This is a Validated Antibody Database (VAD) review about rat Angpt2, based on 6 published articles (read how Labome selects the articles), using Angpt2 antibody in all methods. It is aimed to help Labome visitors find the most suited Angpt2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Angpt2 synonym: Agpt2; Ang-2

Abcam
domestic rabbit monoclonal (EPR2891(2))
  • western blot; human; fig 6c
Abcam Angpt2 antibody (Abcam, ab155106) was used in western blot on human samples (fig 6c). Angiogenesis (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s6a
Abcam Angpt2 antibody (Abcam, ab8452) was used in western blot on mouse samples at 1:1000 (fig s6a). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; human; 1:200; loading ...; fig 2h
  • western blot; human; 1:1000
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2d
  • immunocytochemistry; mouse; 1:200; fig s4f
  • western blot; mouse; 1:1000
In order to study the role of endothelial cell exocytosis in cerebral cavernous malformation disease progression, Abcam Angpt2 antibody (Abcam, ab8452) was used in immunohistochemistry - frozen section on human samples at 1:200 (fig 2h), in western blot on human samples at 1:1000, in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 2d), in immunocytochemistry on mouse samples at 1:200 (fig s4f) and in western blot on mouse samples at 1:1000. Nat Med (2016) ncbi
domestic rabbit monoclonal (EPR2891(2))
  • western blot; human; fig 4
Abcam Angpt2 antibody (Abcam, ab155106) was used in western blot on human samples (fig 4). Endocr Relat Cancer (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:200; fig 6
In order to report angiopoietin-2 as a target in both naive and bevacizumab-treated glioblastoma, Invitrogen Angpt2 antibody (Pierce Biotechnology, PA5?\27297) was used in immunohistochemistry on human samples at 1:200 (fig 6). EMBO Mol Med (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-11)
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Santa Cruz Biotechnology Angpt2 antibody (santa Cruz, sc-74402) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1). Cancer Gene Ther (2016) ncbi
Articles Reviewed
  1. Baganha F, de Jong R, Peters E, Voorham W, Jukema J, Delibegovic M, et al. Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization. Angiogenesis. 2021;24:567-581 pubmed publisher
  2. Zhou H, Qin L, Jiang Q, Murray K, Zhang H, Li B, et al. Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model. Nat Commun. 2021;12:504 pubmed publisher
  3. Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher
  4. Li C, Li Q, Cai Y, He Y, Lan X, Wang W, et al. Overexpression of angiopoietin 2 promotes the formation of oral squamous cell carcinoma by increasing epithelial-mesenchymal transition-induced angiogenesis. Cancer Gene Ther. 2016;23:295-302 pubmed publisher
  5. Han H, Kim B, Lee J, Kang S, Kim J, Cho N. Angiopoietin-2 promotes ER+ breast cancer cell survival in bone marrow niche. Endocr Relat Cancer. 2016;23:609-23 pubmed publisher
  6. Scholz A, Harter P, Cremer S, Yalcin B, Gurnik S, Yamaji M, et al. Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma. EMBO Mol Med. 2016;8:39-57 pubmed publisher