This is a Validated Antibody Database (VAD) review about rat Abcb1b, based on 16 published articles (read how Labome selects the articles), using Abcb1b antibody in all methods. It is aimed to help Labome visitors find the most suited Abcb1b antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcb1b synonym: Abcb1; Mdr1; Pgy1; mdr1b; multidrug resistance protein 1; ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette sub-family B member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1); ATP-binding cassette, sub-family B (MDR/TAP), member 1B; ATP-binding cassette, subfamily B, member 1B; P-glycoprotein 1; P-glycoprotein/multidrug resistance 1

Knockout validation
Abcam
mouse monoclonal (JSB-1)
  • immunohistochemistry knockout validation; mouse; 1:20; fig 2
  • immunohistochemistry - paraffin section; human; fig 2
  • immunohistochemistry - paraffin section; African green monkey; fig 2
Abcam Abcb1b antibody (Abcam, JSB-1) was used in immunohistochemistry knockout validation on mouse samples at 1:20 (fig 2), in immunohistochemistry - paraffin section on human samples (fig 2) and in immunohistochemistry - paraffin section on African green monkey samples (fig 2). Drug Metab Dispos (2013) ncbi
Abcam
rabbit monoclonal (EPR10364-57)
  • immunocytochemistry; human; 1:200; fig 8a
  • western blot; human; 1:2000; fig 8b
  • immunocytochemistry; mouse; 1:200; loading ...; fig 8b
  • western blot; mouse; 1:2000; loading ...; fig 8c
Abcam Abcb1b antibody (Abcam, ab170904) was used in immunocytochemistry on human samples at 1:200 (fig 8a), in western blot on human samples at 1:2000 (fig 8b), in immunocytochemistry on mouse samples at 1:200 (fig 8b) and in western blot on mouse samples at 1:2000 (fig 8c). PLoS ONE (2017) ncbi
mouse monoclonal (JSB-1)
  • western blot; human; 1:1000; loading ...; fig 3a
Abcam Abcb1b antibody (Abcam, ab3366) was used in western blot on human samples at 1:1000 (fig 3a). Front Pharmacol (2017) ncbi
mouse monoclonal (JSB-1)
  • western blot; human; 1:1000; fig 3
Abcam Abcb1b antibody (Abcam, ab3366) was used in western blot on human samples at 1:1000 (fig 3). Biomed Res Int (2016) ncbi
mouse monoclonal (JSB-1)
  • immunocytochemistry; rat; 1:5; fig 3e
In order to test if P-glycoprotein traffics to the luminal plasma membrane of the microvessel endothelial cells from intracellular stores during peripheral inflammatory pain, Abcam Abcb1b antibody (Abcam, ab3366) was used in immunocytochemistry on rat samples at 1:5 (fig 3e). J Cereb Blood Flow Metab (2016) ncbi
rabbit monoclonal (EPR10364-57)
  • western blot; human; 1:1000; fig s6
Abcam Abcb1b antibody (Abcam, EPR10364-57) was used in western blot on human samples at 1:1000 (fig s6). Sci Rep (2016) ncbi
mouse monoclonal (JSB-1)
  • immunohistochemistry - paraffin section; human; 1:100; tbl 2
Abcam Abcb1b antibody (Abcam, ab3366) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 2). PLoS ONE (2016) ncbi
rabbit monoclonal (EPR10364-57)
  • immunocytochemistry; human; fig 1
  • immunocytochemistry; mouse; fig s2
Abcam Abcb1b antibody (Abcam, EPR10364-57) was used in immunocytochemistry on human samples (fig 1) and in immunocytochemistry on mouse samples (fig s2). J Clin Invest (2016) ncbi
rabbit monoclonal (EPR10364-57)
  • immunohistochemistry; mouse; 1:50; fig 5
Abcam Abcb1b antibody (Abcam, ab170904) was used in immunohistochemistry on mouse samples at 1:50 (fig 5). Sci Rep (2016) ncbi
rabbit monoclonal (EPR10364-57)
  • western blot; mouse; 1:500; loading ...; fig 1a,4
Abcam Abcb1b antibody (Abcam, ab170904) was used in western blot on mouse samples at 1:500 (fig 1a,4). Placenta (2015) ncbi
mouse monoclonal (JSB-1)
  • western blot; human; 1:2000; loading ...; fig 5
Abcam Abcb1b antibody (Abcam, ab3366) was used in western blot on human samples at 1:2000 (fig 5). PLoS ONE (2015) ncbi
mouse monoclonal (JSB-1)
  • immunohistochemistry - paraffin section; human; 1:20; loading ...; fig 4B
Abcam Abcb1b antibody (Abcam, JSB-1) was used in immunohistochemistry - paraffin section on human samples at 1:20 (fig 4B). J Neurotrauma (2016) ncbi
mouse monoclonal (JSB-1)
  • immunohistochemistry - frozen section; rat; 1:200
Abcam Abcb1b antibody (Abcam Lab, ab3366) was used in immunohistochemistry - frozen section on rat samples at 1:200. Pharmacol Rep (2014) ncbi
mouse monoclonal (JSB-1)
  • western blot; human
Abcam Abcb1b antibody (Abcam, ab3366) was used in western blot on human samples . Mol Biol Rep (2013) ncbi
mouse monoclonal (JSB-1)
  • immunohistochemistry - paraffin section; human; 1:40
  • western blot; human; 1:200; fig 4
Abcam Abcb1b antibody (Abcam, ab3366) was used in immunohistochemistry - paraffin section on human samples at 1:40 and in western blot on human samples at 1:200 (fig 4). Oncol Lett (2013) ncbi
mouse monoclonal (JSB-1)
  • immunohistochemistry knockout validation; mouse; 1:20; fig 2
  • immunohistochemistry - paraffin section; human; fig 2
  • immunohistochemistry - paraffin section; African green monkey; fig 2
Abcam Abcb1b antibody (Abcam, JSB-1) was used in immunohistochemistry knockout validation on mouse samples at 1:20 (fig 2), in immunohistochemistry - paraffin section on human samples (fig 2) and in immunohistochemistry - paraffin section on African green monkey samples (fig 2). Drug Metab Dispos (2013) ncbi
Invitrogen
mouse monoclonal (JSB-1)
  • immunohistochemistry - paraffin section; human
In order to assess the extent and prognostic significance of MDR-related protein expression in ovarian serous carcinomas and correlate their expression with apoptosis-related proteins, Invitrogen Abcb1b antibody (Zymed, JSB-1) was used in immunohistochemistry - paraffin section on human samples . Gynecol Oncol (2006) ncbi
Articles Reviewed
  1. Sekhar G, Georgian A, Sanderson L, Vizcay Barrena G, Brown R, Muresan P, et al. Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB). PLoS ONE. 2017;12:e0173474 pubmed publisher
  2. Okada N, Murakami A, Urushizaki S, Matsuda M, Kawazoe K, Ishizawa K. Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X Receptor. Front Pharmacol. 2017;8:84 pubmed publisher
  3. Li L, Liu H, Wang C, Liu X, Hu F, Xie N, et al. Overexpression of ?-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma. Biomed Res Int. 2016;2016:5378567 pubmed publisher
  4. Tome M, Herndon J, Schaefer C, Jacobs L, Zhang Y, Jarvis C, et al. P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain. J Cereb Blood Flow Metab. 2016;36:1913-1928 pubmed
  5. Cederbye C, Palshof J, Hansen T, Duun Henriksen A, Linnemann D, Stenvang J, et al. Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue. Sci Rep. 2016;6:26997 pubmed publisher
  6. Sato K, Suda K, Shimizu S, Sakai K, Mizuuchi H, Tomizawa K, et al. Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression. PLoS ONE. 2016;11:e0154186 pubmed publisher
  7. Kim D, Bynoe M. A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier. J Clin Invest. 2016;126:1717-33 pubmed publisher
  8. Aikawa H, Hayashi M, Ryu S, Yamashita M, Ohtsuka N, Nishidate M, et al. Visualizing spatial distribution of alectinib in murine brain using quantitative mass spectrometry imaging. Sci Rep. 2016;6:23749 pubmed publisher
  9. Wang C, Li H, Luo C, Li Y, Zhang Y, Yun D, et al. The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure. Placenta. 2015;36:1138-47 pubmed publisher
  10. St George M, Ayoub A, Banerjee A, Churchill C, Winter P, Klobukowski M, et al. Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells. PLoS ONE. 2015;10:e0129168 pubmed publisher
  11. Willyerd F, Empey P, Philbrick A, Ikonomovic M, Puccio A, Kochanek P, et al. Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans. J Neurotrauma. 2016;33:226-31 pubmed publisher
  12. Alvariza S, Fagiolino P, Vázquez M, Feria Romero I, Orozco Suárez S. Chronic administration of phenytoin induces efflux transporter overexpression in rats. Pharmacol Rep. 2014;66:946-51 pubmed publisher
  13. Li W, Zhong S, Wu Y, Xu W, Xu J, Tang J, et al. Systematic expression analysis of genes related to multidrug-resistance in isogenic docetaxel- and adriamycin-resistant breast cancer cell lines. Mol Biol Rep. 2013;40:6143-50 pubmed
  14. Xie J, Li D, Chen X, Wang F, Dong P. Expression and significance of hypoxia-inducible factor-1? and MDR1/P-glycoprotein in laryngeal carcinoma tissue and hypoxic Hep-2 cells. Oncol Lett. 2013;6:232-238 pubmed
  15. Yasuda K, Cline C, Vogel P, Onciu M, Fatima S, Sorrentino B, et al. Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier. Drug Metab Dispos. 2013;41:923-31 pubmed publisher
  16. Yakirevich E, Sabo E, Naroditsky I, Sova Y, Lavie O, Resnick M. Multidrug resistance-related phenotype and apoptosis-related protein expression in ovarian serous carcinomas. Gynecol Oncol. 2006;100:152-9 pubmed