This is a Validated Antibody Database (VAD) review about rat Acsl4, based on 21 published articles (read how Labome selects the articles), using Acsl4 antibody in all methods. It is aimed to help Labome visitors find the most suited Acsl4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Acsl4 synonym: Acs4; Facl4

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (A-5)
  • western blot knockout validation; mouse; fig 4f
Santa Cruz Biotechnology Acsl4 antibody (SantaCruz, Sc-271800) was used in western blot knockout validation on mouse samples (fig 4f). Cell (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-5)
  • western blot knockout validation; human; 1:200; loading ...; fig 4d
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, sc-271800) was used in western blot knockout validation on human samples at 1:200 (fig 4d). Nat Chem Biol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-4)
  • immunohistochemistry - paraffin section; human; loading ...; fig s1b
  • western blot; human; loading ...; fig 7f
  • western blot; mouse; loading ...; fig 3d, 6g
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, sc-365230) was used in immunohistochemistry - paraffin section on human samples (fig s1b), in western blot on human samples (fig 7f) and in western blot on mouse samples (fig 3d, 6g). Acta Pharm Sin B (2022) ncbi
mouse monoclonal (F-4)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 5j
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, sc-365230) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 5j). Nat Commun (2022) ncbi
mouse monoclonal (A-5)
  • western blot; human; 1:250; loading ...; fig 5c
  • western blot; mouse; 1:250; loading ...; fig 5p
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, sc-271800) was used in western blot on human samples at 1:250 (fig 5c) and in western blot on mouse samples at 1:250 (fig 5p). Nat Commun (2022) ncbi
mouse monoclonal (A-5)
  • western blot; mouse; 1:2000; fig s1d
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz Biotechnology, sc-271800) was used in western blot on mouse samples at 1:2000 (fig s1d). Nat Commun (2021) ncbi
mouse monoclonal (A-5)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3e
  • western blot; mouse; 1:500; loading ...; fig 3d
  • western blot; human; 1:500; loading ...; fig 4d
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, sc-271800) was used in immunohistochemistry - paraffin section on mouse samples (fig 3e), in western blot on mouse samples at 1:500 (fig 3d) and in western blot on human samples at 1:500 (fig 4d). Thorac Cancer (2021) ncbi
mouse monoclonal (F-4)
  • western blot; mouse; 1:500; loading ...; fig s1c
Santa Cruz Biotechnology Acsl4 antibody (Santa, sc-365230) was used in western blot on mouse samples at 1:500 (fig s1c). Nat Chem Biol (2020) ncbi
mouse monoclonal (A-5)
  • western blot knockout validation; mouse; fig 4f
Santa Cruz Biotechnology Acsl4 antibody (SantaCruz, Sc-271800) was used in western blot knockout validation on mouse samples (fig 4f). Cell (2018) ncbi
mouse monoclonal (A-5)
  • western blot knockout validation; human; 1:200; loading ...; fig 4d
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, sc-271800) was used in western blot knockout validation on human samples at 1:200 (fig 4d). Nat Chem Biol (2017) ncbi
mouse monoclonal (F-4)
  • western blot; human; fig 5a
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, F-4) was used in western blot on human samples (fig 5a). J Virol (2016) ncbi
mouse monoclonal (F-4)
  • western blot; human
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, sc-365230) was used in western blot on human samples . PLoS ONE (2015) ncbi
mouse monoclonal (F-4)
  • western blot; human
Santa Cruz Biotechnology Acsl4 antibody (Santa Cruz, sc-365230) was used in western blot on human samples . J Proteomics (2015) ncbi
Abcam
domestic rabbit monoclonal (EPR8640)
  • western blot; human; loading ...; fig 7d
Abcam Acsl4 antibody (Abcam, ab155282) was used in western blot on human samples (fig 7d). Front Endocrinol (Lausanne) (2022) ncbi
domestic rabbit monoclonal (EPR8640)
  • western blot; human; loading ...; fig 3a
Abcam Acsl4 antibody (Abcam, ab155282) was used in western blot on human samples (fig 3a). Sci Adv (2022) ncbi
domestic rabbit monoclonal (EPR8640)
  • western blot; human; 1:5000; fig 2c
Abcam Acsl4 antibody (abcam, ab155282) was used in western blot on human samples at 1:5000 (fig 2c). Front Mol Biosci (2021) ncbi
domestic rabbit monoclonal (EPR8640)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 6b
Abcam Acsl4 antibody (Abcam, ab155282) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 6b). elife (2021) ncbi
domestic rabbit monoclonal (EPR8640)
  • western blot; human; 1:1000; loading ...
Abcam Acsl4 antibody (abcam, ab155282) was used in western blot on human samples at 1:1000. Cell Death Differ (2021) ncbi
domestic rabbit monoclonal (EPR8640)
  • western blot; mouse; loading ...; fig 3i
Abcam Acsl4 antibody (Abcam, ab155282) was used in western blot on mouse samples (fig 3i). Cell (2019) ncbi
domestic rabbit monoclonal (EPR8640)
  • western blot; mouse; 1:2000; fig ex2h
Abcam Acsl4 antibody (abcam, ab155282) was used in western blot on mouse samples at 1:2000 (fig ex2h). Nature (2019) ncbi
domestic rabbit monoclonal (EPR8640)
  • western blot; mouse; loading ...; fig 5j
Abcam Acsl4 antibody (Abcam, ab155282) was used in western blot on mouse samples (fig 5j). Mol Cell (2017) ncbi
domestic rabbit monoclonal (EPR8640)
  • western blot; mouse; loading ...; fig 3b
Abcam Acsl4 antibody (Abcam, ab155282) was used in western blot on mouse samples (fig 3b). Lab Invest (2017) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; rat; loading ...
Invitrogen Acsl4 antibody (Invitrogen, PA5-27137) was used in western blot on rat samples . Redox Biol (2022) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s3a
Invitrogen Acsl4 antibody (Thermo Fisher, PA5-27137) was used in western blot on mouse samples (fig s3a). Sci Adv (2019) ncbi
Articles Reviewed
  1. Tong J, Li D, Meng H, Sun D, Lan X, Ni M, et al. Targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease. Acta Pharm Sin B. 2022;12:3650-3666 pubmed publisher
  2. Ji F, Fu X, Li G, He Q, Qiu X. FTO Prevents Thyroid Cancer Progression by SLC7A11 m6A Methylation in a Ferroptosis-Dependent Manner. Front Endocrinol (Lausanne). 2022;13:857765 pubmed publisher
  3. Kong Y, Akatsuka S, Motooka Y, Zheng H, Cheng Z, Shiraki Y, et al. BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance. Redox Biol. 2022;54:102356 pubmed publisher
  4. Günes Günsel G, Conlon T, Jeridi A, Kim R, Ertuz Z, Lang N, et al. The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD. Nat Commun. 2022;13:1303 pubmed publisher
  5. von M xe4 ssenhausen A, Zamora Gonzalez N, Maremonti F, Belavgeni A, Tonnus W, Meyer C, et al. Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion. Sci Adv. 2022;8:eabl8920 pubmed publisher
  6. Guo X, Zhang H, Huang J, Wang S, Lu Y, Cheng B, et al. PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca2+/Calpain/VE-Cadherin Signaling. Front Mol Biosci. 2021;8:725274 pubmed publisher
  7. Ide S, Kobayashi Y, Ide K, Strausser S, Abe K, Herbek S, et al. Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair. elife. 2021;10: pubmed publisher
  8. Bebber C, Thomas E, Stroh J, Chen Z, Androulidaki A, Schmitt A, et al. Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat Commun. 2021;12:2048 pubmed publisher
  9. Cui W, Liu D, Gu W, Chu B. Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis. Cell Death Differ. 2021;28:2536-2551 pubmed publisher
  10. Tang X, Ding H, Liang M, Chen X, Yan Y, Wan N, et al. Curcumin induces ferroptosis in non-small-cell lung cancer via activating autophagy. Thorac Cancer. 2021;12:1219-1230 pubmed publisher
  11. Kapralov A, Yang Q, Dar H, Tyurina Y, Anthonymuthu T, Kim R, et al. Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death. Nat Chem Biol. 2020;16:278-290 pubmed publisher
  12. Yang S, Harding A, Sweeney C, Miao D, Swan G, Zhou C, et al. Control of antiviral innate immune response by protein geranylgeranylation. Sci Adv. 2019;5:eaav7999 pubmed publisher
  13. Hernández Alvarez M, Sebastian D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, et al. Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease. Cell. 2019;177:881-895.e17 pubmed publisher
  14. Wang W, Green M, Choi J, Gijon M, Kennedy P, Johnson J, et al. CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy. Nature. 2019;569:270-274 pubmed publisher
  15. Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, et al. Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis. Cell. 2018;172:409-422.e21 pubmed publisher
  16. Zhao Y, Chen Y, Miao G, Zhao H, Qu W, Li D, et al. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation. Mol Cell. 2017;67:974-989.e6 pubmed publisher
  17. Xiao F, Zhang J, Zhang C, An W. Hepatic stimulator substance inhibits calcium overflow through the mitochondria-associated membrane compartment during nonalcoholic steatohepatitis. Lab Invest. 2017;97:289-301 pubmed publisher
  18. Doll S, Proneth B, Tyurina Y, Panzilius E, Kobayashi S, Ingold I, et al. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Nat Chem Biol. 2017;13:91-98 pubmed publisher
  19. Hwang K, Choi Y. Modulation of Mitochondrial Antiviral Signaling by Human Herpesvirus 8 Interferon Regulatory Factor 1. J Virol. 2016;90:506-20 pubmed publisher
  20. Yang X, Zheng K, Lin K, Zheng G, Zou H, Wang J, et al. Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study. PLoS ONE. 2015;10:e0132695 pubmed publisher
  21. Xu W, Yang X, Li D, Zheng K, Qiu P, Zhang W, et al. Up-regulation of fatty acid oxidation in the ligament as a contributing factor of ankylosing spondylitis: A comparative proteomic study. J Proteomics. 2015;113:57-72 pubmed publisher