trafficking and capsid disassembly, and protects virions from lysosomal degradation. Sci Rep. 2018;8:11642 pubmed publisher
  9. Wan Y, Wang L, Zhu C, Zheng Q, Wang G, Tong J, et al. Aptamer-Conjugated Extracellular Nanovesicles for Targeted Drug Delivery. Cancer Res. 2018;78:798-808 pubmed publisher
  10. Durcin M, Fleury A, Taillebois E, Hilairet G, Krupova Z, Henry C, et al. Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles. J Extracell Vesicles. 2017;6:1305677 pubmed publisher
  11. Aukrust I, Rosenberg L, Ankerud M, Bertelsen V, Hollås H, Saraste J, et al. Post-translational modifications of Annexin A2 are linked to its association with perinuclear nonpolysomal mRNP complexes. FEBS Open Bio. 2017;7:160-173 pubmed publisher
  12. Dismuke W, Klingeborn M, Stamer W. Mechanism of Fibronectin Binding to Human Trabecular Meshwork Exosomes and Its Modulation by Dexamethasone. PLoS ONE. 2016;11:e0165326 pubmed publisher
  13. Madureira P, Bharadwaj A, Bydoun M, Garant K, O Connell P, Lee P, et al. Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10. Oncotarget. 2016;7:47720-47737 pubmed publisher
  14. Cui H, Wang S, Miao J, Fu Z, Feng F, Wu J, et al. CD147 regulates cancer migration via direct interaction with Annexin A2 and DOCK3-β-catenin-WAVE2 signaling. Oncotarget. 2016;7:5613-29 pubmed publisher
  15. Grindheim A, Hollås H, Raddum A, Saraste J, Vedeler A. Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2. J Cell Sci. 2016;129:314-28 pubmed publisher
  16. Lee K, Westin L, Kim J, Chang J, Oh Y, Amreen B, et al. Alteration by p11 of mGluR5 localization regulates depression-like behaviors. Mol Psychiatry. 2015;20:1546-56 pubmed publisher
  17. Moreau K, Ghislat G, Hochfeld W, Renna M, Zavodszky E, Runwal G, et al. Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy. Nat Commun. 2015;6:8045 pubmed publisher
  18. Yalavarthi S, Gould T, Rao A, Mazza L, Morris A, Nuñez Alvarez C, et al. Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the antiphospholipid syndrome. Arthritis Rheumatol. 2015;67:2990-3003 pubmed publisher
  19. Tristante E, Martínez C, Jiménez S, Mora L, Carballo F, Martínez Lacaci I, et al. Association of a characteristic membrane pattern of annexin A2 with high invasiveness and nodal status in colon adenocarcinoma. Transl Res. 2015;166:196-206 pubmed publisher
  20. Griner N, Young D, Chaudhary P, Mohamed A, Huang W, Chen Y, et al. ERG oncoprotein inhibits ANXA2 expression and function in prostate cancer. Mol Cancer Res. 2015;13:368-79 pubmed publisher
  21. Jung Y, Wang J, Lee E, McGee S, Berry J, Yumoto K, et al. Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow. Mol Cancer Res. 2015;13:197-207 pubmed publisher
  22. Feng H, Li X, Chan V, Chen W. Proteomics based identification of cell migration related proteins in HBV expressing HepG2 cells. PLoS ONE. 2014;9:e95621 pubmed publisher
  23. Kobayashi M, Nagashio R, Ryuge S, Murakami Y, Yanagita K, Nakashima H, et al. Acquisition of useful sero-diagnostic autoantibodies using the same patients'sera and tumor tissues. Biomed Res. 2014;35:133-43 pubmed
  24. Czuczman M, Fattouh R, van Rijn J, Canadien V, Osborne S, Muise A, et al. Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread. Nature. 2014;509:230-4 pubmed publisher
  25. Zouk H, d Hennezel E, Du X, Ounissi Benkalha H, Piccirillo C, Polychronakos C. Functional evaluation of the role of C-type lectin domain family 16A at the chromosome 16p13 locus. Clin Exp Immunol. 2014;175:485-97 pubmed publisher
  26. Drivas T, Holzbaur E, Bennett J. Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. J Clin Invest. 2013;123:4525-39 pubmed publisher
  27. Bouwman F, Wang P, van Baak M, Saris W, Mariman E. Increased ?-oxidation with improved glucose uptake capacity in adipose tissue from obese after weight loss and maintenance. Obesity (Silver Spring). 2014;22:819-27 pubmed publisher